Clinical Significance of Uterine Artery and Luteal Blood Flow Doppler Parameters Pregnancy of Uncertain Viability
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摘要:
目的 探讨子宫动脉及黄体血流多普勒参数在早期妊娠不确定丢失中的临床意义。 方法 以64例早期妊娠胚胎存活力不确定的孕妇为研究对象,经阴道超声检查测量其子宫动脉及黄体血流参数,以随访后的明确诊断为依据,将不可存活宫内妊娠者纳入研究组,可存活宫内妊娠者纳入对照组。 结果 不可存活妊娠组mUAPI(2.16±0.50)、mUARI(0.82±0.07),低于可存活妊娠组mUAPI(2.93±0.48)、mUARI(0.89±0.05),差异有统计学意义(P < 0.05);不可存活妊娠组黄体血流PI(0.85±0.13)、RI(0.56±0.06)、高于对照组黄体血流PI(0.75±0.13)、黄体血流RI(0.50±0.06),差异有统计学意义(P < 0.05)。 结论 子宫动脉及黄体血流搏动指数对早期存活力不确定妊娠临床咨询有指导意义。 Abstract:Objective To explore the clinical significance of uterine artery and luteal flow Doppler parameters in pregnancy of uncertain viability. Methods A total of 64 women with pregnancy of uncertain viability in first trimester were selected as the research subjects. The uterine artery and luteal blood flow parameters were measured by transvaginal ultrasound. Based on the definite diagnosis after follow-up, non-viable intrauterine pregnancies were included in the study group, and viable intrauterine pregnancies were included in the control group. Results The mUAPI (2.16±0.50) and mUARI (0.82±0.07) in the non-viable pregnancy group were significantly lower than the mUAPI (2.93±0.48) and mUARI (0.89±0.05) in the viable pregnancy group, with statistically significant differences (P < 0.05). The luteal blood flow PI (0.85±0.13) and RI (0.56±0.06) in the non-viable pregnancy group were significantly higher than the luteal blood flow PI (0.75±0.13), luteal blood flow RI (0.50±0.06) in control group, with statistically significant ( P < 0.05). Conclusion Uterine artery and corpus luteum blood flow Doppler parameters are useful for guiding clinical consultations in pregnancies of uncertain viability. -
Key words:
- Ultrasonography /
- Abortion /
- Uterine artery /
- Corpus luteum
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表 1 2组孕妇人口统计学特征及临床资料[($\bar x \pm s $)/n(%)]
Table 1. Demographic characteristics and clinical data of pregnant women in the two groups [($\bar x \pm s $)/n(%)]
人口统计学及临床特征 不可存活妊娠组 可存活妊娠组 χ2/t P 年龄(岁) 29.32 ± 5.08 27.00 ± 4.85 1.870 0.066 体重(kg) 54.00 ± 7.54 55.52 ± 10.07 −0.678 0.501 BMI(kg/㎡) 21.12 ± 3.02 21.52 ± 3.47 0.319 0.626 平均动脉压(mmHg) 85.35 ± 6.87 83.25 ± 5.78 1.024 0.067 停经时间(d) 49.4 ± 7.8 46.2 ± 8.3 1.768 0.089 是否吸烟 是 2(6.46) 1(3.03) 0.607# 否 29(93.54) 32(96.97) 孕次 1次(首次怀孕) 10(32.26) 11(33.33) 0.008 0.927 ≥2次 21(67.74) 22(66.67) 产次 0次(未经产) 14(45.16) 19(57.58) 0.986 0.321 ≥1次 17(54.84) 14(42.42) 血清hCG(IU/L) 7752.97 ± 4240.45 13926.00 ± 4958.90 −4.351 < 0.001* 胚芽 可见 6(19.35) 5(15.15) 0.198 0.656 未见 25(80.65) 28(84.85) 平均孕囊直径(mm) 14.8 ± 6.7 9.9 ± 3.7 3.609 0.001* BMI为体质指数(体重除以身高的平方);*P < 0.05。#该处P值由FISHER确切概率法所得,故无χ2值。 表 2 2组子宫动脉及黄体血流多普勒参数比较($\bar x \pm s $)
Table 2. Comparison of Doppler ultrasound parameters of uterine artery and luteal blood flow between two groups ($\bar x \pm s $)
组别 n 子宫动脉多普勒参数 黄体血流多普勒参数 mUARI mUAPI RI PI 不可存活组 31 0.82 ± 0.07 2.16 ± 0.50 0.56 ± 0.06 0.85 ± 0.13 可存活组 33 0.89 ± 0.05 2.93 ± 0.48 0.50 ± 0.06 0.75 ± 0.13 t −4.297 −6.228 3.481 3.001 P < 0.001* < 0.001* 0.001* 0.004* *P < 0.05。 -
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