Volume 42 Issue 1
Jan.  2021
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Article Navigation >  Journal of Kunming Medical University  > 2021  >  42(1): 157-160
Xiao-yun WANG, Qiao-yun WANG, Ming-hua GU, Yu DING, Yu-wen GUANG, Ji-lan ZHANG. Mechanism of miR-373 on Behaviors of Depression-mice via P2X7R[J]. Journal of Kunming Medical University, 2021, 42(10): 29-37. doi: 10.12259/j.issn.2095-610X.S20211030
Citation: Li DENG, Hong-li FANG, Guang-qiong CAO, Hui-fang GAO. Research on the Relationship between Serum Homocysteine Level and Blood Lipids in Healthy People[J]. Journal of Kunming Medical University, 2021, 42(1): 157-160. doi: 10.12259/j.issn.2095-610X.S20210107
shu

Research on the Relationship between Serum Homocysteine Level and Blood Lipids in Healthy People

doi: 10.12259/j.issn.2095-610X.S20210107

  • Dept. of Health Management Center，The First Affiliated Hospital of Kumming Medical University，Kunming Yunnan 650032，China

  • Received Date: 2020-08-12
    Available Online: 2021-01-26
  • Publish Date: 2021-01-26
    Abstract
  •   Objective  To explore the relationship between serum homocysteine（Hcy）and blood lipid in physical examination population and provide the evidence for the mechanism research between Hcy and lipid level.  Methods  234 health examinees who came to the health management center of a grade A hospital in Yunnan Province from January 2019 to November 2019 were randomly selected as the subjects. General information, smoking, drinking and diabetes histories of the cases were collected. Plasma homocysteine, blood lipid were measured. Statistical analysis software SPSS 17.0 was used to analyze the level of Hcy and its influencing factors on blood lipid.  Results  （1）The value of Hcy Md（QR）for males was 12.36（9.90）μmol/L, for females was 7.73（6.40）μmol/L. There was a significant difference between males and females.（2）Smoking history（KW = 15.335, P < 0.001）, drinking history（KW = 18.937, P < 0.001）, LDL-C（r = 0.304, P = 0.002）、TC（r = 0.294, P = 0.003）were all correlated with blood Hcy level.  Conclusion  Total serum cholesterol（TC）, low density lipoprotein（LDL-C）are all correlated with blood Hcy level. And smoking, drinking and men are also related to the increase of Hcy level. It is necessary to strengthen the monitoring of the level of Hcy in the risky population and do more research about the relationship between Hcy and blood lipid.
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