2022 Vol. 43, No. 7

Original Articles Basic of Medicine
Changes of Intestinal Inflammatory Injury Induced by DSS in GC-C-/- Mice
Guili LIANG, Canmei LI, Chengfeng XING, Yunlong DONG, Juan WANG, Zi LEI, Yinglei MIAO, Danfeng LAN
2022, 43(7): 1-8. doi: 10.12259/j.issn.2095-610X.S20220712
Abstract(3194) HTML PDF(195)
Abstract:
Objective To investigate the role of guanylate cyclase C (GC-C) signaling pathway in the intestinal inflammatory injury of mice induced by sodium dextran sulfate (DSS). Methods The colitis models were constructed using DSS in the GC-C gene knockout (...
Expressions and Clinical Significance of LEA and CDw75 in Colorectal Adenocarcinoma
Hong SHEN, Hairong HUA, Liping GAO, Yixiao HE, Xuezhi YANG, Xiangfei ZENG, Fang WANG, Jingling SONG
2022, 43(7): 9-17. doi: 10.12259/j.issn.2095-610X.S20220717
Abstract(3444) HTML PDF(26)
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Objective To investigate the expression and clinical significance of LEA and CDw75 in human colorectal adenocarcinoma. Methods The expressions of LEA and CDw75 were detected by immunohistochemistry staining in 11 cases of normal colorectal normal mu...
Effects of miR-208a on Myocardial Ischemia-reperfusion Injury by Regulating the Expression of QKI5 in Rats
Wei YANG, Hongyan CHEN, Wendong CHEN, Yanqiong WANG, Xiangfeng BAI
2022, 43(7): 18-24. doi: 10.12259/j.issn.2095-610X.S20220724
Abstract(4331) HTML PDF(29)
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Objective To investigate the effect and mechanism of miR-208a on myocardial injury induced by myocardial ischemia reperfusion by regulating the expression of QKI5 in rats. Methods Thirty-two male SD rats were randomly divided into sham group, I/R gr...
CircRNA EZH2 Promotes Proliferation and Migration of Prostate Cancer Cells by Regulating miR-30c-5p
Bin ZHAO, Yuanpeng DUAN, Guoying ZHANG, Chengwei BI, Libo YANG, Zhiyu SHI, Yong YANG, Jianpeng ZHANG, Ting GAO
2022, 43(7): 25-32. doi: 10.12259/j.issn.2095-610X.S20220731
Abstract(3825) HTML PDF(37)
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Objective To investigate the effect and related mechanism of circRNA EZH2 on proliferation and migration of prostate cancer cells through miR-30c-5p. Methods The expression difference and survival probability of EZH2 in prostate cancer were analyzed...
YLR358C Regulates Cell Wall Integrity of Saccharomyces cerevisiae
Yu ZHANG, Mengyan LI, Hanying WANG, Yanfang GUO, Jiaqing MA, Weiqun WANG
2022, 43(7): 33-37. doi: 10.12259/j.issn.2095-610X.S20220730
Abstract(2720) HTML PDF(82)
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Objective To observe the effect of Saccharomyces cerevisiae (S. cerevisiae) YLR358C deletion on cell wall integrity. Methods The growth of YLR358CΔ yeast was observed by spot assay; the effect of YLR358C on yeast cell wall was analyzed by Calcofluor ...
Scutellarin Ameliorates Liver Fibrosis in Nonalcoholic Fatty Liver Disease by Inhibiting NOX Expression
Yongrui YANG, Liyuan WANG, Haiwen LI, Zhirong ZHAO, Rui PU, Guishuai WU, Shude LI
2022, 43(7): 38-45. doi: 10.12259/j.issn.2095-610X.S20220721
Abstract(3165) HTML PDF(35)
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Objective To investigate the effect of scutellarin (SCU) on the expression of NOX (NOX2, NOX4) and the degree of liver fibrosis induced by high fat and high sugar in non-alcoholic fatty liver disease (NAFLD). Methods Sixty rats were randomly divide...
HLA-G Enhances the Killing Effect of NK Cells on Cervical Cancer Cells by Promoting the Expression of Activated Receptor
Qian LIU, Tuerxun HATILA, Hasimu AXIANGU
2022, 43(7): 46-54. doi: 10.12259/j.issn.2095-610X.S20220714
Abstract(3272) HTML PDF(32)
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Objective To explore the effect of HLA-G expression on NK cell surface activation receptor in cervical cancer cells. Methods Real-time PCR (RT-PCR) and Western Blot (WB) methods were used to examine the expression of HLA-G in cervical cancer cells a...
Clinical Research
Significance of CXCL10 as a Biomarker of Liver Cirrhosis
Siqi LI, Wenlin TAI
2022, 43(7): 55-61. doi: 10.12259/j.issn.2095-610X.S20220711
Abstract(3184) HTML PDF(39)
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Objective To investigate the potential of CXCL10 as a noninvasive biomarker of liver cirrhosis and its mechanism in the progression of liver fibrosis. Methods Peripheral blood samples of EDTA-K2 anticoagulant tubes were collected from cirrhotic pati...
Effects of Different Frequency Intense Pulsed Light Treatment on Tear Film Stability and Meibomian Gland Function in Patients with Meibomian Gland Dysfunction
Liping LI, Hongchao ZHAO, Yanfang CHEN, Tao ZENG, Huiqiong ZHAO, Jun LI
2022, 43(7): 62-67. doi: 10.12259/j.issn.2095-610X.S20220708
Abstract(2864) HTML PDF(21)
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Objective To analyze the effects of different frequency intense pulsed light (IPL)treatment on tear film stability and meibomian gland function in patients with MEibomian gland dysfunction (MGD). Methods One hundred and forty eyes of 70 MGD patient...
A Randomized Single Blind Study on the Improvement of Social Disability and Self-efficacy in Depressive Disorder by Solution Focused Group Therapy
Wei WANG, Jing ZHANG, Yonghui ZHANG, Dengai DUAN, Xinju LIAO, Fang WANG, Jingling SONG
2022, 43(7): 68-73. doi: 10.12259/j.issn.2095-610X.S20220722
Abstract(2214) HTML PDF(32)
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Objective To focus on the difference between solution focused group therapy (SFGT) combined with Escitalopram and only use Escitalopram in the treatment of depression group, and evaluate the efficacy of focus resolution short-course group psychothera...
Analysis of the Influence of Maternal Systemic Factors on Endometrial Implantation Window in Women with Repeated Implantation Failure
Yun BAI, Lanping ZHONG, Tingting ZHANG, Yuerong WU, Lei LI
2022, 43(7): 74-79. doi: 10.12259/j.issn.2095-610X.S20220701
Abstract(2613) HTML PDF(91)
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Objective To analyze the maternal and systemic factors that affect the endometrial implantation window in women with repeated implantation failure in assisted reproductive therapy. Methods Retrospective analysis was made on the data of cases diagnos...
Clinical Analysis of Cervical Lymph Node Metastatic Squamous Cell Carcinoma of Unknown Primary Site
Shizhou LI, Xiaoguang HE, Yan LIN, Yuxiao LI, Xi YANG, Xiaoyu WANG, Shenghao YANG
2022, 43(7): 80-85. doi: 10.12259/j.issn.2095-610X.S20220710
Abstract(3663) HTML PDF(51)
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Objective To analyze the clinical characteristics of squamous cell carcinoma with cervical lymph node metastasis of unknown primary (CCUP) focus, explore the prognostic factors, and provide the basis for clinical diagnosis and treatment. Methods The...
Measurement and Analysis of Color of Maxillary Anterior Teeth in Kunming Area of Yunnan Province
Xiaocheng ZHU, Rui WANG, Min YANG, Wen FAN, Xiyun CHEN, Xianghong YANG
2022, 43(7): 86-91. doi: 10.12259/j.issn.2095-610X.S20220732
Abstract(3156) HTML PDF(13)
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Objective To analyze the change law of the color information of maxillary anterior teeth in Kunming, Yunnan Province, so as to provide a reference basis for clinical aesthetic prosthesis colorimetry. Methods Vita easyshade advanced 4.0 wireless comp...
Influence of Different Thyroid Surgery Methods on the Function of Parathyroid Glands
Hangcheng TIAN, Ruochuan CHENG, Yingsheng BAO, Yuhua ZHANG, Jun HAN, Hongmei KUANG, Changwei ZHOU
2022, 43(7): 92-96. doi: 10.12259/j.issn.2095-610X.S20220719
Abstract(2731) HTML PDF(21)
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Objective To explore the influence of different thyroid surgery methods on the function of parathyroid glands. Methods We analyzed the clinical data of 60 patients undergoing thyroid surgery, including 30 cases in the subtotal thyroidectomy group an...
Influence of Social Determinants of Health on Overall Survivals among People Died of Cancer
Zhongting YANG, Xingmei DU, Qingyun YE, Benyan LI, Mingfang QIN, Feng JIAO, Ying CHEN, Rui DENG, Yuan HUANG
2022, 43(7): 97-104. doi: 10.12259/j.issn.2095-610X.S20220727
Abstract(3155) HTML PDF(12)
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Objective To analyze the differences in overall survival (OS) among people died of cancer in Yunnan from the perspective of social determinants of health, and provide evidence to the strategic plan for cancer prevention and control. Methods Death re...
Real-world Data Analysis to Evaluate the Antiplatelet Efficacy of Clopidogrel Bisulfate After Stent Implantation with Volume Collection and Original Research
Xiaodong ZHANG, Long YANG, Wenhong SONG, Hongming LIU, Wei HU, Zhisong CHEN, Zhuo YU
2022, 43(7): 105-109. doi: 10.12259/j.issn.2095-610X.S20220728
Abstract(2697) HTML PDF(23)
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Objective To explore the anti-platelet efficacy of national bulk collection and original clopidogrel bisulfate after stent implantation in patients with acute coronary syndrome (ACS) in the real world. Methods We established a real-world database o...
Influence of Different Ventilation Strategies During Spontaneous Breathing Trials on Lung Aeration Among Patients Receiving Mechanical Ventilation
Meiju LI, Wenzhuo LI, Jinling LIU, Li YANG, Mingxian ZHU, Jing XIA
2022, 43(7): 110-115. doi: 10.12259/j.issn.2095-610X.S20220709
Abstract(2072) HTML PDF(18)
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Objective To evaluate the difference of Pressure Support vs T-Piece vs Automatic Tube Compensation Ventilation Strategies during Spontaneous Breathing Trials on lung aeration. Methods Sixty-nine cases of mechanically ventilated patients who were pre...
Efficacy and Clinical Application of Flunarizine Combined with Ginkgo damo in Treatment of Senile Vertigo
Rui CUN, Meiling CHEN
2022, 43(7): 116-120. doi: 10.12259/j.issn.2095-610X.S20220703
Abstract(3794) HTML PDF(23)
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Objective To investigate the therapeutic effect of flunarizine combined with ginkgo-damole in elderly patients with vertigo. Methods A total of 76 elderly patients with vertigo from July 2019 to July 2020 in Kunming Second People's Hospital were sel...
Comparison of Frailty Assessment Methods for Predicting Postoperative Complications in Hospitalized Elderly Patients
Yuxiao XIA, Xiuli FENG, Wei GUO, Shanjiao ZHONG, Yu DING, Manman DONG, Xuewei YANG, Ying ZHOU
2022, 43(7): 121-127. doi: 10.12259/j.issn.2095-610X.S20220723
Abstract(4014) HTML PDF(15)
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Objective To evaluate frailty of surgical elderly hospitalized patients by four kinds of frailty assessment tools, FP (frailty phenotype, FP), FI-CD (frailty index of accumulative deficits, FI-CD), Frail Scale, and TFI (tilburg frailty indicator, TFI...
Effect of Enhanced Recovery after Surgery Strategy on Stress Factors and Postoperative Rehabilitation of Patients with Ovarian cystectomy under Single-Port Surgery
Hongyun LIAO, Yali ZHOU, Hongyun GONG, Yiqun DUAN, Qiong LI, Siyu CHEN, Hong XU, Yixian YU
2022, 43(7): 128-133. doi: 10.12259/j.issn.2095-610X.S20220713
Abstract(2471) HTML PDF(19)
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Objective To explore the effect of enhanced recovery after surgery strategy on stress factors and postoperative rehabilitation of patients with ovarian cystectomy under single-port laparoscopy. Methods A total of 68 patients with ovarian cystectomy ...
Application of Syntaneous Trioscopy Combined with Bile Duct Suture Technique in Patients with Gallbladder Stones with Dilated Cholecholithiasis
Kejia LI, Ang LIU, Yanyang LI, Zhihong ZHANG, Guohui SHAO, Jiayun GE
2022, 43(7): 134-139. doi: 10.12259/j.issn.2095-610X.S20220707
Abstract(2294) HTML PDF(21)
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Objective To explore the value of triple mirror combination technique in patients with dilated choledocholithiasis. Methods A retrospective analysis of 81 patients with dilated common bile duct stones (common bile duct diameter 0.8cm) were admitted ...
AIDS Research
Clinical Characteristics of Talaromyces Marneffei Disease and Disseminated Nontuberculosis Mycobacterium Disease in AIDS Patients
Bo TIAN, Yinzhong SHEN, Jinsong BAI, Jun LIU, Haiyun CHEN, Jianjun SUN
2022, 43(7): 140-144. doi: 10.12259/j.issn.2095-610X.S20220718
Abstract(3998) HTML PDF(19)
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Objective To compare the clinical characteristics and analyzing the risk factors for poor prognosis of Talaromyces Marneffei and disseminated Nontuberculosis Mycobacterium disease in AIDS patients . Methods We retrospectively collected the data of c...
Reviews
Research Progress in Pathogenesis of Diabetic Encephalopathy
Cuiling WU, Hongyi LIU, Yuan FAN, Jiarui LIU
2022, 43(7): 145-151. doi: 10.12259/j.issn.2095-610X.S20220733
Abstract(3811) HTML PDF(99)
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Diabetic encephalopathy (DE) is one of the chronic complications associated with diabetes. It is affected by many risk factors. Its main clinical manifestations are cognitive impairment, decision making disorders and emotional disorders. At present, ...
Progress in Pathogenesis and Treatment of Enteric Hyperoxaluria
Shunhang YANG, Jiongming LI, Jianhe LIU, Guang WANG, Pei LI
2022, 43(7): 152-155. doi: 10.12259/j.issn.2095-610X.S20220734
Abstract(3740) HTML PDF(171)
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Enteric hyperoxaluria is a secondary hyperoxaluria characterized by excessive absorption of intestinal oxalate and increased urinary oxalate. Enteric hyperoxaluria is closely related to the occurrence of urinary calcium oxalate stones. It is of great...
Teaching Research
Multivariate Generalization Analysis for Students’ Evaluation on Teaching Level of Teachers in Medical Colleges
Nan CHENG, Haoyuan DENG, Jianzhong YIN, Meng WU, Yuan LUO, Qiong MENG
2022, 43(7): 156-161. doi: 10.12259/j.issn.2095-610X.S20220702
Abstract(2608) HTML PDF(78)
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Objective To evaluate the reliability of the Student Evaluation Scale for the Teaching Level of Teachers in Medical Universities (SESTLTMU) and determine the appropriate number of students in the teaching evaluation based on Multivariate Generalizabi...
Nursing Forum
Construction of Family Needs Scale of Critically Ill Patients with Tumor Based on Delphi Method
Xiaohua REN, Qiongyao GUAN, Pengyu CUI, Chunli LIAO
2022, 43(7): 162-167. doi: 10.12259/j.issn.2095-610X.S20220716
Abstract(4091) HTML PDF(24)
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Objective To construct the family needs scale of critically ill tumor patients by using Delphi method, and to provide a basis for accurately evaluating and m-e eting the needs of the family members of critically ill tumor patients. Methods Based on ...
Effect of Health Education in Programmed Nursing on Perioperative Anxiety and Compliance of Patients with Lung Cancer
Yanan KONG, Jinbao MAO, Zhenya ZOU, Lin LI, Xingchen SHANG, Xiangyun KONG
2022, 43(7): 168-171. doi: 10.12259/j.issn.2095-610X.S20220706
Abstract(3947) HTML PDF(77)
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Objective To explore the effect of health education implemented by nursing process on improving perioperative anxiety and treatment compliance of lung cancer patients. Methods Eighty-six lung cancer patients were randomly divided into experimental g...
Construction of the Recertification Evaluation Index System for the Orthopedic Specialist Nurses Based on the Delphi Method
Jun DA, Chao TANG, Xiaoyan LIU, Lin CHEN, Mingying YANG
2022, 43(7): 172-176. doi: 10.12259/j.issn.2095-610X.S20220704
Abstract(4232) HTML PDF(24)
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Objective To construct a recertification management system for orthopedic specialist nurses’ qualifications. Methods Through literature review and semi-structured interviews, a preliminarily orthopedic specialist nurse qualification recertification m...
Construction of Rehabilitation Log and Its Effect on Recovery after Laparoscopic Hepatocellular Carcinoma Resection
Ying ZHANG, Yan ZHOU, Jing GUO, Tao FENG, Fengxia YANG, Yao HUANG, Xiaofeng DENG, Lu ZHENG
2022, 43(7): 177-180. doi: 10.12259/j.issn.2095-610X.S20220729
Abstract(3985) HTML PDF(10)
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Objective Based on the concept of ERAS and the rehabilitation needs of patients after laparoscopic hepatocellular carcinoma resection, to construct a rehabilitation log after laparoscopic hepatocellular carcinoma resection and study its application e...