颞下颌关节骨关节炎分子致病机制的研究进展

陈一晗; 张善勇; 丁昱; 张莉

doi:10.12259/j.issn.2095-610X.S20240701

颞下颌关节骨关节炎分子致病机制的研究进展

doi: 10.12259/j.issn.2095-610X.S20240701

陈一晗¹,
张善勇²,
丁昱¹,
张莉^1, ,

1.
云南大学附属医院口腔医学中心，云南昆明　650021
2.
上海交通大学医学院附属第九人民医院口腔外科，上海　200011

基金项目: 国家自然科学基金资助项目（82071135）；云南省省级临床重点专科开放课题（ZKF2024033）

详细信息

作者简介:
陈一晗（2000～），女，福建平潭人，医学学士，住院医师，主要从事颞颌关节紊乱病临床研究工作

通讯作者:
张莉，E-mail：13658898675@139.com

中图分类号: R578
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出版历程
- 收稿日期: 2024-03-05
- 网络出版日期: 2024-06-05
- 刊出日期: 2024-07-25

Research Progress on the Molecular Pathogenesis of Temporomandibular Joint Osteoarthritis

1.
Stomatological Center，Affiliated Hospital of Yunnan University，Kunming Yunnan 650021
2.
Shanghai Ninth People’s Hospital，Shanghai Jiao Tong University School of Medicine，Shanghai 200011，China

More Information

Corresponding author: 张莉， 1993年毕业于华西医科大学口腔医学院，现任云南大学附属医院口腔医学中心主任医师，颞下颌关节疾病多学科诊疗团队副组长，口腔医学中心科研管理组组长，参与组建省内首个颞下颌关节疾病 MDT 诊疗团队。担任国家级住院医师规范化培训口腔颌面外科基地主任，口腔住院医师规范化培训结业考核考官，口腔执业医师资格实践技能考试考官；中华口腔医学会第七届颞下颌关节病学及牙合学专业委员会委员，中华预防医学会口腔卫生保健专业委员会委员，云南省口腔医学会第一口腔预防专业委员会副主任委员，云南省口腔医学会第一、二届口腔颌面外科专业委员会委员。主持及参与6项各级各类科研项目。以通讯作者及第一作者发表国家级核心期刊论文24篇，获2项授权专利。

摘要

摘要: 颞下颌关节骨关节炎（temporomandibular joint osteoarthritis，TMJOA）是发生于颞颌关节结构的1种慢性退行性病变，但TMJOA的发病机制仍未完全阐明。随着研究方法的进步，TMJOA的研究开始深入到基因层面，对近年来颞下颌关节骨关节炎发病机制的分子生物研究的进展进行综述。
- 颞下颌关节 /
- 骨关节炎 /
- 致病机制
Abstract: Temporomandibular joint osteoarthritis （TMJOA） is a chronic degenerative condition affecting the structures of the temporomandibular joint. Despite ongoing research efforts, the pathogenesis of TMJOA is not yet fully understood. Recent advancements in research techniques have allowed for a deeper exploration of the genetic factors underlying TMJOA. This article will provide an overview of the most recent developments in molecular biology research related to the pathogenesis of temporomandibular joint osteoarthritis.
- Temporomandibular joint /
- Osteoarthritis /
- Pathogenesis

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参考文献(42)

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