2024 Vol. 45, No. 11
2024, 45(11): 1-8.
doi: 10.12259/j.issn.2095-610X.S20241122
Abstract:
Food safety is a major public health problem in the world. Foodborne pathogens are the main factors threatening human health and food safety. Rapid and accurate detection of foodborne pathogens is of great significance to ensure food safety and preve...
Food safety is a major public health problem in the world. Foodborne pathogens are the main factors threatening human health and food safety. Rapid and accurate detection of foodborne pathogens is of great significance to ensure food safety and preve...
Expression Analysis of WDR36 and WRN Genes of Borrelia Burgdorferi in HMC3 Cell Line Infection Model
2024, 45(11): 9-15.
doi: 10.12259/j.issn.2095-610X.S20241102
Abstract:
Objective The aim is to explore the molecular mechanism of neurological Lyme disease, particularly by identifying two differentially expressed genes WDR36 and WRN associated with Burkholderia infection through transcriptome analysis. Secondly, to ver...
The Association of HOXD-AS2 and MIR3142HG Gene Polymorphisms with Cervical Intraepithelial Neoplasia
2024, 45(11): 16-21.
doi: 10.12259/j.issn.2095-610X.S20241103
Abstract:
Objective To explore the association of HOXD-AS2 and MIR3142HG gene polymorphism with cervical intraepithelial neoplasia (CIN). Methods Two single nucleotide polymorphisms (SNPs) located in HOXD-AS2 (rs1348808) and located in MIR3142HG (rs2431099) w...
2024, 45(11): 22-30.
doi: 10.12259/j.issn.2095-610X.S20241104
Abstract:
Objective To explore the molecular mechanism of miR-212-3p in glioma cell proliferation, invasion and epithelial-mesenchymal transition (EMT). Methods The expression of miR-212-3p and NAP1L1 were detected by RT-qPCR in glioma cells. NC mimic, miR-21...
2024, 45(11): 31-37.
doi: 10.12259/j.issn.2095-610X.S20241105
Abstract:
Objective To explore the protective effects of Xiyanping injection against lipopolysaccharide (lipopolysaccharide, LPS)-induced acute lung injury (acute lung injury, ALI)in mice, and preliminarily investigate its mechanism. Methods The mice were ran...
2024, 45(11): 38-45.
doi: 10.12259/j.issn.2095-610X.S20241106
Abstract:
Objective To establish in vivo rat ischemic myocardial injury and in vitro cardiac microvascular endothelial cell (CMEC) hypoxia models so as to investigate the structural and biological changes and probe the angiogenesis basis of coronary microcircu...
2024, 45(11): 46-51.
doi: 10.12259/j.issn.2095-610X.S20241107
Abstract:
Objective To explore the regulatory mechanism of TLR4/NF-κB/MUC5B in allergic rhinitis. Methods A mouse model of allergic rhinitis was established to observe the changes in pathological characteristics of the model and to detect the expression of TLR...
2024, 45(11): 52-58.
doi: 10.12259/j.issn.2095-610X.S20241108
Abstract:
Objective The purpose of the study is to understand the exposure of rural women to pyrethroid pesticides during each pregnancy stage. Methods From December 2014 to December 2016, 216 pregnant and postpartum women with the average age between 24.81±5...
2024, 45(11): 59-66.
doi: 10.12259/j.issn.2095-610X.S20241109
Abstract:
Objective To analyze the research hotspots and frontiers of symptom clusters of hepatocarcinoma patients. Methods The relevant literatures on liver cancer symptom cluster research collected by CNKI since 1987 were searched, and a total of 100 releva...
2024, 45(11): 67-72.
doi: 10.12259/j.issn.2095-610X.S20241110
Abstract:
Objective To analyze the factors influencing physician job burnout. Methods A multistage stratified random sampling method was adopted to select a total of 1190 physicians from 10 public general hospitals above the second level in 5 regions of Yunna...
2024, 45(11): 73-80.
doi: 10.12259/j.issn.2095-610X.S20241111
Abstract:
Objective To investigate the current situation of medical cooperation and nurses' work engagement of dental specialty nurses in Yunnan province, and to explore the impact of medical cooperation on the work engagement of dental specialty nurses. Meth...
2024, 45(11): 81-86.
doi: 10.12259/j.issn.2095-610X.S20241112
Abstract:
Objective To explore the causal relationship between nut intake and chronic obstructive pulmonary disease by two-sample Mendelian randomization method. Methods SNP loci closely related to nut intake was extracted from the summarized large sample ope...
2024, 45(11): 87-94.
doi: 10.12259/j.issn.2095-610X.S20241113
Abstract:
Objective To analyze the risk factors of EB virus (EBV) and cytomegalovirus (CMV) infections in patients with ulcerative colitis (UC) and their relationship with drug efficacy. Methods A retrospective analysis was conducted on clinical data from 280 ...
2024, 45(11): 95-102.
doi: 10.12259/j.issn.2095-610X.S20241114
Abstract:
Objective To investigate the effects of dapagliflozin on cardiac structure and function in patients with heart failure due to mildly reduced ejection fraction. Methods Patients diagnosed with heart failure due to mildly reduced ejection fraction in ...
2024, 45(11): 103-109.
doi: 10.12259/j.issn.2095-610X.S20241128
Abstract:
Objective To summarize the case data of patients with primary liver neuroendocrine tumors (PHNET) and analyze their clinical characteristics, imaging manifestations, pathological characteristics, and diagnosis and treatment status so as to improve th...
2024, 45(11): 110-116.
doi: 10.12259/j.issn.2095-610X.S20241115
Abstract:
Objective To investigate preliminarily the causes of elevated ferritin in patients with hemophagocytic syndrome by analyzing the iron metabolism indexes, liver function and cytokine levels. Methods 41 patients with the hemophagocytic syndrome and an...
2024, 45(11): 117-124.
doi: 10.12259/j.issn.2095-610X.S20241116
Abstract:
Objective To study the effect of ORM1 on sphingolipid metabolism in dry eye via SPTLC1 so as to provide a new research direction for the pathogenesis of dry eye. Methods By the subcutaneous injection of scopolamine hydrobromide (SCOP), a dry eye mod...
The Effects of NLR,PLR,and FRA in Peripheral Blood on Normal Bone Mass and Bone Loss after Fractures
2024, 45(11): 125-129.
doi: 10.12259/j.issn.2095-610X.S20241117
Abstract:
Objective To investigate the effects of neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and fibrin/albumin ratio in systemic inflammatory markers on bone loss and normal bone function after fractures. Methods A retrospective study was conduc...
2024, 45(11): 130-136.
doi: 10.12259/j.issn.2095-610X.S20241118
Abstract:
Objective To investigate the relationship between the biochemical indexes of bone metabolism and gender, age and season in adult residents. Methods The data of 6462 cases of physical examination in the physical examination center of the First Affili...
2024, 45(11): 137-143.
doi: 10.12259/j.issn.2095-610X.S20241119
Abstract:
Objective To investigate the clinical features, independent risk factors, and antibiotic selection in children with acute leukemia complicated by multidrug-resistant (multiple resistant bacteria, MDR) bloodstream infections. Methods A retrospective ...
2024, 45(11): 144-148.
doi: 10.12259/j.issn.2095-610X.S20241120
Abstract:
Objective To observe the effect of the delay of myopia in children wearing composite multi-point optical defocusing lens. Methods A total of 52 cases (n = 104) of monocal lens wearers were selected as the control group, and 78 cases (n = 156) of com...
2024, 45(11): 149-154.
doi: 10.12259/j.issn.2095-610X.S20241121
Abstract:
Objective To investigate the current status of metabolic syndrome (MS) in ART patients and analyze its influencing factors. Methods Data from 1972 ART patients were collected and the prevalence of MS was determined according to the diagnostic guidel...
2024, 45(11): 155-160.
doi: 10.12259/j.issn.2095-610X.S20241101
Abstract:
Diabetes often coexists with cardiovascular complications, which are also a common cause of death in diabetes patients. Therefore, in addition to improving glucose metabolism, it is also necessary to control cardiovascular complications in diabetes p...
Diabetes often coexists with cardiovascular complications, which are also a common cause of death in diabetes patients. Therefore, in addition to improving glucose metabolism, it is also necessary to control cardiovascular complications in diabetes p...
2024, 45(11): 161-165.
doi: 10.12259/j.issn.2095-610X.S20241123
Abstract:
With the deepening development of molecular biology, people's understanding of the mechanisms of cancer occurrence is becoming increasingly profound. In recent years, DDX46 has been found to be overexpressed in various cancers such as colorectal canc...
With the deepening development of molecular biology, people's understanding of the mechanisms of cancer occurrence is becoming increasingly profound. In recent years, DDX46 has been found to be overexpressed in various cancers such as colorectal canc...
2024, 45(11): 166-173.
doi: 10.12259/j.issn.2095-610X.S20241124
Abstract:
Objective To explore the intervention effect of an evaluation index system based on the comprehensive evaluation (CE) on undergraduate academic mentorship. Methods Delphi method and Analytic Hierarchy Process were used to determine the evaluation in...
2024, 45(11): 174-180.
doi: 10.12259/j.issn.2095-610X.S20241125
Abstract:
Objective To investigate the effect of health education under the guidance of cognitive behavioral therapy in the virtual community care of patients with colorectal cancer chemotherapy intermittent. Methods 74 colorectal cancer patients who underwen...
2024, 45(11): 181-185.
doi: 10.12259/j.issn.2095-610X.S20241126
Abstract:
Objective To study the construction and application effect of PBL teaching model combined with the scenario simulation teaching method in the nursing first aid course for generalized tonic-clonic seizure (GTCS) attacks. Methods A total of 120 nursin...
2024, 45(11): 186-190.
doi: 10.12259/j.issn.2095-610X.S20241127
Abstract:
Objective To explore the application effect of parallel medical record writing in practice teaching of nursing students. Methods From September 2021 to February 2022, 58 nursing students who practiced in a Grade A hospital in Xiangyang City were sel...