Clinical Analysis of 46 Children with Necrotizing Pneumonia

Song-tao BIN; Ming LI; Li TAN; Cheng-qing WU; Ji WANG; Xiao-qin HU

doi:10.12259/j.issn.2095-610X.S20210102

Volume 42 Issue 1

Jan. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(1): 124-129

Song-tao BIN, Ming LI, Li TAN, Cheng-qing WU, Ji WANG, Xiao-qin HU. Clinical Analysis of 46 Children with Necrotizing Pneumonia[J]. Journal of Kunming Medical University, 2021, 42(1): 124-129. doi: 10.12259/j.issn.2095-610X.S20210102

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Song-tao BIN, Ming LI, Li TAN, Cheng-qing WU, Ji WANG, Xiao-qin HU. Clinical Analysis of 46 Children with Necrotizing Pneumonia[J]. Journal of Kunming Medical University, 2021, 42(1): 124-129. doi: 10.12259/j.issn.2095-610X.S20210102

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Clinical Analysis of 46 Children with Necrotizing Pneumonia

doi: 10.12259/j.issn.2095-610X.S20210102

Dept. of Respiratory Medicine, Kunming Children’s Hospital，Kunming Yunnan 650031，China

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Corresponding author: 胡晓琴，E-mail：huxiaoqin@etyy.cn
Received Date: 2020-08-11
Publish Date: 2021-01-25

Abstract

Abstract

Objective To study the clinical characteristics, treatment and prognosis of necrotizing pneumonia (NP) in children. Method The clinical data of 46 patients with NP admitted to the Department of Respiratory Medicine of Kunming Children's Hospital from April 2017 to April 2020 were collected retrospectively. According to the etiological score, the patients were divided into mycoplasma pneumoniae necrotizing pneumonia (MPNP) group and bacterial necrotizing pneumonia (BNP) group. The clinical manifestations, laboratory examination results, imaging features, bronchoscopic manifestations, treatment process and prognosis of the two groups were compared later. Methods Of the 46 NP cases, 30 were MPNP and 16 were BMP. The age of children in MPNP group was significantly higher than that in BNP group. There was no significant difference between the total fever days in MPNP group and the total fever days in BNP group. The proportion of patients with shortness of breath and in need of oxygen therapy was significantly higher in BNP group than that in MPNP group. There was no significant difference between the two groups in the proportion of respiratory failure requiring mechanical ventilation. Laboratory tests showed that BNP had the higher white blood cell count and PCT c-reactive protein (CRP) than MPNP children. Imaging examination showed that the necrotic lesion in MPNP group was significantly later than that in BNP group. There was no significant difference in the proportion of pleural effusion between the two combinations. Electronic bronchoscopy revealed that there were a variety of inflammatory changes in the characteristics of tracheal and bronchial mucosa, bronchial lumen and secretions of MPNP children. The bronchial mucosa, lumen and secretions of BNP were mainly suppurative. After the effective treatment, the two groups of patients improved and were discharged from the hospital without any death. There was no significant difference in length of stay between the two groups. There was no significant difference in the absorption time between the two groups. Conclusion Patients with NP have the long fever, long hospital stay, long imaging absorption, and severe and diverse bronchoscopy. Fever and cough for more than 10 days, pleural effusion, CRP for more than 80 mg/L, and ricin-like alveolar lavage fluid may be the risk factors for NP development. NP has a good prognosis after the active and effective treatment.
- Children,
- Mycoplasma pneumoniae,
- Necrotic pneumonia,
- Bacteria

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