Clinical Effect of Dexmedetomidine on Shivering Reaction in Cesarean Section Patients during Combined Spinal-epidural Anesthesia

Mai-qiao YANG; Fu-rong ZHANG; Li-li LIU; Xiao-ying LIU; ping LIU

doi:10.12259/j.issn.2095-610X.S20201125

Volume 41 Issue 11

Dec. 2020

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Article Navigation > Journal of Kunming Medical University > 2020 > 41(11): 98-102

Mai-qiao YANG, Fu-rong ZHANG, Li-li LIU, Xiao-ying LIU, ping LIU. Clinical Effect of Dexmedetomidine on Shivering Reaction in Cesarean Section Patients during Combined Spinal-epidural Anesthesia[J]. Journal of Kunming Medical University, 2020, 41(11): 98-102. doi: 10.12259/j.issn.2095-610X.S20201125

Citation:

Mai-qiao YANG, Fu-rong ZHANG, Li-li LIU, Xiao-ying LIU, ping LIU. Clinical Effect of Dexmedetomidine on Shivering Reaction in Cesarean Section Patients during Combined Spinal-epidural Anesthesia[J]. Journal of Kunming Medical University, 2020, 41(11): 98-102. doi: 10.12259/j.issn.2095-610X.S20201125

Citation:

Mai-qiao YANG, Fu-rong ZHANG, Li-li LIU, Xiao-ying LIU, ping LIU. Clinical Effect of Dexmedetomidine on Shivering Reaction in Cesarean Section Patients during Combined Spinal-epidural Anesthesia[J]. Journal of Kunming Medical University, 2020, 41(11): 98-102. doi: 10.12259/j.issn.2095-610X.S20201125

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Clinical Effect of Dexmedetomidine on Shivering Reaction in Cesarean Section Patients during Combined Spinal-epidural Anesthesia

doi: 10.12259/j.issn.2095-610X.S20201125

1.
Dept. of Anesthesia，Yan'an Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650051
2.
Dept. of Anesthesiology，Kunming Medical University，Kunming Yunnan 650500，China

Received Date: 2020-10-12
Available Online: 2020-12-03
Publish Date: 2020-11-25

Abstract

Abstract

Objective To study the preventive and therapeutic effect of dexmedetomidine hydrochloride on shivering reaction of caesarean section patients during combined spinal-epidural anesthesia. Methods Sixty patients undergoing caesarean section under combined spinal-epidural anesthesia in Yan'an Hospital affiliated to Kunming Medical University from September to December in 2019 were randomly divided into experimental group and control group.0.5 μg/kg. Dexmedetomidine hydrochloride was pumped within 10 minutes immediately after the umbilical cord was cut off in the experimental group. The control group was given the same dose of saline. The ECG, BP, HR, SpO₂, RR, sedation（according to Ramsay sedation score）, shivering reaction（according to Wrench grade）and nausea and vomiting were observed continuously before anesthesia（T₀）, 5 minutes after anesthesia（T₁）, at the time of fetal delivery（T₂）, 10 minutes after fetal delivery（T₃）, at the end of operation（T₄）. Results The level of shivering reaction in the experimental group was lower than that in the control group（P < 0.05）. There was no significant difference in BP, HR, SpO₂ between the two groups at corresponding time points（P > 0.05）. Ramsay sedation score at T₃ and T₄ was significantly higher than that at T₀ in the experimental group（P < 0.05）, and significantly higher than that in the control group（P < 0.05）. Conclusion The application of dexmedetomidine during combined spinal-epidural anesthesia in cesarean section can effectively prevent and treat shivering reaction.
- Dexmedetomidine,
- Combined spinal-epidural anesthesia,
- Shivering reaction,
- Cesarean delivery

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References(14)

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