Effect of Nutritional Intervention Combined with Resistance Exercise on Senile Sarcopenia
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摘要:
目的 探析营养干预联合抗阻运动在老年肌少症中应用价值，为临床制定有效干预方案提供参考依据。 方法 采用目的抽样法，选取2020年8月至2022年5月在昆明市第二人民医院老年病科收治的50例老年肌少症患者为研究对象，依据病案号前后次序将其分为观察组与对照组，各25例。对照组采用常规饮食、康复锻炼及护理；观察组在对照组基础上予以营养干预联合抗阻运动，2组患者均干预2个月。干预前后分别测定患者血清白蛋白（albumin，ALB）、血红蛋白（hemoglobin，Hb）及维生素D（vitamin D，VD）水平；运用整体营养评定量表（Patient Generated-Subjective Global Assessment，PG-SGA）评估患者干预前后营养水平；运用改良Barthel指数量表评定干预前后日常生活能力。 结果 观察组患者Hb、ALB及VD高于对照组，PG-SGA评分低于对照组，差异有统计学意义（P < 0.05）；观察组患者日常生活能力高于对照组，差异有统计学意义（P < 0.05）。 结论 营养干预联合抗阻运动可快速恢复老年肌少症患者营养水平，并提高其日常生活能力。 Abstract:Objective To explore the application value of nutrition intervention combined with resistance exercise in senile sarcopenia, and to provide evidence for clinical intervention programs. Methods From August 2020 to May 2022, purposive sampling was used to select 50 patients with sarcopenia admitted to the Geriatrics Department of the Second People's Hospital of Kunming as the research subject. According to the order of the medical record number, they were divided into observation group and control group, with 25 cases in each group. The control group received routine diet, rehabilitation exercise and nursing, and the observation group received nutritional intervention combined with resistance exercise as well as the treatment of control group. Patients in both groups were treated for 2 months, and serum albumin （ALB）, hemoglobin （Hb） and vitamin D （VD） levels were measured before and after intervention. Patient Generated-Subjective Global Assessment （PG-SGA） was used to evaluate the nutritional levels of patients before and after intervention. The modified Barthel index was used to evaluate daily living ability before and after intervention. Results Hb, ALB and VD in observation group were higher than those in control group, PG-SGA score was lower than that in control group, the difference was statistically significant （P < 0.05）. The daily living ability of observation group was higher than that of control group, and the difference was statistically significant （P < 0.05）. Conclusion Nutritional intervention combined with anti-resistance exercise can quickly restore the nutritional level of senile patients with sarcopenia and improve their daily living ability. -
表 1 2组患者常规信息对比（
$\bar x \pm s $ ）Table 1. Comparison of basic information between the two groups （
$\bar x \pm s $ ）项目 对照组（n = 25） 观察组（n = 25） t/χ2 P 年龄（岁） 65.87 ± 5.19 65.31 ± 5.16 0.276 0.784 性别（n，男/女） 13/12 14/11 0.081 0.777 体质量指数（kg/m2） 18.51 ± 3.46 18.45 ± 3.54 0.061 0.952 体重（kg） 64.64 ± 11.63 65.68 ± 10.96 0.325 0.747 脂肪含量（%） 13.58 ± 4.52 13.17 ± 4.43 0.324 0.747 握力（kg） 24.03 ± 7.44 25.28 ± 8.71 0.546 0.588 骨骼肌质量指数（kg/m2） 4.99 ± 0.49 4.89 ± 0.29 0.878 0.384 
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表 2 2组患者营养水平比较（
$\bar x \pm s $ ）Table 2. Comparison of nutritional levels between the two groups （
$\bar x \pm s $ ）指标 时间 对照组（n = 25） 观察组（n = 25） Hb（g/L） 干预前 112.86 ± 11.18 114.72 ± 9.89 干预后 120.07 ± 11.32* 128.32 ± 14.49*# ALB（g/L） 干预前 30.77 ± 4.55 31.08 ± 4.23 干预后 34.09 ± 5.89* 38.46 ± 6.01*# VD（ng/mL） 干预前 17.01 ± 5.34 17.34 ± 5.72 干预后 21.34 ± 7.01* 25.89 ± 6.71*# PG-SGA评分（分） 干预前 8.61 ± 0.74 8.64 ± 0.49 干预后 5.05 ± 1.16* 2.04 ± 0.91*# 与本组干预前相比，*P < 0.05；与对照组相比，#P < 0.05。
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表 3 2组患者日常生活能力比较（分，
$\bar x \pm s $ ）Table 3. Comparison of daily living ability between the two groups （points，
$\bar x \pm s $ ）指标 时间 对照组（n = 25） 观察组（n = 25） 穿脱衣物 干预前 4.58 ± 0.56 4.76 ± 0.47 干预后 6.75 ± 0.69* 9.49 ± 0.44*# 二便控制 干预前 4.17 ± 0.91 4.12 ± 0.89 干预后 6.34 ± 0.27* 9.49 ± 0.37*# 平地行走 干预前 4.81 ± 0.92 4.95 ± 0.87 干预后 6.98 ± 0.91* 9.33 ± 0.39*# 上下楼梯 干预前 4.46 ± 0.72 4.24 ± 0.95 干预后 6.69 ± 0.54* 9.27 ± 0.32*# 独立进食 干预前 4.05 ± 0.23 4.17 ± 0.38 干预后 6.21 ± 0.29* 9.39 ± 0.21*# 独立洗漱 干预前 4.58 ± 0.64 4.74 ± 0.72 干预后 6.51 ± 0.59* 9.77 ± 0.21*# 与本组干预前相比，*P < 0.05；与对照组相比，#P < 0.05。
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