2023 Vol. 44, No. 12

Original Articles Basic of Medicine
Chemical Compounds Isolated from Dendrobium crepidatum and Their Bioactive Activities
Chenxi ZHUANG, Huimin WANG, Yaping CHEN, Rui ZHANG, Jinrong ZHENG, Meihong LI, Yupeng LI
2023, 44(12): 1-5. doi: 10.12259/j.issn.2095-610X.S20231231
Abstract(1587) HTML PDF(16)
Abstract:
Objective To study the chemical constituents from the herbs of Dendrobium crepidatum and identify its antitumor bioactive compounds. Methods The constituents were extracted by methyl alcohol and isolated by CC and Sephadex LH-20. Their structures we...
Effect of Median Nerve Electrical Stimulation on Synaptic Plasticity in Ischemic Stroke Rats
Chengcai ZHANG, Rong NING, Na CHEN, Yichen PENG, Li ZHOU, xichen YANG, Jingyi LU, Pengyue ZHANG, Rui LI
2023, 44(12): 6-12. doi: 10.12259/j.issn.2095-610X.S20231201
Abstract(1369) HTML PDF(20)
Abstract:
Objective To investigate the effects and mechanisms of median nerve electrical stimulation on synaptic plasticity in ischemic stroke rats. Methods 18 healthy male SD rats were randomly divided into Sham group(n = 6), ischemic stroke group(MCAO group...
Effects of Different Fluids on Microcirculation and Inflammatory Factors in Rabbits with Hemorrhagic Shock
Wensong DING, Qicai QU, Hong LI, Liu YANG, Jianping TAO, Yongyu SI
2023, 44(12): 13-19. doi: 10.12259/j.issn.2095-610X.S20231202
Abstract(1125) HTML PDF(8)
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Objective To study the effects of different types of fluid resuscitation on mesenteric microcirculation and inflammatory factors in rabbits with hemorrhagic shock. Methods The model of hemorrhagic shock rabbits was established by reducing the basic ...
Role of Mertk-mediated NF-κb Pathway in Inflammatory Response of Schwann Cells
Yidan FU, Wenting CHEN, Xiaoyang SU, Yan ZHAO, Danfeng LAN, Qiuping YANG
2023, 44(12): 20-24. doi: 10.12259/j.issn.2095-610X.S20231203
Abstract(1138) HTML PDF(17)
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Objective To explore the regulatory effect of Mertk expression level on NF-κb pathway in rat Schwann cells and its possible mechanism. Methods Rat Schwann cells were cultured in vitro, and the expression of Mertk in Schwann cells exposed to high glu...
The Role of miRNA-15a/16 in Regulating Bmi-1 Protein in Ovarian Cancer Resistance to Cisplatin Chemotherapy
Yangyang LIAN, Hongping YUE, Ya DUAN, Hongwen HU, Fang LUO
2023, 44(12): 25-31. doi: 10.12259/j.issn.2095-610X.S20231204
Abstract(1058) HTML PDF(11)
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Objective To investigate the mechanisms of miRNA-15a and miRNA-16 in the process of reversing cisplatin resistance in ovarian cancer. Methods Human ovarian cancer cisplatin-resistant cell lines CoC1/DDP were transfected with miRNA-15a and miRNA-16 m...
miR-218-5p Inhibits the Development of Colon Cancer by Regulating LAYN
Bing CAI, Wei ZHANG, Jing LIU, Yi LIU
2023, 44(12): 32-40. doi: 10.12259/j.issn.2095-610X.S20231206
Abstract(1062) HTML PDF(17)
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Objective To investigate the expression level of miR-218-5p and LAYN in colon cancer and the effects of their regulatory relationship on the progress of colon cancer. Methods RT-qPCR was used to detect the expression of miR-218-5p in colon cancer ti...
Study on the Influence of Yunnan Rice Products on Blood Sugar
Murong JIANG, Yuanqin LEI, Ke ZHANG, Qiumei LIU, Wenli YANG, Hongyi LIU, Jie YAN, Qingwen ZHANG
2023, 44(12): 41-45. doi: 10.12259/j.issn.2095-610X.S20231207
Abstract(1395) HTML PDF(15)
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Objective To explore the effect of Yunnan specialty rice products on blood sugar by measuring the glycemic index of 5 Yunnan special rice foods: rice noodles, rice cakes, rice rolls, sour rice noodles and dry rice noodles. Methods Following the natio...
Clinical Research
Effect Analysis of Transurethral Resection of Prostate Combined with Endocrine Therapy for Advanced Prostate Cancer
Pingbo XIE, Mingsheng LIU, Hongqing ZHOU, Shaomei WU, Tao SHAO, Feng GUO
2023, 44(12): 46-50. doi: 10.12259/j.issn.2095-610X.S20231208
Abstract(1064) HTML PDF(24)
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Objective To evaluate the efficacy and safety of transurethral resection of Prostate(TURP) combined with endocrine therapy in patients with advanced prostate cancer. Methods A retrospective analysis was conducted on 87 cases of late-stage prostate c...
Study on Immune Function and Drug Resistance of Tuberculosis Patients Co-infected with HBV,HCV and HIV in Yunnan
Xiaoyan WANG, Ya LI, Chenglu HE, Lin WANG, Zhiqiang MA, Xinrui WAN
2023, 44(12): 51-58. doi: 10.12259/j.issn.2095-610X.S20231209
Abstract(1125) HTML PDF(20)
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Objective To explore the co-infection rate, immune function and drug resistance status among tuberculosis patients co-infected with HBV, HCV and HIV in Yunnan. Methods A total of 2271 TB patients in Yunnan province admitted to the Third People's Hos...
Rare Cases of Hepatitis B Virus Infection Combined with Severe Cholinesterase Deficiency not Caused by Liver Dysfunction: Two Case Reports and Literature Review
Baoli BAI, Xiaolin KUANG, Mingfen HU, Guoji CHANG, Lu ZHANG, Shenghao LI, Qingqing WANG
2023, 44(12): 59-64. doi: 10.12259/j.issn.2095-610X.S20231210
Abstract(1060) HTML PDF(22)
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Objective To analyze the hepatitis B virus infection with extreme reduction of cholinesterase(CHE) not caused by liver synthesis dysfunction, and to explore its clinical significance. Methods The clinical data of 2 rare cases hospitalized in the 3r...
Efficacy of Transaxillary Approach Endoscopic Thyroid Surgery for the Treatment of Single-Sided Thyroid Cancer
Wei WANG, Qingxia YANG, Juanzhang LUO, Yahong WANG, Fuke WANG, Ruimei SUN
2023, 44(12): 65-71. doi: 10.12259/j.issn.2095-610X.S20231211
Abstract(1467) HTML PDF(14)
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Objective To investigate the safety and efficacy of endoscopic thyroid surgery through axillary approach in the treatment of unilateral papillary thyroid carcinoma. Methods A total of 135 patients admitted to Yunnan Cancer Hospital from April 2022 t...
Diffusion Tensor Imaging in the White Matter Changes of Patients with Pituitary Macroadenoma
Haoyu WANG, Qian HE, Bo ZHAO, Shizhen HE, Chen LIU, Peng WANG
2023, 44(12): 72-78. doi: 10.12259/j.issn.2095-610X.S20231212
Abstract(1027) HTML PDF(11)
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Objective To investigate the microstructural changes in white matter of pituitary adenoma patients when the anterior visual pathway is compressed using diffusion tensor imaging(DTI) and discuss the clinical significance of these changes. Methods Cli...
Sleep Status in 300 Infants and Young Children Aged 0~ 35 Months
Yanqiong RAO, Zhen XU, Jingjing SUN, Ou ZHANG, Sixiang LIU, Yu LING
2023, 44(12): 79-86. doi: 10.12259/j.issn.2095-610X.S20231213
Abstract(1291) HTML PDF(10)
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Objective To analyze the sleep status of infants and young children aged 0~35 months, in order to understand the common sleep problems and possible influencing factors of infants and young children. Methods Healthy infants aged 0~35 months who under...
A Study on Prognostic Value of Cellular Immunological Indicators in Omicron Variant Infected Elderly Severe Patients
Jiefu TANG, Dexing YANG, Shengzhe LIU, Qiang WANG, Kai FU, Zhenfang WANG, Ying LUAN, Min LI, Rong LIU
2023, 44(12): 87-94. doi: 10.12259/j.issn.2095-610X.S20231214
Abstract(1392) HTML PDF(5)
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Objective To investigate the characteristics of clinical cellular immunity and its relationship with prognosis in elderly patients with severe infection caused by Omicron variant. Methods The clinical data of 53 patients with Omicron variant infect...
Clinical Features and Prognosis of Langerhans Cell Histiocytosis in Children: An Analysis of 31 Cases
Haijin LI, Zhengcheng DUAN, Yan ZHOU, Liufang WANG, Chunhui YANG, Xin TIAN
2023, 44(12): 95-99. doi: 10.12259/j.issn.2095-610X.S20231215
Abstract(1181) HTML PDF(15)
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Objective To analyze the clinical characteristics of pediatric Langerhans cell histiocytosis(LCH), and to analyse the expression characteristics and prognosis of BRAF-V600E mutation in LCH. Methods The clinical data of 31 children with LCH admitted ...
Application of Pre-implantation Genetic Testing in the Patients with Turner Syndrome
Zhibiao CHEN, Qiuxiang HUANG, Lihua MAO, Guoyong CHEN, Yun LIU, Zhihong WANG
2023, 44(12): 100-105. doi: 10.12259/j.issn.2095-610X.S20231216
Abstract(1099) HTML PDF(9)
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Objective To investigate the application value of pre-implantation genetic testing(PGT) in patients with Turner syndrome. Methods The clinical data, embryonic development, PGT results and pregnancy outcome of 18 patients with Turner syndrome who und...
Use of Paroxetine in Outpatients of a Tertiary Psychiatric Hospital in Jiangsu Province
Yang FANG, Na WANG, Ru HUA
2023, 44(12): 106-110. doi: 10.12259/j.issn.2095-610X.S20231217
Abstract(1117) HTML PDF(8)
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Objective To evaluate the clinical application of paroxetine in outpatients. Methods A retrospective analysis was used to collect the prescription information of all outpatients who used paroxetine in the hospital from January 1, 2020 to June 30, 20...
Diagnostic Efficacy of Blood Inicators in the Diagnosis and Treatment of Gram-positive Cocci and Gram-negative Bacilli Infection
Yanbi ZHANG, Lei FENG, Rui SHI, Beibei LUO, Lingtong TANG, Huiying CAO, Qianye BI
2023, 44(12): 111-120. doi: 10.12259/j.issn.2095-610X.S20231218
Abstract(1326) HTML PDF(13)
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Objective To explore the differences in the effectiveness of using different blood indicators individually, in combination, and for dynamic monitoring in the diagnosis, differential diagnosis, and prognosis of bacterial infections. Methods 1843 case...
Association between MPV,PDW,PCT and Cardiac Function in Patients with Pulmonary Hypertension
Yan QIU, Yinli WANG, Mengmeng YANG, Liangmin GUO, Longhui YUAN
2023, 44(12): 121-126. doi: 10.12259/j.issn.2095-610X.S20231219
Abstract(1175) HTML PDF(5)
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Objective To study the association between mean platelet volume(MPV), platelet distribution width(PDW) and procalcitonin(PCT) and cardiac function in patients with pulmonary hypertension(PH) and their diagnostic value on heart failure. Methods 103 p...
Clinical Study on the Occlusal Change of Skeletal Class Ⅰ Malocclusion Treated with Invisible Appliance and Fixed Appliance
Qiqi YANG, Mengting CHEN, Jiangtian HU, Ting ZHOU
2023, 44(12): 127-132. doi: 10.12259/j.issn.2095-610X.S20231220
Abstract(1627) HTML PDF(17)
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Objective To compare the clinical efficacy of invisible appliance and fixed appliance in the treatment of skeletal class I malocclusion. Methods A prospective cohort study with a minimum sample size of no less than 19 subjects in each group was used,...
Correlation of 4D-CTA Imaging and Rupture Risk of Anterior Communicating Aneurysms
Yiming XU, Hongli ZHU, Xinyan ZHOU, Jing LIANG
2023, 44(12): 133-138. doi: 10.12259/j.issn.2095-610X.S20231221
Abstract(1062) HTML PDF(8)
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Objective To explore the correlation between 4D-CTA imaging and the risk factors for the rupture of anterior communicating aneurysms. Methods A total of 100 patients with anterior communicating aneurysms in the Department of Radiology of Yan’ an Hos...
Clinical Characteristics of 131 Children with Hand,Foot,and Mouth Disease Infected with EV71 and Preventive Effect of EV71 Vaccination
Shunqi SONG, Hongchao JIANG, Yunchao MA, Xingxing FENG, Tingyi DU, Hongfang ZHANG
2023, 44(12): 139-143. doi: 10.12259/j.issn.2095-610X.S20231222
Abstract(1072) HTML PDF(10)
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Objective To analyze the clinical features of children with EV71 positive hand, foot, and mouth disease(HFMD) and EV71 vaccination, and to explore the relationship between the occurrence of severe disease and the preventive effect of EV71 vaccine. M...
Epidemiology of CRKP Infection Outbreak in a Neonatal Intensive Care Unit
Weijie LI, Liqin CHEN, Yaling LI, Yonghui HAN, Xiaojuan LI, Ruogu WANG
2023, 44(12): 144-149. doi: 10.12259/j.issn.2095-610X.S20231223
Abstract(1183) HTML PDF(11)
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Objective To analyze the epidemiological characteristics of an outbreak of carbapenem resistant Klebsiella pneumoniae(CRKP) hospital infection in the neonatal intensive care unit(NICU) , and to explore possible causes of the outbreak. Methods Case a...
A Randomized Controlled Study on the Treatment of Multidrugresistant Tuberculosis with a Regimen Containing Bedaquiline Fumarate Tablets
Xing LIU, Chunhong YU, Weixian LI, Bing OUYANG, Lingjun SHEN
2023, 44(12): 150-158. doi: 10.12259/j.issn.2095-610X.S20231224
Abstract(1244) HTML PDF(21)
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Objective To explore the clinical efficacy and safety of betaquiline fumarate tablets in the treatment of multi drug resistant pulmonary tuberculosis. Methods Patients with multidrug-resistant tuberculosis(MDR-TB) admitted to the Third People's Hosp...
Effects of Paroxetine and Sulpiride in the Treatment of Social Phobia in Young Women and Its Effects on Neurotransmitter and Sleep Structure
Changji WU, Liu YANG, Xinyu ZHANG
2023, 44(12): 159-164. doi: 10.12259/j.issn.2095-610X.S20231225
Abstract(1081) HTML PDF(5)
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Objective To explore the effects of paroxetine and sulpiride in the treatment of social phobia in young women and the effects on neurotransmitters and sleep structure. Methods 102 young female patients with social phobia in our hospital from Februar...
Correlation of Preoperative Anemia Types with Pathological Features and Prognosis in Patients with Colorectal Cancer
Houji GUO, Mei YANG, Zhongwei QIN, Zhanyi HUANG
2023, 44(12): 165-170. doi: 10.12259/j.issn.2095-610X.S20231226
Abstract(987) HTML PDF(9)
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Objective To analyze the correlation between different types of anemia(small cell anemia and normal cell anemia) before operation and pathological features and prognosis of colorectal cancer patients. Methods The clinical data of 130 patients with c...
Effect of Different Shaping Angles on Endotracheal Intubation under Visual Laryngoscope for Beginners
Qicai QU, Liu YANG, Hui YU, Ningli ZHANG, Ping HU, Jian YANG
2023, 44(12): 171-176. doi: 10.12259/j.issn.2095-610X.S20231227
Abstract(1018) HTML PDF(13)
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Objective To compare the effects of 4 different shaping angle tubes on the success rate of tracheal intubation and postoperative pharyngeal complications among anesthetic beginners. Methods 160 patients who underwent laparoscopic cholecystectomy und...
Reviews
Advances in Arthroscopic Suture Techniques for Meniscal Injuries
Qipeng WANG, Kaiyu HOU, Chuan HE, Qinggang ZHAO
2023, 44(12): 177-183. doi: 10.12259/j.issn.2095-610X.S20231228
Abstract(1425) HTML PDF(15)
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The meniscus in the knee joint plays an important role in bearing load, shock absorption, joint lubrication, and increasing the stability of the knee joint in various directions. Meniscal injury is a common ailment in knee joint injuries, which can c...
Research Progress of Indole in E. coli Biofilms on the Surface of Biomaterials
Danyan SU, Wentian TANG, Jinxu YANG, Hua LIU, Bangsheng LI, Yingding ZHAO, Yunchao HUANG
2023, 44(12): 184-190. doi: 10.12259/j.issn.2095-610X.S20231229
Abstract(1611) HTML PDF(35)
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Escherichia coli is a highly adaptable opportunistic pathogen bacterium that can form biofilms on the surface of implants and generates persistent cells, leading to life-threatening infections that are difficult to treat with antibiotics alone. There...
Teaching Research
Practice and Exploration of the Cultivation of Scientific Innovation Ability Based on RBL Teaching Method
Lin WEI, Kezhen WANG
2023, 44(12): 191-196. doi: 10.12259/j.issn.2095-610X.S20231230
Abstract(1333) HTML PDF(21)
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Objective To explore the impact of research based learning(RBL) teaching method on undergraduate research innovation ability. Methods A total of 212 undergraduate students were involved in this study. Among them, 104 undergraduate students participat...