2022 Vol. 43, No. 2

Original Articles Basic of Medicine
The Spation-temporal Expression of SOX9 during the Development of Mandibular Condylar Cartilage and Tibial Growth Plate Cartilage in SD Rats
Rui MAO, Ying HE, Zichao DAI, Song LI
2022, 43(2): 1-6. doi: 10.12259/j.issn.2095-610X.S20220210
Abstract(2357) HTML PDF(52)
Abstract:
Objective To explore the spation-temporal expression changes of SOX9during the development of condylar cartilage and tibial growth plate cartilage in SD rats. Methods Thirty adult SD rats were caged at the female-male ratio of 2∶1. The vaginal plug ...
Effects of Different Accumulation Culture Methods on the Titer of Phage PEf771
Rongyu YANG, Fei SONG, Yunlin WEI, Xianghong YANG, Kaiwen Duan, Yingying XIANG
2022, 43(2): 7-11. doi: 10.12259/j.issn.2095-610X.S20220218
Abstract(2201) HTML PDF(42)
Abstract:
Objective To compare the effects of three different enriching culture methods on the titer of phage PEf771, and discuss the methods to effectively improve the titer of phage PEf771. Methods Through phage PEf771/E. faecalis YN771 proportional method,...
Effect of Surface Topography on Staphylococcus Epidermidis Biofilm Formation by Different 3D Printing Thickness of Biomaterials
Zhenghong YANG, Mingjie NING, Daqian HE, Mengzhe YANG, Yongping HUANG, Yunchao HUANG
2022, 43(2): 12-17. doi: 10.12259/j.issn.2095-610X.S20220228
Abstract(2758) HTML PDF(14)
Abstract:
Objective To investigate the effect of surface topography on staphylococcus epidermidis biofilm formation by different 3D printing Thickness of biomaterials. Methods Medical 3D printing raw material, photosensitive resin MED610 was used as the mate...
Establishment of Spinal Cord Ischemia Injury Model in Rats by Thoracic Aorta Occlusion Combined with Aortic Bypass
Ke YANG, Junjie FEI, Yuyin DUAN, Xin LI, Zhongcheng WU, Yingshan HUANG
2022, 43(2): 18-22. doi: 10.12259/j.issn.2095-610X.S20220217
Abstract(3522) HTML PDF(20)
Abstract:
Objective To modify the rat model of spinal cord ischemia injury. Methods The rats were divided into three groups. In experimental group, thoracic aorta was cross-clamped between T4 and T11, and aortic bypass circulation was established from proxima...
miR-145 Regulates the Expression of OCT4 in Human Endometrial Stromal Cells and Promotes the Development of Endometriosis
Suxian ZHANG, Limei FENG, Lu WU, Shaoyan YANG, Qinghua ZHAO
2022, 43(2): 23-33. doi: 10.12259/j.issn.2095-610X.S20220220
Abstract(3381) HTML PDF(25)
Abstract:
Objective To further explore the regulatory mechanism of miR-145 in Endometriosis (EMs) through cell experiments. Methods miR-145 or octamer-binding transcription factor 4 (OCT4)gene and protein expression levels in cells were examined using reverse ...
Two-dimensional Speckle Tracking Technology in the Study of Acute Myocardial Injury Caused by Anthracyclines
Jieqing MIN, Jinrun TIAN, Jiwei LI, lizheng WEI, Peng WANG, Yanjie CAO, Wenji HE, Mao FAN, Qian ZHANG, Yunjuan YANG
2022, 43(2): 34-38. doi: 10.12259/j.issn.2095-610X.S20220211
Abstract(4339) HTML PDF(18)
Abstract:
Objective To study the characteristics of left ventricular strain and myocardial pathological changes in acute myocardial injury induced by anthracyclines in Diannan small-ear pigs. Methods Six small-eared pigs from southern Yunnan were selected. Af...
Orthogonal Experiment for Optimization of Ultrasonic Extraction Process of Six Components from Geranium wilfordii Maxim
Kongchun SUN, Canyu YANG, Hongbo Zhang, Baochun SHEN
2022, 43(2): 39-46. doi: 10.12259/j.issn.2095-610X.S20220213
Abstract(2546) HTML PDF(33)
Abstract:
Objective T o optimize the ultrasonic extraction method for Geraniin, Gallic acid, Corilagin, Hyperoside, Ellagic acid, Protocatechuic acid from Geranium wilfordii Maxim by L9(34) orthogonal experiment. Methods On the basis of single factor experime...
miR-142-5p Regulates the Proliferation and Metastasis of Gallbladder Carcinoma Cells through CCND1
Baoquan WANG, Wei ZHANG, Yuan TIAN, Xifeng LEI, Xu WANG
2022, 43(2): 47-53. doi: 10.12259/j.issn.2095-610X.S20220223
Abstract(4046) HTML PDF(26)
Abstract:
Objective To explore the effect of miR-142-5p on the proliferation and metastasis of gallbladder cancer through CCND1 and to clarify the special mechanism of action. Methods RT-qPCR was performed to identify the differential expression of miR-142-5p...
Investigation and Analysis on Health Literacy of Students in a Medical College in Yunnan Province
Weimin GAO, Xin PU
2022, 43(2): 54-59. doi: 10.12259/j.issn.2095-610X.S20220227
Abstract(3418) HTML PDF(29)
Abstract:
Objective To understand the health literacy of medical college students in Yunnan Province and to analyze its influencing factors, so as to provide basis and targeted strategies for future interventions. Methods Random cluster sampling method was u...
Clinical Research
EGFR Gene Mutation State and Its Clinical Significance in Multi-nodular Lung Adenocarcinoma in Yunnan Province
Maofang WU, Yongchun ZHOU, Jingjing CAI, Xin MO, Yinwei LI, Jiahui MAO
2022, 43(2): 60-66. doi: 10.12259/j.issn.2095-610X.S20220215
Abstract(4006) HTML PDF(22)
Abstract:
Objective To investigate the relationship between EGFR gene mutations and clinicopathological characteristics of patients with multinodular lung adenocarcinoma in Yunnan province by using NGS method. Methods A total of 111 pulmonary nodule samples f...
Diagnostic Value of Guidewire Localization of Breast Mass Based on High-frequency Ultrasound Guidance in Breast Lesions
Xin WU, Pin-fei ZOU, Min HUANG
2022, 43(2): 67-71. doi: 10.12259/j.issn.2095-610X.S20220216
Abstract(4642) HTML PDF(22)
Abstract:
Objective To evaluate the diagnostic value of high-frequency ultrasound-guided guide wire localization of breast mass in patients with breast lesions. Methods Ninety patients with suspected breast mass lesions in Yunnan Hospital of Traditional Chine...
Changes of Thyroid Function and Its Clinical Significance before and after Radiotherapy and Chemotherapy in Patients Undergoing Radical Breast Cancer Treatment
Jiawei LIAO, Xiaoqing HU, Yi YANG
2022, 43(2): 72-77. doi: 10.12259/j.issn.2095-610X.S20220229
Abstract(4292) HTML PDF(25)
Abstract:
Objective To analyze the changes of thyroid function and its clinical significance after chemotherapy and radiotherapy in patients undergoing radical surgery for breast cancer. Methods One hundred and six patients admitted to Yunnan Cancer Hospital ...
Correlation between Neutrophil-lymphocyte Ratio and Disease Activity in 536 Patients with Systemic Lupus Erythematosus
Lihua MA, Xiangyu WANG, Yifan YANG, Ruotong ZHAO, Xiaoyan FENG, Jian XU
2022, 43(2): 78-81. doi: 10.12259/j.issn.2095-610X.S20220209
Abstract(2752) HTML PDF(26)
Abstract:
Objective To assess the correlation between neutrophil-lymphocyte ratio (NLR) and the disease activity of systemic lupus erythematosus (SLE). Methods A total of 536 patients with SLE from the Department of Rheumatology and Immunology of the First Af...
Comparison of the Efficacy of Double Plates and Locking Plates in the Treatment of Complex Proximal Humerus Fractures
Jin JIA, Xiaotao LU, Shun MENG, Yongcheng DENG, Yihao LEI, Kaiyu HOU
2022, 43(2): 82-88. doi: 10.12259/j.issn.2095-610X.S20220206
Abstract(3460) HTML PDF(14)
Abstract:
Objective To compare the clinical efficacy of double plates and locking plates in the treatment of complex proximal humerus fractures. Methods Fifty-seven patients admitted to the Department of Bone and Trauma Surgery of the Fourth Affiliated Hospit...
Potential Value of G6PD Activity Detection in the Peripheral Blood for the Diagnosis and Prognosis of Cervical Cancer Patients with High Risk Human Papillomavirus Infection
Honglan CHEN, Yi WU, Tao HU, Yuming WANG
2022, 43(2): 89-95. doi: 10.12259/j.issn.2095-610X.S20220203
Abstract(3930) HTML PDF(13)
Abstract:
Objective To explore the value of detecting G6PD activity in the peripheral blood for the diagnosis and prognosis of cervical cancer patients with high-risk human papillomavirus (HR-HPV) infection. Methods A total of 53 cervical cancer (CC) patients...
Relationship between the MTHFR C677T Gene Polymorphism and the Collateral Circulation in Patients with Carotid Stenosis
Liya ZHANG, Juan BAO, Jiaping WANG, Yi CAO, Ri JING, Lei ZHANG, Wenqing ZHANG, Tianyi LI
2022, 43(2): 96-101. doi: 10.12259/j.issn.2095-610X.S20220219
Abstract(3169) HTML PDF(9)
Abstract:
Objective To study the relationship between the MTHFR C677T gene polymorphism and the collateral circulation in patients with carotid stenosis. Methods A total of 65 patients with moderate or severe carotid stenosis and chronic occlusion diagnosed ...
Study on Microbiome of Supragingival Plaque of College Students with Gingivitis
Xinyi LI, Yuexiao LI, Lixian LI, Yongping LI, Ying GAO, Yanhong LI
2022, 43(2): 102-106. doi: 10.12259/j.issn.2095-610X.S20220207
Abstract(3295) HTML PDF(34)
Abstract:
Objective To compare the microbial differences of supragingival plaque between healthy gingiva group and gingivitis group of college students by high-throughput sequencing technology. Methods According to inclusion and exclusion criteria, 30 college...
Effect of Repairing Patellar Cartilage Fracture with Suture Anchor
Min YU, Ke CHOU, Yujia LI
2022, 43(2): 107-111. doi: 10.12259/j.issn.2095-610X.S20220202
Abstract(3196) HTML PDF(23)
Abstract:
Objective To study the effect of repairing patellar cartilage fracture with the suture anchor. Methods Between July 2016 and June 2018, 50 patients with patellar cartilage fracture were chosen, 18 male and 32 female, age 17 to 28. All of them were a...
Analysis about Pregnancy Outcome and Combined Treatment of Kangfuyan Capsule after Hysterolaparoscopy in Salpingemphraxis Infertility
Fang LUO, Yangyang LIAN, Xia LI, Huanhuan SHEN, Hongwen HU, Yin LI
2022, 43(2): 112-117. doi: 10.12259/j.issn.2095-610X.S20220201
Abstract(4848) HTML PDF(25)
Abstract:
Objective To explore the effect of Kangfuyan capsule combined with hysteroscopy in the treatment of recanalization of fallopian tube after sterilization, and to analyze the effect of combined therapy on pregnancy rate. Methods A retrospective analy...
Correlation of Lung Function and HRCT Bronchial Wall Thickness in Patients with Chronic Obstructive Pulmonary Disease
Qian HUANG, Meihua LI, Xiaojing TANG, Wei MA, Yanxia YANG, Qingling ZHENG, Jin HE
2022, 43(2): 118-121. doi: 10.12259/j.issn.2095-610X.S20220224
Abstract(3968) HTML PDF(26)
Abstract:
Objective To investigate the correlation of pulmonary function indexes and bronchial wall thickness measured as computed with high resolution computed tomography in patients with chronic obstructive pulmonary diseases. Methods Eighty COPD patients w...
The Correlation between AMH Levels in Serum and Follicular Fluid and the Number of Retrieved Oocytes During COH
Yunyan CHEN, Jinfeng CAI, Xinxin CHEN, Rongfang HUANG, Long LI, Dejiang ZHOU, Yuansong YU
2022, 43(2): 122-127. doi: 10.12259/j.issn.2095-610X.S20220204
Abstract(2535) HTML PDF(14)
Abstract:
Objective To study the dynamic changes of serum AMH during different periods of treatment in patients who received the treatment of controlled ovarian hyperstimulation (COH) and to observe the correlation between AMH level in large and medium follicu...
Impact of Acute Non-normovolemic Hemodilution on Perioperative NK Cell, NKT cell and Th1/Th2 in Elderly Patients Undergoing Rectal Carcinoma Radical Resection
Yiyin QU, Siyuan ZHENG, Chunyu DAI, Yi ZHANG
2022, 43(2): 128-133. doi: 10.12259/j.issn.2095-610X.S20220225
Abstract(2985) HTML PDF(8)
Abstract:
Objective To investigate the impact of acute non-normovolemic hemodilution (ANIH) on the numbers of NK cell, the NK cell cytotoxicity, numbers of NKT cell and the ratio of Th1 /Th2 cytokines in elderly patients undergoing rectal carcinoma radical res...
Clinical Application of Laparoscopic Cholecystectomy with Fluorescence Cholangiography of Indocyanine Green in the Difficult Cholecystectomy
Cheng ZHANG, Ning XU, Weisi LI, Yuntao ZHU, Min SUN
2022, 43(2): 134-140. doi: 10.12259/j.issn.2095-610X.S20220222
Abstract(3589) HTML PDF(21)
Abstract:
Objective To study the safety, feasibility and reliability of indocyanine green fluorescence staining in laparoscopic cholecystectomy, whether it can effectively avoid bile duct injury, and to explore the shortcomings and advantages of indocyanine gr...
Risk Factors of Aspiration Pneumonia Secondary to Swallowing Dysfunction after Stroke
Jing WANG, Zhenzhen ZHU, Yuxuan BAI, Zhibin JIA, Yanlong REN
2022, 43(2): 141-144. doi: 10.12259/j.issn.2095-610X.S20220214
Abstract(4096) HTML PDF(19)
Abstract:
Objective To study the risk factors and intervention methods of secondary aspiration and aspiration pneumonia caused by swallowing dysfunction after stroke. Methods The patients with dysphagia after stroke were divided into observation group and con...
Reviews
Role of α7-nicotinic Acetylcholine Receptor in Occurrence,Development and Therapy of Lung Cancer
Qiao LUO, Hong SHI, Shaobo WANG
2022, 43(2): 145-149. doi: 10.12259/j.issn.2095-610X.S20220226
Abstract(3589) HTML PDF(23)
Abstract:
Nicotinic acetylcholine receptors (nAChRs) are the central regulators of stimulatory and inhibitory neurotransmitters that control the synthesis and release of growth,angiogenic and neurotrophic factors incancer cells, the cancer microenvironment and...
Research Progress of Exosomal miRNA in Hepatocellular Carcinoma
Tianhong ZHANG, Hongju YANG
2022, 43(2): 150-153. doi: 10.12259/j.issn.2095-610X.S20220221
Abstract(3882) HTML PDF(36)
Abstract:
Exosomes are vesicle bodies secreted by different cells, which promote the occurrence and development of liver cancer through various mechanisms.At present, studies on the role of exosomal miRNA in liver cancer have aroused wide attention.According t...
AIDS Research
Prevalence of Kidney Disease among Pre-ART Patients with HIV Infection in Kunming and The Influencing Factors
Chongxi LI, Guangfeng YIN, Yushu ZHANG, Shanqun GU, Wei ZHANG, Jun LIU, Bo TIAN
2022, 43(2): 154-159. doi: 10.12259/j.issn.2095-610X.S20220208
Abstract(3699) HTML PDF(14)
Abstract:
Objective To investigate the prevalence and characteristics of nephropathy in HIV infected patients before antiviral treatment, and to analyze the related factors of nephropathy before antiviral treatment. Methods Patients with HIV infection who visi...
Nursing Forum
Application of Cluster Nursing based on Risk Assessment in Prevention of Deep Vein Thrombosis of Lower Extremity after Total Hysterectomy
Juli SHEN, Huifang JIA, Mei GAO, Jinmei DUAN, Ping LIU, Zuyan SUN, Huixian LIN
2022, 43(2): 160-165. doi: 10.12259/j.issn.2095-610X.S20220212
Abstract(3676) HTML PDF(10)
Abstract:
Objective To explore the cluster nursing for preventing deep vein thrombosis of lower extremity after total hysterectomy for benign gynecological diseases. Methods A total of 90 patients with benign gynecological diseases after total hysterectomy fr...
Influence of Internet Health System on HAMA,HAMD,SCHFI Score and SF-36 Score of Stroke Patients
Lin FANG, Xiaopeng LI
2022, 43(2): 166-170. doi: 10.12259/j.issn.2095-610X.S20220205
Abstract(2176) HTML PDF(14)
Abstract:
Objective To analyze the impact of the “Internet health system” on the HAMA, HAMD, SCHFI score and SF-36 score in stroke patients. Methods A total of 150 stroke patients were included in this study. They were divided into two groups according to the...