Research Progress of miRNA-145 in Malignant Tumors of Digestive System

Zi-hong CHEN; Hong LIU; Ming-wei LIU; Mi SHU; Qiong NAN

doi:10.12259/j.issn.2095-610X.S20210334

Volume 42 Issue 3

Apr. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(3): 145-148

Zi-hong CHEN, Hong LIU, Ming-wei LIU, Mi SHU, Qiong NAN. Research Progress of miRNA-145 in Malignant Tumors of Digestive System[J]. Journal of Kunming Medical University, 2021, 42(3): 145-148. doi: 10.12259/j.issn.2095-610X.S20210334

Citation:

Zi-hong CHEN, Hong LIU, Ming-wei LIU, Mi SHU, Qiong NAN. Research Progress of miRNA-145 in Malignant Tumors of Digestive System[J]. Journal of Kunming Medical University, 2021, 42(3): 145-148. doi: 10.12259/j.issn.2095-610X.S20210334

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Research Progress of miRNA-145 in Malignant Tumors of Digestive System

doi: 10.12259/j.issn.2095-610X.S20210334

Dept. of Gastroenterology，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

Received Date: 2020-12-19
Publish Date: 2021-04-09

Abstract

Abstract

MiRNA-145 is down-regulated in most malignant tumors of the digestive system and is widely considered as a tumor suppressor that can inhibit the growth of different tumor cells by acting on various cytokines and targeting various genes in multiple pathways, it can significantly reduce the proliferation of tumor cells, improve the sensitivity of tumor cells to chemotherapeutic drugs, and then exert its anti-tumor effect. In this paper, the expression and role of miRNA-145 in malignant tumors of digestive system were reviewed.
- miRNAs,
- miRNA-145,
- Digestive system malignancy

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References(21)

References

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