Efficacy of Double Tract Reconstruction of Proximal Gastrectomy and Radical Total Gastrectomy of Upper Gastric Cancer

Ye YUAN; Jian CHANG; Dong-bo LIU; Bao-cheng JIANG

doi:10.12259/j.issn.2095-610X.S20210419

Volume 42 Issue 4

Apr. 2021

Turn off MathJax

Article Contents

Article Navigation > Journal of Kunming Medical University > 2021 > 42(4): 102-106

Ye YUAN, Jian CHANG, Dong-bo LIU, Bao-cheng JIANG. Efficacy of Double Tract Reconstruction of Proximal Gastrectomy and Radical Total Gastrectomy of Upper Gastric Cancer[J]. Journal of Kunming Medical University, 2021, 42(4): 102-106. doi: 10.12259/j.issn.2095-610X.S20210419

Citation:

Ye YUAN, Jian CHANG, Dong-bo LIU, Bao-cheng JIANG. Efficacy of Double Tract Reconstruction of Proximal Gastrectomy and Radical Total Gastrectomy of Upper Gastric Cancer[J]. Journal of Kunming Medical University, 2021, 42(4): 102-106. doi: 10.12259/j.issn.2095-610X.S20210419

Citation:

PDF( 634 KB)

Efficacy of Double Tract Reconstruction of Proximal Gastrectomy and Radical Total Gastrectomy of Upper Gastric Cancer

doi: 10.12259/j.issn.2095-610X.S20210419

Dept. of General Surgery，Suzhou Jiulong Hospital，Shanghai Jiaotong University School of Medicine，Suzhou Jiangsu 215028，China

Received Date: 2020-12-18
Publish Date: 2021-04-01

Abstract

Abstract

Objective To study the efficacy of proximal gastrectomy with double tract reconstruction and total radical gastrectomy for upper gastric cancer. Methods 50 patients who underwent radical resection of upper gastric cancer in Suzhou Jiulong Hospital from April 2014 to April 2019 were included in the study and were randomly divided into two groups. Observation group （25 cases） underwent radical proximal gastrectomy and double-tract reconstruction, and control group （25 cases） underwent total radical gastrectomy. Intraoperative blood loss, operation time, postoperative anal exhaust time, postoperative feeding time, postoperative ambulance time and postoperative hospitalization were observed and recorded in the two groups. The incidence of postoperative complications, single food intake, body weight, the ratio of serum pepsin type Ⅰ to Ⅱ, serum gastrin, hemoglobin and plasma albumin were compared between the two groups before and 6 months after operation. Results The intraoperative blood loss, operation time, postoperative ambulation time and postoperative hospitalization in the observation group were significantly lower than those in the control group （P < 0.05）; there was no significant difference in the first anal exhaust time and postoperative eating time between the two groups （P > 0.05）. The incidence of adverse reactions in the two groups were 20.00% and 36.00%, respectively. There was no significant difference between the two groups （P > 0.05）. 6 months after operation, amount of food intake per meal, serum gastrin, serum pepsin typeⅠ/Ⅱ were significantly lower than those before operation （P < 0.05）. Six months after operation, the serum gastrin in observation group was significantly higher than that in control group （P < 0.05）, and there was no statistical significance in the amount of food intake per meal and the pepsin typeⅠ/Ⅱ of serum compared with control group （P > 0.05）. The hemoglobin, plasma albumin and body mass at 6 months after operation in the two groups were significantly lower than those before operation （P < 0.05）; the hemoglobin, plasma albumin and body mass of the observation group at 6 months after operation were significantly higher than those of the control group （P < 0.05）. Conclusion Double tract reconstruction of proximal gastrectomy preserved function of the stomach and duodenum, so the patient has a better long-term nutritional status. The operation procedure is relatively easy causing less injury to patients. Therefore, it is an ideal way to reconstruct digestive tract in the radical operation of upper gastric carcinoma.
- Upper gastric cancer,
- Double tract reconstruction of Proximal gastrectomy,
- Complication

FullText(HTML)

References(19)

References

[1]	张晋杰,王杰,胡文庆. 进展期胃上部癌淋巴结清扫的现状与研究进展[J]. 中华胃肠外科杂志,2018,21(2):236-240. doi: 10.3760/cma.j.issn.1671-0274.2018.02.024
[2]	聂孟良,李铭,杨萌,等. 中老年胃癌根治术后发生胆囊炎的危险因素分析[J]. 中国肿瘤外科杂志,2017,9(6):373-375. doi: 10.3969/j.issn.1674-4136.2017.06.010
[3]	Ma X,Zhou W,Wang C,et al. Clinicopathologic characteristics in patients with upper third gastric cancer following radical surgical treatment:A retrospective cohort study[J]. Medicine(Baltimore),2018,97(45):13-17.
[4]	樊林. 食管胃结合部腺癌手术技术:双通道重建在早期食管胃结合部腺癌手术中的应用[J]. 中华胃肠外科杂志,2019,22(2):129-129.
[5]	国家“863”重大项目“胃癌分子分型与个体化诊疗”课题组. 胃癌病理分型和诊断标准的建议[J]. 中华病理学杂志,2010,39(4):266-269. doi: 10.3760/cma.j.issn.0529-5807.2010.04.013
[6]	Tao K,Dong J H. Phase I clinical research of jejunal interposition in adenocarcinoma of the esophagogastric junction II/III proximal gastrectomy[J]. Gastroenterol Res Pract,2016,32(6):346-350.
[7]	沈阳,程元光,文刚. 脾脏托出式脾门淋巴结清扫在中上部胃癌根治术中的应用[J]. 中华胃肠外科杂志,2017,20(1):108-109. doi: 10.3760/cma.j.issn.1671-0274.2017.01.025
[8]	任俭,崔建明,黄俊杰,等. 近端胃切除残胃空肠双通道吻合术的疗效与安全性研究[J]. 皖南医学院学报,2019,38(3):264-267. doi: 10.3969/j.issn.1002-0217.2019.03.017
[9]	陶凯,黄庆兴,张万红,等. Siewert Ⅱ型和Ⅲ型食管胃结合部腺癌近端胃切除术间置空肠单通道和双通道消化道重建的前瞻性随机对照研究[J]. 中华消化外科杂志,2018,17(8):830-835. doi: 10.3760/cma.j.issn.1673-9752.2018.08.011
[10]	陈芸,张双平,郭石平,等. 食管胃结合部腺癌269例根治术后生存分析[J]. 肿瘤研究与临床,2017,29(12):819-823. doi: 10.3760/cma.j.issn.1006-9801.2017.12.006
[11]	Long A J,Burton P R,De V M,et al. Radical gastric cancer surgery results in widespread upregulation of pro-tumourigenic intraperitoneal cytokines[J]. ANZ J Surg,2018,88(5):370-376. doi: 10.1111/ans.14267
[12]	庞霄君,丁秋龙,潘文胜. 早期食管癌内镜黏膜下剥离术后胃体上部穿孔一例诊治分析[J]. 实用肿瘤杂志,2019,34(3):267-269.
[13]	Bencivenga M,Verlato G,Han D S,et al. Validation of two prognostic models for recurrence and survival after radical gastrectomy for gastric cancer[J]. Br J Surg,2017,104(9):1235-1243. doi: 10.1002/bjs.10551
[14]	赵志强,李双喜,李子禹,等. 新辅助治疗对局部进展期胃上部癌D2根治术淋巴结获取的影响[J]. 中华消化外科杂志,2018,17(4):372-376. doi: 10.3760/cma.j.issn.1673-9752.2018.04.010
[15]	武锋,徐钧,贾凯. 完全腹腔镜与开腹全胃D2根治术治疗局部进展期胃上部癌近期疗效比较[J]. 肿瘤研究与临床,2019,31(4):237-240. doi: 10.3760/cma.j.issn.1006-9801.2019.04.005
[16]	庄立国. 全胃切除术与近端胃切除术治疗胃上部癌的临床效果对比分析[J]. 中国医药指南,2018,16(31):152-153.
[17]	Schouwenburg M G,Busweiler L A D,Beck N,et al. Hospital variation and the impact of postoperative complications on the use of perioperative chemo(radio)therapy in resectable gastric cancer. Results from the dutch upper gI cancer audit[J]. Eur J Surg Oncol,2018,44(4):532-538. doi: 10.1016/j.ejso.2018.01.008
[18]	黄昌明,郑志芳,林密. 腹腔镜胃癌根治术保脾脾门淋巴结清扫术[J]. 中华普外科手术学杂志(电子版),2017,11(6):464-464. doi: 10.3877/cma.j.issn.1674-3946.2017.06.004.
[19]	王宪中,赵迎威,李冬冬,等. 腹腔镜辅助胃癌根治术淋巴结清扫效果的临床对比[J]. 黑龙江医学,2017,41(3):234-235. doi: 10.3969/j.issn.1004-5775.2017.03.019

Relative Articles(20)

Relative Articles

[1]	Xiaoying CAI, Yi SHEN, Mengjiao GONG, Na LI. Comparison of Efficacy and Postoperative Complications of Lauromacrogol Foam Sclerosant and Lauromacrogol Injection in Patients with Internal Hemorrhoids. Journal of Kunming Medical University, 2022, 43(12): 137-141. doi: 10.12259/j.issn.2095-610X.S20221225
[2]	Yuxiao XIA, Xiuli FENG, Wei GUO, Shanjiao ZHONG, Yu DING, Manman DONG, Xuewei YANG, Ying ZHOU. Comparison of Frailty Assessment Methods for Predicting Postoperative Complications in Hospitalized Elderly Patients. Journal of Kunming Medical University, 2022, 43(7): 121-127. doi: 10.12259/j.issn.2095-610X.S20220723
[3]	Yunrui GUO, Hao YANG, Yecai ZHANG, Guoyun ZHANG, Decai WANG, Shulan JIAO, Ningli ZHANG, Chen ZHOU. Effect of Abdominal Regional Block Combined with Intravenous Analgesia on Postoperative Complications In Elderly Patients. Journal of Kunming Medical University, 2022, 43(12): 117-124. doi: 10.12259/j.issn.2095-610X.S20221222
[4]	Zhu-mei CHEN, Yue-ying HUA, Yan-yan WEN, Hui LI. The Incidence and Influencing Factors of Complications in Patients with Ultrasound-guided PICC Catheterization. Journal of Kunming Medical University, 2021, 42(2): 173-178. doi: 10.12259/j.issn.2095-610X.S20210209
[5]	Li Zhi Ling , Wang Xin Wen . . Journal of Kunming Medical University, 2020, 41(03): 116-120.
[6]	Huang Song Xia . The Effect of Evidence-based Care on the Complication Rate and Comfort in Patients with Coronary Heart Disease after Intervention Therapy. Journal of Kunming Medical University,
[7]	Zhan Zi Lan . Influence of Nursing Intervention on Mental State, Complications and Satisfaction in Patients with Cerebral Hemorrhage. Journal of Kunming Medical University,
[8]	Wang Juan . Influence of Comprehensive Nursing Intervention on Clinical Efficacy and Complications of Patients with Nephrotic Syndrome. Journal of Kunming Medical University,
[9]	Xiong Shou Qing . Comparison of Curative Effects and Complications of Coronary Intervention through Radial Artery and Femoral Artery. Journal of Kunming Medical University,
[10]	Li Pei . The Analysis of Using Modified Clavien Classification of Surgical Complications in Postoperative Complications of Mini-Percutaneous Nephrolithotomy. Journal of Kunming Medical University,
[11]	Li Yue Hua . . Journal of Kunming Medical University,
[12]	Huang Yun . . Journal of Kunming Medical University,
[13]	Jiang Yan Bing . . Journal of Kunming Medical University,
[14]	Liu Le Wan . . Journal of Kunming Medical University,
[15]	Wang Hong Yue . . Journal of Kunming Medical University,
[16]	Jin Zhi Xian . . Journal of Kunming Medical University,
[17]	Zhang Yue Ping . . Journal of Kunming Medical University,
[18]	Zhang Yue Ping . . Journal of Kunming Medical University,
[19]	Li Zhi Jun . . Journal of Kunming Medical University,
[20]	Xiao Xu Hui . . Journal of Kunming Medical University,