2024 Vol. 45, No. 6
2024, 45(6): 1-6.
doi: 10.12259/j.issn.2095-610X.S20240601
Abstract:
Cirrhosis has a high global incidence rate and serious harm. Numerous studies have shown that liver cirrhosis may cause cardiovascular abnormalities in patients, which are closely related to the severity of the condition and may have adverse effects ...
Cirrhosis has a high global incidence rate and serious harm. Numerous studies have shown that liver cirrhosis may cause cardiovascular abnormalities in patients, which are closely related to the severity of the condition and may have adverse effects ...
2024, 45(6): 7-14.
doi: 10.12259/j.issn.2095-610X.S20240602
Abstract:
Objective To domesticate adherently cultured Vero cells into suspension-cultured cells and investigate their biological characteristics. Methods Cell culture was optimized using serum-free media and the "shaker adaptation method." Additionally, tumo...
2024, 45(6): 15-21.
doi: 10.12259/j.issn.2095-610X.S20240603
Abstract:
Objective To explore the effect of transient receptor potential channel 1 (TRPC1) protein and large conductivity Ca2+ activated K+ channel α subunit (BK-α) protein on diabetic nephropathy (DKD). Methods SD rats were randomly divided into a control g...
2024, 45(6): 22-35.
doi: 10.12259/j.issn.2095-610X.S20240604
Abstract:
Objective To explore the molecular mechanism of miR-205-5p targeting ERBB3 to regulate PI3K/AKT/mTOR pathway and inhibit angiogenesis in hemorrhoids. Methods The hemorrhoidal nucleus and normal perianal tissues of 12 patients from July 2021 to June 2...
2024, 45(6): 36-43.
doi: 10.12259/j.issn.2095-610X.S20240605
Abstract:
Objective To investigate the changes in liver autophagy factor activity in obese mice before and after sleeve gastrectomy(SG). Methods Male obese mice aged 6-8 weeks were randomly divided into a sham surgery group (Sham group, n=6) and a sleeve gast...
2024, 45(6): 44-50.
doi: 10.12259/j.issn.2095-610X.S20240606
Abstract:
Objective To investigate the potential causal relationship between oily nut consumption and primary lung cancer by two-sample Mendelian randomization method. Methods Single nucleotide polymorp hisms (P < 5×10-7) associated with oily nut intake we...
2024, 45(6): 51-56.
doi: 10.12259/j.issn.2095-610X.S20240607
Abstract:
Objective To study the chemical constituents of Brassica rapa L. and find its active components. Methods The chemical constituents of Brassica rapa L. were extracted by methanol reflux, separated and purified by silica gel column chromatography, thi...
2024, 45(6): 57-68.
doi: 10.12259/j.issn.2095-610X.S20240608
Abstract:
Objective To probe the expression level, prognostic value, and immune invasion of angipoietin-1 (ANGPT1)and its receptor tyrosine kinase (TEK)in pan-cancer. Methods TIMER2.0、Kaplan-Meier plotter and UALCAN etc. databases were used to analyze the exp...
2024, 45(6): 69-74.
doi: 10.12259/j.issn.2095-610X.S20240609
Abstract:
Objective To prepare aspirin enteric-coated tablets and investigate its in vitro - in vivo release characteristics. Methods The powder was directly pressed into tablets, and a coating solution with a solid content of 20% was prepared with the aqueou...
2024, 45(6): 75-84.
doi: 10.12259/j.issn.2095-610X.S20240610
Abstract:
Objective To discuss the difference in efficacy and safety of immune checkpoint inhibitor camrelizumab alone and combined chemotherapy in the treatment of non-small cell lung cancer. Aggregate analysis of multiple clinical trial data was conducted to...
2024, 45(6): 85-93.
doi: 10.12259/j.issn.2095-610X.S20240611
Abstract:
Objective To explore the association between lifestyle behaviors and depressive symptoms of middle school students in rural area of Miao nationality in Pingbian, Yunnan Province, and to provide a data reference for changing unhealthy lifestyle behavi...
2024, 45(6): 94-99.
doi: 10.12259/j.issn.2095-610X.S20240612
Abstract:
Objective To explore the influencing factors of cognitive impairment in elderly patients with depressive disorder. Methods 119 elderly patients with depression were recruited in the 1st Affiliated Hospital of Kunming Medical University. MoCA was use...
2024, 45(6): 100-105.
doi: 10.12259/j.issn.2095-610X.S20240613
Abstract:
Objective To investigate the hemodynamic changes after the occurrence of Stanford type A aortic dissection. Methods Computed tomography angiography(CTA) images of the aorta were collected from 4 Stanford A type aortic dissection patients and 2 healt...
2024, 45(6): 106-112.
doi: 10.12259/j.issn.2095-610X.S20240614
Abstract:
Objective To investigate the characteristics of parathyroid hormone (PTH) and estrogen receptor (ER) gene polymorphisms in patients with type 2 diabetes mellitus (T2DM) complicated with osteoporosis (OP). Methods 110 patients with T2DM from Kunming ...
2024, 45(6): 113-119.
doi: 10.12259/j.issn.2095-610X.S20240615
Abstract:
Objective To explore the clinical efficacy of acetylcysteine solution retained perfusion inhalation treatment under electronic bronchoscopy in children with severe bacterial pneumonia. Methods From January 1, 2021 to December 31, 2022, 86 children w...
2024, 45(6): 120-125.
doi: 10.12259/j.issn.2095-610X.S20240616
Abstract:
Objective To investigate the value of vectorcardiography in the diagnosis of abnormal cardiac electrical activity in hypertension, and to analyze the influencing factors of early cardiac target organ damage. Methods 80 cases in the Department of Car...
2024, 45(6): 126-131.
doi: 10.12259/j.issn.2095-610X.S20240617
Abstract:
Objective To investigate the application value of transvaginal three-dimensional ultrasound in the determination of endometrial receptivity. Methods A retrospective study was conducted on 106 patients who were scheduled to undergo assisted reproduct...
2024, 45(6): 132-139.
doi: 10.12259/j.issn.2095-610X.S20240618
Abstract:
Objective To investigate the nutritional status and its influencing factors among the elderly in some communities of Kunming, in order to provide more targeted suggestions for preventing malnutrition among the elderly in the above communities, thereb...
2024, 45(6): 140-144.
doi: 10.12259/j.issn.2095-610X.S20240619
Abstract:
Objective To investigate the therapeutic efficacy and safety of the combination of monosialotetrahexosylganglioside (GM1) injection and Batroxobin in treating sudden deafness. Methods The clinical data of 162 patients with sudden deafness in Affilia...
2024, 45(6): 145-153.
doi: 10.12259/j.issn.2095-610X.S20240620
Abstract:
Objective To establish the derived indicators from blood cell analysis of the elderly in Anning region of Yunnan province, lymphocyte to monocyte ratio (LMR), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) reference interval...
2024, 45(6): 154-160.
doi: 10.12259/j.issn.2095-610X.S20240621
Abstract:
Objective To investigate the effectiveness and safety of cyclophenol combined with remifentanil in anesthesia for laparoscopic radical gastrectomy for gastric cancer. Methods A total of 100 patients who underwent laparoscopic radical gastrectomy for...
2024, 45(6): 161-165.
doi: 10.12259/j.issn.2095-610X.S20240622
Abstract:
Circular RNA (circRNA), formed by reverse splicing of pre-mRNA, constitutes a closed-loop RNA structure with diversity in molecular characteristics, biological functions, and regulatory mechanisms. In recent years, there has been growing recognition ...
Circular RNA (circRNA), formed by reverse splicing of pre-mRNA, constitutes a closed-loop RNA structure with diversity in molecular characteristics, biological functions, and regulatory mechanisms. In recent years, there has been growing recognition ...
2024, 45(6): 166-170.
doi: 10.12259/j.issn.2095-610X.S20240623
Abstract:
The current situation of anesthesia nursing unit construction is described, along with the theoretical basis and methodology for the construction of its nursing-sensitive quality indicators. A review is presented on the construction and application o...
The current situation of anesthesia nursing unit construction is described, along with the theoretical basis and methodology for the construction of its nursing-sensitive quality indicators. A review is presented on the construction and application o...
2024, 45(6): 171-174.
doi: 10.12259/j.issn.2095-610X.S20240624
Abstract:
Objective To compare the differences in the competency of the students in the standardized training of residents with different learning styles, and explore more effective clinical teaching strategies. Methods Kolb learning style and clinician post ...
2024, 45(6): 175-181.
doi: 10.12259/j.issn.2095-610X.S20240625
Abstract:
Objective To explore the relationship and influence path between nurses’ perceived work environment, hospital safety climate and nurses’ satisfaction. Methods Using convenience sampling method, 444 in-service nurses in a third-class A hospital in Ch...
2024, 45(6): 182-189.
doi: 10.12259/j.issn.2095-610X.S20240626
Abstract:
Objective To investigate the current status of psychological resilience of clinical nurses in a cancer hospital, identify the potential profile categories of psychological resilience of nurses, and explore its subgroup characteristics and influencing...
2024, 45(6): 190-196.
doi: 10.12259/j.issn.2095-610X.S20240627
Abstract:
Objective To analyze the application effect of active circulatory breathing training in patients undergoing thoracoscopic lung cancer surgery based on 5A (Ask, Asses, Advice, Assist, Arrange) mode. Methods 100 patients with lung cancer, treated by t...