A Comparative Study of the Cognitive Function in Patients with Different Degrees of Depression

Xian LI; Chang-liang JI; Shu-e ZENG; Shu-yun YANG; Hao-qi YANG; Ya-ting HOU

doi:10.12259/j.issn.2095-610X.S20201226

Volume 41 Issue 12

Dec. 2019

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Article Navigation > Journal of Kunming Medical University > 2020 > 41(12): 94-98

Xian LI, Chang-liang JI, Shu-e ZENG, Shu-yun YANG, Hao-qi YANG, Ya-ting HOU. A Comparative Study of the Cognitive Function in Patients with Different Degrees of Depression[J]. Journal of Kunming Medical University, 2020, 41(12): 94-98. doi: 10.12259/j.issn.2095-610X.S20201226

Citation:

Xian LI, Chang-liang JI, Shu-e ZENG, Shu-yun YANG, Hao-qi YANG, Ya-ting HOU. A Comparative Study of the Cognitive Function in Patients with Different Degrees of Depression[J]. Journal of Kunming Medical University, 2020, 41(12): 94-98. doi: 10.12259/j.issn.2095-610X.S20201226

Citation:

Xian LI, Chang-liang JI, Shu-e ZENG, Shu-yun YANG, Hao-qi YANG, Ya-ting HOU. A Comparative Study of the Cognitive Function in Patients with Different Degrees of Depression[J]. Journal of Kunming Medical University, 2020, 41(12): 94-98. doi: 10.12259/j.issn.2095-610X.S20201226

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A Comparative Study of the Cognitive Function in Patients with Different Degrees of Depression

doi: 10.12259/j.issn.2095-610X.S20201226

Dept. of Sleep Medicine Centre，Psychiatric Hospital of Yunnan Province，Kunming Yunnan 650224，China

Received Date: 2020-05-07
Publish Date: 2019-12-26

Abstract

Abstract

Objective Based on the fact that Yunnan is a remote and bordering area with multiple ethnic minorities, Wechsler intelligence Scale and Raven standard Reasoning test were used to compare the difference of cognitive function in patients with different degrees of depression. Methods The cognitive function of 100 ICD-10 patients with depression （at admission and 6 weeks after admission） and 100 healthy individuals admitted to Yunnan Psychiatric Hospital from August 2019 to December 2019 were assessed using Raven Standard Reasoning Test and Wechsler Adult Intelligence Scale. Seventeen items of the Hamilton Depression Scale were used to assess the severity of depression （at the time of admission and 6 weeks after admission）, and the patients were divided into 3 groups: severe, modest and mild groups. The data were analyzed by SPSS17.0 statistical software package. Results （1） In normal group, there was no significant difference between RIQ and FIQ （P > 0.05）. In the depression group, FIQ was significantly higher than RIQ both at admission and 6 weeks after admission of antidepressant treatment （ P < 0.05）. （2） The results of RIQ, VIQ, PIQ and FIQ at 6 weeks of admission between control group, depression group and the normal control group were as follows: The depression group had the lowest score at admission, followed by the 6-weeks after treatment, and the normal control group had the highest score （ P < 0.05）. （3） The comparison results of RIQ, VIQ, PIQ and FIQ between the depression group admitted to hospital and the depression group at 6 weeks were: severe depression was the lowest, followed by moderate depression, and mild depression was the highest （ P < 0.05）. Conclusion （1） There was no significant difference between Wechsler's IQ and Raven's IQ in the normal group; however, in the depression group, Wechsler's IQ was significantly higher than Ravin's IQ, and Ravin's IQ was related to performance IQ, so the impairment of performance IQ was more obvious in depression patients. （2） The cognitive function of patients with depression was impaired. After antidepressant treatment, the cognitive function was improved, but still could not reach the normal level. （3） As the degree of depression increases, the severity of cognitive impairment also increase, both at the time of admission and six weeks after treatment,
- Depression,
- Raven's standard progressive matrices, SPM,
- Wechsler adult intelligence scale,
- Cognitive impairment

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References(12)

References

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