2023 Vol. 44, No. 1
2023, 44(1): 1-6.
doi: 10.12259/j.issn.2095-610X.S20230107
Abstract:
Objective To investigate the effect of down-regulation of Pin1 expression on lipid synthesis, proliferation and apoptosis of cervical cancer SiHa cells. Methods Western Blot was used to detect the expression of Pin1 in Hela, SiHa and H8 cells; Lenti...
2023, 44(1): 7-11.
doi: 10.12259/j.issn.2095-610X.S20230121
Abstract:
Objective To study the mutation types of OprD gene in Pseudomonas aeruginosa resistant to carbapenems but sensitive to cephalosporins (Car-R/Ceph-S). Methods Ten strains of Pseudomonas aeruginosa which were resistant to carbapenems but sensitive to c...
2023, 44(1): 12-18.
doi: 10.12259/j.issn.2095-610X.S20230104
Abstract:
Objective To explore the identification method of Papaver with the use of DNA barcoding technology and find reliable DNA barcoding sequence for intraspecific and interspecific identification of Papaver. Methods Five different species of Papaver rhoe...
2023, 44(1): 19-24.
doi: 10.12259/j.issn.2095-610X.S20230106
Abstract:
Objective To investigate the relationship between KRAS, NRAS and BRAF gene mutations and liver metastasis in colorectal cancer. Methods A total of 246 colorectal cancer tissue specimens were collected from the Affiliated Hospital of North Sichuan Me...
2023, 44(1): 25-30.
doi: 10.12259/j.issn.2095-610X.S20230124
Abstract:
Objective To establish a mouse model of necrotizing enterocolitis and detect the key protein molecules in serum of neonatal rats with early NEC, so as to preliminatively determine whether necrotizing enterocolitis is involved in early neonatal necrot...
2023, 44(1): 31-34.
doi: 10.12259/j.issn.2095-610X.S20230120
Abstract:
Objective To investigate the incidence probability and epidemiological characteristics of flat foot in school-age children (7~13 years old) in Kunming, and to provide the evidence for the prevention of flat foot. Methods The incidence of flat foot,...
2023, 44(1): 35-40.
doi: 10.12259/j.issn.2095-610X.S20230128
Abstract:
Objective To create a combined model and explore its value in predicting the rupture risk of acute type A aortic dissection (ATAAD). Methods The relevant data and the first cTn-I value of the ATAAD patients admitted and treated in a tertiary hospita...
2023, 44(1): 41-46.
doi: 10.12259/j.issn.2095-610X.S20230112
Abstract:
Objective To investigate the different expression levels of TNF-α, sTNFR-55 and sTNFR-75 in the induced sputum and serum of AECOPD patients and their clinical significance. Methods Forty AECOPD patients were enrolled and hospitalized during January ...
2023, 44(1): 47-53.
doi: 10.12259/j.issn.2095-610X.S20230111
Abstract:
Objective To investigate the relationship between dyslipidemia and its clinical features and renal pathological features in patients with IgA nephropathy. Methods 150 patients with lgA nephropathy were divided into dyslipidemia group and normal bloo...
2023, 44(1): 54-58.
doi: 10.12259/j.issn.2095-610X.S20230126
Abstract:
Objective To establish an early screening system for childhood acute lymphoblastic leukemia based on the detection of TEL-AML1 fusion gene in neonatal umbilical cord blood and to explore its clinical significance. Methods First, the newborn with hig...
2023, 44(1): 59-64.
doi: 10.12259/j.issn.2095-610X.S20230118
Abstract:
Objective Intraoperative use of a high-dose remifentanil may induce postoperative hyperalgesia. This paper aims to investigate whether low-dose nalmefene can prevent the postoperative hyperalgesia induced by high-dose remifentanil. Methods Ninety p...
2023, 44(1): 65-69.
doi: 10.12259/j.issn.2095-610X.S20230113
Abstract:
Objective To investigate the clinical significance of color Doppler ultrasound in the diagnosis and treatment of cesarean scar pregnancy. Methods A total of 82 CSP patients diagnosed and treated in the Department of Gynecology of Yunnan First Peopl...
2023, 44(1): 70-75.
doi: 10.12259/j.issn.2095-610X.S20230105
Abstract:
Objective To investigate the correlation of different degrees and sides of internal carotid artery stenosis with cognitive impairment. Methods From June 2017 to August 2018, patients for cerebrovascular examination with CTA or DSA were selected from...
2023, 44(1): 76-79.
doi: 10.12259/j.issn.2095-610X.S20230108
Abstract:
Objective To measure the size of the fifth metatarsal bone marrow cavity, the length of the intramedullary nail and the length of the fifth metatarsal bone in normal adults by X-ray, and to provide a basis for the selection of the diameter and length...
2023, 44(1): 80-84.
doi: 10.12259/j.issn.2095-610X.S20230122
Abstract:
Objective To investigate the clinical significance of c reactive protein and procalcitonin levels in neonatal ABO hemolytic jaundice . Methods A total of 50 ABO hemolytic jaundice neonates admitted to a grade III and class A hospital in Yunnan Provi...
2023, 44(1): 85-90.
doi: 10.12259/j.issn.2095-610X.S20230109
Abstract:
Objective To investigate the effect of intestinal segment resection and local tumor removal on the prognosis of patients with intestinal metastatic epithelial ovarian cancer. Methods The clinical data of the patients who were admitted to Yunnan Prov...
2023, 44(1): 91-96.
doi: 10.12259/j.issn.2095-610X.S20230110
Abstract:
Objective To examine the effect of dual-task (DT) training on mobility function in patients with Parkinson’s disease (PD). Methods 56 patients with PD were randomly divided into DT training group or single-task (ST) training group. Each group of pa...
2023, 44(1): 97-103.
doi: 10.12259/j.issn.2095-610X.S20230117
Abstract:
Objective To observe the clinical efficacy and safety of first-line nucleos (t)ide analogues antiviral therapy in newly diagnosed chronic hepatitis B patients with low viral load and uncertain stage. Methods A total of 96 diagnosed treatment-naive c...
2023, 44(1): 104-108.
doi: 10.12259/j.issn.2095-610X.S20230115
Abstract:
Objective To explore peripheral blood interleukin-6 ( IL-6), interleukin-10 ( IL-10) hypersensitive C-reactive protein ( hs-CRP) and procalcitonin ( PCT) in children with acute lymphoblastic leukemia ( ALL) co-infection. Methods A total of 141 child...
2023, 44(1): 109-115.
doi: 10.12259/j.issn.2095-610X.S20230116
Abstract:
Objective To investigate the characteristics and significance of nutritional status and immune function in patients with pulmonary tuberculosis. Methods 1041 tuberculosis patients admitted to Kunming Third People’s Hospital from March 2021 to March ...
2023, 44(1): 116-121.
doi: 10.12259/j.issn.2095-610X.S20230114
Abstract:
Objective To investigate the relationship among high-sensitive HBV-DNA load , high-sensitivity HBV-DNA load, HBV genotype distribution, HBV P region drug resistance mutation, HBeAg, HBsAg, ALT and its value of clinical application in patients among t...
2023, 44(1): 122-127.
doi: 10.12259/j.issn.2095-610X.S20230123
Abstract:
Objective To explore the relationship between the quantitative analysis of real-time ultrasound elastography and the prognosis of percutaneous transbiliary drainage (PTCD) in elderly patients with advanced malignant obstructive jaundice. Methods A r...
2023, 44(1): 128-134.
doi: 10.12259/j.issn.2095-610X.S20220818
Abstract:
Objective To investigate the value of enhanced CT radiomics model in predicting the short-term efficacy (within 6 months) of TACE combined with sorafenib in hepatocellular carcinoma. Method The clinical, pathological and preoperative CT images of 15...
2023, 44(1): 135-139.
doi: 10.12259/j.issn.2095-610X.S20230103
Abstract:
Metastatic prostate cancer (mPCa) will progress to castrate-resistant state after a period of androgen-deprivation therapy (ADT) alone. Therefore, increasing focus is being placed on the additional survival benefits that could potentially be achieved...
Metastatic prostate cancer (mPCa) will progress to castrate-resistant state after a period of androgen-deprivation therapy (ADT) alone. Therefore, increasing focus is being placed on the additional survival benefits that could potentially be achieved...
2023, 44(1): 140-143.
doi: 10.12259/j.issn.2095-610X.S20230101
Abstract:
Lung cancer is one of the most common tumors, and Yunnan has the highest incidence of lung cancer in China. Many patients are diagnosed with advanced lung cancer and are treated with a combination of chemotherapy, radiotherapy, targeted therapy, immu...
Lung cancer is one of the most common tumors, and Yunnan has the highest incidence of lung cancer in China. Many patients are diagnosed with advanced lung cancer and are treated with a combination of chemotherapy, radiotherapy, targeted therapy, immu...
2023, 44(1): 144-150.
doi: 10.12259/j.issn.2095-610X.S20230125
Abstract:
Pterygium is a common ocular surface disease in the population and its risk factors are mainly ultraviolet radiation. The pathogenesis mainly includes oxidative stress, phototoxicity, cell proliferation and apoptosis, extracellular matrix remodeling,...
Pterygium is a common ocular surface disease in the population and its risk factors are mainly ultraviolet radiation. The pathogenesis mainly includes oxidative stress, phototoxicity, cell proliferation and apoptosis, extracellular matrix remodeling,...
2023, 44(1): 151-155.
doi: 10.12259/j.issn.2095-610X.S20230127
Abstract:
Objective To explore the feasibility and effectiveness of the oral digital positioning system combined with the CBL teaching method in the teaching of orthodontic bracket bonding and positioning. Methods 56 students were divided into group A (28 stu...
2023, 44(1): 156-162.
doi: 10.12259/j.issn.2095-610X.S20230102
Abstract:
Objective To explore the key factors for improving the teaching quality of pediatric pharmacy with the use of Kano model. Method The students who practiced in the pharmacy department of Kunming Children’s Hospital from October 2021 to June 2022 were...
2023, 44(1): 163-167.
doi: 10.12259/j.issn.2095-610X.S20230129
Abstract:
Objective To analyze the effect of red light irradiation combined with lower extremity muscle strength training on lower extremity motor function, Toronto Clinical Scoring System (TCSS) score and superoxide dismutase (SOD) level in patients with diab...
2023, 44(1): 168-172.
doi: 10.12259/j.issn.2095-610X.S20230119
Abstract:
Objective To investigate the effect of fasting or feeding on intestinal oxygenation in neonates during the blood transfusion. Methods From June 2021 to July 2022, a total of 59 eligible neonates who received the red blood cell infusion treatment in ...