赫特维希上皮根鞘细胞的研究进展

毕菲; 郭维华

doi:10.12259/j.issn.2095-610X.S20220628

赫特维希上皮根鞘细胞的研究进展

doi: 10.12259/j.issn.2095-610X.S20220628

毕菲^{1, 2},
郭维华^{1, 2, ,}

1.
四川大学华西口腔医院儿童口腔科，四川成都　610041
2.
口腔疾病研究国家重点实验室，四川成都　610041

基金项目: 国家自然科学基金资助项目（31971281）；四川省科技创新人才项目（2022JDRC0043）；四川大学华西口腔医院探索与研发项目（RD-03-202106）

详细信息

作者简介:
毕菲（1995～），女，云南昆明人，在读硕士研究生，主要从事儿童口腔早期矫治临床工作及牙源性干细胞相关基础研究工作

通讯作者:
郭维华，E-mail：guoweihua943019@163.com

中图分类号: R78
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- 文章访问数: 2453
- HTML全文浏览量: 2090
- PDF下载量: 50
- 被引次数: 0
出版历程
- 收稿日期: 2022-03-28
- 网络出版日期: 2022-06-08
- 刊出日期: 2022-06-30

Advances in Research on Hertwig’s Epithelial Root Sheath Cells

Fei BI^{1, 2},
Weihua GUO^{1, 2
, ,}

1.
Dept. of Pediatric Dentistry，West China School of Stomatology，Sichuan University，Chengdu，China 610041
2.
State Key Laboratory of Oral Diseases，West China Hospital of Stomatology，Sichuan University，Chengdu 610041，China

摘要

摘要: 赫特维希上皮根鞘（Hertwig’s epithelial root sheath, HERS）细胞是一群在牙根发育以及牙周组织形成过程中发挥重要作用的特殊细胞。就HERS细胞起源、形态结构，以及近年来关于其生物学行为特点、参与牙发育调控过程、应用于组织修复再生潜力的研究作一综述，为后续HERS细胞及其衍生物在牙周组织再生中的应用策略和机制探究提供参考。
- 赫特维希上皮根鞘细胞 /
- 牙根发育 /
- 上皮-间充质转化 /
- 上皮-间充质相互作用 /
- 牙周组织再生
Abstract: Hertwig's epithelial root sheath （HERS） cells are a special group of cells that play important roles during root development and formation of periodontal tissues. This paper summarizes the origin and morphological structure of HERS cells, as well as the recent researches on their biological behaviors, participation in the regulatory process of tooth development, and potential application to tissue repair and regeneration. It provides a reference for the subsequent study on application strategies and mechanisms of HERS cells and their derivatives in periodontal tissue regeneration.
- Hertwig’s epithelial root sheath cells /
- tooth root development /
- epithelial-mesenchymal transition /
- epithelial-mesenchymal interaction /
- periodontal tissue regeneration

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参考文献(69)

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赫特维希上皮根鞘细胞的研究进展

doi: 10.12259/j.issn.2095-610X.S20220628

作者简介:
毕菲（1995～），女，云南昆明人，在读硕士研究生，主要从事儿童口腔早期矫治临床工作及牙源性干细胞相关基础研究工作

通讯作者:
郭维华，E-mail：guoweihua943019@163.com

计量

Advances in Research on Hertwig’s Epithelial Root Sheath Cells

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目录

[1]	郭小兵, 李晓文, 李恒希, 曹艳, 李坪. miR-212-3p靶向调控NAP1L1抑制胶质瘤细胞增殖、迁移和上皮-间充质转化, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20241104
[2]	李鹏, 邹仁超, 代龙翱, 傅嵩洲, 魏东, 唐波. HIF-1α通过调控上皮-间充质转化对胆囊癌侵袭转移的影响, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20240507
[3]	杨镕羽, 宋飞, 黄浩, 段开文, 向盈盈. 骨髓间充质干细胞在口腔医学中的应用, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20230323
[4]	马丽娅, 饶南荃, 杨禾丰. 间充质干细胞外泌体在口腔组织再生中的研究进展, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20210527
[5]	李京辉, 朱明, 曲海, 李秋宇, 吴玉娟, 杨贺英, 王郁竹, 李妍平. miR-490-3p调控SW1990胰腺癌细胞上皮间充质转化, 昆明医科大学学报. doi: 10.12259/j.issn.2095-610X.S20210305
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[11]	易敏. 兔骨髓间充质干细胞的培养及初步鉴定, 昆明医科大学学报.
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[16]	毛希宏. 人脐带间充质干细胞的培养鉴定及其向神经元细胞分化的研究, 昆明医科大学学报.
[17]	邰文琳. 小鼠骨髓间充质干细胞体外扩增的实验研究, 昆明医科大学学报.
[18]	黄颖. 人脐带间充质干细胞对再生障碍性贫血患者T细胞相关因子调节的体外研究, 昆明医科大学学报.
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[20]	杨锋. 两种培养方法在猪自体骨髓间充质干细胞培养的比较研究, 昆明医科大学学报.

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赫特维希上皮根鞘细胞的研究进展

doi: 10.12259/j.issn.2095-610X.S20220628

作者简介: 毕菲（1995～ ），女，云南昆明人，在读硕士研究生，主要从事儿童口腔早期矫治临床工作及牙源性干细胞相关基础研究工作

通讯作者: 郭维华，E-mail：guoweihua943019@163.com

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Advances in Research on Hertwig’s Epithelial Root Sheath Cells

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作者简介:
毕菲（1995～），女，云南昆明人，在读硕士研究生，主要从事儿童口腔早期矫治临床工作及牙源性干细胞相关基础研究工作

通讯作者:
郭维华，E-mail：guoweihua943019@163.com