Analysis of Serum Fat-soluble Vitamin Levels in Infants and Children in Anning City

Yan GAO; Xiang-lei TONG; Hao-ran TANG; Li WU

doi:10.12259/j.issn.2095-610X.S20210408

Volume 42 Issue 4

Apr. 2021

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Yan GAO, Xiang-lei TONG, Hao-ran TANG, Li WU. Analysis of Serum Fat-soluble Vitamin Levels in Infants and Children in Anning City[J]. Journal of Kunming Medical University, 2021, 42(4): 44-48. doi: 10.12259/j.issn.2095-610X.S20210408

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Yan GAO, Xiang-lei TONG, Hao-ran TANG, Li WU. Analysis of Serum Fat-soluble Vitamin Levels in Infants and Children in Anning City[J]. Journal of Kunming Medical University, 2021, 42(4): 44-48. doi: 10.12259/j.issn.2095-610X.S20210408

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Analysis of Serum Fat-soluble Vitamin Levels in Infants and Children in Anning City

doi: 10.12259/j.issn.2095-610X.S20210408

Dept. of Pediatrics，Yunnan Kungang Hospital，Anning Yunnan 650302，China

Received Date: 2021-02-03
Publish Date: 2021-04-01

Abstract

Abstract

Objective To investigate the serum fat-soluble vitamins levels in infants and children in Anning City, to provide reference data for reasonable fat-soluble vitamin supplementation. Methods From June 2019 to July 2020, 925 infants and children from Children’ s Physical Examination Center of Kungang Hospital were selected. High performance liquid chromatography-tandem mass spectrometry （HPLC-MS/MS） was used to test the serum fat-soluble vitamins quantitatively. Then the fat-soluble vitamins levels were analyzed based on different ages, genders, and seasons. Results The average levels as well as insufficiency and deficient rates of serum vitamin A, 25-hydroxyvitamin D3, vitamin E and vitamin K in 925 infants and children were （284±3.84） ng/mL, 61.08%（565/925）; （34.27±0.46）ng/mL, 1.73%（16/925）; （8.47±0.16）μg/mL, 12.11%（112/925） and （0.46±0.03）ng/mL, 19.68%（182/925）, respectively. There were differences between different age groups （age range 0-3, 4-6, 7-12） and seasons （P < 0.01）. Conclusion There was a serious deficiency of vitamin A, which requires close attention and reasonable supplement. Due to the natural sunshine advantage in Yunnan, vitamin D nutrition level is relatively good, and excessive supplementation should be avoided.
- Children,
- Vitamin A,
- Vitamin D,
- Vitamin E,
- Vitamin K

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References(24)

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