Clinical Observation on Impacts of Ureaplasma Urealytieum Infection upon Quality of Sperm

He-yun ZHANG; Wei-hui LU; Yun ZHAO; Ying ZHENG; Rui GONG; Jian LI; Cui-hua WANG; Yang WANG; Wan-ting CHEN; Yuan-yuan OU; Hui GAO

doi:10.12259/j.issn.2095-610X.S20201127

Volume 41 Issue 11

Dec. 2020

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Article Navigation > Journal of Kunming Medical University > 2020 > 41(11): 134-137

He-yun ZHANG, Wei-hui LU, Yun ZHAO, Ying ZHENG, Rui GONG, Jian LI, Cui-hua WANG, Yang WANG, Wan-ting CHEN, Yuan-yuan OU, Hui GAO. Clinical Observation on Impacts of Ureaplasma Urealytieum Infection upon Quality of Sperm[J]. Journal of Kunming Medical University, 2020, 41(11): 134-137. doi: 10.12259/j.issn.2095-610X.S20201127

Citation:

He-yun ZHANG, Wei-hui LU, Yun ZHAO, Ying ZHENG, Rui GONG, Jian LI, Cui-hua WANG, Yang WANG, Wan-ting CHEN, Yuan-yuan OU, Hui GAO. Clinical Observation on Impacts of Ureaplasma Urealytieum Infection upon Quality of Sperm[J]. Journal of Kunming Medical University, 2020, 41(11): 134-137. doi: 10.12259/j.issn.2095-610X.S20201127

Citation:

He-yun ZHANG, Wei-hui LU, Yun ZHAO, Ying ZHENG, Rui GONG, Jian LI, Cui-hua WANG, Yang WANG, Wan-ting CHEN, Yuan-yuan OU, Hui GAO. Clinical Observation on Impacts of Ureaplasma Urealytieum Infection upon Quality of Sperm[J]. Journal of Kunming Medical University, 2020, 41(11): 134-137. doi: 10.12259/j.issn.2095-610X.S20201127

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Clinical Observation on Impacts of Ureaplasma Urealytieum Infection upon Quality of Sperm

doi: 10.12259/j.issn.2095-610X.S20201127

1.
Dept. of Urology
2.
Dept. of Laboratory，Yan’an Hospital，Kunming Medical University，Kunming Yunnan 650051，China

Received Date: 2020-08-11
Available Online: 2020-12-03
Publish Date: 2020-11-25

Abstract

Abstract

Objectives To explore the relationship between sperm abnormality and genital ureaplasma urealytieum（UU） infection, and discuss how do they interact with each other. Methods Three hundreds and forty-seven patients with male infertility were divided into UU-positive and UU-negative groups based on if they suffered UU infection. Subsequently, two groups were observed in terms of quality of sperm（including sperm count, sperm density, sperm mobility and proportion of forward motile sperm）, liquefaction time and rate of sperm abnormalities. After the UU-positive group was treated with azithromycin and became UU-negative, sperm was recollected from them for analysis. Results Before the UU-positive group was treated, all of its sperm indicators were lower than the UU-negative group（P < 0.01）. After they were treated and became negative, the sperm count, sperm density, mobility, proportion of Grade A sperm and ratio of Grade A+B sperm increased by 20.59%, 16.44%, 19.56%, 24.89% and 32.69% respectively, while the sperm deformity rate declined by 1.39%. In particular, the liquefaction rate increased from 20.11% before treatment to 92.53% after the group was treated and became UU-negative. The effects of treatment were evident, and differences were statistically significant before and after treatment（P < 0.01）. Compared with the UU-negative group, the differences were not statistically significant（P > 0.05）. Conclusions Male genital ureaplasma urealytieum infection may weaken sperm quality, particularly prolong liquefaction time of sperm and increase male infertility, Once UU infection is detected, prompt treatment is needed, so as to reduce male infertility.
- Ureaplasma urealytieum,
- Sperm abnormality,
- Sperm nonliquefaction,
- Male infertility

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References(13)

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