Volume 42 Issue 4
Apr.  2021
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Ye YUAN, Jian CHANG, Dong-bo LIU, Bao-cheng JIANG. Efficacy of Double Tract Reconstruction of Proximal Gastrectomy and Radical Total Gastrectomy of Upper Gastric Cancer[J]. Journal of Kunming Medical University, 2021, 42(4): 102-106. doi: 10.12259/j.issn.2095-610X.S20210419
Citation: Ye YUAN, Jian CHANG, Dong-bo LIU, Bao-cheng JIANG. Efficacy of Double Tract Reconstruction of Proximal Gastrectomy and Radical Total Gastrectomy of Upper Gastric Cancer[J]. Journal of Kunming Medical University, 2021, 42(4): 102-106. doi: 10.12259/j.issn.2095-610X.S20210419

Efficacy of Double Tract Reconstruction of Proximal Gastrectomy and Radical Total Gastrectomy of Upper Gastric Cancer

doi: 10.12259/j.issn.2095-610X.S20210419
  • Received Date: 2020-12-18
  • Publish Date: 2021-04-01
  •   Objective  To study the efficacy of proximal gastrectomy with double tract reconstruction and total radical gastrectomy for upper gastric cancer.  Methods  50 patients who underwent radical resection of upper gastric cancer in Suzhou Jiulong Hospital from April 2014 to April 2019 were included in the study and were randomly divided into two groups. Observation group (25 cases) underwent radical proximal gastrectomy and double-tract reconstruction, and control group (25 cases) underwent total radical gastrectomy. Intraoperative blood loss, operation time, postoperative anal exhaust time, postoperative feeding time, postoperative ambulance time and postoperative hospitalization were observed and recorded in the two groups. The incidence of postoperative complications, single food intake, body weight, the ratio of serum pepsin type Ⅰ to Ⅱ, serum gastrin, hemoglobin and plasma albumin were compared between the two groups before and 6 months after operation.  Results  The intraoperative blood loss, operation time, postoperative ambulation time and postoperative hospitalization in the observation group were significantly lower than those in the control group (P < 0.05); there was no significant difference in the first anal exhaust time and postoperative eating time between the two groups (P > 0.05). The incidence of adverse reactions in the two groups were 20.00% and 36.00%, respectively. There was no significant difference between the two groups (P > 0.05). 6 months after operation, amount of food intake per meal, serum gastrin, serum pepsin typeⅠ/Ⅱ were significantly lower than those before operation (P < 0.05). Six months after operation, the serum gastrin in observation group was significantly higher than that in control group (P < 0.05), and there was no statistical significance in the amount of food intake per meal and the pepsin typeⅠ/Ⅱ of serum compared with control group (P > 0.05). The hemoglobin, plasma albumin and body mass at 6 months after operation in the two groups were significantly lower than those before operation (P < 0.05); the hemoglobin, plasma albumin and body mass of the observation group at 6 months after operation were significantly higher than those of the control group (P < 0.05).  Conclusion  Double tract reconstruction of proximal gastrectomy preserved function of the stomach and duodenum, so the patient has a better long-term nutritional status. The operation procedure is relatively easy causing less injury to patients. Therefore, it is an ideal way to reconstruct digestive tract in the radical operation of upper gastric carcinoma.
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