Value of Intravenous Contrast-enhanced Ultrasound in Differential Diagnosis of Adenomyosis and Uterine Fibroids

Ju-xiang MA; Yong-hong MA; Shan-shan GAO; Jue WU; Min ZHU; Zhen-ling DUAN

doi:10.12259/j.issn.2095-610X.S20201109

Volume 41 Issue 11

Dec. 2020

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Article Navigation > Journal of Kunming Medical University > 2020 > 41(11): 114-118

Ju-xiang MA, Yong-hong MA, Shan-shan GAO, Jue WU, Min ZHU, Zhen-ling DUAN. Value of Intravenous Contrast-enhanced Ultrasound in Differential Diagnosis of Adenomyosis and Uterine Fibroids[J]. Journal of Kunming Medical University, 2020, 41(11): 114-118. doi: 10.12259/j.issn.2095-610X.S20201109

Citation:

Ju-xiang MA, Yong-hong MA, Shan-shan GAO, Jue WU, Min ZHU, Zhen-ling DUAN. Value of Intravenous Contrast-enhanced Ultrasound in Differential Diagnosis of Adenomyosis and Uterine Fibroids[J]. Journal of Kunming Medical University, 2020, 41(11): 114-118. doi: 10.12259/j.issn.2095-610X.S20201109

Citation:

Ju-xiang MA, Yong-hong MA, Shan-shan GAO, Jue WU, Min ZHU, Zhen-ling DUAN. Value of Intravenous Contrast-enhanced Ultrasound in Differential Diagnosis of Adenomyosis and Uterine Fibroids[J]. Journal of Kunming Medical University, 2020, 41(11): 114-118. doi: 10.12259/j.issn.2095-610X.S20201109

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Value of Intravenous Contrast-enhanced Ultrasound in Differential Diagnosis of Adenomyosis and Uterine Fibroids

doi: 10.12259/j.issn.2095-610X.S20201109

Dept. of Obstetrics and Gynecology，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

Received Date: 2020-09-03
Available Online: 2020-12-03
Publish Date: 2020-11-25

Abstract

Abstract

Objective To evaluate the differential diagnosis of uterine adenomyosis and uterine fibroids by intravenous contrast-enhanced ultrasound（CEUS）. Methods Routine ultrasonography and intravenous CEUS were performed in patients with uterine fibroids and adenomyosis in the department of obstetrics and gynecology, the First Affiliated Hospital of Kunming Medical University from December 2017 to December 2019. The results of postoperative pathological examination were compared, the accuracy of conventional ultrasound and intravenous CEUS was analyzed, and the characteristics of CEUS for uterine fibroids and adenomyosis were also analyzed. Results 1. The accuracy rates of conventional ultrasound and CEUS in the diagnosis of uterine fibroids were 92% and 98%, respectively, with statistically significant differences（P < 0.05）. The accuracy of adenomyosis diagnosis was 91% and 100%, respectively, with statistically significant difference（P < 0.05）. 2. According to intravenous contrast-enhanced ultrasonography, the onset time of adenomyosis was earlier than that of adenomyoma, and the peak time was earlier than that of uterine fibroids, and the peak intensity was lower than that of uterine fibroids, with statistically significant difference（P < 0.05）. Conclusions 1. Intravenous CEUS is superior to conventional ultrasonography in the diagnosis of adenomyosis and uterine fibroids. 2. Adenomyosis and hysteromyoma have different characteristic changes in contrast-enhanced ultrasonography, which can be used as the key point to differentiate them.
- Contrast-enhanced ultrasound,
- Adenomyosis,
- Uterine fibroids

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References(18)

References

[1]	Stewart E A,Cookson C L,Gandolfo R A,et al. Epidemiology of uterine fibroids:a systematic review[J]. BJOG.,2017,124(10):1501-1512. doi: 10.1111/1471-0528.14640
[2]	Miettinen M,Fetsch J F. Evaluation of biological potential of smooth muscle tumours[J]. Histopathology,2006,48(1):97-105. doi: 10.1111/j.1365-2559.2005.02292.x
[3]	Spies James B. Current role of uterine artery embolization in the management of uterine fibroids[J]. Clin Obstet Gynecol.,2016,59(1):93-102. doi: 10.1097/GRF.0000000000000162
[4]	谢幸, 苟文丽, 林仲秋, 等, 妇产科学[M]. 第8版. 北京: 人民卫生出版社, 2013: 310-313.
[5]	郭静. 常规超声与超声造影对子宫肌瘤诊断价值分析[J].临床医药文献电子杂志,2016,3(3):579-582.
[6]	Hirotaka Ota,Toshinobu Tanaka. Stromal vascularization in the endometrium during adenomyosis[J]. Microscopy Research and Technique,2003,60(4):445-449. doi: 10.1002/jemt.10282
[7]	江峰,胡竞,吴娇娇. 子宫腺肌症的超声造影和时间-强度曲线特征[J].中国医学影像技术,2016,32(5):761-764.
[8]	施红, 蒋天安. 实用超声造影诊断学[M]. 北京: 人民军医出版社 2013: 436-437.
[9]	Antonia Carla Testa,Gabriella Ferrandina,Erika Fruscella,et al. The use of contrasted transvaginal sonography in the diagnosis of gynecologic diseases:a preliminary study[J]. Ultrasound Med.,2005,24(9):1267-1278. doi: 10.7863/jum.2005.24.9.1267
[10]	Mojisla B. Imaging diagnosis of adenomyosis[J]. Gynaecological and Perinatal Practice,2006,6(1-2):63-69. doi: 10.1016/j.rigp.2005.09.004
[11]	程万枝,明丽. 超声造影在宫体占位性病变中的探讨[J].影像研究与医学应用,2016,32(16):2692-2694.
[12]	陈伟芳,张江宇,王意. 子宫肉瘤34例临床特征分析[J].实用医学杂志,2016,32(16):2692-2694. doi: 10.3969/j.issn.1006-5725.2016.16.028
[13]	Rami Aviram,Yifat Ochshorn,Ofer Markovitch,et al. Uterine sarcomas versus leiomyomas:Gray-scale and Doppler sonographic findings[J]. J Clin Ultrasound,2005,33(1):10-13. doi: 10.1002/jcu.20075
[14]	Yan Zhang,Meiwu Zhang,Xiaoxiang Fan,et al. Contrast-enhanced ultrasound is better than magnetic resonance imaging in evaluating the short-term results of microwave ablation treatment of uterine fibroids[J]. Exp Ther Med,2017,14(5):5103-5108.
[15]	Marret H,Tranquart F,Sauget S,et al. Contrast-enhanced sonography during uterine artery embolization for the treatment of leiomyomas[J]. Ultrasound Obstet Gynecol,2004,23(1):77-79. doi: 10.1002/uog.944
[16]	刘洋,房秀霞. 超声造影在妇产科疾病中的应用及进展[J].世界最新医学信息文摘,2018,18(A2):128-129.
[17]	郑荣琴. 妇科超声造影临床应用指南[J].中华医学超声杂志(电子版),2015,12(2):94-98.
[18]	姚瑞红,赵卫,姜永能. 六氟化硫微泡在HlFU治疗T2Wl高信号子宫肌瘤中的临床应用[J].昆明医科大学学报,2016,37(11):76-81. doi: 10.3969/j.issn.1003-4706.2016.11.017

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