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RSS2016 Vol. 37, No. 11
2016, 37(11): 1-4.
Abstract:
Objective To investigate the effects of anticancer bioactive fraction AMH-T of lichen on blood routine, organ coefficient and organ morphology by carrying out short-term repeated dose toxicity test in rat so as to provide evidence for the development of anticancer drugs. Methods The nude mice were randomly divided into 5groups: DDP group, DMSO group, and three AMH-T groups with the dosage of 50mg/kg, 100mg/kg, and 200 mg/kg respectively. The weights of the mice were recorded every four days. At the end of the experiment, automatic biochemical analyzer and blood cell analyzer were applied to detect the serum biochemical indicators and blood routine indexes. The mice were dissected to observe the pathological changes in main organs. Heart, liver, spleen,kidney and testicle were weighed for organ coefficient calculation. Results In short-term repeated dose toxicity test,AMH-T significantly increased blood ALT and AST levels(P<0.01) and significant change was found in other blood biochemical indexes and blood routine indexes. AMH-T had no obvious effect on weight,development of heart, liver,spleen, kidney and testicle. Conclusion When subcutaneous injection is performed, AMH-T shows hepatotoxicity,but it shows no toxicity on bone marrow hematopoietic function.
Objective To investigate the effects of anticancer bioactive fraction AMH-T of lichen on blood routine, organ coefficient and organ morphology by carrying out short-term repeated dose toxicity test in rat so as to provide evidence for the development of anticancer drugs. Methods The nude mice were randomly divided into 5groups: DDP group, DMSO group, and three AMH-T groups with the dosage of 50mg/kg, 100mg/kg, and 200 mg/kg respectively. The weights of the mice were recorded every four days. At the end of the experiment, automatic biochemical analyzer and blood cell analyzer were applied to detect the serum biochemical indicators and blood routine indexes. The mice were dissected to observe the pathological changes in main organs. Heart, liver, spleen,kidney and testicle were weighed for organ coefficient calculation. Results In short-term repeated dose toxicity test,AMH-T significantly increased blood ALT and AST levels(P<0.01) and significant change was found in other blood biochemical indexes and blood routine indexes. AMH-T had no obvious effect on weight,development of heart, liver,spleen, kidney and testicle. Conclusion When subcutaneous injection is performed, AMH-T shows hepatotoxicity,but it shows no toxicity on bone marrow hematopoietic function.
2016, 37(11): 5-7.
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Objective To study the chemical constituents from the flowers of Arundina graminifolia and to find its bioactive compounds. Methods The compounds were extracted by 95% alcohol and isolated by column chromatography on silica gel and Sephadex LH-20. The structures were identified by spectroscopic analysis(1H NMR,13 CNMR and EIMS). Results Eight compounds were obtained and identified as(1) 7-hydroxy-2,4-dimethoxy-9,10-dihydrophenanthrene;(2)coelonin;(3)4,7-dihydroxy-2-methoxy-9,10-dihydro-phenanthrene;(4)ephemeranthoquinone;(5)densiflorol B;(6)4-(3-hydroxyphenyl)-2-butanone;(7)stigmasterol,(8)β-sitosterol.Conclusion Among them, compound 6 is discovered for the first time from the plant.
Objective To study the chemical constituents from the flowers of Arundina graminifolia and to find its bioactive compounds. Methods The compounds were extracted by 95% alcohol and isolated by column chromatography on silica gel and Sephadex LH-20. The structures were identified by spectroscopic analysis(1H NMR,13 CNMR and EIMS). Results Eight compounds were obtained and identified as(1) 7-hydroxy-2,4-dimethoxy-9,10-dihydrophenanthrene;(2)coelonin;(3)4,7-dihydroxy-2-methoxy-9,10-dihydro-phenanthrene;(4)ephemeranthoquinone;(5)densiflorol B;(6)4-(3-hydroxyphenyl)-2-butanone;(7)stigmasterol,(8)β-sitosterol.Conclusion Among them, compound 6 is discovered for the first time from the plant.
2016, 37(11): 8-13.
Abstract:
Objective To establish a gestational diabetes rat model by feeding the rats with high-fat diet.Methods A total of 55 female SD rats were divided into four groups: NV group, NP group, FV group and FP group. Three months after normal feeding, the female rats in NP and FP group were put into the same cage with the male rats at the ratio of 2:1 and were given high-fat diet or normal diet as usual. Before pregnancy and day1,7,14,20 in pregnancy,fasting plasma glucose and body weight of rats were detected. The fasting serum insulin and serum c-peptide levels were monitored by enzyme immunoassay and insulin resistance index was calculated. At late pregnancy, glucose tolerance and the indicator of fat were tested. Liver and pancreas were dyed to be observed under microscope. Results Body weights of the rats raised with high-fat diet were significantly higher than those of control group and body weight during pregnancy significantly increased(P<0.05). Fasting glucose,fasting insulin and serum C-peptide in FP group were significantly higher than those in NP group and insulin resistance was evident(P<0.05). The area under curve of GTT in FP group was significantly larger(P<0.05).The levels of serum lipids in FP group were higher than those in normal group. Conclusions The gestational diabetes rat model induced by high-fat diet can be successfully established.The model presents major pathophysiological manifestations of GDM and can be used as a good model of GDM in relevant research.
Objective To establish a gestational diabetes rat model by feeding the rats with high-fat diet.Methods A total of 55 female SD rats were divided into four groups: NV group, NP group, FV group and FP group. Three months after normal feeding, the female rats in NP and FP group were put into the same cage with the male rats at the ratio of 2:1 and were given high-fat diet or normal diet as usual. Before pregnancy and day1,7,14,20 in pregnancy,fasting plasma glucose and body weight of rats were detected. The fasting serum insulin and serum c-peptide levels were monitored by enzyme immunoassay and insulin resistance index was calculated. At late pregnancy, glucose tolerance and the indicator of fat were tested. Liver and pancreas were dyed to be observed under microscope. Results Body weights of the rats raised with high-fat diet were significantly higher than those of control group and body weight during pregnancy significantly increased(P<0.05). Fasting glucose,fasting insulin and serum C-peptide in FP group were significantly higher than those in NP group and insulin resistance was evident(P<0.05). The area under curve of GTT in FP group was significantly larger(P<0.05).The levels of serum lipids in FP group were higher than those in normal group. Conclusions The gestational diabetes rat model induced by high-fat diet can be successfully established.The model presents major pathophysiological manifestations of GDM and can be used as a good model of GDM in relevant research.
2016, 37(11): 14-17.
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Objective To investigate the mutation of hemagglutinin gene and amino acid variation of influenza B. Methods Influenza B virus was isolated from throat swab samples in sentinel surveillance of Yunnan province from 2009 to 2014. HA1 gene sequence analysis was applied to determine 12 randomly-selected strains of influenza B virus. The results were analyzed,MEGA software was used to do homology comparison and HA gene phylogenetic tree was established.Results Differences on the serotype and genotype identification of influenza strains were found and it might be caused by inadequate gene mutation accumulation. Amino acid variations were found in 3 important regions of antigenic determinants in HA1 protein: ring 120, ring 150 and ring 160. The amino acid variation of position 131 in ring 120 was N131 K, and in position 137 was N137 H. Two strains had P187 S mutation in position 187. Conclusion There are some important variations in the hemagglutinin gene of influenza B strains in Yunnan Province,with some variations being the same as vaccine strains and some being not.
Objective To investigate the mutation of hemagglutinin gene and amino acid variation of influenza B. Methods Influenza B virus was isolated from throat swab samples in sentinel surveillance of Yunnan province from 2009 to 2014. HA1 gene sequence analysis was applied to determine 12 randomly-selected strains of influenza B virus. The results were analyzed,MEGA software was used to do homology comparison and HA gene phylogenetic tree was established.Results Differences on the serotype and genotype identification of influenza strains were found and it might be caused by inadequate gene mutation accumulation. Amino acid variations were found in 3 important regions of antigenic determinants in HA1 protein: ring 120, ring 150 and ring 160. The amino acid variation of position 131 in ring 120 was N131 K, and in position 137 was N137 H. Two strains had P187 S mutation in position 187. Conclusion There are some important variations in the hemagglutinin gene of influenza B strains in Yunnan Province,with some variations being the same as vaccine strains and some being not.
2016, 37(11): 18-22.
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Objective To discuss the influencing factors of lead poisoning in children and adolescents in certain region of Yunnan and to provide evidence for effective prevention measures. Methods Venous blood samples of 1379 children and adolescents were collected and lead levels in the blood were tested by atomic absorption spectrometer. Children and adolescents with lead level higher than 100 μg/L were diagnosed with lead poisoning.Results The lead level ranged from 1 μg/L to 450 μg/L, with the average level of 82.87±66.97 μg/L,and 341 children and adolescents were diagnosed with lead poisoning, with the poisoning rate of 24.7%. The differences of lead poisoning rates by gender, age, and place of residence were significant(P<0.05). Gender, age, and distance between place of residence and mining area were the main influencing factors of the lead poisoning rate.Conclusion The blood lead poisoning rate of children and adolescent are high in this region. Boys, children in preschool age and children living closer to the mining area are susceptible to blood lead poisoning.
Objective To discuss the influencing factors of lead poisoning in children and adolescents in certain region of Yunnan and to provide evidence for effective prevention measures. Methods Venous blood samples of 1379 children and adolescents were collected and lead levels in the blood were tested by atomic absorption spectrometer. Children and adolescents with lead level higher than 100 μg/L were diagnosed with lead poisoning.Results The lead level ranged from 1 μg/L to 450 μg/L, with the average level of 82.87±66.97 μg/L,and 341 children and adolescents were diagnosed with lead poisoning, with the poisoning rate of 24.7%. The differences of lead poisoning rates by gender, age, and place of residence were significant(P<0.05). Gender, age, and distance between place of residence and mining area were the main influencing factors of the lead poisoning rate.Conclusion The blood lead poisoning rate of children and adolescent are high in this region. Boys, children in preschool age and children living closer to the mining area are susceptible to blood lead poisoning.
2016, 37(11): 23-27.
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Objective To study the role of water exact from salvia miltiorrhiza(SM) in promoting hair regrowth in testosterone(T)-induced alopecia in mice. Methods Pathological alopecia mice were induced by T and the mice were randomly divided into control group, model group, Zhanggvanp 101 group, SM low-dose group,SM middle-dose group,SM high-dose group(20, 40, 80 mg/ml, respectively). The effects of SM on hair regrowth were evaluated by measuring hair length, weight and the number of hair follicle. The concentration of serum T and estrodiol(E2), the content of skin VEGF, MDA, SOD, and GSH-Px were measured after external inunctum for 21 days. Results(1) SM significantly promoted regrowth hair length, weight and the number of hair follicle(P<0.05).(2) SM significantly balanced the hormones by reducing levels of T and increasing E2(P<0.05).(3) SM significantly reduced the content of MDA by increasing the activity of SOD and GSH-Px(P<0.05).(4) SM significantly increased the level of VEGF(P<0.05). Conclusion In the pathological alopecia mice induced by T, SM can effectively promote the hair regrowth, with the possible mechanism of balancing hormones, being anti-oxidant and improving VEGF expression.
Objective To study the role of water exact from salvia miltiorrhiza(SM) in promoting hair regrowth in testosterone(T)-induced alopecia in mice. Methods Pathological alopecia mice were induced by T and the mice were randomly divided into control group, model group, Zhanggvanp 101 group, SM low-dose group,SM middle-dose group,SM high-dose group(20, 40, 80 mg/ml, respectively). The effects of SM on hair regrowth were evaluated by measuring hair length, weight and the number of hair follicle. The concentration of serum T and estrodiol(E2), the content of skin VEGF, MDA, SOD, and GSH-Px were measured after external inunctum for 21 days. Results(1) SM significantly promoted regrowth hair length, weight and the number of hair follicle(P<0.05).(2) SM significantly balanced the hormones by reducing levels of T and increasing E2(P<0.05).(3) SM significantly reduced the content of MDA by increasing the activity of SOD and GSH-Px(P<0.05).(4) SM significantly increased the level of VEGF(P<0.05). Conclusion In the pathological alopecia mice induced by T, SM can effectively promote the hair regrowth, with the possible mechanism of balancing hormones, being anti-oxidant and improving VEGF expression.
2016, 37(11): 28-32.
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Objective To investigate the dynamic changes of articular cartilage destruction and nitric oxide nitric oxide/inducible nitric oxide synthase(NO/i NOS). Methods Forty healthy adult male Wistar rats were randomly divided into control group(free movement) and experimental group(overtraining). Total knee joints of rat were collected at week 0,1,2,3,and 6,fixed with 4% PFA,embedded in paraffin, sectioned and stained. Cartilage morphological changes were observed by Safranin-O staining, NO/i NOS content changes in serum and synovial fluid were determined by ELISA,Mankin's scores were obtained, and cartilage pathological changes were analyzed. Results Overtraining resulted in cell sorting disorders, loss of matrix, destruction like rough surface and cracks, and degeneration of cartilage pathology process. Levels of NO/i NOS in serum and synovial fluid increased after overtraining:week 1(48.088±1.534),(3.058±0.073);week 2(54.574±0.800),(6.630±0.524);week 3(68.020±3.184),(7.384±0.306);weeks 6(104.394±8.094),(11.364±0.882).Levels of NO/i NOS in synovial fluid group were: week 1(65.814 ±1.610),(8.126 ±0.724); week 2(72.766±2.344),(9.694±0.564);week 3(88.816±0.819),(11.326±1.473);week 6(120.204±12.044),(15.166±1.198),and high level of concentration was found with the increasing amount of exercise.Conclusion There is a positive correlation between the levels of NO/i NOS in synovial fluid or serum and the extent of the damage of articular cartilage.
Objective To investigate the dynamic changes of articular cartilage destruction and nitric oxide nitric oxide/inducible nitric oxide synthase(NO/i NOS). Methods Forty healthy adult male Wistar rats were randomly divided into control group(free movement) and experimental group(overtraining). Total knee joints of rat were collected at week 0,1,2,3,and 6,fixed with 4% PFA,embedded in paraffin, sectioned and stained. Cartilage morphological changes were observed by Safranin-O staining, NO/i NOS content changes in serum and synovial fluid were determined by ELISA,Mankin's scores were obtained, and cartilage pathological changes were analyzed. Results Overtraining resulted in cell sorting disorders, loss of matrix, destruction like rough surface and cracks, and degeneration of cartilage pathology process. Levels of NO/i NOS in serum and synovial fluid increased after overtraining:week 1(48.088±1.534),(3.058±0.073);week 2(54.574±0.800),(6.630±0.524);week 3(68.020±3.184),(7.384±0.306);weeks 6(104.394±8.094),(11.364±0.882).Levels of NO/i NOS in synovial fluid group were: week 1(65.814 ±1.610),(8.126 ±0.724); week 2(72.766±2.344),(9.694±0.564);week 3(88.816±0.819),(11.326±1.473);week 6(120.204±12.044),(15.166±1.198),and high level of concentration was found with the increasing amount of exercise.Conclusion There is a positive correlation between the levels of NO/i NOS in synovial fluid or serum and the extent of the damage of articular cartilage.
The Apoptosis Effect of Docetaxel Combined with Gamma Knife on Hepatoma Cells Xenograft in Nude Mice
2016, 37(11): 33-36.
Abstract:
Objective To explore the apoptosis effect of docetaxel combined gamma knife on hepatoma cell SMMC-7721 subcutaneous xenograft in nude mice. Methods Subcutaneous xenograft models were constructed and were divided into two groups: control group and experimental group. The experimental group was treated with docetaxel 60ug/0.3ml once every 3 days for 6 times and gamma irradiation once every other day for 6 times(with indoor temperature of137 Cs radiation source irradiating the tumor and of fractionated schedule 5Gy with the total dose of 10 Gy every time). The control group was treated with physiological saline with the same dose of 60 ug/0.3 m L.Tumor growth was observed. Tumor samples were cut 30 days after the treatment and TUNEL was used to detect the apoptosis of tumor cells. Results Tumor growth rate in experimental group significantly slowed down. Apoptotic index in experimental groups was significantly higher than that in control group(P < 0.05). Conclusion Docetaxel combined gamma knife can inhibit the growth of hepatocellular carcinoma in nude mice.
Objective To explore the apoptosis effect of docetaxel combined gamma knife on hepatoma cell SMMC-7721 subcutaneous xenograft in nude mice. Methods Subcutaneous xenograft models were constructed and were divided into two groups: control group and experimental group. The experimental group was treated with docetaxel 60ug/0.3ml once every 3 days for 6 times and gamma irradiation once every other day for 6 times(with indoor temperature of137 Cs radiation source irradiating the tumor and of fractionated schedule 5Gy with the total dose of 10 Gy every time). The control group was treated with physiological saline with the same dose of 60 ug/0.3 m L.Tumor growth was observed. Tumor samples were cut 30 days after the treatment and TUNEL was used to detect the apoptosis of tumor cells. Results Tumor growth rate in experimental group significantly slowed down. Apoptotic index in experimental groups was significantly higher than that in control group(P < 0.05). Conclusion Docetaxel combined gamma knife can inhibit the growth of hepatocellular carcinoma in nude mice.
2016, 37(11): 37-40.
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Objective To explore the effect of Paridissaponin I(PSI) on the proliferation of coronary artery endothelial cells(CAECs). Methods CAECs were cultured with PSI. CAEC growth rate was calculated by using blood cell counting plate. Cell viability was measured by MTT. The expressions of cadherin and caspase3 m RNA were detected by RT-PCR. Results PSI slowed down growth rate of CAECs, reduced cell viability of CAECs,decreased the expression of cadherin m RNA and increased the expression of caspase3 m RNA in CAECs. Conclusion PSI inhibits the proliferation of CAECs and induces CAECs apoptosis.
Objective To explore the effect of Paridissaponin I(PSI) on the proliferation of coronary artery endothelial cells(CAECs). Methods CAECs were cultured with PSI. CAEC growth rate was calculated by using blood cell counting plate. Cell viability was measured by MTT. The expressions of cadherin and caspase3 m RNA were detected by RT-PCR. Results PSI slowed down growth rate of CAECs, reduced cell viability of CAECs,decreased the expression of cadherin m RNA and increased the expression of caspase3 m RNA in CAECs. Conclusion PSI inhibits the proliferation of CAECs and induces CAECs apoptosis.
2016, 37(11): 41-45.
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Objective To investigate the anxiety status of male partner involved in induced abortion and to analyze influencing factors related. Methods Male partners of the patients undergoing induced abortion in the gynecology and obstetrics department of a hospital in Kunming in April and May in 2015 were selected and a questionnaire survey was conducted. Self-rating Anxiety Scale(SAS) was used to measure the anxiety status and SPSS 17.0 was used for statistical analysis.Results A total of 53 out of 205 male partners were found to have anxiety symptoms(25.9%),with 44 cases of mild anxiety(21.5%),8 cases of moderate anxiety(3.9%) and 1 case of severe anxiety(0.5%). The main related risk factor was times of pregnancy(OR=3.35) while the protective factors were level of education(OR=0.60),times of induced abortion(OR=0.20) and age(OR=0.32).Conclusion When abortion occurs, the male partner's anxiety appears, mainly with mild and moderate one, and female's emotion are also affected. It is important to strengthen health education and popularize contraceptive knowledge so as to reduce the incidence of anxiety.
Objective To investigate the anxiety status of male partner involved in induced abortion and to analyze influencing factors related. Methods Male partners of the patients undergoing induced abortion in the gynecology and obstetrics department of a hospital in Kunming in April and May in 2015 were selected and a questionnaire survey was conducted. Self-rating Anxiety Scale(SAS) was used to measure the anxiety status and SPSS 17.0 was used for statistical analysis.Results A total of 53 out of 205 male partners were found to have anxiety symptoms(25.9%),with 44 cases of mild anxiety(21.5%),8 cases of moderate anxiety(3.9%) and 1 case of severe anxiety(0.5%). The main related risk factor was times of pregnancy(OR=3.35) while the protective factors were level of education(OR=0.60),times of induced abortion(OR=0.20) and age(OR=0.32).Conclusion When abortion occurs, the male partner's anxiety appears, mainly with mild and moderate one, and female's emotion are also affected. It is important to strengthen health education and popularize contraceptive knowledge so as to reduce the incidence of anxiety.
2016, 37(11): 46-50.
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Objective To study the change of levels of IL-6, IL-17, IL-23, IL-8, TNF-α and IFN-γ and their clinical significance on children with different types of Henoch-Schonlein purpura(HSP).Methods The blood specimens of 180 children with HSP as disease group and 30 health children as normal group were collected respectively. Disease group included 30 children at acute stage and 30 at convalescence stage of primary abdominal type,30 at acute stage and 30 at convalescence stage of primary non-abdominal type,30 at acute stage of secondary abdominal type,and 30 at acute stage of secondary non-abdominal type. The plasma levels of IL-6,IL-8,IL-17, IL-23, TNF-α and IFN-γ in the two groups were measured by ELISA method for comparison and analysis.Results The plasma levels of IL-6, IL-8, IL-17, IL-23 and TNF-α in disease group were higher than those in the normal group(P<0.05). Those levels in the children at acute stage and of primary group were also found to be higher than those at convalescence stage(P<0.05) and of secondary group(P<0.05) respectively. Comparison of IL-6, IL-8, IL-17, IL-23 and TNF-α between abdominal type and the non-abdominal type had no significant difference(P>0.05). The plasma level of IFN-γ in disease group was lower than those in normal group(P<0.05). The levels of IFN-γ in the children at acute stage and of primary group were lower than those at convalescence stage(P <0.05) and of the secondary group(P <0.05).Comparison of IFN-γ between abdominal type and non-abdominal type had no significant difference(P>0.05).Conclusions The plasma levels of IL-6, IL-8, IL-17, IL-23, TNF-α,IFN-γ show obvious changes in children with HSP, which suggests that the changes of cytokines are associated with the pathogenesis and prognosis of Henoch- Schonlein purpura.
Objective To study the change of levels of IL-6, IL-17, IL-23, IL-8, TNF-α and IFN-γ and their clinical significance on children with different types of Henoch-Schonlein purpura(HSP).Methods The blood specimens of 180 children with HSP as disease group and 30 health children as normal group were collected respectively. Disease group included 30 children at acute stage and 30 at convalescence stage of primary abdominal type,30 at acute stage and 30 at convalescence stage of primary non-abdominal type,30 at acute stage of secondary abdominal type,and 30 at acute stage of secondary non-abdominal type. The plasma levels of IL-6,IL-8,IL-17, IL-23, TNF-α and IFN-γ in the two groups were measured by ELISA method for comparison and analysis.Results The plasma levels of IL-6, IL-8, IL-17, IL-23 and TNF-α in disease group were higher than those in the normal group(P<0.05). Those levels in the children at acute stage and of primary group were also found to be higher than those at convalescence stage(P<0.05) and of secondary group(P<0.05) respectively. Comparison of IL-6, IL-8, IL-17, IL-23 and TNF-α between abdominal type and the non-abdominal type had no significant difference(P>0.05). The plasma level of IFN-γ in disease group was lower than those in normal group(P<0.05). The levels of IFN-γ in the children at acute stage and of primary group were lower than those at convalescence stage(P <0.05) and of the secondary group(P <0.05).Comparison of IFN-γ between abdominal type and non-abdominal type had no significant difference(P>0.05).Conclusions The plasma levels of IL-6, IL-8, IL-17, IL-23, TNF-α,IFN-γ show obvious changes in children with HSP, which suggests that the changes of cytokines are associated with the pathogenesis and prognosis of Henoch- Schonlein purpura.
2016, 37(11): 51-54.
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Objective To analyze and summarize the treatment strategies for unstable angina with no-reflow phenomenon after PTCA during early percutaneous interventional procedures. Methods A total of 32 cases with unstable angina were divided into two groups: one group with drug therapy and the other group with drug therapy and thrombus aspiration catheter. The patients were chosen when there was no-reflow phenomenon after PTCA during early percutaneous interventional procedures and their clinical data were compared and analyzed. Blood flow TIMI grade, myocardial perfusion grade(MBG),TIMI myocardial perfusion(TMP) grade and other indexes were observed and recorded. Results The general conditions had no statistical difference between two groups. Compared with the drug therapy group,the proportion of patients with TIMI,MBG and TMP grade 3 was higher in aspiration and drug therapy group(89% VS 71% P<0.05). Conclusion Drug therapy and thrombus aspiration catheter in treatment helps to improve myocardial perfusion level for unstable angina with no no-reflow phenomenon after PTCA during early percutaneous interventional procedures.
Objective To analyze and summarize the treatment strategies for unstable angina with no-reflow phenomenon after PTCA during early percutaneous interventional procedures. Methods A total of 32 cases with unstable angina were divided into two groups: one group with drug therapy and the other group with drug therapy and thrombus aspiration catheter. The patients were chosen when there was no-reflow phenomenon after PTCA during early percutaneous interventional procedures and their clinical data were compared and analyzed. Blood flow TIMI grade, myocardial perfusion grade(MBG),TIMI myocardial perfusion(TMP) grade and other indexes were observed and recorded. Results The general conditions had no statistical difference between two groups. Compared with the drug therapy group,the proportion of patients with TIMI,MBG and TMP grade 3 was higher in aspiration and drug therapy group(89% VS 71% P<0.05). Conclusion Drug therapy and thrombus aspiration catheter in treatment helps to improve myocardial perfusion level for unstable angina with no no-reflow phenomenon after PTCA during early percutaneous interventional procedures.
2016, 37(11): 55-59.
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Objective To explore the application value of real-time shear wave elastography(SWE)technique in diagnosing and staging of chronic viral hepatitis B and hepatic fibrosis and to establish Young's modulus reference range for diagnosing and staging of hepatic fibrosis.Methods Forty-eight patients with chronic hepatitis B and fifty-eight healthy adults were enrolled and their Young's modulus values of S5 and S6 segments of liver were measured. Histopathologic examination was performed on 48 patients with chronic hepatitis B. Comparative analysis was conducted between the pathological findings and Young's modulus values, by means of which Young's modulus reference range for diagnosis and staging of hepatic fibrosis was obtained. Results There was significant difference in Young's modulus values of S5 and S6 segments of liver between chronic hepatitis B group and the normal control group(P <0.05). Young's modulus values of S5 and S6 segments of liver in chronic hepatitis B group were(11.7±2.9) k Pa and(12.1±3.2) k Pa respectively,which were significantly higher than those in the normal control group,(5.7 ±1.1) k Pa and(5.8 ±1.3) k Pa respectively. Significant differences of Young's modulus values were detected in every staging of hepatic fibrosis(P<0.05). S5 segment of liver Young's modulus values inS0-S4 stages were(5.8±2.2) k Pa,(7.3±1.9) k Pa,(10.3±2.8) k Pa,(10.3±2.8) k Pa,and(25.3±3.6) k Pa, respectively. S6 segment of liver Young's modulus values in S0-S4 stages were(5.7 ±2.3) k Pa,(9.2 ±2.1) k Pa,(10.5 ±2.1) k Pa,(14.7 ±4.5) k Pa, and(26.1 ±2.1) k Pa, respectively. Young's modulus value of the liver rose with the increase of S stage. Conclusion SWE technique can establish the Young's modulus reference range for hepatic fibrosis stage. Besides, it features high sensitivity, specificity and accuracy.
Objective To explore the application value of real-time shear wave elastography(SWE)technique in diagnosing and staging of chronic viral hepatitis B and hepatic fibrosis and to establish Young's modulus reference range for diagnosing and staging of hepatic fibrosis.Methods Forty-eight patients with chronic hepatitis B and fifty-eight healthy adults were enrolled and their Young's modulus values of S5 and S6 segments of liver were measured. Histopathologic examination was performed on 48 patients with chronic hepatitis B. Comparative analysis was conducted between the pathological findings and Young's modulus values, by means of which Young's modulus reference range for diagnosis and staging of hepatic fibrosis was obtained. Results There was significant difference in Young's modulus values of S5 and S6 segments of liver between chronic hepatitis B group and the normal control group(P <0.05). Young's modulus values of S5 and S6 segments of liver in chronic hepatitis B group were(11.7±2.9) k Pa and(12.1±3.2) k Pa respectively,which were significantly higher than those in the normal control group,(5.7 ±1.1) k Pa and(5.8 ±1.3) k Pa respectively. Significant differences of Young's modulus values were detected in every staging of hepatic fibrosis(P<0.05). S5 segment of liver Young's modulus values inS0-S4 stages were(5.8±2.2) k Pa,(7.3±1.9) k Pa,(10.3±2.8) k Pa,(10.3±2.8) k Pa,and(25.3±3.6) k Pa, respectively. S6 segment of liver Young's modulus values in S0-S4 stages were(5.7 ±2.3) k Pa,(9.2 ±2.1) k Pa,(10.5 ±2.1) k Pa,(14.7 ±4.5) k Pa, and(26.1 ±2.1) k Pa, respectively. Young's modulus value of the liver rose with the increase of S stage. Conclusion SWE technique can establish the Young's modulus reference range for hepatic fibrosis stage. Besides, it features high sensitivity, specificity and accuracy.
2016, 37(11): 60-63.
Abstract:
Objective To observe expression level of serum vascular endothelial growth factor-C(VEGF-C), VEGF-C receptor-2 and VEGF-C receptor-3 in patients with acute leukemia(AL) and to explore its clinical significance. Methods Enzyme-linked immuno sorbent assay(ELISA) was used to detect the serum expression levels of VEGF-C, VEGFR-2, and VEGFR-3 of 51 patients diagnosed with acute leukemia, 43 patients under medical treatment and 16 healthy blood donors.Results(1) Serum VEGF-C, VEGFR-2, and VEGFR-3 expression levels in AL patients were significantly higher than those in normal control group.(2) Serum VEGF-C and VEGFR-2 expression levels in complete remission(CR) group significantly declined after treatment.Serum VEGF-C and VEGFR-2 expression levels in non-complete remission(NR) group slightly declined after treatment but no significant difference was found(P>0.05).(3) No significant difference was found in serum VEGFR-3 expression levels both in CR group and NR group after treatment(P>0.05).(4) Serum VEGF-C,VEGFR-2, and VEGFR-3 expression levels in NR group were significantly higher than those in CR group before treatment(P<0.08). Conclusions Observing serum expression level of VEGF-C,VEGFR-2,and VEGFR-3 of AL patients may be helpful in monitoring curative effects and prognosis of acute leukemia.
Objective To observe expression level of serum vascular endothelial growth factor-C(VEGF-C), VEGF-C receptor-2 and VEGF-C receptor-3 in patients with acute leukemia(AL) and to explore its clinical significance. Methods Enzyme-linked immuno sorbent assay(ELISA) was used to detect the serum expression levels of VEGF-C, VEGFR-2, and VEGFR-3 of 51 patients diagnosed with acute leukemia, 43 patients under medical treatment and 16 healthy blood donors.Results(1) Serum VEGF-C, VEGFR-2, and VEGFR-3 expression levels in AL patients were significantly higher than those in normal control group.(2) Serum VEGF-C and VEGFR-2 expression levels in complete remission(CR) group significantly declined after treatment.Serum VEGF-C and VEGFR-2 expression levels in non-complete remission(NR) group slightly declined after treatment but no significant difference was found(P>0.05).(3) No significant difference was found in serum VEGFR-3 expression levels both in CR group and NR group after treatment(P>0.05).(4) Serum VEGF-C,VEGFR-2, and VEGFR-3 expression levels in NR group were significantly higher than those in CR group before treatment(P<0.08). Conclusions Observing serum expression level of VEGF-C,VEGFR-2,and VEGFR-3 of AL patients may be helpful in monitoring curative effects and prognosis of acute leukemia.
2016, 37(11): 64-69.
Abstract:
Objective To compare the early analgesic effects of continuous femoral nerve block analgesia(CFNB) and patient controlled intravenous analgesia(PCIA) and their effects on functional recovery after total knee arthroplasty. Methods Retrospective analysis was conducted on 60 ASA I and ASA II patients with unilateral total knee arthroplasty in our hospital from January 2014 to January 2015. The patients were divided into two groups,CFBN group(treatment group) and PCIA group(control group),with 30 patients in each group. VAS scores of postoperative ipsilateral knee resting and movement pain, range of postoperative knee joint motion(ROM),muscle strength of femoral quadriceps,incidence rates of adverse reaction within 7 days after operation,HSS score3 months before and after the operation,and discharge time were observed. Results Postoperative VIS score in CFNB group was lower than that in PCIA group.ROM and muscle strength of femoral quadriceps in CFBN group were better than those in PCIA group on day 1, 2, 3, 5, and 7 after the operation. Postoperative adverse reaction rate within 7 days in PCIA group was significantly higher than that in CFNB group. HSS score three months after the operation in CFNB group was higher than that in PCIA group. Discharge time of CFNB group was significantly earlier than that of PCIA group(P<0.05). Conclusion Compared with PCIA analgesia,CFNBanalgesia shows better analgesic effect. It can alleviate early knee joint pain after TKA, increase joint motion,significantly shorten the hospitalization time, promote joint exercises which are effective in functional rehabilitation, and decrease the incidence of adverse reactions like nausea and vomiting.
Objective To compare the early analgesic effects of continuous femoral nerve block analgesia(CFNB) and patient controlled intravenous analgesia(PCIA) and their effects on functional recovery after total knee arthroplasty. Methods Retrospective analysis was conducted on 60 ASA I and ASA II patients with unilateral total knee arthroplasty in our hospital from January 2014 to January 2015. The patients were divided into two groups,CFBN group(treatment group) and PCIA group(control group),with 30 patients in each group. VAS scores of postoperative ipsilateral knee resting and movement pain, range of postoperative knee joint motion(ROM),muscle strength of femoral quadriceps,incidence rates of adverse reaction within 7 days after operation,HSS score3 months before and after the operation,and discharge time were observed. Results Postoperative VIS score in CFNB group was lower than that in PCIA group.ROM and muscle strength of femoral quadriceps in CFBN group were better than those in PCIA group on day 1, 2, 3, 5, and 7 after the operation. Postoperative adverse reaction rate within 7 days in PCIA group was significantly higher than that in CFNB group. HSS score three months after the operation in CFNB group was higher than that in PCIA group. Discharge time of CFNB group was significantly earlier than that of PCIA group(P<0.05). Conclusion Compared with PCIA analgesia,CFNBanalgesia shows better analgesic effect. It can alleviate early knee joint pain after TKA, increase joint motion,significantly shorten the hospitalization time, promote joint exercises which are effective in functional rehabilitation, and decrease the incidence of adverse reactions like nausea and vomiting.
2016, 37(11): 70-75.
Abstract:
Objective To investigate the incidence and risk factors of urinary incontinence of the adult women in two communities in Kunming so as to obtain basic epidemiological data, draw epidemiological regularity of adult women urinary incontinence in this two communities. Methods International Consultation on Inconvenience Questionnaire Short Form(ICQ-SF) survey was conducted among adult women Shuanglongqiao community and Zongshuying community during April 2012 to April 2013. Results(1) The prevalence rate of urinary incontinence among adult women was 16.84%. The constituent ratio of stress urinary incontinence was 42.6%, mainly with mild occurrence. Women over 41 years old were found with moderate and severe urinary incontinences.(2) The prevalence of urinary incontinence increased with age, especially the middle-aged and elderly women. The incidence was related to educational background, occupation, marriage and pregnancy status, and history of pelvic surgery(P<0.05). Conclusion Urinary incontinence affects middle-aged and elderly women. There are differences of the prevalence of urinary incontinence among adult women with different nationality, occupation, educational background,marriage and pregnancy status, and history of pelvic surgery.
Objective To investigate the incidence and risk factors of urinary incontinence of the adult women in two communities in Kunming so as to obtain basic epidemiological data, draw epidemiological regularity of adult women urinary incontinence in this two communities. Methods International Consultation on Inconvenience Questionnaire Short Form(ICQ-SF) survey was conducted among adult women Shuanglongqiao community and Zongshuying community during April 2012 to April 2013. Results(1) The prevalence rate of urinary incontinence among adult women was 16.84%. The constituent ratio of stress urinary incontinence was 42.6%, mainly with mild occurrence. Women over 41 years old were found with moderate and severe urinary incontinences.(2) The prevalence of urinary incontinence increased with age, especially the middle-aged and elderly women. The incidence was related to educational background, occupation, marriage and pregnancy status, and history of pelvic surgery(P<0.05). Conclusion Urinary incontinence affects middle-aged and elderly women. There are differences of the prevalence of urinary incontinence among adult women with different nationality, occupation, educational background,marriage and pregnancy status, and history of pelvic surgery.
2016, 37(11): 76-81.
Abstract:
Objective To evaluate clinical value of ultrasound contrast agent the sulfur hexafluoride micro-bubble in the treatment of T2 WI high signal uterine fibroids with high intensity focused ultrasound(HIFU).Methods A total of 36 patients with T2 WI high signal uterine fibroids were randomly divided into experimental group and control group. Eighteen patients in experimental group received HIFU treatment with sulfur hexafluoride micro-bubble before, during and after the operation while another eighteen in control group received HIFU treatment with sulfur hexafluoride micro-bubble only after the operation. We recorded operation time(min),changing time of massive gray(s),irradiation time(s),therapeutic dose(J),incidence of complications and ablation rate(%). Results Operation time, changing time of massive gray, irradiation time,and therapeutic dose in experimental group were(101.51±43.02) min,(856.42±451.14) s,(1 077.37±546.23) s,and(496581.81 ±267192.31) J, respectively while those in control group were(261.34 ±85.53) min,(1833.32±642.67) s,(1 890.21±1 268.43) s,and(784 608.31±357 621.45) J,respectively. Significant differences were found among those parameters between the two groups(P <0.05). Tumor ablation rate in experimental group was 83.3% while that in control group was 55.5%, which was of significant difference between the two groups(P<0.05). One case of muscular stiffness was found in experimental group while one case of second-degree burn and two cases of muscular stiffness were found in the control group.The incidence of complications was 1/18(5.5%). No severe complication like bowel perforation or bladder perforation was found in the two groups. Conclusion The effect of ultrasound contrast agent sulfur hexafluoride micro-bubble can shorten operation time, improve tumor ablation rate and reduce complications and it can play a guiding role in clinical work.
Objective To evaluate clinical value of ultrasound contrast agent the sulfur hexafluoride micro-bubble in the treatment of T2 WI high signal uterine fibroids with high intensity focused ultrasound(HIFU).Methods A total of 36 patients with T2 WI high signal uterine fibroids were randomly divided into experimental group and control group. Eighteen patients in experimental group received HIFU treatment with sulfur hexafluoride micro-bubble before, during and after the operation while another eighteen in control group received HIFU treatment with sulfur hexafluoride micro-bubble only after the operation. We recorded operation time(min),changing time of massive gray(s),irradiation time(s),therapeutic dose(J),incidence of complications and ablation rate(%). Results Operation time, changing time of massive gray, irradiation time,and therapeutic dose in experimental group were(101.51±43.02) min,(856.42±451.14) s,(1 077.37±546.23) s,and(496581.81 ±267192.31) J, respectively while those in control group were(261.34 ±85.53) min,(1833.32±642.67) s,(1 890.21±1 268.43) s,and(784 608.31±357 621.45) J,respectively. Significant differences were found among those parameters between the two groups(P <0.05). Tumor ablation rate in experimental group was 83.3% while that in control group was 55.5%, which was of significant difference between the two groups(P<0.05). One case of muscular stiffness was found in experimental group while one case of second-degree burn and two cases of muscular stiffness were found in the control group.The incidence of complications was 1/18(5.5%). No severe complication like bowel perforation or bladder perforation was found in the two groups. Conclusion The effect of ultrasound contrast agent sulfur hexafluoride micro-bubble can shorten operation time, improve tumor ablation rate and reduce complications and it can play a guiding role in clinical work.
2016, 37(11): 82-85.
Abstract:
Objective To investigate the relationship between thyroid hormone and uric acid(UA) and body mass index(BMI) in patients with type II diabetes and normal thyroid function. Methods Total of 313 patients with type II diabetes and normal thyroid function were selected. BMI, fasting blood glucose(FBG),the metabolism of blood lipid, thyroid hormones and UA indicators were examined and the correlations of thyroid hormone,BMI and UA were analyzed.Results(1) The patients were divided into two groups according to gender,and FT3, FT4, and UA of male were found to be significantly higher than those in female(P<0.01). TSH,SBP,HDL-C in female were significantly higher than those in male(P<0.01);(2) The patients were divided into three groups according to BMI level. Thyroid-stimulating hormone(TSH),three iodine armour gland original glycine(TT3), free three iodine thyroid glycine(FT3), UA,and FBG in overweight and obesity groups were found to be higher than those in normal weight group(P < 0.05);(3) The patients were divided into two groups according to the TSH level. Serum uric acid,TT3,FT3,fasting insulin in the group with TSH above 2.5 u IU/L were found to be higher than those in the group with TSH under 2.5 u IU/L(P < 0.05);(4) Patients were divided into two groups according to the UA level. TSH, FT3 in male with high uric acid were found to be higher than those in male with normal uric acid(P < 0.05);TSH was in female with high uric acid was found to be higher than that in female with normal uric acid(P < 0.05). Conclusion Thyroid hormone in patients with type II diabetes can be used to assess the body weight and uric acid, which is of great clinical importance.
Objective To investigate the relationship between thyroid hormone and uric acid(UA) and body mass index(BMI) in patients with type II diabetes and normal thyroid function. Methods Total of 313 patients with type II diabetes and normal thyroid function were selected. BMI, fasting blood glucose(FBG),the metabolism of blood lipid, thyroid hormones and UA indicators were examined and the correlations of thyroid hormone,BMI and UA were analyzed.Results(1) The patients were divided into two groups according to gender,and FT3, FT4, and UA of male were found to be significantly higher than those in female(P<0.01). TSH,SBP,HDL-C in female were significantly higher than those in male(P<0.01);(2) The patients were divided into three groups according to BMI level. Thyroid-stimulating hormone(TSH),three iodine armour gland original glycine(TT3), free three iodine thyroid glycine(FT3), UA,and FBG in overweight and obesity groups were found to be higher than those in normal weight group(P < 0.05);(3) The patients were divided into two groups according to the TSH level. Serum uric acid,TT3,FT3,fasting insulin in the group with TSH above 2.5 u IU/L were found to be higher than those in the group with TSH under 2.5 u IU/L(P < 0.05);(4) Patients were divided into two groups according to the UA level. TSH, FT3 in male with high uric acid were found to be higher than those in male with normal uric acid(P < 0.05);TSH was in female with high uric acid was found to be higher than that in female with normal uric acid(P < 0.05). Conclusion Thyroid hormone in patients with type II diabetes can be used to assess the body weight and uric acid, which is of great clinical importance.
2016, 37(11): 86-88.
Abstract:
Objective To investigate the incidence of thyroid space occupying lesion by ultrasound imaging in patients with breast cancer. Methods From 2009 to 2012,150 patients with breast cancer as experimental group and another 150 patients with breast benign diseases as control group underwent thyroid ultrasound examination. Ultrasound results of the two groups were analyzed to find the differences. Result More obvious space occupying lesions were found in experimental group than those in control group(P<0.05). Conclusion The incidence rate of thyroid space occupying lesion in the patients with breast cancer is higher than that in the patients with no breast cancer.
Objective To investigate the incidence of thyroid space occupying lesion by ultrasound imaging in patients with breast cancer. Methods From 2009 to 2012,150 patients with breast cancer as experimental group and another 150 patients with breast benign diseases as control group underwent thyroid ultrasound examination. Ultrasound results of the two groups were analyzed to find the differences. Result More obvious space occupying lesions were found in experimental group than those in control group(P<0.05). Conclusion The incidence rate of thyroid space occupying lesion in the patients with breast cancer is higher than that in the patients with no breast cancer.
2016, 37(11): 89-92.
Abstract:
Objectives To explore the ultrasonic features in the differential diagnosis of thyroid multiple nodules with thyroid carcinoma and summarize the causes of misdiagnosis, and to improve the accuracy of ultrasonic diagnosis of thyroid carcinoma. Methods The ultrasound images from the 40 patients with thyroid carcinoma were selected,whose diagnosis of thyroid carcinoma was confirmed by the pathological examinations after surgery but misdiagnosed or not identified by ultrasound examination. These ultrasound images were retrospectively analyzed through observing the carcinomatous nodules in size,aspect ratio, shape, border, envelope, internal echo,calcification characteristics,posterior echo,acoustic halo, the distribution of blood flow, and the relationship with thyroid capsule and anterior organization,whether to transfer to neck or spraclavicular lymph nodes, and the performance of elasticity imaging, and then these features were compared with the ultrasonic features of the benign thyroid nodules. Results The ultrasonic features of thyroid multiple nodules with thyroid carcinoma were complicated and each nodule should be observed and analyzed individually. The ultrasonic features of carcinomatous nodules were:(1) irregular shape,(2)aspect ratio ≥1,(3)unclear border,(4)no capsule,(5)heterogeneous hypo echo inside of the carcinomatous nodules,(6)scattered distribution of clustered microcalcifications,(7)incomplete acoustic halo or absent,(8)blood supply to the centrality inside of the carcinomatous nodules,(9)invaded thyroid capsule and anterior organizations,(10)transformation to neck or supraclavicular lymph nodes in the minority of patients,(11) elasticity imaging score of 3 ~5. Conclusions It is quite difficult to identify the ultrasonic features of thyroid multiple nodules with thyroid carcinoma and it is with high misdiagnosis rate. A comprehensive analysis of sonographic features is essential in clinical practices, and it will contribute to improving the accuracy of the ultrasonic diagnosis of thyroid multiple nodules with thyroid carcinoma.
Objectives To explore the ultrasonic features in the differential diagnosis of thyroid multiple nodules with thyroid carcinoma and summarize the causes of misdiagnosis, and to improve the accuracy of ultrasonic diagnosis of thyroid carcinoma. Methods The ultrasound images from the 40 patients with thyroid carcinoma were selected,whose diagnosis of thyroid carcinoma was confirmed by the pathological examinations after surgery but misdiagnosed or not identified by ultrasound examination. These ultrasound images were retrospectively analyzed through observing the carcinomatous nodules in size,aspect ratio, shape, border, envelope, internal echo,calcification characteristics,posterior echo,acoustic halo, the distribution of blood flow, and the relationship with thyroid capsule and anterior organization,whether to transfer to neck or spraclavicular lymph nodes, and the performance of elasticity imaging, and then these features were compared with the ultrasonic features of the benign thyroid nodules. Results The ultrasonic features of thyroid multiple nodules with thyroid carcinoma were complicated and each nodule should be observed and analyzed individually. The ultrasonic features of carcinomatous nodules were:(1) irregular shape,(2)aspect ratio ≥1,(3)unclear border,(4)no capsule,(5)heterogeneous hypo echo inside of the carcinomatous nodules,(6)scattered distribution of clustered microcalcifications,(7)incomplete acoustic halo or absent,(8)blood supply to the centrality inside of the carcinomatous nodules,(9)invaded thyroid capsule and anterior organizations,(10)transformation to neck or supraclavicular lymph nodes in the minority of patients,(11) elasticity imaging score of 3 ~5. Conclusions It is quite difficult to identify the ultrasonic features of thyroid multiple nodules with thyroid carcinoma and it is with high misdiagnosis rate. A comprehensive analysis of sonographic features is essential in clinical practices, and it will contribute to improving the accuracy of the ultrasonic diagnosis of thyroid multiple nodules with thyroid carcinoma.
2016, 37(11): 93-96.
Abstract:
Objective To measure the dynamic and static frictional resistances between different self-ligating orthodontic brackets and different combination of tandem archwires. Methods On standard model the upper right quadrant Damon Q self-ligating brackets was pasted as team A, 3M Smart clip self-ligating brackets as team B and Forestadent Quick 3.0 self-ligating brackets as team C respectively. Nickel-titanium archwires of 0.012 inch and0.016 inch and two nickel-titanium archwires of 0.014 inch were applied to simulate sliding in the brackets and measure the friction changes in brackets and archwires, so as to explore the frictional resistance between different combination of the tandem archwires and different self-ligating brackets. Results When using the combination of two 0.014-inch nickel-titanium tandem archwires, the static frictional resistances was significantly different(P<0.05):team A
Objective To measure the dynamic and static frictional resistances between different self-ligating orthodontic brackets and different combination of tandem archwires. Methods On standard model the upper right quadrant Damon Q self-ligating brackets was pasted as team A, 3M Smart clip self-ligating brackets as team B and Forestadent Quick 3.0 self-ligating brackets as team C respectively. Nickel-titanium archwires of 0.012 inch and0.016 inch and two nickel-titanium archwires of 0.014 inch were applied to simulate sliding in the brackets and measure the friction changes in brackets and archwires, so as to explore the frictional resistance between different combination of the tandem archwires and different self-ligating brackets. Results When using the combination of two 0.014-inch nickel-titanium tandem archwires, the static frictional resistances was significantly different(P<0.05):team A
2016, 37(11): 97-100.
Abstract:
Objective To investigate clinical effects of bio-feedback and pelvic electric stimulation on stress urinary incontinence(SUI). Methods Fifty-six patients with SUI were selected randomly. All the patients received one or two courses of treatment and the effects were observed. Results Forty-three patients finished the treatment and the symptoms were improved. Scores of ICI-Q-SF and rotational angle of bladder were found to be significantly different from those before the treatment. Conclusions Stress urinary incontinence could be treated by bio-feedback and pelvic electric stimulation. Both the combination of treatment and individualized treatment should be taken into account.
Objective To investigate clinical effects of bio-feedback and pelvic electric stimulation on stress urinary incontinence(SUI). Methods Fifty-six patients with SUI were selected randomly. All the patients received one or two courses of treatment and the effects were observed. Results Forty-three patients finished the treatment and the symptoms were improved. Scores of ICI-Q-SF and rotational angle of bladder were found to be significantly different from those before the treatment. Conclusions Stress urinary incontinence could be treated by bio-feedback and pelvic electric stimulation. Both the combination of treatment and individualized treatment should be taken into account.
2016, 37(11): 101-104.
Abstract:
Objective To investigate the value of critical scoring system in the treatment of multiple organ dysfunction after exposure to poisoning by analyzing 3 cases of industrial organic fluorine gas poisoning. Methods Clinical data of symptoms,signs,treatments,outcome and the changes in the scores as APACHEⅡ,SOFA,MODS were collected,the differences among the patients were compared and the relevance was analyzed. Results The first APACHEⅡwas 19-26. Scores of case 1 in the three scoring systems constantly increased and different components were found, with the suggestion of sequential organ dysfunction. Other two patients' scores decreased and survived without complications. Conclusion Multiple critical scoring systems can be used to evaluate the outcome of multiple organ dysfunction due to organic fluorine gas poisoning. System evaluation and individualized treatment are both important. More studies can help to set up a special critical scoring system.
Objective To investigate the value of critical scoring system in the treatment of multiple organ dysfunction after exposure to poisoning by analyzing 3 cases of industrial organic fluorine gas poisoning. Methods Clinical data of symptoms,signs,treatments,outcome and the changes in the scores as APACHEⅡ,SOFA,MODS were collected,the differences among the patients were compared and the relevance was analyzed. Results The first APACHEⅡwas 19-26. Scores of case 1 in the three scoring systems constantly increased and different components were found, with the suggestion of sequential organ dysfunction. Other two patients' scores decreased and survived without complications. Conclusion Multiple critical scoring systems can be used to evaluate the outcome of multiple organ dysfunction due to organic fluorine gas poisoning. System evaluation and individualized treatment are both important. More studies can help to set up a special critical scoring system.
2016, 37(11): 105-109.
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Objective To discuss the injury mechanisms of posterior keen dislocation with anterior tibial plateau fracture and to provide theoretic support for clinic diagnosis and treatment. Methods Total of 25 cases with posterior knee dislocation and anterior tibial plateau fracture were enrolled from June,2009 to June,2012. Injury mechanisms were analyzed from the point of view of mechanics by combining with detailed histories,X-ray,CT scan and MRI results, and surgical findings.Results All of 25 cases were high-energy injury,with 13 falling from heights(about 2-5 meters),10 injured in traffic accident, 1 falling down by carrying heavy backpacks and 1rolling down hill. Posterior knee dislocation with the anterior tibial plateau fracture were found in all the 25 cases,among which 5 cases were with common peroneal nerve injury and popliteal artery rupture,and 1 case was with capitulum fibulae fracture and the rest were with no obvious artery nerve injury One years after operation,the average HSS score of the knee joint was 88.5 and the excellent and good rate was 93.7%. Conclusion The main reason of the backward dislocation of knee joint with the anterior border fracture of tibial plateau was high energy trauma and it was a new type of fracture-dislocation of knee joint. After backward dislocation of knee joint, we should carefully check whether there is the anterior-edge fracture of tibial plateau before operation to avoid misdiagnosis; reduction of the anterior-edge fracture of tibial plateau must be done Anatomically in operation,which can reduce the occurrence ofinstability of knee joint after operation and improve the operation effect
Objective To discuss the injury mechanisms of posterior keen dislocation with anterior tibial plateau fracture and to provide theoretic support for clinic diagnosis and treatment. Methods Total of 25 cases with posterior knee dislocation and anterior tibial plateau fracture were enrolled from June,2009 to June,2012. Injury mechanisms were analyzed from the point of view of mechanics by combining with detailed histories,X-ray,CT scan and MRI results, and surgical findings.Results All of 25 cases were high-energy injury,with 13 falling from heights(about 2-5 meters),10 injured in traffic accident, 1 falling down by carrying heavy backpacks and 1rolling down hill. Posterior knee dislocation with the anterior tibial plateau fracture were found in all the 25 cases,among which 5 cases were with common peroneal nerve injury and popliteal artery rupture,and 1 case was with capitulum fibulae fracture and the rest were with no obvious artery nerve injury One years after operation,the average HSS score of the knee joint was 88.5 and the excellent and good rate was 93.7%. Conclusion The main reason of the backward dislocation of knee joint with the anterior border fracture of tibial plateau was high energy trauma and it was a new type of fracture-dislocation of knee joint. After backward dislocation of knee joint, we should carefully check whether there is the anterior-edge fracture of tibial plateau before operation to avoid misdiagnosis; reduction of the anterior-edge fracture of tibial plateau must be done Anatomically in operation,which can reduce the occurrence ofinstability of knee joint after operation and improve the operation effect
2016, 37(11): 110-112.
Abstract:
Objective To evaluate the clinical indication, research value and surgical techniques of retroperitoneal laparoscopic ureter lithotomy for ureteral calculi. Methods Clinical data of 98 cases were retrospectively analyzed. All the patients underwent RLU, KWB, IVP, CTU or MRU examination and diagnosed with ureteral calculi, with 42 cases of upper ureteral calculi, 35 cases of middle ureteral calculi, and 21 cases of low ureteral calculi. Laparoscopic ureter lithotomy was performed on all the patients. Results All the 98 cases underwent laparoscopic ureter lithotomy(RLU) successfully, with the sizes of stones ranging from 1.5 to 3.0cm,the mean operative time 60 minutes(from 45 to 100 minutes), and mean blood loss 30 m L(from 20 to 60ml).Complication had not been observed in 85 cases for 3-38 months follow-up. Conclusions The treatment of ureteral calculi with lapa-endo-scopic ureter lithotomy shows its unique superiority on the basis of skilled operative technology. Lapa-endo-scopic ureter lithotomy can be a preferred method to be performed or be a compensation method in some cases.
Objective To evaluate the clinical indication, research value and surgical techniques of retroperitoneal laparoscopic ureter lithotomy for ureteral calculi. Methods Clinical data of 98 cases were retrospectively analyzed. All the patients underwent RLU, KWB, IVP, CTU or MRU examination and diagnosed with ureteral calculi, with 42 cases of upper ureteral calculi, 35 cases of middle ureteral calculi, and 21 cases of low ureteral calculi. Laparoscopic ureter lithotomy was performed on all the patients. Results All the 98 cases underwent laparoscopic ureter lithotomy(RLU) successfully, with the sizes of stones ranging from 1.5 to 3.0cm,the mean operative time 60 minutes(from 45 to 100 minutes), and mean blood loss 30 m L(from 20 to 60ml).Complication had not been observed in 85 cases for 3-38 months follow-up. Conclusions The treatment of ureteral calculi with lapa-endo-scopic ureter lithotomy shows its unique superiority on the basis of skilled operative technology. Lapa-endo-scopic ureter lithotomy can be a preferred method to be performed or be a compensation method in some cases.
2016, 37(11): 113-115.
Abstract:
Objective To investigate the clinical effects and feasibility of highly concentrated Potassium Chloride via central venous catheterization by micro pump on severe hypokalemia patients in EICU. Methods A totlal of 120 severe hypokalemia patients in our department were randomly divided into experimental group(treated with highly concentrated Potassium Chloride) and control group(normal treatment group) respectively, and treated with Potassium Chloride liquid of different concentration. Potassium levels in blood were checked every hour and the time for reaching standard potassium level(4.0mmol/L) and the total volumes of infusion fluid within 24 hours in the two groups was compared. Results The mean time for reaching standard potassium level and the total volumes of infusion fluid within 24 hours in the experimental group,(12.83±3.57) h and(402.56±54.61) ml respectively, were significantly less than those in the control group(P <0.01),(23.18 ±4.98) h and(2875.2 ±206.26) ml respectively. Conclusion Highly-concentrated potassium chloride injection via central venous catheterization by micro-pump is a safe, effective and feasible treatment on the patients with severe hypokalemia, especially on the patients with volume-overloaded heart and severe hypokalemia, which is worthy of further clinical research.
Objective To investigate the clinical effects and feasibility of highly concentrated Potassium Chloride via central venous catheterization by micro pump on severe hypokalemia patients in EICU. Methods A totlal of 120 severe hypokalemia patients in our department were randomly divided into experimental group(treated with highly concentrated Potassium Chloride) and control group(normal treatment group) respectively, and treated with Potassium Chloride liquid of different concentration. Potassium levels in blood were checked every hour and the time for reaching standard potassium level(4.0mmol/L) and the total volumes of infusion fluid within 24 hours in the two groups was compared. Results The mean time for reaching standard potassium level and the total volumes of infusion fluid within 24 hours in the experimental group,(12.83±3.57) h and(402.56±54.61) ml respectively, were significantly less than those in the control group(P <0.01),(23.18 ±4.98) h and(2875.2 ±206.26) ml respectively. Conclusion Highly-concentrated potassium chloride injection via central venous catheterization by micro-pump is a safe, effective and feasible treatment on the patients with severe hypokalemia, especially on the patients with volume-overloaded heart and severe hypokalemia, which is worthy of further clinical research.
2016, 37(11): 116-120.
Abstract:
Objective To summarize treatment experiences of microsurgical clipping for anterior communicating artery aneurysm via pterional approach. Methods Clinical data of 82 cases undergoing microsurgical clipping for anterior communicating artery aneurysm via pterional approach in the first affiliated hospital of Kunming Medical University from October 2008 to December 2014 were collected and retrospectively analyzed.The patients were divided into different groups by Hunt-Hess illness grading scale,with 11 cases for level 0,7cases for level I, 30 cases for level II, 25 cases for level III, 8 cases for level IV, and 1 cases for level V.Twenty-one patients underwent operation at early stage of SAH(≤3d),15 at late stage of SAH(4d~2W),and35 at prolonged stage of SAH(>2W). The prognosis of patients was evaluated according to GOS classification criteria at discharge.Results A total of 85 ACo AA were found in 82 patients and all of them were clipped and,at the same time, 3 aneurysms were resected and 11 thrombuses were punctured, cut and removed. In the operation, 15(17.6%) aneurysms ruptured again and temporary blocking happened for 73 times, with the shortest blocking time of 2 min, the longest of 40 min, and the average of 9.26 min. According to GOS score, good recovery rate was 79.3%(65/82), moderate disability rate was 12.2%(10/82), severe disability rate was 3.7%(3/82), vegetative state rate was 0%, and death rate was 4.9%(4/82). Good recovery rates for the operations at early, late and prolonged stage of SAH were 85.7%, 73.3% and 82.3% respectively and for level 0 to level V were90.9%, 85.6%, 86.7% and 84.0%, 25.0% and 0.0% respectively. Results of DSA or CTA re-examination upon55 patients followed-up at discharge or three months after discharge showed that tumor pedicle were clipped and aneurysm disappeared. Fifty cases were followed up from four months to seven years after the operation, with one case of aneurysm recurrence. Another thirty-two cases were lost to follow-up. Conclusions Microsurgical techniques and microdissection are keys to successful operation. Pterional approach can guarantee successful clipping of aneurysms with different directions, locations and sizes. It is also an easy, effective and reliable approach with less postoperative complications. Operation for anterior communicating artery aneurysm should be performed as early as possible.
Objective To summarize treatment experiences of microsurgical clipping for anterior communicating artery aneurysm via pterional approach. Methods Clinical data of 82 cases undergoing microsurgical clipping for anterior communicating artery aneurysm via pterional approach in the first affiliated hospital of Kunming Medical University from October 2008 to December 2014 were collected and retrospectively analyzed.The patients were divided into different groups by Hunt-Hess illness grading scale,with 11 cases for level 0,7cases for level I, 30 cases for level II, 25 cases for level III, 8 cases for level IV, and 1 cases for level V.Twenty-one patients underwent operation at early stage of SAH(≤3d),15 at late stage of SAH(4d~2W),and35 at prolonged stage of SAH(>2W). The prognosis of patients was evaluated according to GOS classification criteria at discharge.Results A total of 85 ACo AA were found in 82 patients and all of them were clipped and,at the same time, 3 aneurysms were resected and 11 thrombuses were punctured, cut and removed. In the operation, 15(17.6%) aneurysms ruptured again and temporary blocking happened for 73 times, with the shortest blocking time of 2 min, the longest of 40 min, and the average of 9.26 min. According to GOS score, good recovery rate was 79.3%(65/82), moderate disability rate was 12.2%(10/82), severe disability rate was 3.7%(3/82), vegetative state rate was 0%, and death rate was 4.9%(4/82). Good recovery rates for the operations at early, late and prolonged stage of SAH were 85.7%, 73.3% and 82.3% respectively and for level 0 to level V were90.9%, 85.6%, 86.7% and 84.0%, 25.0% and 0.0% respectively. Results of DSA or CTA re-examination upon55 patients followed-up at discharge or three months after discharge showed that tumor pedicle were clipped and aneurysm disappeared. Fifty cases were followed up from four months to seven years after the operation, with one case of aneurysm recurrence. Another thirty-two cases were lost to follow-up. Conclusions Microsurgical techniques and microdissection are keys to successful operation. Pterional approach can guarantee successful clipping of aneurysms with different directions, locations and sizes. It is also an easy, effective and reliable approach with less postoperative complications. Operation for anterior communicating artery aneurysm should be performed as early as possible.
2016, 37(11): 121-125.
Abstract:
Objective To compare the advantages and disadvantages of 3D BRAVO and TRICKS for detecting cerebral venous sinus thrombosis(CVST) and to explore the MR scanning methods on CVST. Methods A retrospective analysis was conducted on 40 patients who were diagnosed with CVST in the Fourth Affiliated Hospital of Kunming Medical University from January 2011 to June, 2014. All the patients underwent TRICKS scan and 3D BRAVO examination and were classified into 3 groups based on dural venous sinuses,deep cerebral vein and superficial cerebral vein. Detection rates of TRICKS and BRAVO were evaluated and the results were analyzed. Result Detection rates of dural venous sinuses by TRICKS and BRAVO were 98.0% and 100% respectively. Detection rates of deep cerebral vein were 92.9% and 100% respectively. No significant difference was found(P>0.05). Detection rates of superficial cerebral vein were 66.7% and 100% respectively. Significant difference was found between the two(P<0.05).Conclusion BRAVO technology can clearly demonstrate the details of CVST,especially in superficial cerebral vein. With the combination use of TRICKS sequences, it will be of higher diagnostic value.
Objective To compare the advantages and disadvantages of 3D BRAVO and TRICKS for detecting cerebral venous sinus thrombosis(CVST) and to explore the MR scanning methods on CVST. Methods A retrospective analysis was conducted on 40 patients who were diagnosed with CVST in the Fourth Affiliated Hospital of Kunming Medical University from January 2011 to June, 2014. All the patients underwent TRICKS scan and 3D BRAVO examination and were classified into 3 groups based on dural venous sinuses,deep cerebral vein and superficial cerebral vein. Detection rates of TRICKS and BRAVO were evaluated and the results were analyzed. Result Detection rates of dural venous sinuses by TRICKS and BRAVO were 98.0% and 100% respectively. Detection rates of deep cerebral vein were 92.9% and 100% respectively. No significant difference was found(P>0.05). Detection rates of superficial cerebral vein were 66.7% and 100% respectively. Significant difference was found between the two(P<0.05).Conclusion BRAVO technology can clearly demonstrate the details of CVST,especially in superficial cerebral vein. With the combination use of TRICKS sequences, it will be of higher diagnostic value.
2016, 37(11): 126-129.
Abstract:
Objective To compare the treatment effects between improved micro-laparoscopic hernia sac high ligation and traditional hernia sac high ligation. Methods Retrospective analysis was conducted. A total of 200 pediatric patients diagnosed with inguinal hernia in our hospital from 2013 to 2014,ranging in age from 8 months to14 years, were enrolled and divided into observational group and control group(n=100) The two groups received improved-micro-laparoscopic hernia sac high ligation and traditional hernia sac high ligation respectively. We recorded intraoperative blood loss, operative incision length and operation time during the operation, and hospitalization time,pain time and total cost after the operation. Recurrence rate and complication were followed up for 6 months. Treatment effects were compared between these two groups. Results Smaller incision length, less blood loss and postoperative pain, shorter operative time and hospitalization time and lower recurrence rate were found in observational group and they were of statistical significance(P<0.05). Conclusion Improved-microlaparoscopic hernia sac high ligation for pediatric inguinal hernia shows better treatment effect, lower recurrence rate and better prognosis and it is an ideal approach.
Objective To compare the treatment effects between improved micro-laparoscopic hernia sac high ligation and traditional hernia sac high ligation. Methods Retrospective analysis was conducted. A total of 200 pediatric patients diagnosed with inguinal hernia in our hospital from 2013 to 2014,ranging in age from 8 months to14 years, were enrolled and divided into observational group and control group(n=100) The two groups received improved-micro-laparoscopic hernia sac high ligation and traditional hernia sac high ligation respectively. We recorded intraoperative blood loss, operative incision length and operation time during the operation, and hospitalization time,pain time and total cost after the operation. Recurrence rate and complication were followed up for 6 months. Treatment effects were compared between these two groups. Results Smaller incision length, less blood loss and postoperative pain, shorter operative time and hospitalization time and lower recurrence rate were found in observational group and they were of statistical significance(P<0.05). Conclusion Improved-microlaparoscopic hernia sac high ligation for pediatric inguinal hernia shows better treatment effect, lower recurrence rate and better prognosis and it is an ideal approach.
2016, 37(11): 130-133.
Abstract:
Objective To investigate the HIV/AIDS knowledge,attitude and behavior among undergraduates from different universities in Kunming and to provide scientific basis for health education strategy. Methods Stratified random cluster sampling method was applied and an anonymous questionnaire was conducted in 879 first and second year students from three universities in Kunming(Kunming Medical University,Yunnan University and Yunnan Art Institute). Results Undergraduates from different universities in Kunming performed differently on cognition of HIV/AIDS knowledge. Cognitive level in Yunnan Art Institute was relatively low while no obvious difference was found in Kunming Medical University and Yunnan University. No significant difference in the attitude toward HIV/AIDS was found in the three universities. Differences were found in protective behaviors and attitudes on preventing HIV/AIDS infection among three universities. Conclusion There are different cognition on HIV/AIDS knowledge,attitude and behavior among undergraduates from different type universities in Kunming. Cognition on HIV/AIDS related knowledge is relatively weak among Art college students, who should be targeted to strengthen health education.
Objective To investigate the HIV/AIDS knowledge,attitude and behavior among undergraduates from different universities in Kunming and to provide scientific basis for health education strategy. Methods Stratified random cluster sampling method was applied and an anonymous questionnaire was conducted in 879 first and second year students from three universities in Kunming(Kunming Medical University,Yunnan University and Yunnan Art Institute). Results Undergraduates from different universities in Kunming performed differently on cognition of HIV/AIDS knowledge. Cognitive level in Yunnan Art Institute was relatively low while no obvious difference was found in Kunming Medical University and Yunnan University. No significant difference in the attitude toward HIV/AIDS was found in the three universities. Differences were found in protective behaviors and attitudes on preventing HIV/AIDS infection among three universities. Conclusion There are different cognition on HIV/AIDS knowledge,attitude and behavior among undergraduates from different type universities in Kunming. Cognition on HIV/AIDS related knowledge is relatively weak among Art college students, who should be targeted to strengthen health education.
2016, 37(11): 134-138.
Abstract:
Objective To investigate influencing factors of disability after craniocerbral injury caused by road traffic accident. Methods We collected 486 cases with craniocerebral injury caused by traffic accident, and conducted analysis. Factors related to disability were found by univariate analysis, and multivariate logistic regression analysis was conducted to filter the most important factors. Results Degrees of brain injury, drunk driving, age and types of accident were the major influencing factors. Drunk driving and age were positively related with disability grade while the degree of brain injury and type of accident were negatively related. Conclusion It is helpful to reduce disability and the burden on society by taking intervening measures on the related factors of disability after brain injury in road traffic accident
Objective To investigate influencing factors of disability after craniocerbral injury caused by road traffic accident. Methods We collected 486 cases with craniocerebral injury caused by traffic accident, and conducted analysis. Factors related to disability were found by univariate analysis, and multivariate logistic regression analysis was conducted to filter the most important factors. Results Degrees of brain injury, drunk driving, age and types of accident were the major influencing factors. Drunk driving and age were positively related with disability grade while the degree of brain injury and type of accident were negatively related. Conclusion It is helpful to reduce disability and the burden on society by taking intervening measures on the related factors of disability after brain injury in road traffic accident
2016, 37(11): 139-141.
Abstract:
Objective To compare the difference between traditional model teaching method and the system of internal circulation system with high simulation of the teaching method of the teaching method of the arm of the arm of the intravenous infusion in children.Methods The research objects were taken as the research object, and the model of the arm of the 2013 students in Kunming college was taken as the research object,and the traditional model was the control group. The difference between the two groups were compared between the 100 groups.Results Compared with the control group,the study group's practice skill score(87.8 ± 6.9) points was higher than that in the control group(78.5 ± 7.4)(P <0.05);the teaching cost(2.64 ± 0.4 yuan) was higher than that in the control group(12.89±0.6 yuan)(P <0.05);the success rate of puncture in the study group 82.8% was higher than that in the control group(62.3%)(P <0.05).Conclusion The internal circulation system of high simulation of pediatric intravenous infusion arm model teaching method in basic nursing practice teaching can improve the teaching effect,the students teaching goal,and mobilize the enthusiasm of students learning.
Objective To compare the difference between traditional model teaching method and the system of internal circulation system with high simulation of the teaching method of the teaching method of the arm of the arm of the intravenous infusion in children.Methods The research objects were taken as the research object, and the model of the arm of the 2013 students in Kunming college was taken as the research object,and the traditional model was the control group. The difference between the two groups were compared between the 100 groups.Results Compared with the control group,the study group's practice skill score(87.8 ± 6.9) points was higher than that in the control group(78.5 ± 7.4)(P <0.05);the teaching cost(2.64 ± 0.4 yuan) was higher than that in the control group(12.89±0.6 yuan)(P <0.05);the success rate of puncture in the study group 82.8% was higher than that in the control group(62.3%)(P <0.05).Conclusion The internal circulation system of high simulation of pediatric intravenous infusion arm model teaching method in basic nursing practice teaching can improve the teaching effect,the students teaching goal,and mobilize the enthusiasm of students learning.
2016, 37(11): 142-144.
Abstract:
Objective To investigate the pressing time and puncture site bleeding after extubation of superficial venous catheter in elderly patients. Methods Four hundred elderly inpatients were selected from respiratory department during June 2015 and December 2015 and were divided into two groups: 200 patients as experimental group with pressing time of 5-6 minutes and 200 patients as control group with pressing time of 3-4minutes. The same group of nurses pressed the puncture site after extubation and changes on skin and vessels were observed, which was to find out the optimal pressing time after extubation of superficial venous catheter in elderly patients. Results The presence of bleeding,bruising,success rate of the second puncture,swelling, pain and degree of comfort were compared between two groups and significant differences were found(P<0.05). Conclusion Compared with those in control group,less bleeding,bruising,swelling,and pain,higher success rate of the second puncture and lower degree of comfort were found in experimental group.
Objective To investigate the pressing time and puncture site bleeding after extubation of superficial venous catheter in elderly patients. Methods Four hundred elderly inpatients were selected from respiratory department during June 2015 and December 2015 and were divided into two groups: 200 patients as experimental group with pressing time of 5-6 minutes and 200 patients as control group with pressing time of 3-4minutes. The same group of nurses pressed the puncture site after extubation and changes on skin and vessels were observed, which was to find out the optimal pressing time after extubation of superficial venous catheter in elderly patients. Results The presence of bleeding,bruising,success rate of the second puncture,swelling, pain and degree of comfort were compared between two groups and significant differences were found(P<0.05). Conclusion Compared with those in control group,less bleeding,bruising,swelling,and pain,higher success rate of the second puncture and lower degree of comfort were found in experimental group.
2016, 37(11): 145-148.
Abstract:
Objective To investigate the effects of continuous nursing quality improvement on emergency care of parturient with preeclampsia. Methods The parturient with preeclampsia in the First Affiliated Hospital of the Medical University Of Anhui from January 2010 to December 2015 were chosen. The effects of continuous nursing quality improvement on the emergency care of those parturient were analyzed and the maternal and infant health outcomes and patient satisfaction were contrasted. Results The surgical complication rate of the observation group patients was significantly lower than that of the control group(P<0.001). The overall health outcome of maternal and infant patients in the observation group was significantly better than that of the control group(P<0.000).Patient satisfaction of the observation group was significantly higher than that of the control group(P<0.000).Conclusion Continuous nursing quality improvement model can not only ensure the quality of eclampsia patient care but also keep on improving the care quality so as to improve maternal and infant health outcomes and patient satisfaction.
Objective To investigate the effects of continuous nursing quality improvement on emergency care of parturient with preeclampsia. Methods The parturient with preeclampsia in the First Affiliated Hospital of the Medical University Of Anhui from January 2010 to December 2015 were chosen. The effects of continuous nursing quality improvement on the emergency care of those parturient were analyzed and the maternal and infant health outcomes and patient satisfaction were contrasted. Results The surgical complication rate of the observation group patients was significantly lower than that of the control group(P<0.001). The overall health outcome of maternal and infant patients in the observation group was significantly better than that of the control group(P<0.000).Patient satisfaction of the observation group was significantly higher than that of the control group(P<0.000).Conclusion Continuous nursing quality improvement model can not only ensure the quality of eclampsia patient care but also keep on improving the care quality so as to improve maternal and infant health outcomes and patient satisfaction.
