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RSS2023 Vol. 44, No. 11
2023, 44(11): 1-8.
doi: 10.12259/j.issn.2095-610X.S20231101
Abstract:
Objective To explore the mechanism of Dendrobium officinale against inflammatory aging based on network pharmacology and molecular docking and experimental verification. Methods We used related databases to obtain the action targets of the main comp...
2023, 44(11): 9-15.
doi: 10.12259/j.issn.2095-610X.S20231102
Abstract:
Objective To investigate Artemisinin-affected cell proliferation and aerobic glycolysis on clear cell renal carcinomas（ccRCC） through regulating ENO2 and clarify the mechanism. Methods ccRCC cell lines OSRC2 and ACHN were exposed to 0, 10, 20, 30, a...
2023, 44(11): 16-21.
doi: 10.12259/j.issn.2095-610X.S20231103
Abstract:
Objective To explore the role of miR-148a-3p in osteogenic differentiation and enamel development during in vitro tooth organogenesis and uncover its underlying molecular mechanism. Methods Human dental pulp stem cells and oral epithelial cells were...
2023, 44(11): 22-28.
doi: 10.12259/j.issn.2095-610X.S20231104
Abstract:
Objective To obtain the optimal extraction process of narciclasine from Hymenocallis littoralis by response surface center design. Methods Based on the single factor experiment, temperature, time and liquid-to-solid ratio were selected to establish ...
2023, 44(11): 29-37.
doi: 10.12259/j.issn.2095-610X.S20231105
Abstract:
Objective To investigate the intervention effect and mechanism of Saikosaponin A on noise-induced tinnitus in a mouse model. Methods Fifty mice were randomly divided into control group（Control group）, noise-induced tinnitus mouse model group（BBN gr...
2023, 44(11): 38-46.
doi: 10.12259/j.issn.2095-610X.S20231106
Abstract:
Objective To observe whether Huashi Runjing Decoction can inhibit the inflammatory response in rats with desmoplastic male dry eye disease, and to explore its potential mechanism of action. Methods 60 healthy male SD rats were randomly divided into 4...
2023, 44(11): 47-55.
doi: 10.12259/j.issn.2095-610X.S20231107
Abstract:
Objective Bioinformatics was used to analyze the correlation between CAV1 expression and its prognostic value and immune infiltration in various tumors and to clarify its value in evaluating tumor prognosis. Methods The mRNA expression level of CAV1...
2023, 44(11): 56-62.
doi: 10.12259/j.issn.2095-610X.S20231108
Abstract:
Objective To investigate the effect of ZNF384 on the proliferation and metastasis of HCC by regulating GCLM and demonstrate the specific mechanism. Methods si-ZNF384 and pcDNA-GCLM were transfected into HepG2 and HuH7 cell lines of HCC, respectively...
2023, 44(11): 63-69.
doi: 10.12259/j.issn.2095-610X.S20231109
Abstract:
Objectives To investigate the effects of sacubitril/valsartan （S/V） on cardiac function and ventricular arrhythmias in patients with chronic heart failure with reduced ejection fraction（HFrEF）who underwent primary prevention of sudden cardiac death （...
2023, 44(11): 70-75.
doi: 10.12259/j.issn.2095-610X.S20231110
Abstract:
Objective To explore the effect of intrauterine hyperglycemia on peripheral inflammatory reaction of cord blood of offspring with gestational diabetes mellitus（GDM）. Methods The objects of this study were the offspring of women who delivered in the ...
2023, 44(11): 76-81.
doi: 10.12259/j.issn.2095-610X.S20231111
Abstract:
Objective To analyze the effects of various dosages of vitamin D（VitD） supplementation on bone metabolism and growth and development indicators of preterm infants. Methods Preterm infants with gestational age < 34 weeks or birth weight < 1500 ...
2023, 44(11): 82-86.
doi: 10.12259/j.issn.2095-610X.S20231112
Abstract:
Objective To establish a method for sterility test of non-aqueous clonazepam injection, and explore the effect of organic solvent on sterility test. Methods With reference to the 2020 edition of Chinese Pharmacopoeia, the effects of organic solvents...
2023, 44(11): 87-93.
doi: 10.12259/j.issn.2095-610X.S20231113
Abstract:
Objective To investigate the variables that affect social anxiety in leukemia-affected kids. Methods In order to better understand the 92 leukemia patients at the hematology unit of Kunming Children's Hospital, basic demographic data and measures of...
2023, 44(11): 94-99.
doi: 10.12259/j.issn.2095-610X.S20231114
Abstract:
Objective To investigate the clinical efficacy of continuous renal replacement therapy（CRRT） in patients with severe burn sepsis. Methods Forty patients with sepsis caused by severe burns who met the inclusion criteria and were admitted to the Depa...
2023, 44(11): 100-107.
doi: 10.12259/j.issn.2095-610X.S20231115
Abstract:
Objective To systematically describe and evaluate self-help intervention in patients with type 2 diabetes mellitus, to provide guidance for future self-help intervention research through evidence mapping method. Methods Related studies on self-help ...
2023, 44(11): 108-112.
doi: 10.12259/j.issn.2095-610X.S20231116
Abstract:
Objective To explore and analyze the clinical application efficacy and prospect of neuronavigation positioning assisted endoscopic transnasal sphenoid approach for resection of pituitary adenomas under general anesthesia. Methods A total of 68 patie...
2023, 44(11): 113-119.
doi: 10.12259/j.issn.2095-610X.S20231117
Abstract:
Objective To analyze the differences in liver and kidney function, immune function, and drug resistance between nontuberculous mycobacteria-infected people and healthy people. Methods We collected 122 cases of Nontuberculous Mycobacterium infected ...
2023, 44(11): 120-125.
doi: 10.12259/j.issn.2095-610X.S20231118
Abstract:
Objective To explore the care burden and influencing factors of the primary caregivers of severe mental illness patients in Xundian County, Kunming City. Methods The primary caregivers of registered severe mental illness patients in Xundian County w...
2023, 44(11): 126-134.
doi: 10.12259/j.issn.2095-610X.S20231119
Abstract:
Objective To investigate the efficacy and safety of Sofosbuvir/Velpatasvir ± ribavirin（SOF/VEL±RBV） in the treatment of genotype 3 chronic hepatitis C cirrhotic patients. Methods Patients diagnosed with genotype 3（GT3） HCV infection and treated at t...
2023, 44(11): 135-139.
doi: 10.12259/j.issn.2095-610X.S20231120
Abstract:
Objective To analyze the correlation between PEAR1 gene polymorphism and ischemic stroke, so as to provide a scientific basis for further research on the pathogenesis of ischemic stroke, and provide new ideas for disease prevention and treatment Met...
2023, 44(11): 140-144.
doi: 10.12259/j.issn.2095-610X.S20231121
Abstract:
Objective To investigate the relationship between leptin（LEP） 、serum uric acid（SUA） and obese patients with type 2 diabetes mellitus（T2DM）. Methods According to body mass index（BMI）, 111 newly diagnosed T2DM patients were divided into normal weight g...
2023, 44(11): 145-151.
doi: 10.12259/j.issn.2095-610X.S20231122
Abstract:
Objective To investigate the application of point-of-care gastric antrum ultrasonography in the risk assessment of aspiration in children undergoing emergency surgery. Methods A total of 120 cases of pediatric emergency surgery in Jingzhou Central H...
2023, 44(11): 152-157.
doi: 10.12259/j.issn.2095-610X.S20231123
Abstract:
Objective To investigate the prevalence of HIV-1 drug resistance and genotypes in HIV/AIDS patients before antiretroviral therapy in Dali Bai Autonomous Prefecture（Dali） , so as to provide a theoretical basis for more effective antiviral drug applica...
2023, 44(11): 158-163.
doi: 10.12259/j.issn.2095-610X.S20231124
Abstract:
This paper reviews the diagnostic criteria, epidemiology, hazards, mechanisms, risk factors, risk assessment and targeted care of urinary tract infection （UTI） in patients with ureteral dermatostomy. The paper proposes the necessity of constructing a...
This paper reviews the diagnostic criteria, epidemiology, hazards, mechanisms, risk factors, risk assessment and targeted care of urinary tract infection （UTI） in patients with ureteral dermatostomy. The paper proposes the necessity of constructing a...
2023, 44(11): 164-169.
doi: 10.12259/j.issn.2095-610X.S20231125
Abstract:
Non-alcoholic fatty liver disease is emerging as one of the most prevalent chronic liver diseases in children worldwide, and bile acids, which play an important role in the enterohepatic circulation are becoming increasingly prominent in its pathogen...
Non-alcoholic fatty liver disease is emerging as one of the most prevalent chronic liver diseases in children worldwide, and bile acids, which play an important role in the enterohepatic circulation are becoming increasingly prominent in its pathogen...
2023, 44(11): 170-174.
doi: 10.12259/j.issn.2095-610X.S20231126
Abstract:
Objective To establish a systematic psychological intervention based on S-ABC framework, and to explore its effects on perioperative psychological distress and immune function in patients with primary liver cancer. Methods A medical management team ...
2023, 44(11): 175-182.
doi: 10.12259/j.issn.2095-610X.S20231127
Abstract:
Objective To explore the influence of wearable device-based pulmonary rehabilitation（PR） mode on the rehabilitation effect of patients with chronic obstructive pulmonary disease（COPD）. Methods The patients with COPD who were hospitalized in our hosp...
2023, 44(11): 183-187.
doi: 10.12259/j.issn.2095-610X.S20231128
Abstract:
Objective To verify the validity of difficult venous access score in pediatric peripheral venipuncture and explore its applicability in pediatric venous access indwelling strategy. Methods The convenience sampling method was used to select inpatient...
2023, 44(11): 188-194.
doi: 10.12259/j.issn.2095-610X.S20231129
Abstract:
Objective To investigate the supportive care needs of patients after radical surgery for breast cancer based on the Kano model and define their attributes. Methods Convenience sampling was used to select 210 patients who underwent radical surgery fo...
