2024 Vol. 45, No. 3

Expert Forum
Entropy、Dissipative Structure And Health
Sifan DUAN, Mengmei LIU, Yani LI, Dingyun YOU
2024, 45(3): 1-6. doi: 10.12259/j.issn.2095-610X.S20240301
Abstract(1345) HTML PDF(49)
Abstract:
Dissipative structure refers to a self-organized and orderly structure that exists far from equilibrium. The human body, considered a classical example, generates negative entropy through the exchange of matter, energy, and information with the envir...
Original Articles Basic of Medicine
Association of Polymorphisms in the 3' UTR of Genes in the ERK1/2 Signaling Pathway with Non-small Cell Lung Cancer
Chao HONG, Xudong XIANG, Yingfu LI, Yang CAO, Xueya CHEN, Shuai LI, Anhao XING, Mu LIN, Qianli MA
2024, 45(3): 7-17. doi: 10.12259/j.issn.2095-610X.S20240302
Abstract(1088) HTML PDF(41)
Abstract:
Objective To investigate the association between four single nucleotide polymorphisms(SNP)(rs9340 in MAPK1, rs14804 in NRAS, rs712 and rs7973450 in KRAS) in the 3'UTR of ERK1/2 signaling pathway-related genes and non-small cell lung cancer(NSCLC). M...
Identification of Atrial Fibrillation-related Inflammatory Genes and Their Association with Immune Cell Infiltration Based on Comprehensive Bioinformatic Analysis
Man YANG, Xingan ZHAO, Yunna GE, Juan QIN, Xiya WANG, Siming TAO
2024, 45(3): 18-29. doi: 10.12259/j.issn.2095-610X.S20240303
Abstract(1247) HTML PDF(30)
Abstract:
Objective To identify inflammation-related genes in atrial fibrillation (AF) and explore the possible role and mechanism of these genes and infiltrating immune cells in the development of AF. Methods A series of bioinformatics analysis combined with...
The “Window Effect” Study on the Effect of 1800 MHz Electromagnetic Radiation Irradiation on GFAP Expression in the Hippocampus of Rats
Xiaoshuang XU, Qing XIONG, Yuan ZHANG, Huixin WU, Limei HE, Yunzhen MU
2024, 45(3): 30-34. doi: 10.12259/j.issn.2095-610X.S20240304
Abstract(1411) HTML PDF(10)
Abstract:
Objective To investigate the effect of electromagnetic wave power density on the expression of glial fibrillary acidic protein(GFAP) in the hippocampus of SD rats under 1800 MHz electromagnetic wave irradiation, and whether it exhibits a “window effe...
Propofol Regulates MPP+-induced Mitochondrial Oxidative Stress and Apoptosis in SH-SY5Y Cells
Ying TAN, Haiyan QIN, Xiang SUN, Yanyi SU, Yingbao WANG
2024, 45(3): 35-41. doi: 10.12259/j.issn.2095-610X.S20240305
Abstract(1272) HTML PDF(36)
Abstract:
Objective To investigate the effects of different concentrations of PPF on oxidative stress and apoptosis of PD model cells induced by MPP+. Methods The human neuroblastoma cell SH-SY5Y was induced by 1 mM MPP+ to establish PD cell model. In PPF tre...
Clinical Research
A Cross-sectional Study on the Cognitive Status of Cardiopulmonary Resuscitation among Urban and Rural Residents in Tonghai County
Zihan AI, Siman LI, Shengguo ZAO, Mingrui CHEN, Yinhe ZHOU, Sijia HUANG, Haidi DING, Ranxi SHI, Qiuyi ZHANG, Jun YANG
2024, 45(3): 42-47. doi: 10.12259/j.issn.2095-610X.S20240306
Abstract(1419) HTML PDF(11)
Abstract:
Objective To investigate the popularization of cardiopulmonary resuscitation(CPR) knowledge and science popularization needs among urban and rural residents in Tonghai County, Yuxi City, Yunnan Province, so as to explore the establishment of an effic...
Interventional Treatment of Muscular Ventricular Septal Defect in Children
Wei HU, Jinnan LI, Wei YANG, Li SU, Zhuo YU, Zhisong CHEN
2024, 45(3): 48-53. doi: 10.12259/j.issn.2095-610X.S20240307
Abstract(1257) HTML PDF(13)
Abstract:
Objects To explore the effectiveness and safety of using the Cardio-O-Fix Plug occluder in the treatment of muscular ventricular septal defect(mVSD) in children. Methods 14 patients with mVSD were taken to the cardiology department of First Affilia...
Prospective Clinical Study of Combined Treatment of Periodontal Orthodontics for Chronic Periodontitis
Lili YANG, Ting ZHOU, Xiaobin REN, Jianhua WU, Yi PENG, Yanqing SHUI
2024, 45(3): 54-58. doi: 10.12259/j.issn.2095-610X.S20240308
Abstract(1126) HTML PDF(20)
Abstract:
Objective To investigate the effect of dynamic monitoring of occlusal force on the final therapeutic effect and the change of periodontal supporting tissue during combined periodontal orthodontic treatment. Methods The periodontal clinical index of ...
Value of Head and Neck 4D-CTA Combined with SDF-1a/CXCR4 Signaling Pathway in Assessing the Risk of Ruptured Intracranial Posterior Communicating Aneurysms
Yiming XU, Jianfeng ZHONG, Bin LI, Xinyan ZHOU, Hongli ZHU, Jing LIANG, Chengde LIAO
2024, 45(3): 59-64. doi: 10.12259/j.issn.2095-610X.S20240309
Abstract(790) HTML PDF(13)
Abstract:
Objective To investigate the value of 4D-CTA combined with SDF-1a/CXCR4 signaling pathway in evaluating the risk of intracranial aneurysm rupture. Methods Fifty patients with unruptured intracranial posterior communicating aneurysms and 50 patients ...
Correlation Between TyG Index,MHR and Coronary Lesions,Myocardial Ischemia in Patients with Coronary Heart Disease,and the Value of Combined Detection
Shuangshuang XU, Wei ZHAO, Lei JIANG, Huajiang LIU, Fang WANG, Zhisheng TAN, Likun ZHOU
2024, 45(3): 65-71. doi: 10.12259/j.issn.2095-610X.S20240310
Abstract(1203) HTML PDF(24)
Abstract:
Objective To investigate the correlation of triacylglycerol glucose(TyG) index, monocyte to high-density lipoprotein cholesterol ratio(MHR) with coronary artery disease and myocardial ischemia degree in coronary heart disease(CHD), and to analyze the...
Clinical Observation of Treating Ulcerative Colitis with Acupuncture at Front Mu Points Combined with Oral Mesalazine
Chunling LI, Linghua LI, Xu HAN, Jie YANG, Heng ZHANG
2024, 45(3): 72-78. doi: 10.12259/j.issn.2095-610X.S20240311
Abstract(814) HTML PDF(14)
Abstract:
Objective To observe the clinical efficacy of acupuncture at Front Mu point in the treatment of ulcerative colitis. Methods Sixty patients with ulcerative colitis treated at the Traditional Chinese Medicine Hospital in Kunming from August 2022 to Ju...
Influence of Medication Compliance of Type 2 Diabetes Chronic Disease Management Patients in Two Communities of Kunming on Disease Control
Xinlin ZHU, Yanan WU, Qi MENG, Qianzi YANG, Yuanbiao LI, Junheng TAO, Mengyang HE
2024, 45(3): 79-83. doi: 10.12259/j.issn.2095-610X.S20240312
Abstract(807) HTML PDF(8)
Abstract:
Objective To analyze the influence of medication compliance of chronic type 2 diabetes management patients on disease control in two communities in Kunming. Methods A total of 138 patients with type 2 diabetes who were included in chronic disease m...
Application Effect of A New Modified 3D PSI in Total Knee Arthroplasty for Knee Osteoarthritis
Qing HU, Chuan LI, Chong SHI, Mo RUAN, Jingze YANG
2024, 45(3): 84-91. doi: 10.12259/j.issn.2095-610X.S20240313
Abstract(837) HTML PDF(4)
Abstract:
Objective To explore the application effect of new improved 3D printing individualized guidance (3D psi) in total knee arthroplasty (TKA) for knee osteoarthritis (KOA). Methods A total of 100 patients with KOA in 920th Hospital of Joint Logistics Su...
Mental Health Status and Its Influencing Factors Among Elderly Hypertension Patients from Rural Areas of Chuxiong and Honghe Prefecture in Yunnan
Qichuan HU, Hechuan ZHANG, Lichun JIANG, Yajing ZHANG, Fujing FENG, Ximeng ZHAO, Yunxian WANG
2024, 45(3): 92-98. doi: 10.12259/j.issn.2095-610X.S20240314
Abstract(1740) HTML PDF(13)
Abstract:
Objective To investigate the mental health status and its influencing factors among elderly hypertensive patients from Rural Areas of Chuxiong and Honghe Prefecture in Yunnan. Methods Multi-stage random sampling method was adopted to select elderly...
Predictive Modeling of Chronic Kidney Disease with Hypertension or Diabetes Based on Machine Learning Algorithms
Huijuan ZENG, Bo TIAN, Hongling YUAN, Jie HE, Guanxi LI, Guojia RU, Min XU, Dong ZHAN
2024, 45(3): 99-105. doi: 10.12259/j.issn.2095-610X.S20240315
Abstract(1132) HTML PDF(34)
Abstract:
Objective To build the early predictive model for chronic kidney disease (CKD) in hypertension and diabetes patients in the community. Methods The CKD patients were recruited from 4 health care centers in 4 urban areas in Kunming. The control group ...
Value of SHOX2 and RASSF1A Gene Methylation in Alveolar Lavage Fluid in Patients with Pulmonary Nodules or Masses in the Diagnosis of Lung Cancer
Dongping ZHU, Haifeng LI, Junfei FENG, Qiuheng TANG, Jing LENG
2024, 45(3): 106-111. doi: 10.12259/j.issn.2095-610X.S20240316
Abstract(907) HTML PDF(9)
Abstract:
Objective The diagnostic efficacy of the two gene methylation indexes was verified by lung biopsy or postoperative disease examination results. Methods A prospective study was conducted to collect 99 patients diagnosed with pulmonary nodules and mas...
Correlation between Bone Density at Different Hip Positions with Muscle Parameters and Physical Performance in Middle-aged and Elderly People in Kunming Area
Meng GAO, Xingli LIU, Wei SONG, Liang LV, Gang WANG
2024, 45(3): 112-117. doi: 10.12259/j.issn.2095-610X.S20240317
Abstract(782) HTML PDF(8)
Abstract:
Objective To investigate the correlation between bone mineral density(BMD) at different hip positions with muscle parameters and physical performance in middle-aged and elderly people in Kunming area. Methods 531 middle-aged and elderly volunteers ...
Questionnaire Survey on General Medicine and Pre-hospital First Aid Knowledge Among People in Ludian County,Yunnan Province
Weiyu ZHOU, Dexing YANG, Qiang WANG, Zhenfang WANG, Kai FU, Jiefu TANG, Shengzhe LIU, Ying LUAN, Min LI, Rong LIU
2024, 45(3): 118-126. doi: 10.12259/j.issn.2095-610X.S20240318
Abstract(1660) HTML PDF(8)
Abstract:
Objective To explore the public's cognition and attitude towards general medicine, general practitioners, and pre-hospital first-aid knowledge in Ludian County, Yunnan Province, to find out the training and learning methods that are more acceptable t...
Relationship between TGF-β/Smads Signaling Pathway and Cognitive Dysfunction in Patients with Aneurysmal Subarachnoid Hemorrhage
Yi HUANG, Yongjian HUANG, Ling MAI, Ting LUO
2024, 45(3): 127-132. doi: 10.12259/j.issn.2095-610X.S20240319
Abstract(872) HTML PDF(7)
Abstract:
Objective To investigate the relationship between factors related to the transforming growth factor β(TGF-β)/Aerine-threonine kinase receptors(Smads) signaling pathway and cognitive dysfunction in peripheral blood of patients with aneurysmal subarach...
Risk Prediction of SBP in Patients with Primary Liver Cancer Complicated with Ascites
Hongyan WEI, Yuanzhen WANG, Lixian CHANG, Huan MU, Chunyun LIU, Li LIU
2024, 45(3): 133-140. doi: 10.12259/j.issn.2095-610X.S20240320
Abstract(915) HTML PDF(4)
Abstract:
Objective To explore the influencing factors of spontaneous bacterial peritonitis in patients with primary liver cancer complicated with ascites and establish a prediction model. Methods A total of 292 patients with primary liver cancer complicated...
Adverse Reactions of Vaccine Vaccination in Children with Special Health Conditions in Kunming and Countermeasures
Zhen XU, Yu LING, Sixiang LIU, Yu SONG, Yang PENG, Jingjing SUN
2024, 45(3): 141-145. doi: 10.12259/j.issn.2095-610X.S20240321
Abstract(1106) HTML PDF(12)
Abstract:
Objective To explore the occurrence of adverse reactions to vaccination in children with special health status in Kunming and the corresponding countermeasures. Methods The information data of 952 children with special health conditions who were vac...
Value of Three-dimensional Rectal Intraluminal Ultrasound Combined with Couplant Contrast for Surgical Guidance of Perianal Necrotising Fasciitis
Linghua LI, Xu HAN, Xueqin ZHANG, Xiaokun HUA, Chunling LI
2024, 45(3): 146-150. doi: 10.12259/j.issn.2095-610X.S20240322
Abstract(1259) HTML PDF(6)
Abstract:
Objective To explore the application value of Three-Dimensional rectal cavity ultrasound combined with contrast agent imaging in necrotizing fasciitis of the anal region. Methods Before surgery, standard three-dimensional rectal cavity ultrasound ex...
Predictive Value of Peripheral Blood Septin9 Gene Methylation Assay in Colorectal Adenoma
Juqing DENG, Lu YU, Liqiong LIAO, Zhongcun YANG
2024, 45(3): 151-156. doi: 10.12259/j.issn.2095-610X.S20240323
Abstract(1007) HTML PDF(13)
Abstract:
Objective To investigate the predictive significance of Septin9 gene methylation(mSEPT9) in peripheral blood in the diagnosis of colorectal adenoma. Methods A total of 52 subjects were included, 31 patients with colorectal adenomas were collected as...
Clinical Features and Prognostic Factors of 310 Patients with Antituberculosis Drug-induced Liver Injury
Xuejiao WU, Jiangli PENG, Hao FAN, Lu WANG, Jie CHEN, Hui LIU
2024, 45(3): 157-165. doi: 10.12259/j.issn.2095-610X.S20240324
Abstract(1284) HTML PDF(16)
Abstract:
Objective To analyze the clinical characteristics of 310 patients with anti-tuberculosis drug-induced liver injury (ATB-DILI), to explore prognostic influencing factors, and to provide reference for its prevention and treatment. Methods Primary tub...
Value of Multimodal Ultrasonography Combined with Clinical Indicators in Predicting the Progression of Ischemic Stroke
Li DONG, Rongping NING, Qiongyi XIAO
2024, 45(3): 166-173. doi: 10.12259/j.issn.2095-610X.S20240325
Abstract(1221) HTML PDF(15)
Abstract:
Objective To investigate the clinical value of multimodal ultrasonography combined with clinical indicators in predicting the progression of ischemic stroke (IS). Methods A total of 134 patients with IS admitted to Third People's Hospital of Yunnan...
Exploration of the Optimal Display Orientation of MR Plain and Arthrographic Images of Rotator Cuff Interstitial Structures
Kuan GENG, Guihua LI
2024, 45(3): 174-179. doi: 10.12259/j.issn.2095-610X.S20240326
Abstract(783) HTML PDF(6)
Abstract:
Objective To investigate the optimal display orientation of rotator cuff space(RI) structures on magnetic resonance(MR) scanning and arthrography. Methods A total of 80 patients who underwent MR scanning and arthrography in our hospital from January...
Reviews
Research Progress of Iron Death in Cardiomyopathy
Wei LI, Lihong JIANG, Lijing MA, Rui CHEN, Tongshuo YANG
2024, 45(3): 180-185. doi: 10.12259/j.issn.2095-610X.S20240327
Abstract(1263) HTML PDF(34)
Abstract:
Cardiomyopathy is a group of heterogeneous myocardial diseases with a variety of specific phenotypes that can lead to cardiovascular death or progressive heart failure in severe cases. Because of the severity and complexity of these diseases, the sea...
Research Progress on Aerobic Exercise Intervention for Learning and Memory Ability in Chronic Cerebral Ischemia
Haijun WANG, Liangwu QIU, Yanbin XIYANG, Jundi PANG
2024, 45(3): 186-191. doi: 10.12259/j.issn.2095-610X.S20240328
Abstract(1271) HTML PDF(20)
Abstract:
Active physical exercise can effectively alleviate the pathological process of chronic cerebral ischemia(CCH) and improve learning and memory ability. This paper reviews the possible biological mechanisms of aerobic exercise to delay the pathological...
Teaching Research
Application of Mini-CEX evaluation Model Based on OBE concept in Clinical Practice Teaching of Neurology DePartment
Yanping LI, Fei YANG, Qian OUYANG, Hongbin YU, Gang WU, Xiaolin DONG, Huan WEI, Qingyun LI, Yi ZENG
2024, 45(3): 192-197. doi: 10.12259/j.issn.2095-610X.S20240329
Abstract(1561) HTML PDF(30)
Abstract:
Objective To explore the application effect of the Mini-CEX evaluation model based on the OBE concept in the clinical Practice teaching of neurology. Methods We Selected 100 students who will Practice in the Department of Neurology from 2022 to 2023...
Nursing Forum
Study on Intravertebral Labor Analgesic Care with the Intervention of Anesthesia Nurse
Sisi CHENG, Chunmei YANG, Yaqun QUAN, Yawen LEI, Peixian DONG, Dandan YANG
2024, 45(3): 198-202. doi: 10.12259/j.issn.2095-610X.S20240330
Abstract(832) HTML PDF(10)
Abstract:
Objective To investigate the effect of intravertebral labor analgesia nursing intervened by anesthesia nurse on labor analgesia and delivery outcome. Methods Two hundreds cases of parturients who received intravertebral labor analgesia in The First ...