2023 Vol. 44, No. 5

Original Articles Basic of Medicine
Chemical Compounds Isolated from Pleione Bulbocodioides and Their Bioactive Activities
Xiaorong ZHOU, Meijun YANG, Yuena YANG, Mingxin XU, Yaping CHEN, Huimin WANG, Meihong LI, Yupeng LI
2023, 44(5): 1-5. doi: 10.12259/j.issn.2095-610X.S20230528
Abstract(3941) HTML PDF(35)
Abstract:
Objective To study the chemical constituents from the herbs of Pleione bulbocodioides and find theirs antitumor bioactive compounds. Methods The constituents were extracted by ethyl acetate and isolated by CC and Sephadex LH-20. Their structures wer...
The Regulation of VEGF Signal Axis by DATS and the Improvement of Formation of Placental Angiogenesis in URSA Mice
Jiamei SONG, Yang LIU, Tao SHI, Fangjie JIANG, Jingsi CHEN, Wen FAN, Yu LIANG, Yushi MENG
2023, 44(5): 6-11. doi: 10.12259/j.issn.2095-610X.S20230506
Abstract(3840) HTML PDF(31)
Abstract:
Objective The aim of this study is to investigate the effect of Diallyl trisulfide (DATS) on placental angiogenesis in mice with unexplained recurrent spontaneous abortion (URSA) and to explore its mechanism based on the vascular endothelial growth f...
Effects of Osteoking Combined with Antibiotic Cocktail on Insulin Resistance and Gut Flora in db/db Mice
Shaoyou DENG, Yulan ZHAO, Peijin WANG, Rong LI, Jintao LI, Hong ZHENG
2023, 44(5): 12-18. doi: 10.12259/j.issn.2095-610X.S20230530
Abstract(3445) HTML PDF(14)
Abstract:
Objective To investigate the effects of Osteoking combined with antibiotic cocktail on insulin resistance and gut microbiota in db/db mice. Methods The wild mice were used as the control group, while db/db mice were randomly divided into the model ...
The Incidence of Premature Delivery and Its Influencing Factors: A Maternal and Infant Health Cohort Study
Puxian PENG, Liping WANG, Hong LI, Yuan ZHANG, Songyuan TANG, Xingmei DENG
2023, 44(5): 19-25. doi: 10.12259/j.issn.2095-610X.S20230505
Abstract(3697) HTML PDF(11)
Abstract:
Objective To understand and analyze the incidence of premature delivery and its influencing factors in Qujing city, Yunnan province, so as to provide the scientific basis for the early intervention. Methods Based on Qujing Maternal and Child Health...
Analysis of Epidemiological Characteristics of Neonatal Rotavirus Infection from 2020 to 2022
Shuangshuang WANG, Liqin CHEN, Yaling LI, Weijie LI, Jiayi YANG
2023, 44(5): 26-31. doi: 10.12259/j.issn.2095-610X.S20230509
Abstract(3890) HTML PDF(70)
Abstract:
Objective To study the epidemiological characteristics of neonatal rotavirus (RV) infection, and to provide the guidance for the treatment and prevention of clinical diseases and the formulation of prevention and treatment strategies for RV infection...
The Current Situation and Related Factors of Alcohol Dependence among Dulong Ethnic Residents in Yunnan Province
Wen YANG, Fang YAN, Anqi KANG, Jinrong WANG, Ziyan WU, Chuanzhi XU, Yongbing XIA
2023, 44(5): 32-37. doi: 10.12259/j.issn.2095-610X.S20230513
Abstract(4612) HTML PDF(17)
Abstract:
Objective To explore the alcohol dependence state among Dulong ethnic residents in Yunnan province and its influencing factors so as to delay the increase in the prevalence. Methods With the use of the cross-sectional research methods, a random clus...
Epidemiological Characteristics of Male Patients with the First-episode Alcohol-induced Psychiatric Disorders
Xu YOU, Jianping LIU, Baoshuang XUE, Huiyun YIN, Lifen ZHANG, Xiaoqin WU
2023, 44(5): 38-42. doi: 10.12259/j.issn.2095-610X.S20230525
Abstract(3196) HTML PDF(15)
Abstract:
Objective To investigate the epidemiological characteristics of male patients with the first-ever alcohol-induced psychiatric disorders. Methods A retrospective survey was conducted and the medical records of inpatients first diagnosed with alcohol...
Test Result Analysis of the Drinking Water in Shizhong District Zaozhuang City from 2019 to 2022
Xianghua LIU
2023, 44(5): 43-46. doi: 10.12259/j.issn.2095-610X.S20230521
Abstract(2815) HTML PDF(6)
Abstract:
Objective To analyse the drinking water testing results in Shizhong district, Zaozhuang City from 2019 to 2022. Method 859 standard samples of drinking water in Shizhong District of Zaozhuang City from 2019 to 2022 were selected as the subjects. Acc...
Clinical Research
Expression Characteristics of COX2 and CDX2 in Laryngeal Squamous Cell Carcinoma and Their Prognostic Values in Patients with Laryngeal Squamous Cell Carcinoma
Liping ZHUANG, Kaixin WANG, Fang WANG, Hong YE
2023, 44(5): 47-52. doi: 10.12259/j.issn.2095-610X.S20230529
Abstract(2670) HTML PDF(7)
Abstract:
Objective To investigate the expression characteristics of COX2 and CDX2 in the development of laryngeal squamous cell carcinoma and their relationship with the prognosis in patients with laryngeal squamous cell carcinoma. Methods The expression ch...
Development and Validation of Risk Predicting Model for Severe Diabetic Peripheral Neuropathy Based on Glucose Variability Parameters
Fan ZHANG, Weichang GUO, Hong TAN, Hejia YIN, Luping PENG, Yan ZHAO, Huifang LI
2023, 44(5): 53-59. doi: 10.12259/j.issn.2095-610X.S20230526
Abstract(3359) HTML PDF(16)
Abstract:
Objective To develop and validate a risk prediction model for severe DPN in patients with type 2 diabetes using glucose variability parameters, and to provide the evidence for the prevention and treatment of diabetic chronic complications. Methods T...
Clinical Observation of SGLT-2 Inhibitors in Delaying the Progression of Diabetic Nephropathy
Ling ZHAO, Hongling ZHONG, Xinru GAO, Mei LI, Tingting MAO, Rongyong LI, Tingyu KE
2023, 44(5): 60-65. doi: 10.12259/j.issn.2095-610X.S20230527
Abstract(3177) HTML PDF(13)
Abstract:
Objective To investigate the clinical efficacy of SGLT2 inhibitors in delaying the progression of diabetic nephropathy based on "real world" clinical data. Methods A retrospective analysis was performed on 98 patients with diabetes who were treated ...
Clinical Characteristics and Genetic Testing of A Pedigree with Early-onset Parkinson's Disease Caused by PRKN Gene Mutation
Shusheng LIAO, Hong CHEN, Mei LIU, Chengyu PAN, Aidi LUO, Li ZHANG
2023, 44(5): 66-71. doi: 10.12259/j.issn.2095-610X.S20230504
Abstract(3603) HTML PDF(31)
Abstract:
Objective To investigate the clinical characteristics and gene mutations of 2 patients in 2 families of autosomal recessive early-onset Parkinson’s disease (AREP). Methods Clinical data and gene mutation analysis were performed on 2 patients from 2 ...
Association of Single Nucleotide Polymorphisms of Calcium Sensitive Receptor Gene with Calcium Nephrolithiasis and Hypercalciuria in Chinese Dai Population
Ji LI, Kunbin KE, Baiyu ZHANG, Yidao LIU, Jing BAI, Tao DONG, Zhencheng WANG, Deqiang QIN, Mengyue WANG, Hao LI
2023, 44(5): 72-80. doi: 10.12259/j.issn.2095-610X.S20230520
Abstract(3399) HTML PDF(10)
Abstract:
Objective To study the association of CaSR gene polymorphism with calcium nephrolithiasis and hypercalciuria in Chinese Dai population. Methods The Dai patients with calcium containing renal calculi in Dehong Prefecture, Yunnan Province, China were ...
Observation on the Efficacy of Optimal Pulse Technology in the Treatment of Meibomian Gland Dysfunction Related Dry Eyes Based on in Vivo Confocal Microscopy Classification
Mingyu CAI, Qian CAO, Junjun LONG, Guojun GAO, Lan LI
2023, 44(5): 81-89. doi: 10.12259/j.issn.2095-610X.S20230501
Abstract(3008) HTML PDF(14)
Abstract:
Objective To classify the meibomian gland dysfunction (MGD) with the use of in vivo confocal microscopy (IVCM), and to compare optimal pulse technology (OPT) combined with meibomian gland expression (MGX) in the treatment of different types of MGD-re...
Clinical Application of MRI Three-dimensional Visualization Reconstruction in the Evaluation of Complex Anal Fistula
Xia ZHENG, Xiaobo HUANG, Jing CHENG, Xu YANG, Dan HAN
2023, 44(5): 90-94. doi: 10.12259/j.issn.2095-610X.S20230516
Abstract(3375) HTML PDF(13)
Abstract:
Objective To explore the clinical value of MRI three-dimensional visualization (3DV) reconstruction technology in the evaluation of complex anal fistula. Methods The preoperative MRI data of 46 patients with complicated anal fistula confirmed by op...
Clinical Correletions between Helper T Cells 17,Regulatory T Cells and Chronic Actinic Dermatitis
Chenglin YANG, Jie HU, Jing WANG, Minhua WANG, Ling HUANG
2023, 44(5): 95-101. doi: 10.12259/j.issn.2095-610X.S20230511
Abstract(3147) HTML PDF(8)
Abstract:
Objective To investigate the the possible roles of helper T cells 17 (Thl7 cells) and regulatory T cells (Treg cells) of chronic actinic dermatitis. Methods The percentages of Th17 cells and Treg cells in CD4+ T cells in peripheral blood of 25 CAD p...
Clinical Application of Esketamine Combined with Propofol in Painless Abortion
Ningli ZHANG, Chen ZHOU, Yongyu SI, Jie OUYANG, Lan LIN, Ying CHEN, Qin NIU, Hong LI
2023, 44(5): 102-106. doi: 10.12259/j.issn.2095-610X.S20230514
Abstract(3218) HTML PDF(15)
Abstract:
Objective To explore the advantages of esketamine combined with propofol in painless abortion. Methods 50 patients who underwent the painless abortion were selected and randomly divided into the control group and the observation group, with 25 in eac...
Comparative Analysis of the Anterior and Posterior Approaches of the Posterior Rectus Sheath in Single-port TEP Surgery
Chengmin SHI, Tong ZHANG, Zhizhong WU, Huayou LUO, Yujian ZENG
2023, 44(5): 107-110. doi: 10.12259/j.issn.2095-610X.S20230522
Abstract(2766) HTML PDF(9)
Abstract:
Objective To explore the advantages and disadvantages of different approaches of single-incision laparoscopic surgery for the totally extraperitoneal inguinal hernia repair (SILS-TEP). Methods The data of single-port laparoscopic total extraperitonea...
Analysis of Factors Affecting Knee Joint Function Recovery Time after Platelet-rich Plasma and Arthroscopy for III Degree Meniscus Injury
Jindian TAN, Huaming HU, Song YANG, Jianping LIN, Jufeng WU
2023, 44(5): 111-116. doi: 10.12259/j.issn.2095-610X.S20230507
Abstract(3122) HTML PDF(15)
Abstract:
Objective To investigate the factors affecting the knee joint function recovery time after the platelet-rich plasma and arthroscopy for III degree meniscus injury. Methods From October 1, 2020 to August 20, 2022, 97 patients diagnosed as III degree ...
Comparative Study of Multiple Models Based on Baseline T2WI Images for Predicting Pathological Complete Remission of Progressive Rectal Cancer after Neo-adjuvant Chemoradiotherapy
Jingyu YANG, Ning XU, Yutao ZHANG, Fengchang HUANG, Yuanming JIANG, Liang YIN
2023, 44(5): 117-124. doi: 10.12259/j.issn.2095-610X.S20230512
Abstract(3357) HTML PDF(6)
Abstract:
Objective To investigate the predictive effectiveness of different models and the efficacy of baseline T2WI combined with machine learning imaging and to predict the pathological complete remission after the neo-adjuvant chemoradiotherapy (nCRT) in p...
The Predictive Value of Temperament in Children with Attention Deficit Hyperactivity Disorder
Jihua CUI, Shujin LI, Yu SONG, Yanfei YANG, Yanhui SUN, Jingjing SUN, Yu LING
2023, 44(5): 125-131. doi: 10.12259/j.issn.2095-610X.S20230518
Abstract(3127) HTML PDF(7)
Abstract:
Objective To explore the temperament characteristics of children with attention deficit hyperactivity disorder (ADHD) and to understand its predictive value in children with ADHD. Methods 183 children with ADHD , 45 children with ADHD and treated re...
The Analysis between Uterocervical Angles and Cervical Length in Predicting Preterm Labor
Qianwen ZHENG, Xiaoyan MA, Jihong LIU, Shanshan GUO, zhuoma ZHISHI
2023, 44(5): 132-137. doi: 10.12259/j.issn.2095-610X.S20230515
Abstract(3359) HTML PDF(12)
Abstract:
Objective To study the value of the cervical length (CL) and uterocervical angles (involving anterior uterocervical angles and posterior uterocervical angles) in predicting preterm labor to find new predicting markers via transvaginal ultrasound (TVU...
Clinical Value of Fecal SDC2 Gene Methylation Detection in Early Screening of Colorectal Cancer
Yuan WANG, Rong LI, Jiaojiao CHEN, Yanli SHEN, Fengdi HU
2023, 44(5): 138-143. doi: 10.12259/j.issn.2095-610X.S20230524
Abstract(3457) HTML PDF(80)
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Objective This study aims to investigate the clinical application of fecal recombinant human adhesin syndecan 2 (SDC2) gene methylation test in the early screening of colorectal tumors. Methods Eighty-seven subjects admitted to the hospital from Ma...
Application of Asphyxiation Technique in Thoracoscopic Segmentectomy
Xuan CHAI, Zhonghui WANG, Yahong WANG, Guangshun LIU, Zhenchao LV, Shihao SHAO
2023, 44(5): 144-153. doi: 10.12259/j.issn.2095-610X.S20230502
Abstract(2816) HTML PDF(7)
Abstract:
Objective To observe the effects of asphyxia oxygenation on intersegment plane display rate, intraoperative oxygen metabolism indexes, serum hypoxia inducible factor 1α (HIF-1α) and postoperative complications. Methods 75 patients aged 22 to 65 yea...
The Clinical Data Analysis of 2 499 Patients with Nasopharyngeal Carcinoma in Yunnan
Xiaoli WANG, Hongwei YANG, Ting DING, Ruiping WU, Kuixuan ZHU
2023, 44(5): 154-161. doi: 10.12259/j.issn.2095-610X.S20230523
Abstract(3030) HTML PDF(14)
Abstract:
Objective To analyze the clinical characteristics of nasopharyngeal carcinoma patients in Yunnan on the basis of the clinical data of hospitalized patients, and provide a basis for preventive measures. Methods The clinical data of 2 499 patients wi...
AIDS Research
Use and Replacement of Treatment Regimens for AIDS Patients on Antiretroviral Therapy
Bo TIAN, Chongxi LI, Yongmei JIN, Wei GUAN, Haiyun CHEN, Jun LIU
2023, 44(5): 162-167. doi: 10.12259/j.issn.2095-610X.S20230508
Abstract(3512) HTML PDF(18)
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Objective To understand the use of primary and menstrual ART regimens for HIV patients receiving antiviral treatment in different periods, and to analyze the dressing change situation and reasons of different drug combinations. Methods Patients init...
Reviews
Research Progress of Autophagy in the Development and Treatment of Bladder Cancer
Shi CHEN, Shi FU, Zhiyong TAN, Jiansong WANG, Haifeng WANG
2023, 44(5): 168-174. doi: 10.12259/j.issn.2095-610X.S20230503
Abstract(4077) HTML PDF(28)
Abstract:
Autophagy is a self-digestive process of cells degrading intracellular substances through lysosomes and is considered to be an important protection mechanism for tumors to maintain survival under stress conditions. A large number of evidence shows th...
Current Status and Research Progress of Immunotherapy for Melanoma
Cuihua FANG, Maohua PAN, Longcan ZHOU, Yucheng QIN, Yaming HUANG, Jia MA, Xi CHEN, Zhaoqing YANG
2023, 44(5): 175-179. doi: 10.12259/j.issn.2095-610X.S20230519
Abstract(3441) HTML PDF(133)
Abstract:
Melanoma is a highly lethal skin malignant tumor. Although years of clinical studies have proved that there are various methods for its treatment, such as surgery, chemotherapy, radiotherap, targeted therapy, etc., due to its low sensitivity, strong ...
Nursing Forum
Studies on the Development Status of Oral Specialty Nursing in Yunnan Province
Siyue LU, Juan LIU, Zhangcheng YIN, Wenlin LU, Qi SUN, Congchong SHI, Baofan LI, Xinchun ZOU, Lan YAO
2023, 44(5): 180-184. doi: 10.12259/j.issn.2095-610X.S20230517
Abstract(4129) HTML PDF(17)
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Objective To understand the current situation of oral specialty nurses in Yunnan Province at the end of the 13th five year plan period, and to provide a reference basis for formulating the plan of dental specialty in Yunnan Province and building a or...
Effect of Nutrition Clinical Nursing Pathway for Nasopharyngeal Carcinoma Patients Concurrent Radiotherapy and Chemotherapy
Jiang WU, Shuifen DAI, Qin LIU, Shoutao YANG, Jiang ZHANG, Jiao YANG, Qiongyao GUAN
2023, 44(5): 185-190. doi: 10.12259/j.issn.2095-610X.S20230510
Abstract(4788) HTML PDF(18)
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Objective To explore the effect of nutrition clinical nursing pathway for nasopharyngeal carcinoma patients (NPC) undergoing concurrent radiotherapy and chemotherapy. Methods A total of 162 patients with NPC who received the concurrent radiotherapy ...