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RSS2016 Vol. 37, No. 09
2016, 37(09)
Abstract:
［Abstract］Duraphat fluoride varnish is a topical coating material applied to tooth surfaces composed of fluoride compound, film-forming material and volatile solvent and containing 5% sodium fluoride (22,600 ppm Fluoride). Many studies have shown the effectiveness of Duraphat fluoride varnishes in inhibiting caries, reducing tooth mineralization and releasing hypersensitive dentine. This article aims to review the research on clinical application of Duraphat fluoride varnish
［Abstract］Duraphat fluoride varnish is a topical coating material applied to tooth surfaces composed of fluoride compound, film-forming material and volatile solvent and containing 5% sodium fluoride (22,600 ppm Fluoride). Many studies have shown the effectiveness of Duraphat fluoride varnishes in inhibiting caries, reducing tooth mineralization and releasing hypersensitive dentine. This article aims to review the research on clinical application of Duraphat fluoride varnish
2016, 37(09)
Abstract:
［Abstract］Objective To study the effects of Yunnan BaiYao on the expressions of c-fos and c-jun mRNA in HPDLFs and explore the potential mechanism that Yunnan BaiYao promotes the proliferation and differentiation of HPDLFs．Methods The HPDLFs tissue was obtained from the extracted healthy premolar．The HPDLFs used underwent four to six passages．Cells were divided into untreated group， positive control group and treated group. In treated group，HPDLFs were co-cultured with Yunnan BaiYao solution for 4h with gradient concentration. The expressions of c-fos and c-jun mRNA were determined by RT-PCR．Results The results showed that the expressions of c-fos and c-jun mRNA were up-regulated significantly in treated group compared with control group（P＜0.05）．Conclusion Yunnna BaiYao can upregulate the expressions of c-fos and C-jun mRNA in HPDLFs. Through upregulating the expressions of c-fos and c-jun mRNA in hPDLs，Yunnan BaiYao can promote proliferation and differentiation of ossification of HPDLFs to induce bone formation.
［Abstract］Objective To study the effects of Yunnan BaiYao on the expressions of c-fos and c-jun mRNA in HPDLFs and explore the potential mechanism that Yunnan BaiYao promotes the proliferation and differentiation of HPDLFs．Methods The HPDLFs tissue was obtained from the extracted healthy premolar．The HPDLFs used underwent four to six passages．Cells were divided into untreated group， positive control group and treated group. In treated group，HPDLFs were co-cultured with Yunnan BaiYao solution for 4h with gradient concentration. The expressions of c-fos and c-jun mRNA were determined by RT-PCR．Results The results showed that the expressions of c-fos and c-jun mRNA were up-regulated significantly in treated group compared with control group（P＜0.05）．Conclusion Yunnna BaiYao can upregulate the expressions of c-fos and C-jun mRNA in HPDLFs. Through upregulating the expressions of c-fos and c-jun mRNA in hPDLs，Yunnan BaiYao can promote proliferation and differentiation of ossification of HPDLFs to induce bone formation.
2016, 37(09)
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［Abstract］Objective To investigate the relationship between the bacterial vaginosis and 8 putative periodontal pathogen infection．Methods A total of 48 patients with bacterial vaginosis were collected and 47 healthy female patients were selectedin the control group. Vaginal secretion and subgingival plaque were obtained from the study group and the control group. The presence of Porphyromonasgingivalis（P.g）， Tannerella forsythia（T.f），Treponemas denticola（T.d），Prevotell intermedia （P.i），Prevotella nigrescen （P.n），Peptostreptococcus micros（P.m），Fusobacterium nucleatum（F.n）and Campylobacter rectas （C.r）was detected by DNA extraction and PCR method. Simultaneously，all the patients underwent a clinical periodontal examination of the teeth in community periodontal index， including plaque index（PLI），bleeding on probing （BOP），probing depth （PD） and clinical attachment loss（CAL）．Results The prevalence of periodontal disease， PLI， BOP and CAL in the study group was significantly higher than in the control group（P＜0.05） and the PD had no statistically significant difference between the 2 groups（P＞0.05）.The 2 groups were both detected 8 putative periodontal pathogens in the vaginal secretion and the subgingival plaque samples. The detection ratio of T.dfrom both the vaginal secretion and subgingival plaque samples was significantly higher in the study group than that in the control group（P＜0.05）， and other 7 pathogens showed no statistically significant difference（P＞0.05）.Conclusion The prevalence of periodontal disease was higher among the bacterial vaginosis patients. The 8 putative periodontal pathogens were normal flora in the subgingival plaque and vaginal secretion.Td might be relevant to the pathogenesis of bacterial vaginosis.
［Abstract］Objective To investigate the relationship between the bacterial vaginosis and 8 putative periodontal pathogen infection．Methods A total of 48 patients with bacterial vaginosis were collected and 47 healthy female patients were selectedin the control group. Vaginal secretion and subgingival plaque were obtained from the study group and the control group. The presence of Porphyromonasgingivalis（P.g）， Tannerella forsythia（T.f），Treponemas denticola（T.d），Prevotell intermedia （P.i），Prevotella nigrescen （P.n），Peptostreptococcus micros（P.m），Fusobacterium nucleatum（F.n）and Campylobacter rectas （C.r）was detected by DNA extraction and PCR method. Simultaneously，all the patients underwent a clinical periodontal examination of the teeth in community periodontal index， including plaque index（PLI），bleeding on probing （BOP），probing depth （PD） and clinical attachment loss（CAL）．Results The prevalence of periodontal disease， PLI， BOP and CAL in the study group was significantly higher than in the control group（P＜0.05） and the PD had no statistically significant difference between the 2 groups（P＞0.05）.The 2 groups were both detected 8 putative periodontal pathogens in the vaginal secretion and the subgingival plaque samples. The detection ratio of T.dfrom both the vaginal secretion and subgingival plaque samples was significantly higher in the study group than that in the control group（P＜0.05）， and other 7 pathogens showed no statistically significant difference（P＞0.05）.Conclusion The prevalence of periodontal disease was higher among the bacterial vaginosis patients. The 8 putative periodontal pathogens were normal flora in the subgingival plaque and vaginal secretion.Td might be relevant to the pathogenesis of bacterial vaginosis.
2016, 37(09)
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［Abstract］Objective To research the relationship between quality of life among the elderly with chronic periodontitis（CP）and the severity of CP．Methods A total of 471 elderly patients seeking treatment in the affiliated Stomatology Hospital of Kunming Medical University from September 2013 to January 2014 and their companions were investigated using the questionnaire according to the Chinese version of the Oral health Impact Profile-14.Those who diagnosed with CP were separated into two groups according to Community periodontal index（CPI） through periodontal examination. Group A was diagnosed with the early CP， and Group B was diagnosed with the late CP. Database was established by Epidata and statistical analysis was performed by SPSS. Results A total of 237 elderly patients with early CP and 139 with late CP were recorded. The mean OHIP-14 scores of the former were 14.36±6.67，and the score of the later were 15.65±7.12 relatively. The two groups who lived through negative effects were compared. The results suggested in the 14 items of OHIP-14. The statistical significance existed in the following 4 items，“obvious pain appeared”，“uncomfortable when eating anything"， "unsatisfied with own diet”，“become easy to lose one's temper to others”（P＜0.05）. Conclusion OHR-QOL of elderly patients with the late CP is lower than that of those with the early CP.
［Abstract］Objective To research the relationship between quality of life among the elderly with chronic periodontitis（CP）and the severity of CP．Methods A total of 471 elderly patients seeking treatment in the affiliated Stomatology Hospital of Kunming Medical University from September 2013 to January 2014 and their companions were investigated using the questionnaire according to the Chinese version of the Oral health Impact Profile-14.Those who diagnosed with CP were separated into two groups according to Community periodontal index（CPI） through periodontal examination. Group A was diagnosed with the early CP， and Group B was diagnosed with the late CP. Database was established by Epidata and statistical analysis was performed by SPSS. Results A total of 237 elderly patients with early CP and 139 with late CP were recorded. The mean OHIP-14 scores of the former were 14.36±6.67，and the score of the later were 15.65±7.12 relatively. The two groups who lived through negative effects were compared. The results suggested in the 14 items of OHIP-14. The statistical significance existed in the following 4 items，“obvious pain appeared”，“uncomfortable when eating anything"， "unsatisfied with own diet”，“become easy to lose one's temper to others”（P＜0.05）. Conclusion OHR-QOL of elderly patients with the late CP is lower than that of those with the early CP.
2016, 37(09)
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［Abstract］Objective To provide guidance for oral health prevention by investigating oral health status of 480 Lahu people．Methods Oral health status of 480 Lahu people were investigated by trained dental therapists using standard diagnostic criteria and record. Participants were divided into 4 groups according to their age. Results The Lahu People in Linxiang county suffered from severe dental caries and periodontal disease. The caries prevalence rate among children of 5 years old was 78.3%. The rate of calculus among the children of 12 years old was 75%. The prevalence rates of caries and periodontal pockets were 91.7% and 43.3% among the adults between 35 and 44 years old. The above data were significantly higher than the results of the Third National Oral Health Survey. The rates of gingival bleeding and periodontal pocket were 51.7% and 49.2% among the aged from 65 to 74 years old， which were lower than that of the Third National Oral Health Survey. Among the participants，76% never brushed teeth and 85% brushed teeth only once a day in people who brushed teeth regularly. Conclusion Poor status and maintenance of oral health in the Lahu People suggest that education and resources for oral health should be invested.
［Abstract］Objective To provide guidance for oral health prevention by investigating oral health status of 480 Lahu people．Methods Oral health status of 480 Lahu people were investigated by trained dental therapists using standard diagnostic criteria and record. Participants were divided into 4 groups according to their age. Results The Lahu People in Linxiang county suffered from severe dental caries and periodontal disease. The caries prevalence rate among children of 5 years old was 78.3%. The rate of calculus among the children of 12 years old was 75%. The prevalence rates of caries and periodontal pockets were 91.7% and 43.3% among the adults between 35 and 44 years old. The above data were significantly higher than the results of the Third National Oral Health Survey. The rates of gingival bleeding and periodontal pocket were 51.7% and 49.2% among the aged from 65 to 74 years old， which were lower than that of the Third National Oral Health Survey. Among the participants，76% never brushed teeth and 85% brushed teeth only once a day in people who brushed teeth regularly. Conclusion Poor status and maintenance of oral health in the Lahu People suggest that education and resources for oral health should be invested.
2016, 37(09)
Abstract:
［Abstract］Objective To analyze the effects of self-ligating bracket on enlarging the maxillary alveolar arch and to investigate the the non-extraction treatment programs. Methods All patients were used heat activated basic and precise theory for the orthodontist in order to make a plan fordeveloping nickel-titanium wire， then assessed by occlusalplane analysis method. The maxillary model andcephalometric radiographs were collected and measured before the treatment. The data of the resultswereanalyzed．Results After the treatment， the increase of the width of the dental arch was related to the ∠FMA， crowding degree and canines initial position. The increase of arch length was related to the ∠ANB， crowding degree，malocclusion classification， canines initial position andthe second molar eruption．Conclusion The essential factors include the crowding degree of arch， ∠FMA， ∠ANB， the angle of the anterior teeth，malocclusion classification，canines initial position andthe second molar eruptioncan affect the result of non-extraction quick self-ligating bracket appliance treatment on enlarging the maxillary alveolar.
［Abstract］Objective To analyze the effects of self-ligating bracket on enlarging the maxillary alveolar arch and to investigate the the non-extraction treatment programs. Methods All patients were used heat activated basic and precise theory for the orthodontist in order to make a plan fordeveloping nickel-titanium wire， then assessed by occlusalplane analysis method. The maxillary model andcephalometric radiographs were collected and measured before the treatment. The data of the resultswereanalyzed．Results After the treatment， the increase of the width of the dental arch was related to the ∠FMA， crowding degree and canines initial position. The increase of arch length was related to the ∠ANB， crowding degree，malocclusion classification， canines initial position andthe second molar eruption．Conclusion The essential factors include the crowding degree of arch， ∠FMA， ∠ANB， the angle of the anterior teeth，malocclusion classification，canines initial position andthe second molar eruptioncan affect the result of non-extraction quick self-ligating bracket appliance treatment on enlarging the maxillary alveolar.
2016, 37(09)
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［Abstract］Objective To provide safety reference for the development of anti-cancer drugs by evaluating thetoxicological safety of the anticancer bioactive fraction AMH-T of lichen through the understanding of its poisonous nature and the intensity. Methods Acute toxicity test， bone marrow micronucleus test in mice，sperm malformation test in rats， Ames test and short-term repeat drug test in mice were conducted. Results Male mice were injected LD50 of 147 mg/kg and female mice 171 mg/kg. Conclusion Injection of AMH-T has acute toxicity and liver toxicity，but has no genetic toxicity.
［Abstract］Objective To provide safety reference for the development of anti-cancer drugs by evaluating thetoxicological safety of the anticancer bioactive fraction AMH-T of lichen through the understanding of its poisonous nature and the intensity. Methods Acute toxicity test， bone marrow micronucleus test in mice，sperm malformation test in rats， Ames test and short-term repeat drug test in mice were conducted. Results Male mice were injected LD50 of 147 mg/kg and female mice 171 mg/kg. Conclusion Injection of AMH-T has acute toxicity and liver toxicity，but has no genetic toxicity.
2016, 37(09)
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［Abstract］Objective To investigate the gene expression change of TNF-α， IL-6 and IL-1β at different time points in brain tissues of rats with cerebral ischemia reperfusion injury. Methods A total of 24 adult male SD rats were randomly divided into four groups: sham group and 3 groups with brain ischemia reperfusion of 3h， 6h and 12h. Real-Time PCR was used to analyze the gene expression of TNF-α， IL-6 and IL-1β at 3h， 6h， and 12h after reperfusion. Results In the sham group， the mRNA expression levels of TNF-α， IL-6 and IL-1βin were low， but increased immediately after brain ischemia injury and decreased gradually thereafter. The gene expression of TNF-α mRNA at 3h after reperfusion was significantly increased and reached the peak （P＜0.01） then significantly decreased at 12h after reperfusion. The gene expression of IL-6 mRNA was notably increased at 3h after reperfusion and peaked at 6h （P＜0.01）， and significantly decreased at 12h compared with 6h （P＜0.01）. The gene expression of IL-1βmRNA at 3h after reperfusion was significantly increased， peaked at 6h （P＜0.01） and significantly decreased at 12h （P＜0.01）. Conclusion The gene expression levels of TNF-α， IL-6 and IL-1β mRNA increased significantly in the early stage of reperfusion and decreased gradually after reaching the peak， which suggested that the gene expression change of TNF-α，IL-6 and IL-1β was involved in the mechanism of cerebral ischemia reperfusion injury.
［Abstract］Objective To investigate the gene expression change of TNF-α， IL-6 and IL-1β at different time points in brain tissues of rats with cerebral ischemia reperfusion injury. Methods A total of 24 adult male SD rats were randomly divided into four groups: sham group and 3 groups with brain ischemia reperfusion of 3h， 6h and 12h. Real-Time PCR was used to analyze the gene expression of TNF-α， IL-6 and IL-1β at 3h， 6h， and 12h after reperfusion. Results In the sham group， the mRNA expression levels of TNF-α， IL-6 and IL-1βin were low， but increased immediately after brain ischemia injury and decreased gradually thereafter. The gene expression of TNF-α mRNA at 3h after reperfusion was significantly increased and reached the peak （P＜0.01） then significantly decreased at 12h after reperfusion. The gene expression of IL-6 mRNA was notably increased at 3h after reperfusion and peaked at 6h （P＜0.01）， and significantly decreased at 12h compared with 6h （P＜0.01）. The gene expression of IL-1βmRNA at 3h after reperfusion was significantly increased， peaked at 6h （P＜0.01） and significantly decreased at 12h （P＜0.01）. Conclusion The gene expression levels of TNF-α， IL-6 and IL-1β mRNA increased significantly in the early stage of reperfusion and decreased gradually after reaching the peak， which suggested that the gene expression change of TNF-α，IL-6 and IL-1β was involved in the mechanism of cerebral ischemia reperfusion injury.
2016, 37(09)
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［Abstract］Objective To study the effect of DNA methylation regulation on the toxic effect of paraquat on the sensitized V79 cells t pretreated with 5-aza-2'-deoxycytidine. Methods V79 cells were treated by 5-aza-2'-deoxycytidine （5-Aza-2'-dc） for 12h， which is a DNA methylation inhibitor，and then treated with paraquat for 12h. The morphological changes of V79 cells were observed by microscopy and the cell viability was determined by MTT assay and trypan blue staining method．Results Microscopic examination showed that the combination of 5-Aza-2'-dc and paraquat had stronger effect in inhibiting the growth of V79 cells(the cells became smaller and poorer adhensive ability ) than single 5-Aza-2'-dc or paraquat. MTT assay showed that cell viability in the combination group （54.47±3.04）% was significantly lower than the 5-Aza-2'-dc group（95.52 ± 0.90）% and paraquat group（89.68±4.26）% （P＜0.05）. Trypan blue staining assay showed that the death rate of cells in the combination group（53.58±1.57）% was significantly higher than the 5-Aza-2'-dc group（7.44 ± 2.31）% and paraquat group（12.90±1.21）%（P＜0.05）. Conclusion 5-Aza-2'-dc promotes V79 cells damage caused by paraquat.
［Abstract］Objective To study the effect of DNA methylation regulation on the toxic effect of paraquat on the sensitized V79 cells t pretreated with 5-aza-2'-deoxycytidine. Methods V79 cells were treated by 5-aza-2'-deoxycytidine （5-Aza-2'-dc） for 12h， which is a DNA methylation inhibitor，and then treated with paraquat for 12h. The morphological changes of V79 cells were observed by microscopy and the cell viability was determined by MTT assay and trypan blue staining method．Results Microscopic examination showed that the combination of 5-Aza-2'-dc and paraquat had stronger effect in inhibiting the growth of V79 cells(the cells became smaller and poorer adhensive ability ) than single 5-Aza-2'-dc or paraquat. MTT assay showed that cell viability in the combination group （54.47±3.04）% was significantly lower than the 5-Aza-2'-dc group（95.52 ± 0.90）% and paraquat group（89.68±4.26）% （P＜0.05）. Trypan blue staining assay showed that the death rate of cells in the combination group（53.58±1.57）% was significantly higher than the 5-Aza-2'-dc group（7.44 ± 2.31）% and paraquat group（12.90±1.21）%（P＜0.05）. Conclusion 5-Aza-2'-dc promotes V79 cells damage caused by paraquat.
2016, 37(09)
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［Abstract］Objective To explore species specificity of 29 Y-SNP loci and to lay the foundation for forensic application. Methods Human DNA and 8 different kinds of common animals' DNA were amplified separately by PCR. The PCR products were analyzed with PAGE. Results Twenty-three out of 29 Y-SNP loci were only amplified by the male human DNA， which indicated a good species specificity. Three loci amplified from human and some animals showed that the length of the product was different between two species. Another three loci amplified from human and animal showed that the length of the fragment was similar between human and animal. Five loci were amplified by PCR products from both male and female samples. Conclusion Most of 29 Y-SNP loci， amplified in male humans， have good species specificity and can be directly used for personal identification and paternity testing.
［Abstract］Objective To explore species specificity of 29 Y-SNP loci and to lay the foundation for forensic application. Methods Human DNA and 8 different kinds of common animals' DNA were amplified separately by PCR. The PCR products were analyzed with PAGE. Results Twenty-three out of 29 Y-SNP loci were only amplified by the male human DNA， which indicated a good species specificity. Three loci amplified from human and some animals showed that the length of the product was different between two species. Another three loci amplified from human and animal showed that the length of the fragment was similar between human and animal. Five loci were amplified by PCR products from both male and female samples. Conclusion Most of 29 Y-SNP loci， amplified in male humans， have good species specificity and can be directly used for personal identification and paternity testing.
2016, 37(09)
Abstract:
［Abstract］Objective To investigate the characteristics of diet for infants in relatively poor counties in different cities of Yunnan and to provide a reference for carrying out educational consultation in the future by comparing and analyzing the data of infant diet in those areas. Methods Based on the GDP and habits of diet， the characteristics of infants' diet was investigated and analyzed in four counties including Yiliang in Zhaotong， Jianchuan in Dali， Lushui in Nujiang， and Mojiang in Puer， with low income and different habits of diet. Results No difference was found among people who fed the infants in terms of sex， age groups， feeding relationship and degree of education except for one fact that the feeding rate of parents in Jianchuan county was lower than that in Yiliang county. Based on the standard intake of nutrient in Chinese people， the intake of infant protein in 6-12 months achieved Chinese standard in four counties. Energy， fat and carbohydrates were lower than the standard （P＜0.05）. Apart from the fact that energy， protein， fat and carbohydrates were lower in Yiliang county， no significant difference was found among four counties. The intake of protein and carbohydrates for infants in 13-24 months achieved Chinese standard in the four counties， but energy and fat were lower than the standard. The carbohydrates of infants in 6-24 months was normal and the fat was lower compared with acceptable macro nutrient distribution ranges. The intake of carbohydrates， fat and protein were similar among four counties. Conclusion The diet composition and the nutrient condition for infants are poor in four counties. Health education of nutrition for infants is needed in those areas.
［Abstract］Objective To investigate the characteristics of diet for infants in relatively poor counties in different cities of Yunnan and to provide a reference for carrying out educational consultation in the future by comparing and analyzing the data of infant diet in those areas. Methods Based on the GDP and habits of diet， the characteristics of infants' diet was investigated and analyzed in four counties including Yiliang in Zhaotong， Jianchuan in Dali， Lushui in Nujiang， and Mojiang in Puer， with low income and different habits of diet. Results No difference was found among people who fed the infants in terms of sex， age groups， feeding relationship and degree of education except for one fact that the feeding rate of parents in Jianchuan county was lower than that in Yiliang county. Based on the standard intake of nutrient in Chinese people， the intake of infant protein in 6-12 months achieved Chinese standard in four counties. Energy， fat and carbohydrates were lower than the standard （P＜0.05）. Apart from the fact that energy， protein， fat and carbohydrates were lower in Yiliang county， no significant difference was found among four counties. The intake of protein and carbohydrates for infants in 13-24 months achieved Chinese standard in the four counties， but energy and fat were lower than the standard. The carbohydrates of infants in 6-24 months was normal and the fat was lower compared with acceptable macro nutrient distribution ranges. The intake of carbohydrates， fat and protein were similar among four counties. Conclusion The diet composition and the nutrient condition for infants are poor in four counties. Health education of nutrition for infants is needed in those areas.
2016, 37(09)
Abstract:
［Abstract］Objective To determine the prevalence of fatigue among taxi drivers in Kunming city， to better understand their general working and health conditions，and to determine the risk factors associated with fatigued driving．Methods A total of 400 taxi drivers were randomly selected for participation in a self-administered questionnaire survey， which included height and weight measurements. The response rate was 88.3%. The survey consisted of four main categories: personal particulars，social habits，work patterns and sleep profile. The Epworth Sleepiness Scale was used to estimate the level of daytime sleepiness and fatigue. Multiple logistic regression analysis was used to estimate the adjusted odd ratios and 95% confidence interval associated with risk factors related to fatigue among taxi drivers. Results A high proportion of taxi drivers were obese and had self-reported hypertension， diabetes mellitus and high cholesterol. Driver fatigue was associated with very poor/poor self-rating of quality of sleep，having an additional part-time job，and driving more than 10 hours a day. Conclusion The findings of the present study will improve awareness of the work and health conditions of taxi drivers，and contribute toward efforts to achieve a healthier workforce. A lower prevalence of fatigued driving may lead to lower risks of road traffic accidents，lower economic loss，higher productivity，and safer roads for all.
［Abstract］Objective To determine the prevalence of fatigue among taxi drivers in Kunming city， to better understand their general working and health conditions，and to determine the risk factors associated with fatigued driving．Methods A total of 400 taxi drivers were randomly selected for participation in a self-administered questionnaire survey， which included height and weight measurements. The response rate was 88.3%. The survey consisted of four main categories: personal particulars，social habits，work patterns and sleep profile. The Epworth Sleepiness Scale was used to estimate the level of daytime sleepiness and fatigue. Multiple logistic regression analysis was used to estimate the adjusted odd ratios and 95% confidence interval associated with risk factors related to fatigue among taxi drivers. Results A high proportion of taxi drivers were obese and had self-reported hypertension， diabetes mellitus and high cholesterol. Driver fatigue was associated with very poor/poor self-rating of quality of sleep，having an additional part-time job，and driving more than 10 hours a day. Conclusion The findings of the present study will improve awareness of the work and health conditions of taxi drivers，and contribute toward efforts to achieve a healthier workforce. A lower prevalence of fatigued driving may lead to lower risks of road traffic accidents，lower economic loss，higher productivity，and safer roads for all.
2016, 37(09)
Abstract:
［Abstract］Objective To provide useful information on reducing risky drinking for the Dept. of Public Health taking a county in Yunnan province as an example to explore the risk factors related to risky drinking. Methods A total of 574 participants identified as Miao，Yi and Han People at or older than 12 years old，who had been living there for 6 months or more were selected and surveyed in 5 townships in the county through stratified sampling. Alcohol consumption was collected using the beverage-specific quantity frequency (BSQF) method and analyzed using binary logistic regression and chi-square test. Results The number of drinkers in the family, undesirable drinking environment among friends and enculturation (β＝0.073) could increase the likelihood of risky drinking. Risky drinking pattern was positively associated with age (β＝1.006), and negatively associated with gender (β＝-2.947) and awareness of risky drinking among rural residents. Conclusion The important measures to control risky drinking behavior in terms of health promotion and education include reducing the number of drinkers in the family, and preventing from undesirable drinking environment among friends and harmful drinking culture. These measures are crucial to prevent early onset of alcohol drinking among teenagers and to reduce risky drinking among middle aged and aged population.
［Abstract］Objective To provide useful information on reducing risky drinking for the Dept. of Public Health taking a county in Yunnan province as an example to explore the risk factors related to risky drinking. Methods A total of 574 participants identified as Miao，Yi and Han People at or older than 12 years old，who had been living there for 6 months or more were selected and surveyed in 5 townships in the county through stratified sampling. Alcohol consumption was collected using the beverage-specific quantity frequency (BSQF) method and analyzed using binary logistic regression and chi-square test. Results The number of drinkers in the family, undesirable drinking environment among friends and enculturation (β＝0.073) could increase the likelihood of risky drinking. Risky drinking pattern was positively associated with age (β＝1.006), and negatively associated with gender (β＝-2.947) and awareness of risky drinking among rural residents. Conclusion The important measures to control risky drinking behavior in terms of health promotion and education include reducing the number of drinkers in the family, and preventing from undesirable drinking environment among friends and harmful drinking culture. These measures are crucial to prevent early onset of alcohol drinking among teenagers and to reduce risky drinking among middle aged and aged population.
2016, 37(09)
Abstract:
［Abstract］Objective To study and observe the change of nerve function and erythrocyte immune indexes of patients with severe craniocerebral injury during the perioperative period. Methods Forty patients with severe craniocerebral injury treated with surgery in our hospital from July 2013 to August 2015 were selected as the observation group and 40 healthy persons with the same ages in the same period were selected as the control group. The nerve function related indexes and erythrocyte immune indexes of observation group before and at first，third，fifth，seventh，tenth and fourteenth day after the surgery and those of control group were compared. Results The serum nerve function related indexes of observation group before and at first，third，fifth，seventh，tenth and fourteenth day after the surgery were higher than those of control group. The erythrocyte immune indexes of observation group before and at first，third，fifth，seventh and tenth day after the surgery were worse than those of control group. The erythrocyte immune indexes at fifth and seventh day after the surgery were worse than those before and at first，third，third，tenth and fourteenth day after the surgery. The differences of comparison indexes were all significant（P＜0.05）. Conclusion The change of nerve function and erythrocyte immune indexes of patients with severe craniocerebral injury during the perioperative period are obvious. Those indexes should be paid with enough monitoring and intervention.
［Abstract］Objective To study and observe the change of nerve function and erythrocyte immune indexes of patients with severe craniocerebral injury during the perioperative period. Methods Forty patients with severe craniocerebral injury treated with surgery in our hospital from July 2013 to August 2015 were selected as the observation group and 40 healthy persons with the same ages in the same period were selected as the control group. The nerve function related indexes and erythrocyte immune indexes of observation group before and at first，third，fifth，seventh，tenth and fourteenth day after the surgery and those of control group were compared. Results The serum nerve function related indexes of observation group before and at first，third，fifth，seventh，tenth and fourteenth day after the surgery were higher than those of control group. The erythrocyte immune indexes of observation group before and at first，third，fifth，seventh and tenth day after the surgery were worse than those of control group. The erythrocyte immune indexes at fifth and seventh day after the surgery were worse than those before and at first，third，third，tenth and fourteenth day after the surgery. The differences of comparison indexes were all significant（P＜0.05）. Conclusion The change of nerve function and erythrocyte immune indexes of patients with severe craniocerebral injury during the perioperative period are obvious. Those indexes should be paid with enough monitoring and intervention.
2016, 37(09)
Abstract:
［Abstract］Objective To compare the difference of IL-8 and MMP-9 levels in the serum and sputum before and after treatment in patients with acute exacerbations of COPD， and to analyze the correlation between IL-8 and MMP-9 levels and lung function. Method A total of 20 cases of AECOPD patients were randomly selected in the observation group and 15 cases of healthy people were selected in the control group. Pulmonary function was measured and the specimens of sputum and blood were collected during the admission and discharge for AECOPD patients. FEV1 and FEV1/FVC% were recorded，and the concentration of IL-8 and MMP-9 in the sputum supernatant and serum were tested with double antibody sandwich enzyme linked immunosorbent assay before and after treatment. All the data and correlation were analyzed with t test and SPSS software. Results（1）Before the treatment，serum IL-8 concentration in COPD patients was 28.30±14.39 pg/mL， higher than that in the control group［17.46±3.48）pg/mL，P＝0.008］. After treatment， the serum IL-8 concentration was significantly decreased ［（13.30±6.31）pg/mL，P＝0.000］. IL-8 concentration of sputum significantly decreased after treatment［（501.60± 508.61）pg/mL，P＝0.042］than one before treatment（639.40±703.12）pg/mL. （2） Before treatment， serum MMP-9 concentration in patients with AECOPD was 1.12 ±0.36 ng/mL， lower than control group［（17.89±11.00）ng/mL，P＝0.000）］. After treatment， the serum MMP-9 concentration was significantly decreased［（0.87±0.31）ng/mL，P＝0.000］. MMP-9 concentration of sputum before treatment（12.04±12.22）ng/mL decreased significantly after treatment ［（8.02±7.13）ng/mL，P＝0.005］.（3）Before treatment， no correlation was seen between the concentration of serum IL-8 and FEV1， FEV1/FVC. Negative correlation was observed between the sputum IL-8 concentration and FEV1/FVC and no correlation was found with FEV1. After treatment，we found that no correlation showed between the concentration of IL-8 and FEV1， FEV1/FVC， and negative correlation was seen between the IL-8 concentration in sputum and FEV1， FEV1/FVC. （4）Before treatment，no correlation between the concentration of serum MMP-9 and FEV1， FEV1/FVC was observed and no correlation between the sputum MMP-9 concentration with FEV1 was seen. Negatively correlation was found between the sputum MMP-9 level wtih FEV1/FVC. After treatment， we observed no correlation between the serum concentration of MMP-9 and FEV1， FEV1/FVC， and negative correlation between the concentration of MMP-9 in sputum and FEV1，FEV1/FVC. Conclusion The concentration of IL-8 and MMP-9 in serum and sputum in patients with acute exacerbation of COPD is higher than those in the stable phase. IL-8 and MMP-9 levels in serum show no correlation with lung function. Negative correlation was observed between IL-8 and MMP-9 levels in sputum and lung function. We can test the levels of IL-8 and MMP-9 in sputum to evaluate the severity of the disease.
［Abstract］Objective To compare the difference of IL-8 and MMP-9 levels in the serum and sputum before and after treatment in patients with acute exacerbations of COPD， and to analyze the correlation between IL-8 and MMP-9 levels and lung function. Method A total of 20 cases of AECOPD patients were randomly selected in the observation group and 15 cases of healthy people were selected in the control group. Pulmonary function was measured and the specimens of sputum and blood were collected during the admission and discharge for AECOPD patients. FEV1 and FEV1/FVC% were recorded，and the concentration of IL-8 and MMP-9 in the sputum supernatant and serum were tested with double antibody sandwich enzyme linked immunosorbent assay before and after treatment. All the data and correlation were analyzed with t test and SPSS software. Results（1）Before the treatment，serum IL-8 concentration in COPD patients was 28.30±14.39 pg/mL， higher than that in the control group［17.46±3.48）pg/mL，P＝0.008］. After treatment， the serum IL-8 concentration was significantly decreased ［（13.30±6.31）pg/mL，P＝0.000］. IL-8 concentration of sputum significantly decreased after treatment［（501.60± 508.61）pg/mL，P＝0.042］than one before treatment（639.40±703.12）pg/mL. （2） Before treatment， serum MMP-9 concentration in patients with AECOPD was 1.12 ±0.36 ng/mL， lower than control group［（17.89±11.00）ng/mL，P＝0.000）］. After treatment， the serum MMP-9 concentration was significantly decreased［（0.87±0.31）ng/mL，P＝0.000］. MMP-9 concentration of sputum before treatment（12.04±12.22）ng/mL decreased significantly after treatment ［（8.02±7.13）ng/mL，P＝0.005］.（3）Before treatment， no correlation was seen between the concentration of serum IL-8 and FEV1， FEV1/FVC. Negative correlation was observed between the sputum IL-8 concentration and FEV1/FVC and no correlation was found with FEV1. After treatment，we found that no correlation showed between the concentration of IL-8 and FEV1， FEV1/FVC， and negative correlation was seen between the IL-8 concentration in sputum and FEV1， FEV1/FVC. （4）Before treatment，no correlation between the concentration of serum MMP-9 and FEV1， FEV1/FVC was observed and no correlation between the sputum MMP-9 concentration with FEV1 was seen. Negatively correlation was found between the sputum MMP-9 level wtih FEV1/FVC. After treatment， we observed no correlation between the serum concentration of MMP-9 and FEV1， FEV1/FVC， and negative correlation between the concentration of MMP-9 in sputum and FEV1，FEV1/FVC. Conclusion The concentration of IL-8 and MMP-9 in serum and sputum in patients with acute exacerbation of COPD is higher than those in the stable phase. IL-8 and MMP-9 levels in serum show no correlation with lung function. Negative correlation was observed between IL-8 and MMP-9 levels in sputum and lung function. We can test the levels of IL-8 and MMP-9 in sputum to evaluate the severity of the disease.
2016, 37(09)
Abstract:
［Abstract］Objective To observe the clinical efficacy of magnesium sulfate inhalation combined with budesonide and terbutaline sulfate nebulizer for the treatment of bronchiolitis. Methods Sixty children with bronchiolitis were randomly divided into observation group and control group with 30 cases in each group. Children in the control group received routine treatment and the observation group were inhaled with magnesium sulfate combining budesonide and terbutaline sulfate. Curative effects were evaluated in the aspects of the clinical symptoms，serum inflammatory factors and overall clinical efficacy. Results The symptoms in children including asthma，shortness of breath， coughing， wheezing and lung auscultation were significantly alleviated within a shorter period of time than that in the control group（P＜0.05）. The serum levels of TNF-ɑ，IL-6，IL-8 and TIgE were significantly reduced in both groups after the treatment（P＜0.05）. But in the observation group， the alleviation of the symptoms was significantly greater than that in the control group（P＜0.05）. The overall effective rate in the observation group and the control group was 93.3% and 70.0% respectively （P＜0.001）. Conclusion The clinical efficacy of inhaling magnesium sulfate with budesonide and terbutaline sulfate to treat bronchiolitis is satisfactory and worth clinical application.
［Abstract］Objective To observe the clinical efficacy of magnesium sulfate inhalation combined with budesonide and terbutaline sulfate nebulizer for the treatment of bronchiolitis. Methods Sixty children with bronchiolitis were randomly divided into observation group and control group with 30 cases in each group. Children in the control group received routine treatment and the observation group were inhaled with magnesium sulfate combining budesonide and terbutaline sulfate. Curative effects were evaluated in the aspects of the clinical symptoms，serum inflammatory factors and overall clinical efficacy. Results The symptoms in children including asthma，shortness of breath， coughing， wheezing and lung auscultation were significantly alleviated within a shorter period of time than that in the control group（P＜0.05）. The serum levels of TNF-ɑ，IL-6，IL-8 and TIgE were significantly reduced in both groups after the treatment（P＜0.05）. But in the observation group， the alleviation of the symptoms was significantly greater than that in the control group（P＜0.05）. The overall effective rate in the observation group and the control group was 93.3% and 70.0% respectively （P＜0.001）. Conclusion The clinical efficacy of inhaling magnesium sulfate with budesonide and terbutaline sulfate to treat bronchiolitis is satisfactory and worth clinical application.
2016, 37(09)
Abstract:
［Abstract］Objective To investigate the clinical application effects of tracheal intubation under general anesthesia guiding by HC visual laryngoscope in combination with fiberoptic bronchoscopy via clinical studies. Methods A total of 348 patients underwent the tracheal intubation under general anesthesia in the hospital between January 2013 and January 2015 were randomly selected and Divided into three groups according to different ways of guiding tracheal intubation．The first group was a simple fiber light guide bronchoscopy to guide the general anesthesia tracheal intubation was set to F group,In the second group, the general anesthesia tracheal intubation was set to H group for the simple HC video．The third group was HC video mirror combined with fiber light guide bronchoscopy to guide the general anesthesia tracheal intubation was set to H+F group. The general condition and intubation conditions such as the time and frequencies of intubation in three groups were recorded respectively. Results The general condition，age，BMI index，thyromental distance， interincisor distance value were similar among three groups. The time needed for intubation was the longest in group F up to（41±11） s. The highest frequency of intubation was in group H with 30 times，and the time of glottis exposure was the longest in group F as（21±9）s. The difference among groups and intra-groups has statistical significance（P＜0.05）. Conclusion HC visual laryngoscope in combination with fiberoptic bronchoscopy guiding tracheal intubation under general anesthesia has a good effect in clinical practice，and is worthy of clinical promotion.
［Abstract］Objective To investigate the clinical application effects of tracheal intubation under general anesthesia guiding by HC visual laryngoscope in combination with fiberoptic bronchoscopy via clinical studies. Methods A total of 348 patients underwent the tracheal intubation under general anesthesia in the hospital between January 2013 and January 2015 were randomly selected and Divided into three groups according to different ways of guiding tracheal intubation．The first group was a simple fiber light guide bronchoscopy to guide the general anesthesia tracheal intubation was set to F group,In the second group, the general anesthesia tracheal intubation was set to H group for the simple HC video．The third group was HC video mirror combined with fiber light guide bronchoscopy to guide the general anesthesia tracheal intubation was set to H+F group. The general condition and intubation conditions such as the time and frequencies of intubation in three groups were recorded respectively. Results The general condition，age，BMI index，thyromental distance， interincisor distance value were similar among three groups. The time needed for intubation was the longest in group F up to（41±11） s. The highest frequency of intubation was in group H with 30 times，and the time of glottis exposure was the longest in group F as（21±9）s. The difference among groups and intra-groups has statistical significance（P＜0.05）. Conclusion HC visual laryngoscope in combination with fiberoptic bronchoscopy guiding tracheal intubation under general anesthesia has a good effect in clinical practice，and is worthy of clinical promotion.
2016, 37(09)
Abstract:
［Abstract］Objective To discuss the value of applying psychological therapy for patients with cerebral apoplexy in recovery. Methods In recent years， 65 patients with cerebral apoplexy admitted in our hospital were randomly selected and divided into observation group and control group. Patients in the control group only received the conventional treatment and those in the observation group received psychological treatment on the basis of the traditional therapy. Psychological characteristics， activity of daily living and the improvement of nerve function were compared between two groups before and after treatment. Results After treatment， mental improvement， FMA， MBI in the observation group were significantly better than those of control group（P＜0.05）. Conclusion To improve the prognosis of patients with cerebral apoplexy effect， physical and mental development should be equally emphasized. Psychological intervention has become a key for stroke rehabilitation treatment， which significantly improves the treatment compliance， rehabilitation and the quality of life in patients.
［Abstract］Objective To discuss the value of applying psychological therapy for patients with cerebral apoplexy in recovery. Methods In recent years， 65 patients with cerebral apoplexy admitted in our hospital were randomly selected and divided into observation group and control group. Patients in the control group only received the conventional treatment and those in the observation group received psychological treatment on the basis of the traditional therapy. Psychological characteristics， activity of daily living and the improvement of nerve function were compared between two groups before and after treatment. Results After treatment， mental improvement， FMA， MBI in the observation group were significantly better than those of control group（P＜0.05）. Conclusion To improve the prognosis of patients with cerebral apoplexy effect， physical and mental development should be equally emphasized. Psychological intervention has become a key for stroke rehabilitation treatment， which significantly improves the treatment compliance， rehabilitation and the quality of life in patients.
2016, 37(09)
Abstract:
［Abstract］Objective To analyze the therapeutic effect of acute stroke dysphagia using rehabilitation therapy. Methods A total of 94 cases diagnosed with dysphagia after acute stroke were randomly selected from January 2012 to May 2013 in our hospital. The patients were equally divided into control group and research group. The control group received the conventional support treatment and the research group received comprehensive rehabilitation treatment. The results of swallowing dysfunction recovery of two groups were compared. Results After the treatment for 3 weeks， swallowing disorder degree score and swallowing function ratings were improved in both groups and the research group's scores were significantly higher than those of the control group（P＜0.05）. Conclusion Application of comprehensive rehabilitation treatment for dysphagia in patients with acute stroke has significant curative effect and is worth promoting.
［Abstract］Objective To analyze the therapeutic effect of acute stroke dysphagia using rehabilitation therapy. Methods A total of 94 cases diagnosed with dysphagia after acute stroke were randomly selected from January 2012 to May 2013 in our hospital. The patients were equally divided into control group and research group. The control group received the conventional support treatment and the research group received comprehensive rehabilitation treatment. The results of swallowing dysfunction recovery of two groups were compared. Results After the treatment for 3 weeks， swallowing disorder degree score and swallowing function ratings were improved in both groups and the research group's scores were significantly higher than those of the control group（P＜0.05）. Conclusion Application of comprehensive rehabilitation treatment for dysphagia in patients with acute stroke has significant curative effect and is worth promoting.
2016, 37(09)
Abstract:
［Abstract］Objective To compare anesthetic effect and safety of general anesthesia and combined spinal and epidural anesthesia used in autonomic nervous hyperresponsive surgery for patients with paraplegia. Methods 26 paraplegic patients were randomly divided into two groups - control group and treatment group from February 2011 to November，2015，each with 13 cases. The control group used general anesthesia，while the treatment group used combined spinal and epidural anesthesia, to observe onset time, duration, intraoperative hemodynamic changes and complications, Complications, length of stay and cost，Days and costs of hospitalization，satisfaction of patients and their families，of anesthesia in two groups. Results The dosage of narcotics and the onset time of the treatment group were better than that of the control group．The difference between the two groups was significant，and had statistical significance（P＜0.05）．Two groups of patients after surgery，diastolic blood pressure，systolic blood pressure and heart rate were lower in the treatment group than in the control group，and had statistically significant difference（P＜0.05）；The postoperative complications of the treatment group were significantly better than those of the control group，and had statistically significant difference（P＜0.05）；There were statistically significant differences in postoperative pain degree between the two groups（P＜0.05）；Two groups of patients in hospital days，hospital costs，satisfaction rate had statistically significant difference，Have statistical significance（P＜0.05）. Conclusion In autonomic nervous hyperresponsive surgery for patients with paraplegia，anesthetic effect and safety of combined spinal and epidural anesthesia is significantly better than that of general anesthesia， featured by the rapid onset of action，long duration，fewer complications， strong safety and patients' great satisfaction. It is worth generalizing and applying clinically.
［Abstract］Objective To compare anesthetic effect and safety of general anesthesia and combined spinal and epidural anesthesia used in autonomic nervous hyperresponsive surgery for patients with paraplegia. Methods 26 paraplegic patients were randomly divided into two groups - control group and treatment group from February 2011 to November，2015，each with 13 cases. The control group used general anesthesia，while the treatment group used combined spinal and epidural anesthesia, to observe onset time, duration, intraoperative hemodynamic changes and complications, Complications, length of stay and cost，Days and costs of hospitalization，satisfaction of patients and their families，of anesthesia in two groups. Results The dosage of narcotics and the onset time of the treatment group were better than that of the control group．The difference between the two groups was significant，and had statistical significance（P＜0.05）．Two groups of patients after surgery，diastolic blood pressure，systolic blood pressure and heart rate were lower in the treatment group than in the control group，and had statistically significant difference（P＜0.05）；The postoperative complications of the treatment group were significantly better than those of the control group，and had statistically significant difference（P＜0.05）；There were statistically significant differences in postoperative pain degree between the two groups（P＜0.05）；Two groups of patients in hospital days，hospital costs，satisfaction rate had statistically significant difference，Have statistical significance（P＜0.05）. Conclusion In autonomic nervous hyperresponsive surgery for patients with paraplegia，anesthetic effect and safety of combined spinal and epidural anesthesia is significantly better than that of general anesthesia， featured by the rapid onset of action，long duration，fewer complications， strong safety and patients' great satisfaction. It is worth generalizing and applying clinically.
2016, 37(09)
Abstract:
［Abstract］Objective To compare the traditional electrophysiological testing with modified methods for differential diagnosis of Radial Tunnel Syndrome（RTS）. Methods A total of 87 selected patients were initially diagnosed as Lateral Epicondylitis（LE） or Tennis Elbow （TE） by doctors from the Outpatient Department of Orthopedics and Rehabilitation. Medical history was asked. Patients received physical examination and examinations for the sensory nerve action potential（SNAP） of superficial radial nerve， the compound muscle action potential（CMAP） of radial nerve and needle electromyography（EMG）to record the muscle Motor Unit Action Potentials（MUAPs）. Then， the modified methods for CMAP of radial nerve were conducted on the forearm in the neutral，pronation and supination positions. Three values of CMAP latency were compared. RTS was diagnosed when the difference value≥0.3 ms. The χ2 test was used to compare the positive detectable rates of the two methods for the RTS diagnosis. Results Thirteen out of 87 patients were diagnosed as RTS，among which three had interosseous nerve lesion and one had superficial radial nerve lesion. The traditional EMG failed to diagnose the remaining 9 RTS cases. These patients were finally diagnosed due to their latency difference of radial nerve CMAP ≥0.3ms when their forearms were examined in three positions. Conclusion The modified electrophysiology method shows a higher positive rate for the diagnosis of RTS. （P＜0.05）.
［Abstract］Objective To compare the traditional electrophysiological testing with modified methods for differential diagnosis of Radial Tunnel Syndrome（RTS）. Methods A total of 87 selected patients were initially diagnosed as Lateral Epicondylitis（LE） or Tennis Elbow （TE） by doctors from the Outpatient Department of Orthopedics and Rehabilitation. Medical history was asked. Patients received physical examination and examinations for the sensory nerve action potential（SNAP） of superficial radial nerve， the compound muscle action potential（CMAP） of radial nerve and needle electromyography（EMG）to record the muscle Motor Unit Action Potentials（MUAPs）. Then， the modified methods for CMAP of radial nerve were conducted on the forearm in the neutral，pronation and supination positions. Three values of CMAP latency were compared. RTS was diagnosed when the difference value≥0.3 ms. The χ2 test was used to compare the positive detectable rates of the two methods for the RTS diagnosis. Results Thirteen out of 87 patients were diagnosed as RTS，among which three had interosseous nerve lesion and one had superficial radial nerve lesion. The traditional EMG failed to diagnose the remaining 9 RTS cases. These patients were finally diagnosed due to their latency difference of radial nerve CMAP ≥0.3ms when their forearms were examined in three positions. Conclusion The modified electrophysiology method shows a higher positive rate for the diagnosis of RTS. （P＜0.05）.
2016, 37(09)
Abstract:
［Abstract］Objective To observe the clinical efficacy and adverse reactions between pemetrexed plus cisplatin and paclitaxel plus cisplatin in the treatment of advanced non-small cell lung cancer（NSCLC）. Methods Forty-two cases with non-small cell lung cancer in our hospital from June 2013 to June 2015 were selected. Patients were randomly divided into observation group and control group with 21 cases in each group. The observation group was treated with pemetrexed plus cisplatin and the control group was treated with paclitaxel plus cisplatin. The clinical efficacy and adverse reactions were observed after two courses （21 days of a course） and the statistical analysis was performed. Results In the observation group and control group， response rate and clinical benefit rate were 33.33%（7/21），28.57%（6/21）and 76.19%（16/21）， 71.43%（15/21） respectively. No statistical significance were seen between the two groups （P＞0.05）.The rate of hair loss （23.81%）（5/21）and the total number of adverse reactions（18.37%）（27/147）in the observation group were significantly lower than the rate of hair loss （47.62%）（10/21）and the total number of adverse reactions（25.17%）（37/147）in the control group（P＜0.05）. No statistical significance was found in the incidence rate of leukopenia，neutropenia， erythropenia，thrombocytopenia，nausea and vomiting and phlebitis between the two groups（P＞0.05）. Conclusion Pemetrexed plus cisplatin is as effective as paclitaxel plus cisplatin in the treatment of advanced NSCLC with less adverse reactions and is much safer than paclitaxel plus cisplatin. Pemetrexed plus cisplatin is more valuable in the clinical treatment of advanced NSCLC.
［Abstract］Objective To observe the clinical efficacy and adverse reactions between pemetrexed plus cisplatin and paclitaxel plus cisplatin in the treatment of advanced non-small cell lung cancer（NSCLC）. Methods Forty-two cases with non-small cell lung cancer in our hospital from June 2013 to June 2015 were selected. Patients were randomly divided into observation group and control group with 21 cases in each group. The observation group was treated with pemetrexed plus cisplatin and the control group was treated with paclitaxel plus cisplatin. The clinical efficacy and adverse reactions were observed after two courses （21 days of a course） and the statistical analysis was performed. Results In the observation group and control group， response rate and clinical benefit rate were 33.33%（7/21），28.57%（6/21）and 76.19%（16/21）， 71.43%（15/21） respectively. No statistical significance were seen between the two groups （P＞0.05）.The rate of hair loss （23.81%）（5/21）and the total number of adverse reactions（18.37%）（27/147）in the observation group were significantly lower than the rate of hair loss （47.62%）（10/21）and the total number of adverse reactions（25.17%）（37/147）in the control group（P＜0.05）. No statistical significance was found in the incidence rate of leukopenia，neutropenia， erythropenia，thrombocytopenia，nausea and vomiting and phlebitis between the two groups（P＞0.05）. Conclusion Pemetrexed plus cisplatin is as effective as paclitaxel plus cisplatin in the treatment of advanced NSCLC with less adverse reactions and is much safer than paclitaxel plus cisplatin. Pemetrexed plus cisplatin is more valuable in the clinical treatment of advanced NSCLC.
2016, 37(09)
Abstract:
［Abstract］Objective To study the serum levels of melatonin， tumor necrosis factor alpha（TNF-α）and interferon gamma（IFN-γ）in multiple sclerosis（MS） patients and the correlation with disability. Methods Forty patients with multiple sclerosis were collected as MS group and 30 healthy participants were collected as control group. Serum levels of melatonin and cytokines， including IFN-γ and TNF-， were detected in all participants by the enzyme-linked immunosorbent assay（ELISA）method; disability status of patients with MS was evaluated by EDSS scale. The relevant analysis between serum melatonin， TNF-α， IFN-γ levels and EDSS score in patients with MS was conducted. Results The concentration of serum melatonin in MS group was significantly lower than control group（P＜0.01）. TNF-α levels were higher than control group（P＜0.05）and the difference was statistically significant between MS patients and control group. Among MS group and control group， no significant correlation with the serum levels of IFN-γ was seen. The serum melatonin level was inversely correlated with EDSS score in MS patients（r = -0.76，P＜0.01），and positively correlated with TNF-α（r = 0.83，P＜0.01） and as compared to IFN-γ，no significant correlation was found （r = 0.17，P＞0.05）. Conclusion The decrease of melatonin and increase of TNF-α can be a factor in the inflammatory reaction in patients with MS，and is closely related with dysfunction occurring in multiple sclerosis. Serum melatonin and TNF-αcan be used as laboratory indicators to monitor clinical curative effect and evaluate prognosis of MS.
［Abstract］Objective To study the serum levels of melatonin， tumor necrosis factor alpha（TNF-α）and interferon gamma（IFN-γ）in multiple sclerosis（MS） patients and the correlation with disability. Methods Forty patients with multiple sclerosis were collected as MS group and 30 healthy participants were collected as control group. Serum levels of melatonin and cytokines， including IFN-γ and TNF-， were detected in all participants by the enzyme-linked immunosorbent assay（ELISA）method; disability status of patients with MS was evaluated by EDSS scale. The relevant analysis between serum melatonin， TNF-α， IFN-γ levels and EDSS score in patients with MS was conducted. Results The concentration of serum melatonin in MS group was significantly lower than control group（P＜0.01）. TNF-α levels were higher than control group（P＜0.05）and the difference was statistically significant between MS patients and control group. Among MS group and control group， no significant correlation with the serum levels of IFN-γ was seen. The serum melatonin level was inversely correlated with EDSS score in MS patients（r = -0.76，P＜0.01），and positively correlated with TNF-α（r = 0.83，P＜0.01） and as compared to IFN-γ，no significant correlation was found （r = 0.17，P＞0.05）. Conclusion The decrease of melatonin and increase of TNF-α can be a factor in the inflammatory reaction in patients with MS，and is closely related with dysfunction occurring in multiple sclerosis. Serum melatonin and TNF-αcan be used as laboratory indicators to monitor clinical curative effect and evaluate prognosis of MS.
2016, 37(09)
Abstract:
［Abstract］Objective To discuss whether it is necessary to integrate metabolic indices into diagnosis of polycystic ovary syndrome（PCOS）. Methods Taking ESHRE/ASRM diagnosis as the gold standard， 51 women with PCOS and 47 women without PCOS were selected and divided into the intervention group and control group respectively from the Department of Gynecology in the Second Affiliated Hospital of Kunming Medical University between January 2013 and July 2014. Logistic regression based on principal component analysis and significant variables chosen through single factor analysis were used to establish the new diagnostic model which combined reproductive indices and metabolic indices. We evaluated the validity and reliability of the new diagnostic model by using ROC curve analysis. Finally，we analyzed the consistence and difference between the new diagnostic model and the gold standard. Results Thirteen significant variables were chosen using single factor analysis. ROC analysis showed that an area under the curve was 0.976（P＜0.001） and the optimal cut-off point was 0.526 with a sensitivity of 96.08%， a specificity of 93.62% and a consistency of93.88%. The new diagnostic model had superior validity and reliability. The two diagnostic methods had strong consistence（Kappa=0.877，P＜0.001） and no difference （χ2＝0.167， P＝0.688）. Conclusion Considering that the integration of metabolic indices does not change the diagnosis result， we come to a conclusion that it is unnecessary to integrate metabolic indices into diagnosis of PCOS.
［Abstract］Objective To discuss whether it is necessary to integrate metabolic indices into diagnosis of polycystic ovary syndrome（PCOS）. Methods Taking ESHRE/ASRM diagnosis as the gold standard， 51 women with PCOS and 47 women without PCOS were selected and divided into the intervention group and control group respectively from the Department of Gynecology in the Second Affiliated Hospital of Kunming Medical University between January 2013 and July 2014. Logistic regression based on principal component analysis and significant variables chosen through single factor analysis were used to establish the new diagnostic model which combined reproductive indices and metabolic indices. We evaluated the validity and reliability of the new diagnostic model by using ROC curve analysis. Finally，we analyzed the consistence and difference between the new diagnostic model and the gold standard. Results Thirteen significant variables were chosen using single factor analysis. ROC analysis showed that an area under the curve was 0.976（P＜0.001） and the optimal cut-off point was 0.526 with a sensitivity of 96.08%， a specificity of 93.62% and a consistency of93.88%. The new diagnostic model had superior validity and reliability. The two diagnostic methods had strong consistence（Kappa=0.877，P＜0.001） and no difference （χ2＝0.167， P＝0.688）. Conclusion Considering that the integration of metabolic indices does not change the diagnosis result， we come to a conclusion that it is unnecessary to integrate metabolic indices into diagnosis of PCOS.
2016, 37(09)
Abstract:
［Abstract］Objective To evaluate the application value of time-intensity curve analysis of contrast- enhanced ultrasonography（CEUS） in differential diagnosis of malignant and benign breast masses. Methods From January 2015 to September 2015， 30 patients with one lesion confirmed by surgical pathology were examined by CEUS. Then time-intensity curve analysis was performed. Results 16 lesions were found in the benign group and 14 lesions were in the malignant group. Five parameters of benign and malignant group were statistically analyzed， including Perfusion slope rate（ C），intensity of peak（A），Subsidence slope rate （K）， time of peak value（T） and area under the curve（Area）. The perfusion slope rate（C） of benign and malignant group is [（0.24±0.41）vs（0.67±0.39）]. There was no statistical difference between the two groups in intensity of peak（A）， Subsidence slope rate （K）， time of peak value（T）and area under the curve（Area），except perfusion slope rate （P＜0.05） . Conclusion Time-intensity curve analysis of CEUS has certain effect on differential diagnosis of malignant and benign breast masses.
［Abstract］Objective To evaluate the application value of time-intensity curve analysis of contrast- enhanced ultrasonography（CEUS） in differential diagnosis of malignant and benign breast masses. Methods From January 2015 to September 2015， 30 patients with one lesion confirmed by surgical pathology were examined by CEUS. Then time-intensity curve analysis was performed. Results 16 lesions were found in the benign group and 14 lesions were in the malignant group. Five parameters of benign and malignant group were statistically analyzed， including Perfusion slope rate（ C），intensity of peak（A），Subsidence slope rate （K）， time of peak value（T） and area under the curve（Area）. The perfusion slope rate（C） of benign and malignant group is [（0.24±0.41）vs（0.67±0.39）]. There was no statistical difference between the two groups in intensity of peak（A）， Subsidence slope rate （K）， time of peak value（T）and area under the curve（Area），except perfusion slope rate （P＜0.05） . Conclusion Time-intensity curve analysis of CEUS has certain effect on differential diagnosis of malignant and benign breast masses.
2016, 37(09)
Abstract:
［Abstract］Objective To investigate the effectiveness of deep brain stimulation (DBS) treating Parkinson's disease. Methods Forty cases of Parkinson's disease were selected from March 2014 to August 2015. The clinical symptoms of these patients were described and quantitatively analyzed with Unified Parkinson's Disease Rating Scale（UPDRS）before and after the procedure of DBS surgery. Results After deep brain stimulation surgery，the symptoms including muscle stiffness, static tremor, bradykinesia were improved，UPDRS scores were significantly lower and the demanding dosage of Parkinson disease drugs such as L-dopa/benserazide and L-dopa/carbidopa were also reduced. Conclusion Deep brain stimulation for Parkinson's disease is safe and effective. It can obviously control the symptoms, reduce the dosage of oral drugs, and improve the quality of life.
［Abstract］Objective To investigate the effectiveness of deep brain stimulation (DBS) treating Parkinson's disease. Methods Forty cases of Parkinson's disease were selected from March 2014 to August 2015. The clinical symptoms of these patients were described and quantitatively analyzed with Unified Parkinson's Disease Rating Scale（UPDRS）before and after the procedure of DBS surgery. Results After deep brain stimulation surgery，the symptoms including muscle stiffness, static tremor, bradykinesia were improved，UPDRS scores were significantly lower and the demanding dosage of Parkinson disease drugs such as L-dopa/benserazide and L-dopa/carbidopa were also reduced. Conclusion Deep brain stimulation for Parkinson's disease is safe and effective. It can obviously control the symptoms, reduce the dosage of oral drugs, and improve the quality of life.
2016, 37(09)
Abstract:
［Abstract］Objective To investigate effects of multimodal analgesia on cytokines and cortisol levels in patients received surgical treatment for radical colon cancer. Methods Eighty-six patients with radical colon cancer treated with surgery were randomly divided into control group and observation group. The control group only received routine epidural anesthesia and the observation group received multimodal analgesia. Preoperative and postoperative VAS scores，cytokines and cortisol levels were measured. Results Compared with those of the control group，the following 5 indicators decreased significantly in the observation group including VAS scores of after 24 h，48 h，72 h， IL-8 and TNF-α after 24 h，IL-6，IL-8 and TNF-α after 48 h， Cor after 24h，and Cor and ACTH after 48 h（P＜0.05）. Conclusion Perioperative multi-mode analgesia helps relieve pain，stress and inflammatory cytokines among patients after the surgery for radical colon cancer.
［Abstract］Objective To investigate effects of multimodal analgesia on cytokines and cortisol levels in patients received surgical treatment for radical colon cancer. Methods Eighty-six patients with radical colon cancer treated with surgery were randomly divided into control group and observation group. The control group only received routine epidural anesthesia and the observation group received multimodal analgesia. Preoperative and postoperative VAS scores，cytokines and cortisol levels were measured. Results Compared with those of the control group，the following 5 indicators decreased significantly in the observation group including VAS scores of after 24 h，48 h，72 h， IL-8 and TNF-α after 24 h，IL-6，IL-8 and TNF-α after 48 h， Cor after 24h，and Cor and ACTH after 48 h（P＜0.05）. Conclusion Perioperative multi-mode analgesia helps relieve pain，stress and inflammatory cytokines among patients after the surgery for radical colon cancer.
2016, 37(09)
Abstract:
［Abstract］Objective To evaluate the clinical value of ultrasound in evaluating the wrist nerve stem．Methods The examination of the high-resolution ultrasound about normal median nerve，ulnar nerve，radial nerve in the wrist on 100 normal volunteers，the courser，shape and sonographic appearance of the nerve stem were observed，and the vertical and horizontal diameter and the area of cross-section were measured．Results（1）Ultrasound clearly showed the nerve stem arranged and organization structures around it.（2）Ultrasound entirely measured the vertical and horizontal sections of normal median nerve，ulnar nerve，radial nerve in the wrist，besides it measured various diameters and the cross-section area. By comparing the vertical diameter of MN and RN between left hand and right hand of the same sexuality，the difference had no statistical significance（P＞0.05）.By comparing the various diameters of UN between left hand and right hand of females，the difference had no statistical significance（P＞0.05）．By comparing the vertical diameter between left hand and right hand of male ，the difference had statistical significance（P＜0.05）.To compare the vertical diameter of MN， RN and UN between male and females on the same side，the difference had statistical significance （P＜0.05）.To compare the CSA of MN， RN and UN between left hand and right hand of the same sexiuality， the diffevence had no statistical significance（P＞0.05）；By comparing the CSA of MN，RN and UN between male and females on the same side，the diffevence had statistical significance（P＜0.05）.Median nerve cross-sectional area （CSA） and weight correlation was statistically significant （P < 0.05） in a straight line， no statistically significant correlation was found between age and height （P > 0.05）. （3）High resolution ultrasound clearly showed the neural surrounding adjacent to the organizational structure，and in line with gross anatomy section. Conclusion Ultraound has a clinical evalution value for examing the wrist nerve
［Abstract］Objective To evaluate the clinical value of ultrasound in evaluating the wrist nerve stem．Methods The examination of the high-resolution ultrasound about normal median nerve，ulnar nerve，radial nerve in the wrist on 100 normal volunteers，the courser，shape and sonographic appearance of the nerve stem were observed，and the vertical and horizontal diameter and the area of cross-section were measured．Results（1）Ultrasound clearly showed the nerve stem arranged and organization structures around it.（2）Ultrasound entirely measured the vertical and horizontal sections of normal median nerve，ulnar nerve，radial nerve in the wrist，besides it measured various diameters and the cross-section area. By comparing the vertical diameter of MN and RN between left hand and right hand of the same sexuality，the difference had no statistical significance（P＞0.05）.By comparing the various diameters of UN between left hand and right hand of females，the difference had no statistical significance（P＞0.05）．By comparing the vertical diameter between left hand and right hand of male ，the difference had statistical significance（P＜0.05）.To compare the vertical diameter of MN， RN and UN between male and females on the same side，the difference had statistical significance （P＜0.05）.To compare the CSA of MN， RN and UN between left hand and right hand of the same sexiuality， the diffevence had no statistical significance（P＞0.05）；By comparing the CSA of MN，RN and UN between male and females on the same side，the diffevence had statistical significance（P＜0.05）.Median nerve cross-sectional area （CSA） and weight correlation was statistically significant （P < 0.05） in a straight line， no statistically significant correlation was found between age and height （P > 0.05）. （3）High resolution ultrasound clearly showed the neural surrounding adjacent to the organizational structure，and in line with gross anatomy section. Conclusion Ultraound has a clinical evalution value for examing the wrist nerve
2016, 37(09)
Abstract:
［Abstract］Objective To study the influence of Naikan therapy on the family function in patients with anxiety disorder of cerebral infarction. Methods A total of 192 patients with anxiety disorder of cerebral infarction were divided into control group and study group according to the set sequence. The study group was treated with Naikan therapy and the control group received routine therapy. All patients were assessed by family assessment device （FAD），Hamilton depression scale（HAMD），and Hamilton anxiety scale （HAMA）. Results After 6-week treatment，the HAMD，HAMA，the affective reaction and behavior control scores in the study group were significantly lower than those before the treatment（t = 2.24，2.43，2.37，2.35，P < 0.05）. The affective reaction and behavior control in the study group were obviously lower than that of the control group （t = 2.51，2.41，P < 0.05）. Conclusion Naikan therapy can improve family function in patients with anxiety disorder of cerebral infarction.
［Abstract］Objective To study the influence of Naikan therapy on the family function in patients with anxiety disorder of cerebral infarction. Methods A total of 192 patients with anxiety disorder of cerebral infarction were divided into control group and study group according to the set sequence. The study group was treated with Naikan therapy and the control group received routine therapy. All patients were assessed by family assessment device （FAD），Hamilton depression scale（HAMD），and Hamilton anxiety scale （HAMA）. Results After 6-week treatment，the HAMD，HAMA，the affective reaction and behavior control scores in the study group were significantly lower than those before the treatment（t = 2.24，2.43，2.37，2.35，P < 0.05）. The affective reaction and behavior control in the study group were obviously lower than that of the control group （t = 2.51，2.41，P < 0.05）. Conclusion Naikan therapy can improve family function in patients with anxiety disorder of cerebral infarction.
2016, 37(09)
Abstract:
［Abstract］Objective To analyze the application of human blood albumin among patients with traumatic fracture. Methods A retrospective analysis was conducted in 86 patients with hypoalbuminemia after traumatic fracture from December 2013 to May 2014 in our hospital，including 43 patients with closed fractures and 43 patients with open fracture. To observe the curative effect，patients with closed fracture and open fracture were divided into the treatment group and the control group respectively according to the use of human albumin. Results Among the patients with closed fracture in the therapeutic group and the control group，wound healing time，soft tissue swelling fade time，white blood cell count， neutrophil percentage， c-reactive protein and wound infection rates were compared and no significant differences were seen（P＞0.05）. In terms of the treatment of open fractures， the observed indicators showed statistical significance after the application of human blood albumin compared with the control group（P＜0.05）. Conclusion Not all the patients with hypoalbuminemia after traumatic fractures are suitable for the application of human blood albumin at the first place. Advantages are seen among patients with hypoalbuminemia after open fractures when they are applied with human blood albumin. Human blood albumin can promote postoperative recovery of the fractures and reduce the risk of infection，which is worthy of popularization and application.
［Abstract］Objective To analyze the application of human blood albumin among patients with traumatic fracture. Methods A retrospective analysis was conducted in 86 patients with hypoalbuminemia after traumatic fracture from December 2013 to May 2014 in our hospital，including 43 patients with closed fractures and 43 patients with open fracture. To observe the curative effect，patients with closed fracture and open fracture were divided into the treatment group and the control group respectively according to the use of human albumin. Results Among the patients with closed fracture in the therapeutic group and the control group，wound healing time，soft tissue swelling fade time，white blood cell count， neutrophil percentage， c-reactive protein and wound infection rates were compared and no significant differences were seen（P＞0.05）. In terms of the treatment of open fractures， the observed indicators showed statistical significance after the application of human blood albumin compared with the control group（P＜0.05）. Conclusion Not all the patients with hypoalbuminemia after traumatic fractures are suitable for the application of human blood albumin at the first place. Advantages are seen among patients with hypoalbuminemia after open fractures when they are applied with human blood albumin. Human blood albumin can promote postoperative recovery of the fractures and reduce the risk of infection，which is worthy of popularization and application.
2016, 37(09)
Abstract:
［Abstract］Objective To study the surgical effect of sylvian lateral fissure approach in the treatment of patients with hypertensive intracerebral hemorrhage on basal ganglia. Methods Sixty-two patients with hypertensive intracerebral hemorrhage on basal ganglia in our hospital from October 2012 to June 2015 were selected， and equally divided into control group and observation group. The control group was treated with temporal cortex approach surgery，and the observation group was treated with sylvian lateral fissure approach surgery. The hematoma clearance rates of different amount of bleeding，and nerve function indexes and ADL score before the treatment and at different time after the treatment of two groups were compared．Results The hematoma clearance rates of observation group with different amount of bleeding were higher than those of control group. The serum nerve function indexes were lower than those of control group. The ADL scores were better than those of control group. The above differences were statistically significant（P＜0.05）. Conclusion The clinical effect of sylvian lateral fissure approach in the treatment of patients with hypertensive intracerebral hemorrhage on basal ganglia is better. The approach has an active role in the improvement of the hematoma clearance and nerve function and greater value for the patients with hypertensive intracerebral hemorrhage on basal ganglia.
［Abstract］Objective To study the surgical effect of sylvian lateral fissure approach in the treatment of patients with hypertensive intracerebral hemorrhage on basal ganglia. Methods Sixty-two patients with hypertensive intracerebral hemorrhage on basal ganglia in our hospital from October 2012 to June 2015 were selected， and equally divided into control group and observation group. The control group was treated with temporal cortex approach surgery，and the observation group was treated with sylvian lateral fissure approach surgery. The hematoma clearance rates of different amount of bleeding，and nerve function indexes and ADL score before the treatment and at different time after the treatment of two groups were compared．Results The hematoma clearance rates of observation group with different amount of bleeding were higher than those of control group. The serum nerve function indexes were lower than those of control group. The ADL scores were better than those of control group. The above differences were statistically significant（P＜0.05）. Conclusion The clinical effect of sylvian lateral fissure approach in the treatment of patients with hypertensive intracerebral hemorrhage on basal ganglia is better. The approach has an active role in the improvement of the hematoma clearance and nerve function and greater value for the patients with hypertensive intracerebral hemorrhage on basal ganglia.
2016, 37(09)
Abstract:
［Abstract］Objective To observe the curative effect of repairing the distal foot skin and soft tissue defect by using flap. Methods We used nutrient artery flap and low external ankle to repair the foot distal skin soft tissue defect in 16 cases. Results The flap survived， necrosis happened in small skin edge part and distal skin flap of sural nerve nutrient artery flap in two cases， and the skin graft healing with dots after removed the necrotic tissue and changed dressing. 16 cases were followed up for 3-16 months， 2 cases of flap slightly bloated，1 case back to the hospital got thin skin flap repairing technique；14 cases of walking were as usual，2 lame cases，related to some tissue defect in patients with forefoot injury. The use of flap to repair the foot injury，could maximially recover the limb function，reduce the rate of the sick. Conclusion Skin flap is a kind of operation which is simple，with smaller cost for skin area，beautiful and effective to repair skin and soft tissue defect of foot.
［Abstract］Objective To observe the curative effect of repairing the distal foot skin and soft tissue defect by using flap. Methods We used nutrient artery flap and low external ankle to repair the foot distal skin soft tissue defect in 16 cases. Results The flap survived， necrosis happened in small skin edge part and distal skin flap of sural nerve nutrient artery flap in two cases， and the skin graft healing with dots after removed the necrotic tissue and changed dressing. 16 cases were followed up for 3-16 months， 2 cases of flap slightly bloated，1 case back to the hospital got thin skin flap repairing technique；14 cases of walking were as usual，2 lame cases，related to some tissue defect in patients with forefoot injury. The use of flap to repair the foot injury，could maximially recover the limb function，reduce the rate of the sick. Conclusion Skin flap is a kind of operation which is simple，with smaller cost for skin area，beautiful and effective to repair skin and soft tissue defect of foot.
2016, 37(09)
Abstract:
［Abstract］Bone and soft tissue tumors are one of the most difficult tumors to be diagnosed in terms of various kinds， complicated manifestations under the microscope， and atypical clinical features. Most bone and soft tissue tumors cause the metastasis in surrounding vital organs， where multidisciplinary teamwork is critically needed. Traditional models are not able to meet the needs of the diagnosis and treatment. Therefore， we should actively develop the MDT （Multi-Disciplinary Team） strategy of the diagnosis and treatment of the bone and soft tissue tumors to reduce the missed diagnosis rate and misdiagnosis rate and improve the survival rate and patients' quality of life by enhancing accessibility to the reasonable， standardized and accurate treatment.
［Abstract］Bone and soft tissue tumors are one of the most difficult tumors to be diagnosed in terms of various kinds， complicated manifestations under the microscope， and atypical clinical features. Most bone and soft tissue tumors cause the metastasis in surrounding vital organs， where multidisciplinary teamwork is critically needed. Traditional models are not able to meet the needs of the diagnosis and treatment. Therefore， we should actively develop the MDT （Multi-Disciplinary Team） strategy of the diagnosis and treatment of the bone and soft tissue tumors to reduce the missed diagnosis rate and misdiagnosis rate and improve the survival rate and patients' quality of life by enhancing accessibility to the reasonable， standardized and accurate treatment.
2016, 37(09)
Abstract:
［Abstract］Objective To learn current status and influentcing factors of post competency among preventive medicine graduates from a medical university，in order to provide evidence for the improvement of post competency preventive medicine graduates．Methods We adopted stratified sampling strategy，chose 1 provincial，1 municipal and 2 county level CDCs，used self-developed questionnaires to survey preventive medicine graduates from a specific medical university. Clustering analysis，correlation analysis, Logistic regression and rank-sum test were applied to analyze data．Results Among all respondents，26 (40.63%) reported that they were totally competent on their posts，the rest 38 (59.37%) reported ordinary post competency. We found 7 factors that were significantly associated with post competency: fondness of the job，whether proactive on the job，whether responsible to the job，et al. Conclusion Post competency of preventive medicine graduates from this particular medical university exceeded preventive medicine graduates from Xinjiang Medical University. However, there still exists some problems for improvement. We recommend that universities and working units should improve post competency of preventive medicine students based on those influential factors we identified.
［Abstract］Objective To learn current status and influentcing factors of post competency among preventive medicine graduates from a medical university，in order to provide evidence for the improvement of post competency preventive medicine graduates．Methods We adopted stratified sampling strategy，chose 1 provincial，1 municipal and 2 county level CDCs，used self-developed questionnaires to survey preventive medicine graduates from a specific medical university. Clustering analysis，correlation analysis, Logistic regression and rank-sum test were applied to analyze data．Results Among all respondents，26 (40.63%) reported that they were totally competent on their posts，the rest 38 (59.37%) reported ordinary post competency. We found 7 factors that were significantly associated with post competency: fondness of the job，whether proactive on the job，whether responsible to the job，et al. Conclusion Post competency of preventive medicine graduates from this particular medical university exceeded preventive medicine graduates from Xinjiang Medical University. However, there still exists some problems for improvement. We recommend that universities and working units should improve post competency of preventive medicine students based on those influential factors we identified.
2016, 37(09)
Abstract:
［Abstract］Objective To explore the influence of continuing nursing care on sexual quality of patients after laparoscopic subtotal hysterectomy. Methods Seventy-eight patients with selective laparoscopic subtotal hysterectomy enrolled from March 2014 to April 2015 were numbered according to their enrollment date， and divided into control group and intervention group randomly. Both groups were conducted laparoscopic subtotal hysterectomy under general anesthesia. After the surgery， the control group was treated with standard nursing care and the intervention group received continuing nursing care beyond the standard nursing care. Participants' sexual quality of 3 months and 6 months after surgery were evaluated using the female sexual function index （FSFI）. Results The scores of FSFI of intervention group were significantly higher than those of the control group. Conclusion The continuing nursing care of patients after laparoscopic subtotal hysterectomy can effectively improve patient's short-term sexual quality， which is worth of being applied in gynecology nursing care in the future.
［Abstract］Objective To explore the influence of continuing nursing care on sexual quality of patients after laparoscopic subtotal hysterectomy. Methods Seventy-eight patients with selective laparoscopic subtotal hysterectomy enrolled from March 2014 to April 2015 were numbered according to their enrollment date， and divided into control group and intervention group randomly. Both groups were conducted laparoscopic subtotal hysterectomy under general anesthesia. After the surgery， the control group was treated with standard nursing care and the intervention group received continuing nursing care beyond the standard nursing care. Participants' sexual quality of 3 months and 6 months after surgery were evaluated using the female sexual function index （FSFI）. Results The scores of FSFI of intervention group were significantly higher than those of the control group. Conclusion The continuing nursing care of patients after laparoscopic subtotal hysterectomy can effectively improve patient's short-term sexual quality， which is worth of being applied in gynecology nursing care in the future.
