锌指蛋白与肝细胞癌的研究进展

张恒; 张成; 廖伟然; 何宇涛; 章宇洋; 杜斌; 王琳

doi:10.12259/j.issn.2095-610X.S20220135

锌指蛋白与肝细胞癌的研究进展

doi: 10.12259/j.issn.2095-610X.S20220135

昆明医科大学第二附属医院肝胆外科二病区，云南昆明　650101

基金项目: 国家自然科学基金资助项目（ 81660399）；昆明医科大学研究生创新基金资助项目（ 2021S205）

详细信息

作者简介:
张恒（1995～），男，江西抚州人，在读硕士研究生，主要从事肝癌基础研究工作

通讯作者:
王琳，E-mail：wanglinfey@126.com

中图分类号: R735.5
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- 被引次数: 0
出版历程
- 收稿日期: 2021-12-11
- 网络出版日期: 2021-12-20
- 刊出日期: 2022-01-15

Research Progress of Zinc Finger Protein and Hepatocellular Carcinoma

The 2nd Ward of Hepatobiliary Surgery，The 2nd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China

摘要

摘要: 由于肝细胞癌的发生与发展机理复杂，目前还未充分揭示。作为人体基因组中规模最大的转录因子家族，锌指蛋白现已证实在包括肝癌在内的许多癌症中起到了关键性作用，现将对探讨锌指蛋白的构成、类型，以及在肝细胞癌中的作用机制方面进行综述。
- 锌指蛋白 /
- 肝癌 /
- 基因调控 /
- 转录因子
Abstract: Due to its complicated mechanism, the occurrence and development of hepatocellular carcinoma have not been fully revealed yet. As the largest transcription factor family in the human genome, zinc finger proteins have been confirmed to play a key role in many cancers, including liver cancer. The mechanism of action is reviewed in this article.
- Zinc finger protein /
- Liver cancer /
- Gene regulation /
- Transcription factor

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参考文献(44)

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