Correlation between Urinary Iodine and Thyroid Diseases

YAN TANG; Bo-yi LI; Rong MA; Ling NIU; Fang LIU; Cui-juan MIAO

doi:10.12259/j.issn.2095-610X.S20210425

Volume 42 Issue 4

Apr. 2021

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YAN TANG, Bo-yi LI, Rong MA, Ling NIU, Fang LIU, Cui-juan MIAO. Correlation between Urinary Iodine and Thyroid Diseases[J]. Journal of Kunming Medical University, 2021, 42(4): 134-137. doi: 10.12259/j.issn.2095-610X.S20210425

Citation:

YAN TANG, Bo-yi LI, Rong MA, Ling NIU, Fang LIU, Cui-juan MIAO. Correlation between Urinary Iodine and Thyroid Diseases[J]. Journal of Kunming Medical University, 2021, 42(4): 134-137. doi: 10.12259/j.issn.2095-610X.S20210425

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Correlation between Urinary Iodine and Thyroid Diseases

doi: 10.12259/j.issn.2095-610X.S20210425

Dept. of Endocrinology，The 1st People’s Hospital of Kunmig，Kunming Yunnan 650031，China

Received Date: 2020-12-19
Publish Date: 2021-04-25

Abstract

Abstract

Objective To investigate the correlation between urinary iodine and thyroid diseases. Method A total of 266 patients who received physical check-up or treatment in the Department of Endocrinology of our hospital from January to December 2018 were enrolled in the study. Patients were divided into a thyroid disease group （207 cases） and non thyroid disease group （59 cases）; and urine iodine and thyroid stimulating hormone （TSH）, free triiodothyronine （FT3）, and free thyroid Levels of FT4, triiodothyronine （T3）, tetraiodothyronine （T4）, thyroid peroxidase antibody （TPOAb）, thyroglobulin antibody （TGAb） level are detected. Color doppler ultrasound was used to check patients thyroid. SPSS17.0 software was used for t test, rank sum test and χ² test; and multivariate Logistic regression analysis was used for the incidence factors of thyroid diseases. Results The median urinary iodine level （143.30 ug/L） of the thyroid disease group was significantly lower than that of the non-thyroid disease group （178.30 ug/L, P < 0.05）; multivariate logistic regression analysis results showed that age （ OR= 1.140, 95%CI: 1.033-1.257, P = 0.009）, urine iodine （OR= 0.983, 95%CI: 0.971-0.996, P = 0.008） and TPOAb （OR = 1.018, 95%CI: 0.979-1.059, P = 0.020） were independent risk factors for thyroid disease. Conclusion Low levels of urinary iodine are related to the prevalence of thyroid diseases. Urinary iodine, TPOAb and age are independent risks factors of thyroid diseases.
- Urinary iodine,
- Thyroid peroxidase antibody（TPOAb）,
- Thyroid disease

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References(14)

References

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