Efficacy of Deside Cream Combined with Compound Polymyxin B Ointment in the Treatment of Moderate-severe Atopic Dermatitis in Children

Xin-yue CHEN; Zong-han CHEN; Wei-jia ZHAO

doi:10.12259/j.issn.2095-610X.S20201228

Volume 41 Issue 12

Dec. 2019

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Article Navigation > Journal of Kunming Medical University > 2020 > 41(12): 104-107

Xin-yue CHEN, Zong-han CHEN, Wei-jia ZHAO. Efficacy of Deside Cream Combined with Compound Polymyxin B Ointment in the Treatment of Moderate-severe Atopic Dermatitis in Children[J]. Journal of Kunming Medical University, 2020, 41(12): 104-107. doi: 10.12259/j.issn.2095-610X.S20201228

Citation:

Xin-yue CHEN, Zong-han CHEN, Wei-jia ZHAO. Efficacy of Deside Cream Combined with Compound Polymyxin B Ointment in the Treatment of Moderate-severe Atopic Dermatitis in Children[J]. Journal of Kunming Medical University, 2020, 41(12): 104-107. doi: 10.12259/j.issn.2095-610X.S20201228

Citation:

Xin-yue CHEN, Zong-han CHEN, Wei-jia ZHAO. Efficacy of Deside Cream Combined with Compound Polymyxin B Ointment in the Treatment of Moderate-severe Atopic Dermatitis in Children[J]. Journal of Kunming Medical University, 2020, 41(12): 104-107. doi: 10.12259/j.issn.2095-610X.S20201228

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Efficacy of Deside Cream Combined with Compound Polymyxin B Ointment in the Treatment of Moderate-severe Atopic Dermatitis in Children

doi: 10.12259/j.issn.2095-610X.S20201228

1.
Dept. of Dermatology，Kunming Children’s Hospital，Kunming Yunnan 650228
2.
Higher Education Research and Evaluation Center，Yunnan University of Traditional ChineseMedicine，Kunming Yunnan 650500
3.
Dept. of Dermatology，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

Received Date: 2020-07-01
Publish Date: 2019-12-26

Abstract

Abstract

Objective To analyze the efficacy of deside cream combined with compound polymyxin B ointment in the treatment of moderate-severe atopic dermatitis in children. Methods A total of 82 children with severe atopic dermatitis in the dermatology department of Kunming Children's Hospital from January 2019 to March 2020 were selected and divided into control group（41 cases）and experimental group（41 cases）randomly. Deside cream was administered in control group, while deside combined with compound polymyxin B ointment were administer in experimental group. The disappearance time of dry skin, itching, eczema like rash, EASI level, eosinophil level, total effective rate and adverse reactions of children before and after treatment were compared between the two groups. Results The disappearance time of dry skin, itching and eczema-like rash in the experimental group was shorter than that in the control group（P < 0.05）. After treatment, EASI level and eosinophil level were lower than those of the control group（ P < 0.05）. The total effective rate of the experimental group was higher than that of the control group（ P < 0.05）. There was no difference in adverse reactions between the two groups（ P > 0.05）. Conclusion Deside cream combined with compound polymyxin B ointment is effective in treating moderate-severe atopic dermatitis in children. It can accelerate the disappearance of symptoms, improve skin lesions and hematological indicators, with fewer adverse reactions and high safety.
- Denide cream,
- Compound polymyxin B ointment,
- Moderate-severe atopic dermatitis in children,
- Curative effect

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References(17)

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