Risk Factors of Gastroesophageal Reflux in Patients with Swallowing Disorders
-
摘要: 吞咽功能障碍严重影响人民群众的身心健康,已成为一个重大的临床医疗及公共卫生问题。GERD是吞咽障碍患者常见的并发症之一,与吞咽功能障碍有非常显著的相关性。正确掌握吞咽障碍患者GERD危险因素,早期识别可能发生GERD的高危人群,在临床护理过程中积极采取预防对策,对降低吞咽障碍患者GERD的发生率有着重要的临床意义和价值。目前,未见吞咽功能障碍发生GERD的流行病学调查研究,对GERD的机制及其造成的误吸的影响因素研究也较少。对吞咽障碍患者发生GERD的危险因素进行文献综述,旨在为临床早期预防提供参考依据。Abstract: Swallowing disorders seriously affect people’s physical and mental health and has become a major clinical and public health problem. GERD is one of the common complications in patients with dysphagia and has a very significant correlation with swallowing dysfunction. Risk factors of GERD in patients with dysphagia should be identified, so as to detect the high-risk population of GERD early, and actively take preventive measures in the process of clinical nursing, which has important clinical significance and value to reduce the incidence of GERD in patients with dysphagia. At present, there are no epidemiological studies on GERD caused by swallowing dysfunction, and there are few studies on the mechanism of GERD and the influencing factors of aspiration caused by GERD. To review the risk factors of gastroesophageal reflux disease (GERD) in patients with dysphagia so as to provide a reference for early clinical prevention. At present, there are no epidemiological studies on GERD in swallowing disorder patients, and there are few studies on the mechanism of GERD and the influencing factors of aspiration. This paper reviews the risk factors of GERD in patients with dysphagia, and provides reference for early clinical prevention.
-
Key words:
- Swallowing disorders /
- Gastroesophageal reflux disease /
- Risk factors /
- Literature review
-
[1] McCarty E B,Chao T N. Dysphagia and swallowing disorders[J]. Medical Clinics,2021,105(5):939-954. [2] Wilkinson J M,Codipilly D C,Wilfahrt R P. Dysphagia:Evaluation and collaborative management[J]. American Family Physician,2021,103(2):97-106. [3] 阿里木·买买提,陶发明,祖里培亚·艾拜都拉,等. 胃食管反流相关性慢性咳嗽并咽喉反流患者的反流特征[J]. 中华胃食管反流病电子杂志,2020,7(3):172-176. doi: 10.3877/cma.j.issn.2095-8765.2020.03.008 [4] Sweis R,Fox M. The global burden of gastro-oesophageal reflux disease:More than just heartburn and regurgitation[J]. The Lancet Gastroenterology & Hepatology,2020,5(6):519-521. [5] Michels G,Motzko M,Weinert M,et:al. Management of dysphagia in internal intensive-care medicine[J]. Medizinische Klinik - Intensivmedizin und Notfallmedizin,2015,110(3):174-181. doi: 10.1007/s00063-014-0386-8 [6] Srivastava R,Jackson W D,Barnhart D C. Dysphagia and gastroesophageal reflux disease:Dilemmas in diagnosis and management in children with neurological impairment[J]. Pediatric Annals,2010,39(4):225-231. doi: 10.3928/00904481-20100318-07 [7] 谭纪萍,刘瑛,王鑫,等. 中国人口老龄化发展趋势与老年健康研究现状[J]. 中国老年学杂志,2012,32(19):3. [8] Muhle P,Wirth R,Glahn J,et al. Age-related changes in swallowing Physiology and pathophysiology[J]. Nervenarzt,2015,86(4):440-451. doi: 10.1007/s00115-014-4183-7 [9] Azzolino D,Damanti S,Bertagnoli L,et al. Sarcopenia and swallowing disorders in older people[J]. Aging Clinical and Experimental Research,2019,31(6):799-805. doi: 10.1007/s40520-019-01128-3 [10] Ortega O,Martín A,Clavé P. Diagnosis and management of oropharyngeal dysphagia among older persons,state of the art[J]. Journal of the American Medical Directors Association,2017,18(7):576-582. [11] 李丹,胡艳宁. 老年吞咽障碍患者风险管理研究进展[J]. 中国老年学杂志,2021,41(6):1340-1343. doi: 10.3969/j.issn.1005-9202.2021.06.060 [12] Hota S,Inamoto Y,Oguchi K,et al. Outcomes of dysphagia following stroke:Factors influencing oral intake at 6 months after onset[J]. Journal of Stroke and Cerebrovascular Diseases,2021,30(9):105971. [13] Chang C S,Chen H J,Liao C H. Patients with cerebral stroke have an increased risk of gastroesophageal reflux disease:A population-based cohort study[J]. Journal of Stroke and Cerebrovascular Diseases,2018,27(5):1267-1274. doi: 10.1016/j.jstrokecerebrovasdis.2017.12.001 [14] 孙予祥,贾雪丽,廖书帆,等. 吞咽康复对头颈癌患者吞咽功能及生活质量效果的Meta分析[J]. 中国康复理论与实践,2019,25(7):751-760. [15] 苏英,刘清. 气管插管机械通气患者拔管后获得性吞咽功能障碍危险因素分析[J]. 护士进修杂志,2022,37(3):276-279. doi: 10.16821/j.cnki.hsjx.2022.03.016 [16] Truitt M,Kwok A,Friese R,etal. Post-extubation dysphagia in trauma patients:it's hard to swallow Discussion[J]. The American Journal of Surgery,2013,206(6):927-928. [17] 李超,张梦清,窦祖林,等. 中国特定人群吞咽功能障碍的流行病学调查报告[J]. 中华物理医学与康复杂志,2017,39(12):937-943. [18] 张泊宁,马静,吕丽娟,等. 2000—2016年我国吞咽功能障碍护理文献的计量分析[J]. 中华现代护理杂志,2018,24(18):2156-2160. [19] Ojo O,Brooke J. The use of enteral nutrition in the management of stroke[J]. Nutrients,2016,8(12):E827. [20] 葛茜茜,马文华,柯玲珍. 急性缺血性脑卒中患者营养支持现状调查及其营养不良影响因素分析[J]. 实用预防医学,2020,27(6):737-739. [21] Katzka D A,Kahrilas P J. Advances in the diagnosis and management of gastroesophageal reflux disease[J]. BMJ,2020,371:m3786. [22] 杨俊锋,王留根,李和平,等. 舌咽神经阻滞治疗对胃食管反流病致咽期吞咽障碍的临床疗效[J]. 河南医学研究,2020,29(15):2737-2739. [23] 钟炼东,詹添福,钟超. 胃食管反流患者出现假性失弛缓症和吞咽困难的临床特征和危险因素分析[J]. 中国医学工程,2020,28(7):91-93. [24] Eusebi L H,Ratnakumaran R,Yuan Y,et al. Global prevalence of,and risk factors for,gastro-oesophageal reflux symptoms:A meta-analysis[J]. Gut,2018,67(3):430-440. doi: 10.1136/gutjnl-2016-313589 [25] Surdea-Blaga T,Negrutiu D E,Palage M,et al. Food and gastroesophageal reflux disease[J]. Current Medicinal Chemistry,2019,26(19):3497-3511. [26] 周金池,赵曙光,王新,等. 中国部分地区基于社区人群胃食管反流病患病率Meta分析[J]. 胃肠病学和肝病学杂志,2020,29(9):1012-1020. doi: 10.3969/j.issn.1006-5709.2020.09.012 [27] 吴继敏,汪忠镐,胡志伟,等. 中国胃食管反流病多学科诊疗共识[J]. 中华胃食管反流病电子杂志,2020,7(1):1-28. [28] Pauletti R N,Callegari-Jacques S M,Fornari L,et al. Reduced masticatory function predicts gastroesophageal reflux disease and esophageal dysphagia in patients referred for upper endoscopy:A cross-sectional study[J]. Digestive and Liver Disease,2022,54(3):331-335. [29] Jurkiewicz D,Waśko-Czopnik D,Pietruszewska W,et al. Gastroesophageal reflux disease–from the point of view of a gastroenterologist,otolaryngologist and surgeon[J]. Otolaryngologia Polska,2021,75(2):42-50. doi: 10.5604/01.3001.0014.8478 [30] 刘龙. 胃食管反流病的康复治疗研究现状[J]. 当代医药论丛,2022,20(4):5. doi: 10.3969/j.issn.2095-7629.2022.04.006 [31] 马英阁. 激励式护理干预对胃食管反流病患者腹腔镜术后治疗效果,负性情绪及生活质量的影响[J]. 首都食品与医药,2020,27(14):147. [32] 陈玲红,吴雅鋆,曾清芳. 胃食管反流病的食管动力异常机制及治疗进展[J]. 现代消化及介入诊疗,2021,26(6):789-792. doi: 10.3969/j.issn.1672-2159.2021.06.031 [33] 中华医学会消化病学分会. 2020年中国胃食管反流病专家共识[J]. 中华消化杂志,2020,40(10):649-663. doi: 10.3760/cma.j.cn311367-20200918-00558 [34] Nawaz S,Tulunay-Ugur O E. Dysphagia in the older patient[J]. Otolaryngologic Clinics of North America,2018,51(4):769-777. doi: 10.1016/j.otc.2018.03.006 [35] Chen M Y,Lin L C. Nonimaging clinical assessment of impaired swallowing in community-dwelling older adults in Taiwan[J]. The Journal of Nursing Research:JNR,2012,20(4):272-280. [36] Wolf U,Eckert S,Walter G,et al. Prevalence of oropharyngeal dysphagia in geriatric patients and real-life associations with diseases and drugs[J]. Scientific reports,2021,11(1):1-14. doi: 10.1038/s41598-020-79139-8 [37] Otaki F,Iyer P G. Gastroesophageal reflux disease and Barrett esophagus in the elderly[J]. Clinics in Geriatric Medicine,2021,37(1):17-29. [38] Oskretkov V I,Gankov V A,Andreasyan A R,et al. Gastroesophageal reflux after laparoscopic hiatal hernia repair in patients with axial hiatal hernia[J]. Khirurgiia,2020(6):38-43. [39] 李军祥,陈誩,李岩. 胃食管反流病中西医结合诊疗共识意见(2017年)[J]. 中国中西医结合消化杂志,2018,26(3):221-226,232. [40] Okamoto N,Tomioka K,Saeki K,et al. Relationship between swallowing problems and tooth loss in community‐dwelling independent elderly adults:The fujiwara‐kyo study[J]. Journal of the American Geriatrics Society,2012,60(5):849-853. [41] 支梦佳,王田田,洪晓露,等. 北京市社区老年人吞咽障碍发生现状及其危险因素研究[J]. 护理管理杂志,2019,19(11):834-838. doi: 10.3969/j.issn.1671-315x.2019.11.018 [42] 丁瑜,徐月,王丽媛,侯惠如. 高龄长期鼻饲患者胃食管反流与胃残余量的相关性及其危险因素分析[J]. 解放军医学院学报,2018,39(5):380-383. doi: 10.3969/j.issn.2095-5227.2018.05.005 [43] Li C H,Hsieh T C,Hsiao T H,et al. Different risk factors between reflux symptoms and mucosal injury in gastroesophageal reflux disease[J]. Kaohsiung Journal of Medical Sciences,2015,31(6):320-327. doi: 10.1016/j.kjms.2015.02.007 [44] Schindler A,Pizzorni N,Mozzanica F,et al. Functional outcomes after supracricoid laryngectomy:what do we not know and what do we need to know?[J]. European Archives of Oto-Rhino-Laryngology,2015,273(11):1-17. [45] 王桂玲. 脑卒中后鼻饲患者胃食管反流病的临床调查分析[J]. 中国实用神经疾病杂志,2015,18(17):83-84. doi: 10.3969/j.issn.1673-5110.2015.17.054 [46] Na’amnih W,Ben Tov A,Bdair-Amsha A,et al. Physicians’ adherence to management guidelines for H. pylori infection and gastroesophageal reflux disease:A cross-sectional study[J]. Israel Journal of Health Policy Research,2020,9(1):1-7. [47] 饶利,吴海燕,敬仁芝. 预见性护理模式对老年卒中后胃食管反流患者的干预效果观察[J]. 实用医院临床杂志,2021,18(2):77-79. doi: 10.3969/j.issn.1672-6170.2021.02.022 [48] 秦昶,郭石平. 管状胃在预防食管癌术后胃食管反流中的作用[J]. 临床医药文献电子杂志,2018,5(14):50-51. doi: 10.3877/j.issn.2095-8242.2018.14.034 [49] Andalib A,Bouchard P,Demyttenaere S,et al. Esophageal cancer after sleeve gastrectomy:A population-based comparative cohort study[J]. Surgery for Obesity and Related Diseases,2021,17(5):879-887. [50] Patel DA,Krishnaswami S,Steger E,et al. Conover E economic and survival burden of dysphagia among inpatients in the united states[J]. Dis Esophagus,2018,31(1):1-7. [51] 覃慧敏,唐丹喆,施惠芳,等. 脑卒中后吞咽障碍患者病耻感现状及影响因素研究[J]. 护理学杂志,2018,33(9):15-17. [52] Bai P,Bano S,Kumar S,et al. Gastroesophageal reflux disease in the young population and its correlation with anxiety and depression[J]. Cureus,2021,13(5):e15289. [53] 陈琰,隋昕珂,黄鑫,等. 反流性食管炎患者食管外症状的危险因素分析[J]. 解放军医学志,2021,46(8):808-811. [54] Quach D T,Pham Q T T,Tran T L T,et al. Clinical characteristics and risk factors of gastroesophageal reflux disease in vietnamese patients with upper gastrointestinal symptoms undergoing esophagogastroduodenoscopy[J]. JGH Open,2021,5(5):580-584. doi: 10.1002/jgh3.12536 [55] Schuitenmaker J M,van Dijk M,Oude Nijhuis R A B,et al. Associations between sleep position and nocturnal gastroesophageal reflux:A study using concurrent monitoring of sleep position and esophageal pH and impedance[J]. The American Journal of Gastroenterology,2022,117(2):346-351. doi: 10.14309/ajg.0000000000001588 [56] 翁霞美,魏秀娟,李萍. 用改良式留置胃管法为存在吞咽功能障碍的脑卒中患者留置胃管的效果研究[J]. 当代医药论丛,2020,18(4):105-106. [57] Skoretz S A,Flowers H L,Martino R. The incidence of dysphagia following endotracheal intubation:A systematic review[J]. Chest,2010,137(3):665-673. doi: 10.1378/chest.09-1823 [58] 刘思彤,黄迎春,彭南海. 危重患者行肠内营养期间发生反流误吸护理安全策略研究进展[J]. 临床普外科电子杂志,2017,5(4):74-77. doi: 10.3969/j.issn.2095-5308.2017.04.018 [59] 谢恋,卢慧英,王瑞瑜,等. 老年吸入性肺炎的危险因素分析及风险预测模型构建[J]. 广州医药,2022,53(2):12-16,22. doi: 10.3969/j.issn.1000-8535.2022.02.003 [60] 颜国慧,桑宝珍. 脑卒中后胃食管反流预见性护理的应用分析[J]. 护理研究,2010,24(7):609-610. [61] Wu S J. Preventive care for aspiration pneumonia in patients with an indwelling nasogastric tube[J]. Hu Li Za Zhi,2022,69(1):18-24. [62] 郭斌艳. 不同胃管留置长度对脑卒中合并吞咽障碍患者的影响[J]. 护理实践与研究,2020,17(21):139-141. [63] 安德连,窦祖林,唐志明,等. 注食速度对吞咽障碍患者间歇注食时返流及误吸的影响[J]. 深圳中西医结合杂志,2019,29(23):104-105. [64] 杜金磊,聂臣聪,雷玲,等. 护理康复方案在机械通气患者获得性吞咽功能障碍中的应用效果[J]. 中国当代医药,2022,29(9):171-175. doi: 10.3969/j.issn.1674-4721.2022.09.046 [65] Brodsky M B,Huang M,Shanholtz C,et al. Recovery from ddysphagia ssymptoms after ooral eendotracheal iintubation in aacute rrespiratory ddistress ssyndrome ssurvivors. A 5-yyear longitudinal sstudy[J]. Annals of the American Thoracic Society,2017,14(3):376. doi: 10.1513/AnnalsATS.201606-455OC [66] 万娜,王艳玲,张春艳,等. ICU患者获得性吞咽障碍发生现状及危险因素分析[J]. 中国护理管理,2018,18(11):1467-1471. [67] 张敏洁. 危重症患者胃食管反流的临床诊断研究[D]. 长沙: 中南大学硕士学位论文, 2012. [68] 张慧慧,赵伟英,王志娟,等等. ICU机械通气患者误吸评估方法及风险因素评估的研究进展[J]. 护理与康复,2017,16(2):130-134. [69] 刘硕,肖宏. 气管切开鼻饲患者误吸原因及护理进展[J]. 中国误诊学杂志,2011,11(35):8592-8593. [70] 陈维顺,李舜午,彭苏娜,等. 危重症患者胃食管反流的临床诊断研究[J]. 临床消化病杂志,2013,25(5):307-309. doi: 10.3870/1cxh.j.issn.1005-541X.2013.05.18 [71] 赵晓敏,滕丽洁. 颅脑损伤病人早期留置胃管预防返流误吸及对其预后的影响[J]. 实用临床护理学电子杂志,2018,3(42):16,26. [72] Sella-Weiss O. Association between swallowing function,malnutrition and frailty in community dwelling older people[J]. Clinical Nutrition ESPEN,2021,45:476-485. [73] 魏从光,魏晓艳,郝润春. 胃食管反流病的临床研究进展[J]. 武警医学,2020,31(6):542-545. doi: 10.3969/j.issn.1004-3594.2020.06.025
点击查看大图
计量
- 文章访问数: 4166
- HTML全文浏览量: 2142
- PDF下载量: 29
- 被引次数: 0