2024 Vol. 45, No. 12
2024, 45(12): 1-9.
doi: 10.12259/j.issn.2095-610X.S20241201
Abstract:
Caloric restriction (CR) and intermittent fasting (IF) are two dietary intervention strategies that have garnered increasing attention for their potential role in regulating inflammation and metabolic disorders. With the widespread adoption of high-c...
Caloric restriction (CR) and intermittent fasting (IF) are two dietary intervention strategies that have garnered increasing attention for their potential role in regulating inflammation and metabolic disorders. With the widespread adoption of high-c...
2024, 45(12): 10-18.
doi: 10.12259/j.issn.2095-610X.S20241202
Abstract:
Objective To study the therapeutic effect and mechanism of geraniin on experimental osteoporotic fracture (OPF) in rabbits. Methods Rabbits were randomly divided into sham operation group, model group, different doses of geraniin groups ( 20, 10, 5 ...
2024, 45(12): 19-27.
doi: 10.12259/j.issn.2095-610X.S20241203
Abstract:
Objective To explore the role and mechanism of crocin in pituitary adenoma (PA) through clinical samples and related molecular biology experiments of HP75 cells. Methods From June 2022 to May 2023, 16 PA samples were collected from the Second Depart...
2024, 45(12): 28-34.
doi: 10.12259/j.issn.2095-610X.S20241204
Abstract:
Objective To investigate the stability of the two kinds of rat models of chronic renal failure, aiming to provide a basis for establishing a feasible and stable animal model of chronic renal failure. Methods The rat model of chronic renal failure wa...
2024, 45(12): 35-41.
doi: 10.12259/j.issn.2095-610X.S20241205
Abstract:
Objective By assessing the uncertainty of the determination results for the concentration of ambroxol hydrochloride injection, the reliability of the concentration measurement results is improved, ensuring the safety and efficacy of high-risk dosage ...
2024, 45(12): 42-48.
doi: 10.12259/j.issn.2095-610X.S20241206
Abstract:
Objective To investigate the expression of spalt like transcription factor 4 (Sall4) in pancreatic cancer tissues and its clinical significance, as well as the impact of inhibiting its gene expression on the migration and invasion of pancreatic cance...
2024, 45(12): 49-57.
doi: 10.12259/j.issn.2095-610X.S20241207
Abstract:
Objective To study the pathogenesis of psoriasisand and to provide new research ideas and directions for the prevention and treatment of psoriasis. Methods Psoriasis-related genes were obtained from genecards and NCBI databases, and intersection gen...
2024, 45(12): 58-64.
doi: 10.12259/j.issn.2095-610X.S20241208
Abstract:
Objective To investigate the factors associated with atrial fibrillation(AF) in patients with Type 2 Diabetes Mellitus (T2DM). Methods Through a case-control study, We selected 688 patients with T2DM who were hospitalized at the First Affiliated Hos...
2024, 45(12): 65-74.
doi: 10.12259/j.issn.2095-610X.S20241209
Abstract:
Objective Immune infiltration, as well as their implications across various cancers, and to establish a clinical prognostic model based on the findings. Methods The expression profile and clinical information of endometrial cancer tissue and adjacent...
2024, 45(12): 75-80.
doi: 10.12259/j.issn.2095-610X.S20241210
Abstract:
Objective To investigate the clinical features of the spectrum of upper gastrointestinal diseases in children and to provide assistance in the prevention, diagnosis and treatment of upper gastrointestinal diseases in children. Methods Clinical data ...
2024, 45(12): 81-87.
doi: 10.12259/j.issn.2095-610X.S20241211
Abstract:
Objective To explore the efficacy of the geriatric interdisciplinary team (GIT) service for elderly patients with multimorbidity and malnutrition. Methods We selected 109 elderly patients with diabetes mellitus (DM), chronic obstructive pulmonary di...
2024, 45(12): 88-93.
doi: 10.12259/j.issn.2095-610X.S20241212
Abstract:
Objective To investigate the status of perceived discrimination among HIV-infected people receiving antiviral treatment and analyze its influencing factors, so as to provide reference for reducing discrimination and improving the life quality of HIV-...
2024, 45(12): 94-98.
doi: 10.12259/j.issn.2095-610X.S20241213
Abstract:
Objective To analyze the prognostic value of preoperative peripheral blood inflammatory markers neutrophil to lymphocyte ratio (NLR) combined with tumor markers carcinoembryonic antigen (CEA) and glycoprotein antigen CA19-9 in patients with colon can...
2024, 45(12): 99-104.
doi: 10.12259/j.issn.2095-610X.S20241214
Abstract:
Objective To explore the influence of different factors on the safe screw placement of the ulnar coronoid process based on the DR imaging measurement of the ulnar coronoid process. Methods During the period from July 2020 to November 2021, 102 norma...
2024, 45(12): 105-114.
doi: 10.12259/j.issn.2095-610X.S20241215
Abstract:
Objective To identify potential biomarkers associated with LN, with the goal of improving early diagnosis, disease monitoring, and the development of more precise treatment strategies. Methods Gene expression data were downloaded from the Gene Expre...
2024, 45(12): 115-121.
doi: 10.12259/j.issn.2095-610X.S20241216
Abstract:
Objective To investigate the correlation between biofilm gene, efflux pump gene, biofilm forming ability and drug resistance of Acinetobacter baumarmii (AB) isolated from the patients of clinical infectious diseases. Methods A total of 119 non-repea...
2024, 45(12): 122-128.
doi: 10.12259/j.issn.2095-610X.S20241217
Abstract:
Objective To investigate the relationship between peripheral blood immunoglobulin, erythrocyte sedimentation rate (ESR), homocysteine (Hcy) and the severity of central nervous system vasculitis (CNSV) in children, as well as its impact on prognosis. ...
2024, 45(12): 129-134.
doi: 10.12259/j.issn.2095-610X.S20241218
Abstract:
Objective To explore the early predictive value of lymphocyte subsets for cognitive impairment in cerebral ischemia-reperfusion injury. Methods A study was conducted on 68 patients with cerebral ischemia admitted to Honghe Hospital affiliated to Kun...
2024, 45(12): 135-140.
doi: 10.12259/j.issn.2095-610X.S20241219
Abstract:
Objective To investigate the correlation between the levels of soluble vascular endothelial growth factor receptor-1 (sFlt-1), polyligand proteoglycan-4 (SDC4), soluble human stromal lysin 2 (sST2) in serum and renal histopathological grading in chil...
2024, 45(12): 141-146.
doi: 10.12259/j.issn.2095-610X.S20241220
Abstract:
Objective To explore the clinical application of salpingectomy with preserving salpingum mesothelium under single-port laparoscopy and its influence on ovarian reserve function and assisted pregnancy outcome. Methods From January 2019 to January 202...
2024, 45(12): 147-152.
doi: 10.12259/j.issn.2095-610X.S20241221
Abstract:
Objective To investigate the correlation between serum hepatitis B core anbody (anti-HBC), cholinesterase (CHE) and apolipoprotein AI (ApoAI) and the development of viral hepatitis. Methods 388 patients with viral hepatitis admitted to Nanjing Pukou...
2024, 45(12): 153-159.
doi: 10.12259/j.issn.2095-610X.S20241222
Abstract:
Objective To study the relationship between lipid metabolism and liver function indexes in prediabetic population, and explore the predictive value of these indexes for prediabetes. Methods 546 patients with prediabetes who underwent physical examin...
2024, 45(12): 160-166.
doi: 10.12259/j.issn.2095-610X.S20241223
Abstract:
Intestinal flora and their metabolites play an important role in the occurrence and development of cardiovascular diseases such as atherosclerosis (AS), and have become an important target for the prevention and treatment of AS. In this paper, we foc...
Intestinal flora and their metabolites play an important role in the occurrence and development of cardiovascular diseases such as atherosclerosis (AS), and have become an important target for the prevention and treatment of AS. In this paper, we foc...
2024, 45(12): 167-171.
doi: 10.12259/j.issn.2095-610X.S20241224
Abstract:
Keloids are benign skin lesions that form during the wound healing process due to abnormal proliferation of fibroblasts and excessive extracellular matrix deposition. It is reported that 86% of keloid patients experience pruritus; however, the sympto...
Keloids are benign skin lesions that form during the wound healing process due to abnormal proliferation of fibroblasts and excessive extracellular matrix deposition. It is reported that 86% of keloid patients experience pruritus; however, the sympto...
2024, 45(12): 172-177.
doi: 10.12259/j.issn.2095-610X.S20241225
Abstract:
Objective To explore the application of the "learning by doing" learning theory and methods in the teaching of Obstetrics and Gynecology Nursing for undergraduate nursing students. Method By setting up an experimental group of 151 students and a con...
2024, 45(12): 178-184.
doi: 10.12259/j.issn.2095-610X.S20241226
Abstract:
Objective To investigate the current demand for extended nursing services for newborns after discharge. Methods A survey was conducted on the demand for extended nursing services after discharge of newborns using the "Survey Form for Demand for Exten...