Application Value of Nutritional Risk Screening 2002 in Elderly COPD Patients with Dysphagia
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摘要:
目的 应用营养风险筛查2002(nutritional risk screening 2002,NRS 2002)量表评估老年慢性阻塞性肺疾病(Chronic obstructive lung disease,COPD)合并吞咽障碍患者住院时的营养风险发生率,并探究NRS 2002在临床中的应用价值。 方法 选取2021年11月至2022年10月在云南省第三人民医院全科医学科收治的老年COPD合并吞咽障碍患者124例,根据评分结果将患者分为NRS≥3组(n = 69例)和NRS < 3组(n = 55例)。比较2组的一般资料及营养相关生化指标(总蛋白、白蛋白和前白蛋白),并进行相关性分析。 结果 老年COPD合并吞咽障碍患者营养风险发生率为55.6%,存在营养风险的患者中80岁以上占84.0%(P < 0.05),营养风险评分≥3分组的总蛋白、白蛋白、前白蛋白水平和BMI值均低于 < 3分组(P < 0.05)。采用Spearman相关分析显示,营养风险评分与年龄、住院时间、住院费用呈正相关(P < 0.05),与营养学相关指标(总蛋白、白蛋白、前白蛋白、BMI)水平呈负相关(P < 0.05)。单因素方差分析结果显示, NRS 2002评分、总蛋白、白蛋白、BMI的均值在不同吞咽障碍等级的患者中,总体分布差异具有统计学意义(P < 0.05),各组间前白蛋白水平差异均无统计学意义(P﹥0.05)。 结论 老年COPD合并吞咽障碍患者营养风险发生率高(55.6%),NRS 2002可作为老年COPD合并吞咽障碍患者的早期营养风险筛查,早期识别患者的营养风险,采取积极干预措施,预防老年COPD患者吞咽障碍的发生。 -
关键词:
- 慢性阻塞性肺疾病 /
- 老年 /
- 吞咽障碍 /
- 营养风险筛查2002量表 /
- 营养风险
Abstract:Objective To evaluate the incidence of nutritional risk in hospitalized elderly patients with chronic obstructive pulmonary disease complicated with dysphagia with the Nutritional Risk Screening 2002 scale, and to explore the clinical application value of NRS 2002. Methods A total of 124 elderly patients with COPD complicated with swallowing disorder admitted to the Department of General Medicine of the Third People’s Hospital of Yunnan Province from November 2021 to October 2022 were selected. The patients were divided into NRS≥3 group (n = 69 cases) and NRS < 3 group (n = 55 cases). The general data and nutrition-related biochemical indexes (total protein, albumin, and prealbumin) of the two groups were compared, and a correlation analysis was performed. Results The incidence of nutritional risk in elderly COPD patients with dysphagia was 55.6%. Among the patients with nutritional risk, 84.0% were over 80 years old (P < 0.05). The levels of total protein, albumin, prealbumin and BMI of nutritional risk score ≥3 group were lower than those of group with < 3 (P < 0.05). Spearman correlation analysis showed that the nutritional risk score was positively correlated with age, length of stay, and hospitalization cost (P < 0.05), and negatively correlated with the levels of nutrition-related indicators (total protein, albumin, prealbumin and BMI) (P < 0.05). The results of one-way ANOVA showed that there were statistically significant differences (P < 0.05) in the mean values of NRS 2002 score, total protein, albumin, and BMI among patients with different levels of swallowing disorders. However, there was no statistically significant difference (P > 0.05) in the levels of pre-albumin among the groups. Conclusion Elderly COPD patients with swallowing disorders have a high incidence of nutritional risk (55.6%). NRS 2002 can be used as an early nutritional risk screening tool for elderly COPD patients with swallowing disorders. Early identification of nutritional risk in patients and taking proactive intervention measures can prevent the occurrence of swallowing disorders in elderly COPD patients. -
表 1 不同营养评分组的患者基本特征比较[
$\bar x \pm s $ /n(%)]Table 1. Comparison of basic characteristics of patients with different nutritional rating groups [
$\bar x \pm s $ /n(%)]参数 所有患者(n = 124) NRS 2002评分≥3分组(n = 69) NRS 2002评分 < 3 分组(n = 55) P 性别 男
女104(83.9)
20(16.1)61(78.2)
8(21.8)43(88.4)
12(11.6)0.124 年龄(岁)
60~79
80岁以上83.4 ± 8.5
33(26.6)
91(73.4)86.3 ± 7.3
11(16.0)
58(84.0)79.8 ± 8.5
22(40.0)
33(60.0)< 0.001* 住院时间(d)
< 10
10~15
> 1512.2 ± 3.9
29(23.4)
74(59.7)
21(16.9)13.1 ± 3.9
10(14.5)
44(63.8)
15(21.7)11.1 ± 3.8
19(34.6)
30(54.6)
6(10.8)0.006* 住院总费用(元)
< 10 000
≥10 00012973.8 ± 6850.9
49(39.5)
75(60.5)14594.3 ± 7860.3
22(31.9)
47(68.1)10940.9 ± 4640.9
27(49.0)
28(51.0)0.003* 实验室检查 总蛋白(g/L) 65.0 ± 8.5 62.9 ± 7.4 67.7 ± 9.1 0.002* 白蛋白(g/L) 37.6 ± 5.6 35.7 ± 5.1 39.9 ± 5.2 < 0.001* 前白蛋白(mg/L) 192 ± 62.6 171.6 ± 61.2 217 ± 54.7 < 0.001* BMI(kg/m2) 20.9 ± 3.4 18.7 ± 2.1 23.6 ± 2.9 < 0.001* NRS 2002评分≥3分组与 < 3 分组间比较,*P < 0.05;BMI为体质指数。 表 2 NRS 2002评分与患者临床指标之间的相关性
Table 2. Correlation between NRS 2002 scores and patient clinical indicators
项目 r P 性别 −0.138 0.126 年龄 0.402 < 0.001* 住院时间 0.244 0.006* 住院总费用 0.269 0.003* 总蛋白 −0.336 < 0.001* 白蛋白 −0.400 < 0.001* 前白蛋白 −0.363 < 0.001* BMI −0.711 < 0.001* *P < 0.05。 表 3 不同吞咽障碍等级间NRS 2002评分及各营养相关指标分布差异(
$\bar x \pm s $ )Table 3. Differences of NRS 2002 scores and nutrition-related indexes among different levels of swallowing disorders (
$\bar x \pm s $ )吞咽障碍等级 n NRS 2002 总蛋白 白蛋白 前白蛋白 BMI 2级 62 1.6 ± 1.2 66.7 ± 7.7 39.0 ± 4.9 200.2 ± 59.7 22.1 ± 3.7 3级 49 3.0 ± 1.0# 63.7 ± 9.7# 36.4 ± 6.3# 184.0 ± 69.1 20.0 ± 3.0# 4级 10 3.6 ± 0.9# 60.2 ± 6.2# 34.1 ± 4.0# 185.4 ± 45.1 18.3 ± 2.4# 5级 3 3.7 ± 0.6# 71.3 ± 4.0 38.7 ± 3.1 176.3 ± 62.6 17.2 ± 0.7# F 18.464 2.868 3.440 0.720 7.779 P < 0.001* 0.039* 0.019* 0.542 < 0.001* *P < 0.05;与2级比较,#P < 0.05。 -
[1] 张瑞,常艳,张晓娜,等. 老年慢性阻塞性肺疾病患者吞咽障碍发生现状及影响因素分析[J]. 中华护理杂志,2022,57(23):2898-2904. doi: 10.3761/j.issn.0254-1769.2022.23.012 [2] Li W,Gao M,Liu J,et al. The prevalence of oropharyngeal dysphagia in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis[J]. Expert Rev Respir Med,2022,16(5):567-574. doi: 10.1080/17476348.2022.2086123 [3] Ghannouchi I,Speyer R,Doma K,et al. Swallowing function and chronic respiratory diseases: Systematic review[J]. Respir Med,2016,117:54-64. [4] Chaves R D, Carvalho C R F, Cukier A, et al. Symptoms of dysphagia in patients with COPD[J]. J Bras Pneumol, 2011, 37(2): 176-183. [5] Nagami S , Oku Y , Yagi N , et al. Breathing-swallowing discoordination associated with frequent exacerbation of COPD[C]//ERS International Congress 2017 abstracts. 2017, 4(1): e000202. [6] 张瑞,芦鸿雁,吴珍珍,等. 老年慢性阻塞性肺疾病患者营养状况对吞咽功能的影响[J]. 宁夏医科大学学报,2021,43(06):649-654. doi: 10.16050/j.cnki.issn1674-6309.2021.06.017 [7] 许静涌,杨剑,康维明. 营养风险及营养风险筛查工具营养风险筛查2002临床应用专家共识( 2018 版)[J]. 中华临床营养杂志,2018,6(26):131-135. [8] 李幼霞,黄煌,蔡水江,等. 营养风险评估在新型冠状病毒肺炎治疗中的应用价值[J]. 广东医学,2022,43(10):1205-1209. [9] 赵丽新,王亚妹,程小敏,等. 急性心肌梗死患者营养风险评估及影响因素分析[J]. 中国食物与营养,2022,28(6):64-67. [10] 高从荣,范军,裴韶华,等. 食管癌患者术前营养风险评估及与术后吻合口瘘和住院时间的关系研究[J]. 现代生物医学进展,2022,22(16):3132-3136. [11] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组,中国医师协分会慢性阻塞性肺疾病工作委员会. 慢性阻塞性肺疾病诊治指南(2021年修订版会呼吸医师)[J]. 中华结核和呼吸志,2021,44(3):170-205. [12] 刘妮,郑则广,李有霞,等. 洼田饮水试验和简单2步吞咽激发试验评估慢性阻塞性肺疾病急性加重期患者误吸的应用价值[J]. 中国实用内科杂志,2019,39(10):904-908. doi: 10.19538/j.nk.2019100115 [13] 赵小芳,姜春燕. 老年人常用营养风险筛查工具的研究进展[J]. 中国全科医学,2018,21(22):2768-2772. [14] 熊胜,杨中善,熊宇. 成人住院患者营养风险筛查工具的特点及有效性分析[J]. 临床消化病杂志,2018,30(6):378-382. doi: 10.3870/lcxh.j.issn.1005-541X.2018.06.011 [15] Zhang Peiyan,Wang Qi,Zhu Mengran,et al. Differences in nutritional risk assessment between NRS2002,RFH-NPT and LDUST in cirrhotic patients.[J]. Scientific reports,2023,13(1):3306-3306. doi: 10.1038/s41598-023-30031-1 [16] Kondrup J,Rasmussen H H,Hamberg O,et al. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials[J]. Clinical Nutrition,2003,22(3):321-336. doi: 10.1016/S0261-5614(02)00214-5 [17] 路露,李媛,雷新宁,等. PG-SGA量表与NRS 2002量表对肺癌病人营养风险预测效果的对比研究[J]. 全科护理,2023,21(14):1895-1897. [18] 嵇云鹏,熊世娟,陈琦,等. 呼吸系统疾病住院患者的营养状况及影响因素[J]. 贵州医科大学学报,2023,48(4):472-477. [19] 张萍萍,张婷,冯海洋,等. 潍坊市养老院老年人吞咽障碍与误吸调查[J]. 中国康复理论与实践,2022,28(04):467-472. [20] 黄洁,李承红. 慢性阻塞性肺疾病营养不良研究进展[J]. 中国老年学杂志,2016,36(1):242-245. [21] Ohta K K T. Evaluation of swallowing function by two screening tests in primary COPD[J]. The European Respiratory Journal,2009,34(1):280-281.