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RSS2022 Vol. 43, No. 3
2022, 43(3): 1-6.
doi: 10.12259/j.issn.2095-610X.S20220303
Abstract:
Objective To investigate the expression and clinical significance of PDE4D in ovarian cancer by excavating gene information in Oncomine and explore the effect of sanguinarine on PDE4D by cells experiment. Methods PharmMapper was used to find the tar...
2022, 43(3): 7-12.
doi: 10.12259/j.issn.2095-610X.S20220327
Abstract:
Objective To screen the pathogenic mutations in the four generations of a proband with atrial septal defect, so as to analyze the relationship between genotype and phenotype by whole exon sequencing and Sanger sequencing. Methods Retrospectic analys...
2022, 43(3): 13-20.
doi: 10.12259/j.issn.2095-610X.S20220317
Abstract:
Objective To explore the potential mechanism of thioridazine in the treatment of cervical cancer by bioinformatics analysis. Methods The target genes that can interact with thioridazine was predicted by PharmMapper, and then conducted pathway and ti...
2022, 43(3): 21-26.
doi: 10.12259/j.issn.2095-610X.S20220320
Abstract:
Objective To explore effect of the Willed movement on behaviours of rats with focal cerebral ischemia and the expression of GluA2 and N-cadherin in the brain tissue around ischemia. Methods We selected clean-level healthy male SD rats, and prepared ...
Genetics Analysis in a Congenital Cataract Pedigree Associated with a Missense Mutation in GJA8 gene
2022, 43(3): 27-31.
doi: 10.12259/j.issn.2095-610X.S20220305
Abstract:
Objective To analyze the clinical manifestations in a congenital cataract pedigree and the genetic etiology was identified using exon sequencing. Methods A family with congenital cataract admitted to the Second Affiliated Hospital of Kunming Medical...
2022, 43(3): 32-36.
doi: 10.12259/j.issn.2095-610X.S20220307
Abstract:
Objective To screen out the best method of PEG6000 modified liposomes for influenza vaccine and evaluate its stability. Methods After 7 d of immunization, the optimal molar percentage of PEG6000 and the optimal preparation method were assumed by MTT...
2022, 43(3): 37-43.
doi: 10.12259/j.issn.2095-610X.S20220310
Abstract:
Objective To develop a special module of PRO-IBD for patients with inflammatory bowel disease in China , so as to construct a complete digestive system scale. Methods The interview and questionnaire data of 32 gastroenterologists and 69 IBD patients ...
2022, 43(3): 44-49.
doi: 10.12259/j.issn.2095-610X.S20220319
Abstract:
Objective To study the correlation between attention and motor function in children with spastic hemiplegia. Methods A small sample cross-sectional observational study was conducted. Spearman correlation analysis was used to statistically analyze t...
2022, 43(3): 50-54.
doi: 10.12259/j.issn.2095-610X.S20220313
Abstract:
Objective To explore the feasibility of short-term indwelling urete in patients aftert PKEP （transurethral plasmamakinetic enucleation surgery）. Methods We performed a retrospective analysis of the clinical data of 89 patients with benign prostatic ...
2022, 43(3): 55-59.
doi: 10.12259/j.issn.2095-610X.S20220318
Abstract:
Objective To explore the risk factors of lymph node metastasis in patients with gallbladder cancer, and to provide references for comprehensive treatment and prognosis evaluation of gallbladder cancer. Methods We retrospectively analyzed the clinica...
2022, 43(3): 60-66.
doi: 10.12259/j.issn.2095-610X.S20220312
Abstract:
Objective To evaluate the reliability, validity and responsiveness of Patient Reported Outcome Instruments System for Chronic Disease-Hypertension, PROISCD-HY （V1.0）, a scale for measuring reported outcomes in patients with hypertension. Methods Dur...
2022, 43(3): 67-73.
doi: 10.12259/j.issn.2095-610X.S20220306
Abstract:
Objective To investigate the relationship between T950C polymorphism in the promoter region of osteoprotegerin （OPG） gene and type 2 diabetes mellitus （T2DM） complicated with osteoporosis, and to understand the genetically related susceptibility gene...
2022, 43(3): 74-79.
doi: 10.12259/j.issn.2095-610X.S20220322
Abstract:
Objective To explore the value of VI-RADS scoring system in predicting preoperative for invasive bladder cancer. Methods The MRI data of 320 cases of bladder cancer were retrospectively analyzed by the VI-RADS scoring system, T2WI, DWI and DCE-MRI w...
2022, 43(3): 80-85.
doi: 10.12259/j.issn.2095-610X.S20220311
Abstract:
Objective To observe the clinical efficacy of external radiative shock wave combined with sodium hyaluronate injection in the treatment of knee osteoarthritis （KOA）. Methods Sixty-two patients with KOA be divided into observation group and control g...
2022, 43(3): 86-93.
doi: 10.12259/j.issn.2095-610X.S20220301
Abstract:
Objective To study the salivary predominant bacteria in 5-year-old Lisu children with and without dental caries in Yunnan Province and to analyze the differences with local Han children. Methods 20 Lisu children with high caries （dmfs≥6） and 20 chi...
2022, 43(3): 94-97.
doi: 10.12259/j.issn.2095-610X.S20220326
Abstract:
Objective To analyze the detection of human cytomegalovirus （HCMV） DNA in different types of samples from pregnant women and infants. Methods From May 2021 to October, a total of 2403 clinical samples were collected. Fluorescence quantitative PCR to...
2022, 43(3): 98-102.
doi: 10.12259/j.issn.2095-610X.S20220308
Abstract:
Objective To compare the effects of hydromorphone and sufentanil on early postoperative cognitive function in patients with colorectal cancer. Methods Eighty-five patients with selective radical resection of colorectal cancerr （including laparoscopi...
2022, 43(3): 103-107.
doi: 10.12259/j.issn.2095-610X.S20220323
Abstract:
Objective To investigate the effect of parent administered physical therapy in the preterm period on motor performance in infants. Methods This study included 153 infants, 97 preterm infants and 56 term infants （term control group）. The preterm infa...
2022, 43(3): 108-112.
doi: 10.12259/j.issn.2095-610X.S20220325
Abstract:
Objective To understand and analyze the epidemiological characteristics of pre-hospital emergency patients in Kunming, so as to provide basis for optimizing the allocation of pre-hospital emergency resources. Methods Data of patients in Yunnan Emerg...
2022, 43(3): 113-122.
doi: 10.12259/j.issn.2095-610X.S20220321
Abstract:
Objective To evaluate the value of multimodal ultrasound in monitoring renal function and postoperative complications of DBD transplantation. Methods 67 cases of brain dead organ donor kidney transplantation （DBD） in Ganmei Hospital Affiliated to Ku...
2022, 43(3): 123-127.
doi: 10.12259/j.issn.2095-610X.S20220309
Abstract:
Objective To analyze the changes of intestinal flora in children with functional constipation （FC） and the clinical significance of non-pharmacological basic treatment. Methods A total of 30 children with FC were selected from the outpatient departm...
2022, 43(3): 128-134.
doi: 10.12259/j.issn.2095-610X.S20220316
Abstract:
Objective To compare the values of AIMS65, GBS, MGBS, EGBS, CRS, CANUKA, Child-Turcotte-Pugh （CTP）, MELD, and MELD-Na scoring systems in the evaluation of the prognosis of patients with liver cirrhosis and EGVB, and explore the factors affecting the ...
2022, 43(3): 135-141.
doi: 10.12259/j.issn.2095-610X.S20220304
Abstract:
The incidence of lung cancer in Xuanwei area of Yunnan Province ranks first in China, which is a typical air pollution related lung cancer. In recent years, Xuanwei lung cancer incidence rate continues to grow rapidly, showing a clear phenomenon of f...
The incidence of lung cancer in Xuanwei area of Yunnan Province ranks first in China, which is a typical air pollution related lung cancer. In recent years, Xuanwei lung cancer incidence rate continues to grow rapidly, showing a clear phenomenon of f...
2022, 43(3): 142-147.
doi: 10.12259/j.issn.2095-610X.S20220324
Abstract:
With the development of medical diagnostic technology, the detection rate of adrenal tumor is increasing year by year. As a new technology, radiomics can mine, predict and analyze the deep-seated data which is difficult for human eyes to recognize. I...
With the development of medical diagnostic technology, the detection rate of adrenal tumor is increasing year by year. As a new technology, radiomics can mine, predict and analyze the deep-seated data which is difficult for human eyes to recognize. I...
2022, 43(3): 148-153.
doi: 10.12259/j.issn.2095-610X.S20220314
Abstract:
Objective To evaluate the effect of PBL teaching method on the critical thinking ability of surgical interns majoring in clinical medicine, so as to improve the critical thinking ability of undergraduates majoring in clinical medicine. Methods A to...
2022, 43(3): 154-159.
doi: 10.12259/j.issn.2095-610X.S20220328
Abstract:
Objective To explore outcome of online learning during the period of Covid-19 pandemic, and provide the theoretical basis for blended teaching methods of online and offline. Methods A total number of 917 undergraduates at a University in Kunming, w...
2022, 43(3): 160-165.
doi: 10.12259/j.issn.2095-610X.S20220302
Abstract:
Objective To investigate the mental status of the patients in rheumatic immunology department, and evaluate the risk of depression and suicide, so as to identify the patients with depression and high risk of suicide, ensure the safety of the patients...
2022, 43(3): 166-170.
doi: 10.12259/j.issn.2095-610X.S20220315
Abstract:
Objective To explore the effect of mechanical vibration of electric toothbrush on neonatal sputum excretion. Methods 120 children with neonatal infectious pneumonia were randomly divided into control group and experimental group. The control group r...
