Analysis of Genital Chlamydia Trachomatis Infection and Related Factors among Premarital Examination Population in Some Areas of Yunnan Province
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摘要:
目的 了解云南省部分地区婚检人群生殖道沙眼衣原体(chlamydia trachomatis,CT)感染情况,为制定防控措施以及效果评估提供依据。 方法 采用横断面调查,选取云南省保山市、德宏州、红河州、临沧市、普洱市和西双版纳州婚检人群进行问卷调查,并采集尿液/宫颈分泌物样本进行CT核酸检测。 结果 共纳入研究对象1671例,总的人群感染率为6.64%(111/1671,95%CI:5.40%~7.80%)。其中男性感染率4.99%(42/841,95%CI:3.50%~6.50%),女性感染率8.31%(69/830,95%CI:6.40%~10.20%)。不同州市CT阳性率差异有统计学意义(P = 0.043),其中普洱市、德宏州和临沧市的感染率较高,为8.87%(29/327),8.64%(26/301)和7.94%(25/315)。年龄18~20岁(AOR = 4.346,95%CI:1.468~12.707)和文化程度为初中及以下的(AOR = 1.854,95%CI:1.071~3.211)更可能感染CT。 结论 云南省部分地区婚检人群中CT感染率具有地区、年龄和文化程度的差异。应加强性病防治知识的健康教育,进一步加强性病的检测能力,加大筛查力度和动员检测,尽可能地发现传染源,并进行规范化的治疗,以有效地控制生殖道沙眼衣原体的传播与流行。 Abstract:Objectives To investigate the infection status of reproductive tract chlamydia trachomatis (CT) in premarital examination population in Yunnan Province, and to provide basis for prevention and control measures and effect evaluation. Methods A cross-sectional survey was conducted among the premarital examination population in Baoshan City, Dehong Prefecture, Honghe Prefecture, Lincang City, Pu’er City and Xishuangbanna Prefecture of Yunnan Province, and the urine/cervical secretion samples were collected for CT nucleic acid detection. Results A total of 1671 individuals were enrolled in this study. The overall CT prevalence in this population was 6.64% (111/1671, 95% CI: 5.40%~7.80%), the prevalence among male and female were 4.99% (42/841, 95% CI: 3.50%~6.50%), and 8.31% (69/830, 95% CI: 6.40%~10.20%), respectively. The CT positive rates among the individuals attending premarital examination in different prefectures were statistically different (P = 0.043), which were relatively higher in Pu’er City (8.87%, 29/327), Dehong Prefecture (8.64%, 26/301) and Lincang City (7.94%, 25/315) . Aged ≤ 20 years (AOR = 4.346, 95%CI: 1.468~12.707) and education level of junior middle school and below (AOR = 1.854, 95%CI: 1.071~3.211) were more likely to be infected with CT. Conclusion The prevalence of CT among the premarital examination population showed statistical difference when stratified by region, age and education level. The health education on STD prevention knowledge and the testing ability of STD should be strengthened. The effective control of CT infection should be achieved by increasing the intensity of screening, finding the source of infection and carrying out standardized treatment. -
表 1 婚检人群CT感染影响因素分析
Table 1. Analysis of influencing factors of CT infection in premarital examination population
变量 合计 感染人数(n) 感染率(%) 单因素分析 多因素分析 P OR(95%CI) P AOR(95%CI) 州市 0.054 0.043* 保山市 316 12 3.80 — 1.000 — 1.000 红河州 343 15 4.37 0.971 0.986(0.468~2.078) 0.556 1.301(0.542~3.119) 西双版纳州 69 4 5.80 0.333 1.685(0.586~4.846) 0.202 2.200(0.655~7.382) 德宏州 301 26 8.64 0.012* 2.317(1.119~4.477) 0.014* 2.649(1.219~5.755) 临沧市 315 25 7.94 0.178 1.612(0.804~3.232) 0.160 1.877(0.780~4.518) 普洱市 327 29 8.87 0.048* 1.954(1.005~3.801) 0.013* 2.708(1.231~5.954) 年龄(岁) < 0.001* < 0.001* ≥41 89 5 5.62 — 1.000 — 1.000 31~40 324 19 5.86 0.930 1.047(0.380~2.886) 0.738 1.192(0.426~3.341) 21~30 1162 67 5.77 0.952 1.029(0.404~2.622) 0.558 1.332(0.510~3.480) 18~20 96 20 20.83 0.005* 4.364(1.562~12.194) 0.007* 4.346(1.468~12.707) 性别 男 841 42 4.99 — 1.000 — 1.000 女 830 69 8.31 0.007* 1.725(1.161~2.564) 0.084 1.446(0.952~2.196) 民族 汉族 1030 61 5.92 — 1.000 其他 641 50 7.80 0.178 1.299(0.888~1.900) 文化程度 高中及以上 586 26 4.44 — 1.000 — 1.000 初中及以下 1085 85 7.83 0.009* 1.831(1.166~2.875) 0.028* 1.854(1.071~3.211) 户籍 本省 1604 106 6.61 — 1.000 非本省 67 5 7.46 0.783 1.140(0.449~2.895) 职业 农民 951 72 7.57 — 1.000 — 1.000 其他 720 39 5.42 0.081 0.699(0.468~1.045) 0.454 1.243(0.703~2.199) 月平均经济收入(元) 0.408 ≥5000 235 12 5.11 — 1.000 3000~5000 461 26 5.64 0.709 1.104(0.657~1.855) 2000~3000 662 51 7.70 0.433 0.791(0.440~1.422) ≤2000 313 22 7.01 0.358 0.712(0.345~1.469) *P < 0.05。 -
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