甲状腺癌发病的危险因素及预防策略研究进展

吴华杰; 张楠; 李磊; 乔涵; 李国萍

doi:10.12259/j.issn.2095-610X.S20220526

甲状腺癌发病的危险因素及预防策略研究进展

doi: 10.12259/j.issn.2095-610X.S20220526

云南省肿瘤医院头颈肿瘤外科，云南昆明　650118

基金项目: 国家自然科学基金资助项目（82060499），云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目（202101AY070001-174）

详细信息

作者简介:
吴华杰（1993～），男，安徽芜湖人，医学学士，主要从事头颈肿瘤的基础与临床研究工作。张楠与吴华杰对本文有同等贡献

通讯作者:
李国萍，E-mail：liguoping5@126.com

中图分类号: R739.91
计量
- 文章访问数: 4315
- HTML全文浏览量: 2415
- PDF下载量: 141
- 被引次数: 0
出版历程
- 收稿日期: 2022-01-15
- 网络出版日期: 2022-05-13
- 刊出日期: 2022-05-27

Research Progress in the Risk Factors and Prevention Strategies of Thyroid Cancer

The Head and Neck Department of Yunnan Tumor Hospital，Kunming Yunnan 650118，China

摘要

摘要:
甲状腺癌是内分泌系统最常见的恶性肿瘤，其发病率在世界范围内逐年上升。甲状腺癌的发病原因尚不完全明确，放射性暴露、代谢综合征（包括肥胖、高血压、高血脂、糖尿病等）以及不良饮食和生活习惯、环境污染等可增加甲状腺癌的罹患风险。减少辐射暴露，控制血压、血脂、血糖和体重，改善生活习惯等可降低甲状腺癌的发病风险。本文对甲状腺癌发病的危险因素及预防策略进行综述。
- 甲状腺癌 /
- 病因 /
- 危险因素 /
- 预防策略
Abstract:
Thyroid cancer is the most common malignant tumor in endocrine system. Its morbidity is increasing worldwide year by year. The exact cause of thyroid cancer is still unclear. Radiation exposure, metabolic syndrome （such as obesity, hypertention, hyperlipidemia and diabetes）, unhealthy life style, and environmental pollution are involved in the pathogenesis and development of thyroid cancer. Avoiding radiation exposure, controlling blood pressure, blood fat, blood glucose and body weight, improving life habits can be valid measures to prevent thyroid tumor. This paper is to summarize the risk factors and prevention measures of thyroid cancer.
- Thyroid cancer /
- Pathogeny /
- Risk factors /
- Prevention measures

HTML全文

参考文献(33)

[1]	Maria Laura Iglesias,Angelica Schmidt,Abir Al Ghuzlan,et al. Radiation exposureand thyroid cancer:A review study[J]. Arch Endocrinol Metab,2017,61(2):180-187. doi: 10.1590/2359-3997000000257
[2]	Mi Ah Han,Jin Hwa Kim. Diagnostic X-ray exposure and thyroid cancer risk:Systematic review and meta-analysis[J]. Thyroid,2018,28(2):220-228. doi: 10.1089/thy.2017.0159
[3]	Jiajun Luo,Nicole C Deziel,Huang Huang,et al. Cell phone use and risk of thyroid cancer:A population-based case control study in connecticut[J]. Ann Epidemiol,2019,29(1):39-45.
[4]	Jiajun Luo,Hang Li,Nicole C Deziel,et al. Genetic susceptibility may modify the association between cell phone use and thyroid cancer:A population-based case-control study in Connecticut[J]. Environ Res,2020,182(3):109-113.
[5]	Sylvie Mesrine,Marina Kvaskoff,Thierno Bah,et al. Nevi,ambient ultravioletradiation,and thyroid cancer risk:A French prospective study[J]. Epidemiology,2017,28(5):694-702. doi: 10.1097/EDE.0000000000000673
[6]	Jina Kim,Jessica E Gosnell,Sanziana A Roma. Geographic influences in the globalrise of thyroid cancer[J]. Nat Rev Endocrinol,2020,16(1):17-29. doi: 10.1038/s41574-019-0263-x
[7]	Seung-Kwon Myung,Chan Wha Lee,Jeonghee Lee,et al. Risk factors for thyroid cancer:A hospital-based case-control study in Korean adults[J]. Cancer Res Treat,2017,49(1):70-78. doi: 10.4143/crt.2015.310
[8]	Haiyoung Son,Hakmin Lee,Keera Kang. et al. The risk of thyroid cancer and obesity:A nationwide population-based study using the Korea National Health Insurance Corporation cohort database[J]. Surg Oncol,2018,27(2):166-171. doi: 10.1016/j.suronc.2018.03.001
[9]	Bin Song,Zhihua Zuo,Juan Tan,et al. Association of thyroid nodules with adiposity:A community-based cross-sectional study in China[J]. BMC EndocrDisord,2018,18(1):3-10.
[10]	Danuta Gasior-Perczak,Iwona Patyga,Monika Szymonek. The impact of BMI on clinical progress response to treatment,and disease course in patients with differentiated thyroid cancer[J]. PLoS One,2018,13(10):460-468.
[11]	De-Tao Yin,Huanan He,Kun Yu et al. The association between thyroid cancer and insulin resistance,metabolic syndrome and its components:A systematic review and meta-analysis[J]. Int J Surg,2018,57(9):66-75.
[12]	Borena W,Stocks T,Jonason H,et al. Serum triglyceridesand cancer risk in the metabolic syndrome and cancer(Me-Can)collaborative study[J]. Cancer Causes Control,2011,22(2):291-299. doi: 10.1007/s10552-010-9697-0
[13]	周建华. 2型糖尿病血糖、血脂代谢情况与甲状腺癌发病的相关性[J]. 实用癌症杂志,2017,32(2):314-316. doi: 10.3969/j.issn.1001-5930.2017.02.043
[14]	曾幸,刘慧霞,萧梅芳,等. 甲状腺癌在2型糖尿病患者中患病情况及相关因素分析[J]. 中国普通外科杂志,2019,29(5):558-564.
[15]	方红,许慧琳,刘奕男,等. 1205例2型糖尿病患者的恶性肿瘤流行病学特征[J]. 中国肿瘤,2013,22(5):370-374.
[16]	Ara Cho,Yoosoo Chang,Jiin Ahn,et al. Cigarette smoking and thyroid cancer risk:A cohort study[J]. Br J Cancer,2018,119(5):638-645. doi: 10.1038/s41416-018-0224-5
[17]	Cari M Kitahara,Martha S Linet,Laura E Beane Freeman,et al. Cigarette smoking,alcohol intake,and thyroid cancer risk:A pooled analysis of five prospective studies in the United States[J]. Cancer Causes Control,2012,23(10):1615-1624.
[18]	Yang Gyeong Yoo,Boas J Yu,Eun-Hi Choi,et al. A comparison study:The risk factors in the lifestyles of thyroid cancer patients and healthy adults of the republic of Korea[J]. Cancer Urs,2018,41(1):48-56.
[19]	白超,杨雯雯,张丽,等. 微量元素碘、硒、铜、锌与甲状腺乳头状癌的相关性研究[J]. 新疆医学,2019,49(3):235-239.
[20]	郭振清,赵腾,孙谟健,等. 青岛地区1306例甲状腺癌的临床病理特征分析[J]. 中国癌症杂志,2016,11(1):53-59.
[21]	Hye J K,Hyeong K P,Dong W B,et al. Iodine intake as a risk factor for BRAF mutations in papillary thyroid cancer patients from an iodine-replete area[J]. Eur J Nutr,2016,24(5):76-83.
[22]	Wuq,Rayman M P,Lyu H. Low population selenium status is associated with increased prevalence of thyroid disease[J]. J Clin Endocrinol Metab,2015,100(11):4037-4047. doi: 10.1210/jc.2015-2222
[23]	Zimmermann M B,Galetti V. Iodine intake as a risk factor for thyroid cancer:A comprehensive review of animal and human studies[J]. Thyroid Res,2015,8(1):8-14. doi: 10.1186/s13044-015-0020-8
[24]	Junyu Zhao,Haipeng Wang,Zhongwen Zhang,et al. Vitamin D deficiency as a risk factor for thyroid cancer:A meta-analysis of case-control studies[J]. Nutrition,2019(1):5-11.
[25]	Su Kyoung Jung,Kirang Kim,Kyung Tae,et al. The effect of raw vegetable and fruit intake on thyroid cancer risk among women:A case-control study in the republic of Korea[J]. Br J Nutr,2013,109(1):118-128. doi: 10.1017/S0007114512000591
[26]	Fiore E,Vitti P. Serum TSH and risk of papillary thyroid cancer in nodular thyroid disease[J]. Clin Endocrinol Metab,2012,97(4):1134-1145. doi: 10.1210/jc.2011-2735
[27]	Danilovic D L,Ferraz-DE-Souza B,Fabri A W,et al. 25-Hydroxyvitamin D and TSH as risk factors or prognostic markers in thyroid carcinoma[J]. Plos One,2016,11(10):1645-1655.
[28]	Sangah Shin,Norie Sawada,Eiko Saito,et al. Menstrual and reproductive factors in the risk of thyroid cancer in Japanese women:The Japan Public Health Center-Based Prospective Study[J]. Eur J Cancer Prev,2018,27(4):361-369. doi: 10.1097/CEJ.0000000000000338
[29]	David Jackson,Rachel S Handelsman,Josefina C Farrá,et al. Increased incidental thyroid cancer in patients with subclinical chronic lymphocytic thyroiditis[J]. J Surg Res,2020,245(1):115-118.
[30]	TPilli,P Toti,R Occhini,et al. Chronic lymphocytic thyroiditis has a positive prognostic value in papillary thyroid cancer (PTC) patients:The potential key role of Foxp3+ T lymphocytes[J]. J Endocrinol Invest,2018,41(6):703-709. doi: 10.1007/s40618-017-0794-8
[31]	Anastasios apanastasiou,KonstantinosSapalidis,Dimitrios G Goulis,et al. Thyroid nodules as a risk factor for thyroid cancer in patients with Graves' disease:A systematic review and meta-analysis of observational studies in surgically treated patients[J]. Clin Endocrinol,2019,91(4):571-577. doi: 10.1111/cen.14069
[32]	Lee J,Lee C R,Ku C R,et al. Association between obesity and BRAFV600E mutation status in patients with aillary thyroid cancer[J]. Ann Surg Oncol,2015,22(3):683-690.
[33]	Mi Ah Han,Jin Hwa Kim,Han Soo Song. Persistent organic pollutants,pesticides,and the risk of thyroid cancer:Systematic review and meta-analysis[J]. Eur J Cancer Prev,2019,28(4):344-349. doi: 10.1097/CEJ.0000000000000481

相关文章(20)

[1]	李梦, 牛奔, 胡瑾, 马燕琳. 免疫检查点抑制剂引起肿瘤患者甲状腺功能障碍的临床分析, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20240111
[2]	周敏, 马智慧, 李加艳, 范建华, 林灵, 余亭颖, 张慧芳, 刘立. 肝硬化并胸水再发危险因素的预测, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20220524
[3]	贾万优, 刘红莉, 蒋薇薇, 李红敏, 张硕, 费继敏. 甲状腺术后甲状旁腺功能减退的风险因素, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20220904
[4]	何迪, 陈鹏, 刘锋, 徐杨, 韩磊, 丁文静. 肝纤维化病因与机制研究进展, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20221122
[5]	张彩营, 奎正平, 王琼, 赵小龙, 侯晓梅, 齐志业. 新生儿高促甲状腺素血症围产期危险因素分析, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20220929
[6]	孟泽祖, 鲜航, 侯晓进, 魏石磊, 马继, 赵睿, 丛锐. 断指再植术后血管危象相关危险因素, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20210122
[7]	张锡华, 贾涛, 刘伟涛, 万青, 王锦峰, 李溪, 刘劲松. 髋关节强直的病因与治疗现状, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20210902
[8]	孙健玮, 向茜, 刘子超, 徐珊珊, 丁丁. PTEN基因表达对甲状腺癌BCPAP和FTC133细胞凋亡以及ERK和AKT表达的影响, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20210805
[9]	李磊, 杨洁, 王伟霖, 王虎. 合并桥本氏甲状腺炎的甲状腺癌外科治疗, 昆明医科大学学报.
[10]	戴梅. 昆明市儿童哮喘的危险因素分析, 昆明医科大学学报.
[11]	李明. 男性乳腺癌研究及治疗现状, 昆明医科大学学报.
[12]	王玉. 儿童再发性腹痛72例常见病因分析, 昆明医科大学学报.
[13]	张红红. 昆明地区学龄前女童同性性早熟病因及临床特点分析, 昆明医科大学学报.
[14]	年英华. 超声对结节性甲状腺肿合并甲状腺癌的诊断及误诊分析, 昆明医科大学学报.
[15]	毕丹青. 胃肠外科手术后急性肾损伤病因分析, 昆明医科大学学报.
[16]	李国萍. 宫颈及甲状腺多原发癌11例临床分析, 昆明医科大学学报.
[17]	孙瑞梅. Focus超声刀在早期甲状腺癌（T1N0M0）术中的应用研究, 昆明医科大学学报.
[18]	徐芳. 早产病因237例分析, 昆明医科大学学报.
[19]	. 胸腔积液74例病因临床诊断分析, 昆明医科大学学报.
[20]	杨秋萍. 心血管危险因素聚集与心率变异性的关系研究, 昆明医科大学学报.