2024 Vol. 45, No. 10

Expert Forum
Mechanisms of Long Non-Coding RNAs in Cartilage Development and Related Diseases
Feifei XIE, Yinzi XIN, Min XU, Jinghan LI, Wei WANG
2024, 45(10): 1-7. doi: 10.12259/j.issn.2095-610X.S20241001
Abstract(547) HTML PDF(29)
Abstract:
The growth and disease progression of cartilage are highly complex, influenced by various growth factors, cytokines, and both internal and external environmental factors. This process is regulated by multiple intersecting biological signaling pathway...
Original Articles Basic of Medicine
Dendrobium Nobile Polysaccharide Improves Myocardial Injury in Diabetic Rats by Regulating Plin5 Mediated Fatty Acid β Oxidation of Cardiomyocytes
Jizhou LI, Hongwei LI, Shengyu TANG, Zejun JIANG, Mengmeng GUO, Yatian LI, Hongling YANG
2024, 45(10): 8-16. doi: 10.12259/j.issn.2095-610X.S20241002
Abstract(352) HTML PDF(29)
Abstract:
Objective To explore the mechanism of Dendrobium nobium polysaccharide on myocardial injury in diabetic rats by regulating the fatty acid β oxidation signaling pathway of cardiomyocytes from Plin5. Methods A total of 72 male SD rats of a clean grade...
Establishment of a Smooth Muscle Cell Model for Venous Grafts after Coronary Bypass Surgery
Hu ZHANG, Ling LIN, Ailing YANG, Rong SU, Bo HUANG
2024, 45(10): 17-21. doi: 10.12259/j.issn.2095-610X.S20241003
Abstract(287) HTML PDF(11)
Abstract:
Objective To explore the establishment of in vitro model of coronary artery bypass venous bridge in coronary artery bypass graft (CABG). Methods Rat venous smooth muscle cells were cultured in vitro and divided into 4 groups. The cells were stretche...
FGF2 Regulates Hypoxia-Induced Proliferation and Collagen Metabolism of Scleral Fibroblasts Through the PERK/EIF2α/ATF4 Signaling Pathway
Yuru ZHAI, Yan BAI, Yunyun LI
2024, 45(10): 22-28. doi: 10.12259/j.issn.2095-610X.S20241004
Abstract(731) HTML PDF(28)
Abstract:
Objectives To investigate the effects of FGF2 on the proliferation and collagen production of hypoxia-induced scleral fibroblasts (SF) and explore the downstream signaling pathways it regulates. Methods 5% O2 was used to stimulate the SF to induce m...
Effect of Compound Probiotic Powder on Immune Function of Mice
Shuaiqiang WANG, Kejin TONG, Shuofeng ZHANG
2024, 45(10): 29-35. doi: 10.12259/j.issn.2095-610X.S20241005
Abstract(710) HTML PDF(21)
Abstract:
Objective To explore the effect of compound probiotic powder on enhancing related immune function of organism, so as to provide theoretical basis and experimental support for further exploration and application of compound probiotic powder in the fut...
Clinical Research
Retrospective Cohort Study of Infliximab and Vederizumab in the Treatment of Moderate-to-severe Ulcerative Colitis
Hanyu ZHANG, Juan LUO, Mingzhi DONG, Qiyin CHEN, Fengrui ZHANG, Rui GUO, Junying TONG, Yinglei MIAO
2024, 45(10): 36-44. doi: 10.12259/j.issn.2095-610X.S20241006
Abstract(538) HTML PDF(25)
Abstract:
Objective To compare the efficacy and safety of Infliximab (IFX) and Vedolizumab (VDZ) in the treatment of moderate-to-severe ulcerative colitis (UC). Methods A total of 110 patients diagnosed with moderate-to-severe ulcerative colitis and treated w...
Association between Systemic Immune-Inflammation Index and Disease Activity in Patients with Systemic Lupus Erythematosus
Feng SHEN, Yifan YANG, Ru BAI, Shu LI, Shuang LIU, Jian XU
2024, 45(10): 45-49. doi: 10.12259/j.issn.2095-610X.S20241007
Abstract(684) HTML PDF(18)
Abstract:
Objective To explore a new method for assessing disease activity in patients with systemic lupus erythematosus (SLE) by evaluating the relationship between the level of the systemic immune-inflammatory index (SII) and disease activity in SLE patients...
Efficacy of Microvascular Decompression for Moderate to Severe Hemifacial Spasm and the Influencing Factors of Delayed Resolution
Kun WANG, Jun PU, Dongbo LI, Tao YANG
2024, 45(10): 50-54. doi: 10.12259/j.issn.2095-610X.S20241008
Abstract(430) HTML PDF(12)
Abstract:
Objective To investigate the clinical efficacy of microvascular decompression for moderate-to-severe hemifacial spasm and the influencing factors of delayed resolution. Methods Sixty patients with moderate-to-severe hemifacial spasm who underwent mi...
Application of Logistic Regression and Artificial Neural Networks in the Differential Diagnosis of LC-MPE
Ruicheng LI, Hongwei QIAN, Yanni FAN, Peipei ZHAO, Shan WEI, Huarong JING
2024, 45(10): 55-60. doi: 10.12259/j.issn.2095-610X.S20241009
Abstract(538) HTML PDF(17)
Abstract:
Objectives To evaluate the application value of carcinoembryonic antigen (CEA), ferritin (FRT), neuron-specific enolase (NSE), squamous cell carcinoma-related antigen (SCC), carbohydrate antigen 50 (CA50), carbohydrate antigen 125 (CA125), and cytoke...
A Bibliometric Analysis of a New System for Treating Critically Ill Patients Based on CiteSpace
Xiaomei SU, Xuelin DENG, Hao XIE, Yang Shuyu ZHANG, Lan SHEN, Chaoming CHEN
2024, 45(10): 61-66. doi: 10.12259/j.issn.2095-610X.S20241010
Abstract(326) HTML PDF(8)
Abstract:
Objective To understand the current state of research, hot topics, and future trends in the treatment of critically ill patients based on CiteSpace. Methods Relevant literatures in CNKI database from 2020 to 2023 were retrieved and CiteSpace was used...
A Clinical Analysis of BFMCs Vertebroplasty vs PKP in Treating Osteoporotic Vertebral Compression Fractures
Heng DING, Fan ZHANG, Yuan ZHANG, ZhenKai LOU, Hongkun LI, Yu LEI, Xingguo LI
2024, 45(10): 67-74. doi: 10.12259/j.issn.2095-610X.S20241011
Abstract(431) HTML PDF(12)
Abstract:
Objective To explore the clinical efficacy of BFMC vertebroplasty versus PKP in treating OVCF. Methods A total of 290 patients diagnosed with OVCF at the First Affiliated Hospital of Kunming Medical University from September 2022 to November 2023 we...
Abnormal Clinical Features and Prognosis of ACTH in Pediatric Acute B Lymphocytic Leukemia
Qi NIE, Li LIU, Yue TIAN, Xiaoyan MAO, Qulian GUO, Xin TIAN
2024, 45(10): 75-84. doi: 10.12259/j.issn.2095-610X.S20241012
Abstract(793) HTML PDF(10)
Abstract:
Objective To explore the clinical characteristics and prognosis of acute B lymphocytic leukemia in children with abnormal adrenal corticotropic hormone (ACTH). Methods A total of 154 children with B-ALL admitted to the hematology Department of Kunmi...
Relationship between Serum IL-6,Cys C,and TNF-α and Sarcopenia in Patients with Chronic Kidney Disease and Its Impact on Patient Mortality Risk
Yutao WANG, Juan LIU
2024, 45(10): 85-90. doi: 10.12259/j.issn.2095-610X.S20241013
Abstract(268) HTML PDF(13)
Abstract:
Objective To investigate the relationship between serum interleukin-6 (IL-6), cystatin C (Cys C), tumor necrosis factor-α (TNF-α) and sarcopenia in patients with chronic kidney disease (CKD), and its impact on mortality risk. Methods A retrospective ...
Correlation between the Psychological Status and Self-Management Ability of Patients on Continuous Ambulatory Peritoneal Dialysis
Yating LEI, Junling ZHANG, Zhu ZHOU, Ting LUO, Xiaohua ZHU
2024, 45(10): 91-95. doi: 10.12259/j.issn.2095-610X.S20241014
Abstract(683) HTML PDF(10)
Abstract:
Objective To study the psychological state and self-management skills of peritoneal dialysis patients and to examine the factors influencing them and their interrelationships. Methods A convenience sampling method was used, and general information s...
Effect of Ommaya Capsule on Cerebral Hemorrhage Complicated with Acute Hydrocephalus and its Effect on Blood-brain Barrier Function
Xinbang WANG, An HU, Xipeng ZHAO, Yan WANG, Wei DING, Lipeng CAO, Yu GU, Ke XU, Yunfeng ZHANG
2024, 45(10): 96-104. doi: 10.12259/j.issn.2095-610X.S20241015
Abstract(354) HTML PDF(11)
Abstract:
Objective To investigate the application of Ommaya capsule in the treatment of cerebral hemorrhage complicated with acute hydrocephalus and its effect on blood-brain barrier function and prognosis. Methods A total of 80 patients with cerebral hemorr...
Predictive Value of Serum and Tissue miR-205 for Postoperative Recurrence of Ovarian-type Endometriosis
Peilin CUI, Yuxia SONG, Xuejuan WANG
2024, 45(10): 105-110. doi: 10.12259/j.issn.2095-610X.S20241016
Abstract(317) HTML PDF(9)
Abstract:
Objective To explore the predictive value of serum and tissue miR-205 for postoperative recurrence of ovarian-type endometriosis (EMT). Methods A total of 100 patients with ovarian-type EMT who were treated at Shijiazhuang People's Hospital from Jun...
Correlation Between KL-6,IL-17 and CTD-ILD
Xingxu LIU, Meihua LI, Chaofeng REN, Weiping WANG, Li LI, Yuan BO, Chunmei ZHANG, Jing JIANG, Zhangmin ZHENG, Dongyu ZHOU
2024, 45(10): 111-115. doi: 10.12259/j.issn.2095-610X.S20241017
Abstract(283) HTML PDF(7)
Abstract:
Objective To compare the expression levels of KL-6 and IL-17 in CTD-ILD and CTD, to explore the diagnostic value of KL-6 and IL-17 in CTD-ILD, and to analyze the correlation between KL-6 and IL-17 and pulmonary diffusion function, provide a basis for...
Application Value of HBP and PLR in AECOPD
Jing JIANG, Meihua LI, Lifen YANG, Chaofeng REN, Yalin ZHAO, Xingxu LIU, Dongyu ZHOU, Zhangmin ZHENG
2024, 45(10): 116-121. doi: 10.12259/j.issn.2095-610X.S20241018
Abstract(623) HTML PDF(4)
Abstract:
Objective To investigate the relationship between heparin binding protein (HBP) and platelet-to-lymphocyte ratio (PLR) and acute exacerbation of chronic obstructive pulmonary disease (AECOPD), and evaluate their clinical value in the prediction and d...
Association between Body Mass Index and Cognitive Impairment in the Elderly in Guandu District of Kunming City
Qinghua YI, Juan XU, Ailian LI, Linyun TIAN, Dongli SANG, Jing XIONG, Chang DENG
2024, 45(10): 122-129. doi: 10.12259/j.issn.2095-610X.S20241019
Abstract(295) HTML PDF(13)
Abstract:
Objective To explore the association between body mass index (BMI) and cognitive impairment in the elderly in Guandu district of Yunnan province. Methods The data were collected from the community health check-ups for elderly individuals in Guandu D...
Frailty and Related Factors in Elderly Patients with Chronic Pain
Xuesong HU, Wenbin DONG, Shifu LI, Liyue CHEN, Yingzhou MIAO, Bing SHEN, WenRui ZHOU, Shaoxing DONG
2024, 45(10): 130-134. doi: 10.12259/j.issn.2095-610X.S20241020
Abstract(259) HTML PDF(8)
Abstract:
Objective To understand the frailty of elderly patients with chronic pain and its related influencing factors. Methods A face-to-face survey using a simple random sampling method was conducted for elderly patients with chronic pain at a grade-A tert...
Analysis of Results from AI-Assisted Cervical Cancer Screening for Rural Women in Baoding City
Xiaoxiao ZHANG, Lulu LIU, Feng YAN, Jinlan YANG, Zhiqiang WANG, Meili HU
2024, 45(10): 135-139. doi: 10.12259/j.issn.2095-610X.S20241021
Abstract(250) HTML PDF(4)
Abstract:
Objective To analyze the data of the artificial intelligence cervical cancer screening project in Baoding in 2021, understand the effect and existing problems of cervical cancer screening in Baoding, and provide a basis for improving the prevention a...
AIDS Research
Risk Assessment and Analysis of Risk Factors for Cardiovascular Disease in HIV Antiviral Therapy Patients
Yihan LIU, Jun LIU, Yongmei JIN, Bo TIAN, Jinsong BAI
2024, 45(10): 140-146. doi: 10.12259/j.issn.2095-610X.S20241022
Abstract(764) HTML PDF(13)
Abstract:
Objective To assess the risk of cardiovascular disease (CVD) in patients undergoing antiretroviral therapy (ART), to understand the differences among patients with different risk levels in Kunming, and to analyze the risk factors affecting CVD. Meth...
Reviews
Prospects of Fecal Microbiota Transplantation for Inflammatory Bowel Disease in the Context of Biological Agents
Zhongshun NIE, Yinglei MIAO
2024, 45(10): 147-154. doi: 10.12259/j.issn.2095-610X.S20241023
Abstract(527) HTML PDF(29)
Abstract:
Inflammatory bowel disease (IBD) is a chronic, non-specific inflammatory condition of the intestines, and its mechanisms are still unclear, with effective treatments lacking. The advent of biologics has opened a new chapter in the treatment of IBD, w...
Application and Research Progress of Drugs in Intestinal Preparation before Colonoscopy in Children
Yilin DAI, Yunfen TIAN
2024, 45(10): 155-159. doi: 10.12259/j.issn.2095-610X.S20241024
Abstract(691) HTML PDF(11)
Abstract:
Colonoscopy allows observing the condition of the intestinal mucosa and diagnose and treat abnormal lesions inside the colon early. And intestinal preparation can provide a clear intestinal view by clearing feces and other residual impurities in the ...
Teaching Research
'Four-in-One’ Teaching Model Promotes the Effectiveness of Clinical Practice Teaching in Emergency Medicine
Li YANG, Wen YU, Ying WANG, Linbo WANG, Yongjie HUANG, Jinglin LI
2024, 45(10): 160-165. doi: 10.12259/j.issn.2095-610X.S20241025
Abstract(624) HTML PDF(18)
Abstract:
Objective To explore the effectiveness of the "four-in-one" teaching model in clinical practice teaching of emergency medicine. Methods A total of 200 students from the Class of 2022 in the Clinical Medicine program at Kunming Medical University wer...
Nursing Forum
Application of Knowledge-attitude-behavior Continuation in Nursing Education for Nasopharyngeal Cancer Patients After Radiotherapy and Chemotherapy
Jiang WU, Jiang ZHANG, Yanyan FEI, Qin LIU, Yuanjiao CHEN, Yuanxiao WANG, Shuifen DAI
2024, 45(10): 166-172. doi: 10.12259/j.issn.2095-610X.S20241026
Abstract(415) HTML PDF(8)
Abstract:
Objective To investigate the impact of continued care education on knowledge, attitude, and behavior after radiochemotherapy in patients with nasopharyngeal carcinoma (NPC) on their nutritional status, limited mouth opening, and quality of life. Met...
Effects of Diversified Health Education on Quality of Life and Anxiety in Patients Undergoing Periodontal Accelerated Osteogenic Orthodontic Surgery
Yingbi TAO, Qiuju ZHAI, Sijia MA, Mingzhu ZHANG
2024, 45(10): 173-178. doi: 10.12259/j.issn.2095-610X.S20241027
Abstract(324) HTML PDF(5)
Abstract:
Objective To investigate the impact of diverse health education on patients' quality of life and anxiety after periodontally accelerated osteogenic orthodontics (PAOO) surgery, providing clinical evidence for exploring better health education models....
Mediating Role of Resilience between Emotional Labor,Work Engagement,and Burnout among Ward Nurses
Jingjing WU, Fangzhou GUO, Haiyan XIONG, Wenlong HUANG, Peihong FANG, Xiaofang ZHOU
2024, 45(10): 179-188. doi: 10.12259/j.issn.2095-610X.S20241028
Abstract(633) HTML PDF(20)
Abstract:
Objective To explore the relationship between emotional labor, work engagement, and burnout among ward nurses, and the mediating role of resilience. Methods From October to November 2022, a stratified random sampling method was used to select 240 wa...