2024 Vol. 45, No. 4
2024, 45(4): 1-8.
doi: 10.12259/j.issn.2095-610X.S20240401
Abstract:
Inflammatory bowel disease (IBD) is a chronic condition characterised by recurrent inflammation of the intestines. Although the specific causes is not fully understood, it is generally believed to be caused by a combination of genetic factors, immune...
Inflammatory bowel disease (IBD) is a chronic condition characterised by recurrent inflammation of the intestines. Although the specific causes is not fully understood, it is generally believed to be caused by a combination of genetic factors, immune...
2024, 45(4): 9-16.
doi: 10.12259/j.issn.2095-610X.S20240402
Abstract:
Objective To construct a polygenic risk score based on the expression of epithelial cell markers to evaluate the prognosis of patients with ovarian cancer. Methods The single cell sequencing data of ovarian cancer were reduced and clustered to ident...
2024, 45(4): 17-25.
doi: 10.12259/j.issn.2095-610X.S20240403
Abstract:
Objective To construct a lipid metabolism-related prognostic model for ovarian cancer (OC), and to investigate the role of lipid metabolism-related biomarkers and the degree of immune cell infiltration in prognosis prediction of OC. Methods Transcri...
2024, 45(4): 26-34.
doi: 10.12259/j.issn.2095-610X.S20240404
Abstract:
Objective To compare the transdermal absorption of Bulleyaconitine A on normal rabbit intact skin, normal rabbit damaged skin, pathological damaged normal skin, and pathological damaged injured skin barrier models in vivo. Methods The rabbit model ...
2024, 45(4): 35-40.
doi: 10.12259/j.issn.2095-610X.S20240405
Abstract:
Objective To investigate the effect of cerebellar zinc finger structure 1 (ZIC1) gene overexpression on the proliferation and apoptosis of pleural mesothelioma cells (SMC-1 cells) and the corresponding molecular mechanism. Methods SMC-1 cells were t...
2024, 45(4): 41-48.
doi: 10.12259/j.issn.2095-610X.S20240406
Abstract:
Objective To test the reliability and validity of the Chronic Gastritis Patient Reported Outcomes(PROISCD-CG) scale, and to provide the scientific basis for evaluating the reported outcomes of chronic gastritis patients. Methods A questionnaire surv...
2024, 45(4): 49-56.
doi: 10.12259/j.issn.2095-610X.S20240407
Abstract:
Objective To analyze the 2-year screening myopia rate in Lijiang City and Dali City during the COVID-19 pandemic and analyze the related influencing factors of myopia. Methods A total of 774 students were randomly selected as the research subjects. ...
2024, 45(4): 57-61.
doi: 10.12259/j.issn.2095-610X.S20240408
Abstract:
Objective To study the correlation between the polymorphism of myeloperoxidase-463G/A gene and essential hypertension of Yi nationality in Yunnan Province. Methods The PCR-RFLP technique was used to detect the MPO-463G/A gene polymorphism in 86 Yi h...
2024, 45(4): 62-66.
doi: 10.12259/j.issn.2095-610X.S20240409
Abstract:
Objective To investigate the occurrence and related factors of depression, anxiety, and stress among oral medicine interns during their internship. Methods Using the DASS-21 scale, a survey was conducted among 120 undergraduate oral medicine student...
2024, 45(4): 67-73.
doi: 10.12259/j.issn.2095-610X.S20240410
Abstract:
Objective To explore the short-term efficacy, safety, and prognostic factors affecting the overall survival (OS) of patients with recurrent high-grade glioma (HGG) treated with bevacizumab (BEV) alone and bevacizumab in combination with temozolomide ...
2024, 45(4): 74-80.
doi: 10.12259/j.issn.2095-610X.S20240411
Abstract:
Objective To analyze the efficacy and safety of the three-in-one single-tablet regimen of bictegravir/emtricitabine/tenofovir alafenamide(BIC/FTC/TAF) in AIDS patients. Methods Newly treated patients who received a single tablet combination(BIC/FTC/...
2024, 45(4): 81-91.
doi: 10.12259/j.issn.2095-610X.S20240412
Abstract:
Objective To systematically evaluate the efficacy and safety of Jingangteng capsule combined with antibiotics in the treatment of chronic pelvic inflammatory disease. Methods Randomized controlled trials (RCTs) of Jingangteng capsule combined with a...
2024, 45(4): 92-98.
doi: 10.12259/j.issn.2095-610X.S20240413
Abstract:
Objective To evaluate the cost-effectiveness of nilotinib versus dasatinib in the second-line treatment of Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase. Methods Establish a Markov model for cost-effectiveness analysis, ...
2024, 45(4): 99-104.
doi: 10.12259/j.issn.2095-610X.S20240414
Abstract:
Objective To explore the clinical significance of coagulation function indexes in the diagnosis and treatment of elderly patients with novel coronavirus pneumonia. Methods This study retrospectively analyzed 68 elderly patients with novel coronaviru...
2024, 45(4): 105-112.
doi: 10.12259/j.issn.2095-610X.S20240415
Abstract:
Objective To investigate the effects of non-invasive ventilation in mean volumetric pressure support and automatic expiratory pressure (AVAPS-AE) mode on multichannel sleep monitoring (PSG) parameters, Epworth sleepiness Scale (ESS) score and comfort...
2024, 45(4): 113-119.
doi: 10.12259/j.issn.2095-610X.S20240416
Abstract:
Objective To explore the application of otoscopic and microscopic tympanoplasty in the treatment of chronic suppurative otitis media (CSOM) in young and middle-aged patients, and provide a reference for clinical treatment. Methods A total of 104 yo...
2024, 45(4): 120-127.
doi: 10.12259/j.issn.2095-610X.S20240417
Abstract:
Objective To explore the effect of precise liver pedicle dissection technique assisted laparoscopic hepatectomy on inflammatory immune stress and liver function. Methods A total of 114 patients with primary liver cancer in Dazhou Central Hospital fr...
2024, 45(4): 128-134.
doi: 10.12259/j.issn.2095-610X.S20240418
Abstract:
Objective To analyze the changes of immunoglobulin (Ig) during the process of transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) and predict the value of treatment efficacy. Methods A total of 100 HCC patients in Hebei...
2024, 45(4): 135-139.
doi: 10.12259/j.issn.2095-610X.S20240419
Abstract:
Objective To investigate the clinical efficacy of single-port and double port video-assisted thoracoscopic lobectomy in the treatment of lung cancer. Methods Patients who underwent thoracoscopic lobectomy in Beijing Armed Police Corps Hospital from ...
2024, 45(4): 140-145.
doi: 10.12259/j.issn.2095-610X.S20240420
Abstract:
Objective To investigate the correlation between the levels of intestinal flora, serum endotoxin (ET), and procalcitonin (PCT) in patients with sepsis and their disease severity and prognosis. Methods A total of 373 patients with sepsis in Jincheng ...
2024, 45(4): 146-151.
doi: 10.12259/j.issn.2095-610X.S20240421
Abstract:
Objective To study the efficacy and adverse reactions of vonoprazan fumarate tablets and esomeprazole magnesium enteric-coated tablets in the treatment of non-erosive reflux disease(NERD). Methods A total of 124 patients with NERD were selected and ...
2024, 45(4): 152-156.
doi: 10.12259/j.issn.2095-610X.S20240422
Abstract:
Objective To analyze the risk factors of persistent infection of high-risk human papillomavirus after radical hysterectomy for early cervical cancer. Methods A total of 159 early-stage cervical cancer patients who underwent radical hysterectomy or l...
2024, 45(4): 157-162.
doi: 10.12259/j.issn.2095-610X.S20240423
Abstract:
Objective To analyze the immunological indicators of TB patients co-infected with COVID-19, clarify their immune status, and explore the relationship and characteristics of relevant indicators with immune status. Methods The study group consisted of...
2024, 45(4): 163-169.
doi: 10.12259/j.issn.2095-610X.S20240424
Abstract:
Objective To investigate the clinical implications of lung function index, serum lactate dehydrogenase(LDH), cysteine protease inhibitor C(CysC) and platelet/white blood cell ratio(PWR) in patients with lung cancer. Methods From January 2023 to Jun...
2024, 45(4): 170-176.
doi: 10.12259/j.issn.2095-610X.S20240425
Abstract:
Objective To observe the levels of uric acid, Smad1 protein, and urine microalbumin in patients with type 2 diabetic nephropathy, and to analyze the correlation between these three factors and the effectiveness of dapagliflozin in treating type 2 dia...
2024, 45(4): 177-183.
doi: 10.12259/j.issn.2095-610X.S20240426
Abstract:
After lung cancer surgery, lung function impairment is an unavoidable issue in clinical practice, with factors such as surgical methods, resection sites, and individual differences leading to variations in the extent of lung function loss and recover...
After lung cancer surgery, lung function impairment is an unavoidable issue in clinical practice, with factors such as surgical methods, resection sites, and individual differences leading to variations in the extent of lung function loss and recover...
2024, 45(4): 184-191.
doi: 10.12259/j.issn.2095-610X.S20240427
Abstract:
Surgery is the main treatment for thyroid cancer, with features good postoperative prognosis, high survival rate, and long life expectancy. With the development of society and medical level, patients not only seek to cure the disease but also have hi...
Surgery is the main treatment for thyroid cancer, with features good postoperative prognosis, high survival rate, and long life expectancy. With the development of society and medical level, patients not only seek to cure the disease but also have hi...
2024, 45(4): 192-196.
doi: 10.12259/j.issn.2095-610X.S20240428
Abstract:
Objective To evaluate the effectiveness of the "WeChat + scenario simulation" interactive teaching mode in the practice of nutrition counseling and education, and to provide reference for the cultivation of undergraduate students' competence in the w...
2024, 45(4): 197-202.
doi: 10.12259/j.issn.2095-610X.S20240429
Abstract:
Objective To explore the improvement effect of Triangle hierarchical management+LEARNS model on blood sugar level, renal function level and psychological status of patients with diabetes nephropathy in nursing care. Methods A total of 74 diabetic ne...