Research on the Relationship between Serum Homocysteine Level and Blood Lipids in Healthy People

Li DENG; Hong-li FANG; Guang-qiong CAO; Hui-fang GAO

doi:10.12259/j.issn.2095-610X.S20210107

Volume 42 Issue 1

Jan. 2021

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Li DENG, Hong-li FANG, Guang-qiong CAO, Hui-fang GAO. Research on the Relationship between Serum Homocysteine Level and Blood Lipids in Healthy People[J]. Journal of Kunming Medical University, 2021, 42(1): 157-160. doi: 10.12259/j.issn.2095-610X.S20210107

Citation:

Li DENG, Hong-li FANG, Guang-qiong CAO, Hui-fang GAO. Research on the Relationship between Serum Homocysteine Level and Blood Lipids in Healthy People[J]. Journal of Kunming Medical University, 2021, 42(1): 157-160. doi: 10.12259/j.issn.2095-610X.S20210107

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Research on the Relationship between Serum Homocysteine Level and Blood Lipids in Healthy People

doi: 10.12259/j.issn.2095-610X.S20210107

Dept. of Health Management Center，The First Affiliated Hospital of Kumming Medical University，Kunming Yunnan 650032，China

Received Date: 2020-08-12
Available Online: 2021-01-26
Publish Date: 2021-01-26

Abstract

Abstract

Objective To explore the relationship between serum homocysteine（Hcy）and blood lipid in physical examination population and provide the evidence for the mechanism research between Hcy and lipid level. Methods 234 health examinees who came to the health management center of a grade A hospital in Yunnan Province from January 2019 to November 2019 were randomly selected as the subjects. General information, smoking, drinking and diabetes histories of the cases were collected. Plasma homocysteine, blood lipid were measured. Statistical analysis software SPSS 17.0 was used to analyze the level of Hcy and its influencing factors on blood lipid. Results （1）The value of Hcy Md（QR）for males was 12.36（9.90）μmol/L, for females was 7.73（6.40）μmol/L. There was a significant difference between males and females.（2）Smoking history（KW = 15.335, P < 0.001）, drinking history（KW = 18.937, P < 0.001）, LDL-C（r = 0.304, P = 0.002）、TC（r = 0.294, P = 0.003）were all correlated with blood Hcy level. Conclusion Total serum cholesterol（TC）, low density lipoprotein（LDL-C）are all correlated with blood Hcy level. And smoking, drinking and men are also related to the increase of Hcy level. It is necessary to strengthen the monitoring of the level of Hcy in the risky population and do more research about the relationship between Hcy and blood lipid.
- Homocysteine,
- Blood lipid,
- Correlation research

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References(18)

References

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