Volume 41 Issue 11
Dec.  2020
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Xiao-zhi XU, Jing-hui YANG. Comparison of Exchange Transfusion and Intensive Phototherapy in the Treatment of Neonatal Hyperbilirubinemia[J]. Journal of Kunming Medical University, 2020, 41(11): 44-48. doi: 10.12259/j.issn.2095-610X.S20201131
Citation: Xiao-zhi XU, Jing-hui YANG. Comparison of Exchange Transfusion and Intensive Phototherapy in the Treatment of Neonatal Hyperbilirubinemia[J]. Journal of Kunming Medical University, 2020, 41(11): 44-48. doi: 10.12259/j.issn.2095-610X.S20201131

Comparison of Exchange Transfusion and Intensive Phototherapy in the Treatment of Neonatal Hyperbilirubinemia

doi: 10.12259/j.issn.2095-610X.S20201131
  • Received Date: 2020-09-16
  • Publish Date: 2020-11-25
  •   Objective   To explore the difference in the incidence of complications and hospitalization time between exchange transfusion combined with intensive phototherapy and single intensive phototherapy in the treatment of neonatal hyperbilirubinemia.   Methods   We retrospectively analyzed the data of 121 hyperbilirubinemia in term infants. We compared the difference in the incidence of complications and the hospitalization time between the exchange transfusion combined with intensive phototherapy and single intensive phototherapy in the treatment of neonatal hyperbilirubinemia. We also studied the incidences of anemia when we use different volume ratios of red blood cells and plasma.   Results   There were more complications in the group of exchange transfusion combined with intensive phototherapy than the intensive phototherapy group, otherwise there was no difference in the hospitalization time between the two groups. The incidence of anemia of the 1:1 exchange transfusion group was higher than that of the 2:1 exchange group.   Conclusions   All neonates with hyperbilirubinemia should be considered phototherapy for 4 hours or 6 hours and reassess whether they need exchange transfusion therapy to reduce the incidence of complications. If the exchange transfusion therapy is used, it is suggested that the volume ratios of red blood cells to plasma is 2:1 rather than 1:1.
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