2024 Vol. 45, No. 1
2024, 45(1): 1-7.
doi: 10.12259/j.issn.2095-610X.S20240101
Abstract:
Nonalcoholic fatty liver disease(NAFLD) is the most common chronic liver disease, with a global prevalence of approximately 30.05% to 32.4%. It is closely associated with various other diseases. In recent years, microRNAs(miRNAs) have played a crucia...
Nonalcoholic fatty liver disease(NAFLD) is the most common chronic liver disease, with a global prevalence of approximately 30.05% to 32.4%. It is closely associated with various other diseases. In recent years, microRNAs(miRNAs) have played a crucia...
2024, 45(1): 8-14.
doi: 10.12259/j.issn.2095-610X.S20240102
Abstract:
Objective To investigate the correlation between HLA-DM gene polymorphism and antibody response induced by poliomyelitis vaccine. Methods 355 healthy infants aged 2 to 3 months in Guangxi Zhuang Autonomous Region were selected as the study objects,...
2024, 45(1): 15-21.
doi: 10.12259/j.issn.2095-610X.S20240103
Abstract:
Objective To investigate the effect of transmembrane protein CD147 expression on AIM2 inflammasome-mediated pyroptosis and proliferation of cervical cancer cells. Methods Western Blot was used to detect the expression of CD147 in cervical cancer cell...
Metabolomics of Siha Supernatant in Cervical Cancer Cells with Down-regulated HPV16 E6/E7 Expression
2024, 45(1): 22-27.
doi: 10.12259/j.issn.2095-610X.S20240104
Abstract:
Objective To detecte the differential metabolites and related pathways in Siha cells of cervical cancer by screening the inhibition of HPV16 E6/E7 expression based on 1H NMR metabolomics so as to identify the key metabolic markers involved in the dev...
2024, 45(1): 28-34.
doi: 10.12259/j.issn.2095-610X.S20240105
Abstract:
Objective To investigate the effects of different culture conditions(RPMI-1640, DMEM and DMEM/F12 medium) on the passage of MPM cells isolated from the tissues of Malignant pleural mesothelioma(MPM), and to study the effects of CDKN2B on the prolifer...
2024, 45(1): 35-40.
doi: 10.12259/j.issn.2095-610X.S20240112
Abstract:
Objective Endothelial injury plays a crucial role in forming deep vein thrombosis. This study aims to compare the effectiveness of various methods for creating rabbit femoral vein thrombotic models after the endothelial injuryso as to provide a solid...
2024, 45(1): 41-47.
doi: 10.12259/j.issn.2095-610X.S20240107
Abstract:
Objective The aim of this study is to analyze the prevalence of depression and anxiety symptoms and its relationship with the socio-economic position(SEP) among the elderly people in Dai rural areas of Jinggu County, Yunnan province. Methods A mult...
2024, 45(1): 48-54.
doi: 10.12259/j.issn.2095-610X.S20240108
Abstract:
Objective To investigate the vaccination status and vaccination willingness of novel coronavirus in HIV/AIDS population in Yunnan.Methods From October 2021 to June 2022, a questionnaire survey was conducted among 2180 HIV/AIDS patients in Kunming, Q...
Objective To investigate the vaccination status and vaccination willingness of novel coronavirus in HIV/AIDS population in Yunnan.
2024, 45(1): 55-60.
doi: 10.12259/j.issn.2095-610X.S20240109
Abstract:
Objective To understand the intention of the community diabetes management application and analyze the related factors. Methods Diabetes patients in the community were selected as the research objects, and the diabetes management application intenti...
2024, 45(1): 61-66.
doi: 10.12259/j.issn.2095-610X.S20240110
Abstract:
Objective To analyze the relationship between the common clinical indicators and diabetic foot ulcer(DFU) in type 2 diabetes mellitus(T2DM) patients by using the cross-sectional study and to provide the reference indicators for clinical DFU monitorin...
2024, 45(1): 67-72.
doi: 10.12259/j.issn.2095-610X.S20240111
Abstract:
Objective To investigate the clinical characteristics and risk factors of thyroid dysfunction(TD) in malignant tumor patients treated with immune checkpoint inhibitors(ICIs). Methods A total of 157 cancer patients who were hospitalized and received ...
2024, 45(1): 73-77.
doi: 10.12259/j.issn.2095-610X.S20240106
Abstract:
Objective To investigate the changes of sex hormone levels in polycystic ovary syndrome(PCOS) in infertile population after the assisted reproductive technology treatment, and to provide an evidence for the choice of the treatment. Methods The medi...
2024, 45(1): 78-82.
doi: 10.12259/j.issn.2095-610X.S20240113
Abstract:
Objective To investigate the risk factors of relapse in patients with ischemic stroke using aspirin for single drug antiplatelet therapy.Methods A retrospective analysis was conducted on 200 patients with mild and medium ischemic stroke after 12 mon...
Objective To investigate the risk factors of relapse in patients with ischemic stroke using aspirin for single drug antiplatelet therapy.
2024, 45(1): 83-86.
doi: 10.12259/j.issn.2095-610X.S20240114
Abstract:
Objective T o investigate the distributions of vitamin K1 and K2 in infants of different age groups by comparing the serum levels of vitamin K1 and K2 in them. Methods 1177 infants from 0 to 3 months were divided into 6 age groups. Those born/treate...
2024, 45(1): 87-92.
doi: 10.12259/j.issn.2095-610X.S20240115
Abstract:
Objective To analyze the treatment strategy of the atrial septal defect in the surgical treatment of Ebstein’ s anomaly combined with the atrial septal defect and the short-term follow-up results of the treatment of Ebstein’ s anomaly. Methods A ret...
2024, 45(1): 93-99.
doi: 10.12259/j.issn.2095-610X.S20240116
Abstract:
Objective To explore the changes and clinical significance of D-dimer(D-D), prothrombin fragment 1+2(F1+2) and P-selectin in patients with acute deep venous thrombosis of lower extremities(DVT) before and after catheterization and thrombolysis. Meth...
2024, 45(1): 100-106.
doi: 10.12259/j.issn.2095-610X.S20240117
Abstract:
Objective To investigate the clinical and pathological characteristics of the extrapleural solitary fibrous tumor and the relevant differential diagnosis. Methods HE and immunohistochemical staining were performed on 26 samples of isolated fibrous t...
2024, 45(1): 107-115.
doi: 10.12259/j.issn.2095-610X.S20240118
Abstract:
Objective To explore the effects of bronchoalveolar lavage combined with microbiological rapid on-site evaluation in potential donor lung maintenance. Methods Brain death patients who met the inclusion criteria and were admitted to the Intensive Car...
2024, 45(1): 116-121.
doi: 10.12259/j.issn.2095-610X.S20240119
Abstract:
Objective To study the correlation between the changes of matrix metalloproteinase-9(MMP-9) and neutrophil/lymphocyte ratio(NLR) before and after the revascularization of acute ischemic stroke(AIS), so as to find biomarkers to predict the bleeding tr...
2024, 45(1): 122-126.
doi: 10.12259/j.issn.2095-610X.S20240120
Abstract:
Objective To investigate the impact of not using drainage on clinical outcomes after arthroscopic autologous semitendinosus tendon reconstruction with anterior cruciate ligament reconstruction. Methods From March 2022 to June 2023, 59 patients under...
2024, 45(1): 127-132.
doi: 10.12259/j.issn.2095-610X.S20240121
Abstract:
Objective To explore the correlation between the urinary neutrophil gelatinase-associated lipid carrier protein(NGAL) and Brachial artery flow-mediated vasodilation(FMD) in Prehypertension. Methods 156 patients with Prehypertension found to have th...
2024, 45(1): 133-135.
doi: 10.12259/j.issn.2095-610X.S20240122
Abstract:
Objective To analyze the changes of vitamin D in children with Henoch-Schonlein purpura(HSP). Methods 130 children with HSP from Kunming Children’ s Hospital between July 2022-July 2023 were selected as the study subjects and 100 healthy children wer...
2024, 45(1): 136-142.
doi: 10.12259/j.issn.2095-610X.S20240123
Abstract:
Objective To evaluate the effect of photo-activated disinfection(PAD) as a kind of adjuvant treatment on moderate to severe chronic periodontitis. Methods 21 patients with the chronic periodontitis(totally 218 selected sites) were randomly enrolled ...
2024, 45(1): 143-148.
doi: 10.12259/j.issn.2095-610X.S20240124
Abstract:
Objective To investigate the effects of the laparoscopic surgery and open surgery on the postoperative intestinal function recovery time in elderly patients with colorectal cancer(CRC). Methods 66 elderly patients with CRC and treated in the 2nd Peo...
2024, 45(1): 149-155.
doi: 10.12259/j.issn.2095-610X.S20240125
Abstract:
Objective To analyze the clinical characteristics and the antimicrobial resistance of respiratory tract infection in children in Baoshan City, guide clinicians to rationally apply antibiotics, and improve the success rate of treatment. Methods Retros...
2024, 45(1): 156-162.
doi: 10.12259/j.issn.2095-610X.S20240126
Abstract:
Objective To summarize the experience of multi-disciplinary team(MDT) in the pediatric department of Qujing Maternal and Child Health Hospital, and to evaluate the effectiveness of MDT on neonatal brain injury. Methods The clinical data of children ...
2024, 45(1): 163-167.
doi: 10.12259/j.issn.2095-610X.S20240127
Abstract:
Objective To investigate the effect of smoking on the semen quality in infertile men. Methods A total of 360 male infertility patients were enrolled and divided into the smoking group(\begin{document}$n $\end{document} =190) and non-smoking group(\be...
2024, 45(1): 168-171.
doi: 10.12259/j.issn.2095-610X.S20240128
Abstract:
The preparation edge of the tooth in oral restoration has always been the hot concern for dentists, and the improper preparation edge may lead to such diseases as caries and periodontitis, and ultimately lead to the restoration failure. The applicati...
The preparation edge of the tooth in oral restoration has always been the hot concern for dentists, and the improper preparation edge may lead to such diseases as caries and periodontitis, and ultimately lead to the restoration failure. The applicati...
2024, 45(1): 172-178.
doi: 10.12259/j.issn.2095-610X.S20240129
Abstract:
Herpes simplex viruses type 1(HSV1) is among the most ubiquitous human pathogens that cause a wide variety of disease states. The latent infection of the central nervous system and sporadically reactivation is the central part of HSV1 pathogenesis, w...
Herpes simplex viruses type 1(HSV1) is among the most ubiquitous human pathogens that cause a wide variety of disease states. The latent infection of the central nervous system and sporadically reactivation is the central part of HSV1 pathogenesis, w...
2024, 45(1): 179-186.
doi: 10.12259/j.issn.2095-610X.S20240130
Abstract:
Objective To explore the different latent class and characteristics of the cognitive ability level of undergraduate nursing students in hospice care based on the individual-centered perspective, and analyze its influencing factors to provide the refe...
2024, 45(1): 187-192.
doi: 10.12259/j.issn.2095-610X.S20240131
Abstract:
Objective To explore the impact of the three-level assistance model based on the narrative nursing theory on the mental health status of medical staff. Methods 140 medical staff working in a third class hospital in Xiangyang City were selected as th...