Correlation between Urinary Iodine and Thyroid Diseases

YAN TANG; Bo-yi LI; Rong MA; Ling NIU; Fang LIU; Cui-juan MIAO

doi:10.12259/j.issn.2095-610X.S20210425

Volume 42 Issue 4

Apr. 2021

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YAN TANG, Bo-yi LI, Rong MA, Ling NIU, Fang LIU, Cui-juan MIAO. Correlation between Urinary Iodine and Thyroid Diseases[J]. Journal of Kunming Medical University, 2021, 42(4): 134-137. doi: 10.12259/j.issn.2095-610X.S20210425

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YAN TANG, Bo-yi LI, Rong MA, Ling NIU, Fang LIU, Cui-juan MIAO. Correlation between Urinary Iodine and Thyroid Diseases[J]. Journal of Kunming Medical University, 2021, 42(4): 134-137. doi: 10.12259/j.issn.2095-610X.S20210425

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Correlation between Urinary Iodine and Thyroid Diseases

doi: 10.12259/j.issn.2095-610X.S20210425

Dept. of Endocrinology，The 1st People’s Hospital of Kunmig，Kunming Yunnan 650031，China

Received Date: 2020-12-19
Publish Date: 2021-04-25

Abstract

Abstract

Objective To investigate the correlation between urinary iodine and thyroid diseases. Method A total of 266 patients who received physical check-up or treatment in the Department of Endocrinology of our hospital from January to December 2018 were enrolled in the study. Patients were divided into a thyroid disease group （207 cases） and non thyroid disease group （59 cases）; and urine iodine and thyroid stimulating hormone （TSH）, free triiodothyronine （FT3）, and free thyroid Levels of FT4, triiodothyronine （T3）, tetraiodothyronine （T4）, thyroid peroxidase antibody （TPOAb）, thyroglobulin antibody （TGAb） level are detected. Color doppler ultrasound was used to check patients thyroid. SPSS17.0 software was used for t test, rank sum test and χ² test; and multivariate Logistic regression analysis was used for the incidence factors of thyroid diseases. Results The median urinary iodine level （143.30 ug/L） of the thyroid disease group was significantly lower than that of the non-thyroid disease group （178.30 ug/L, P < 0.05）; multivariate logistic regression analysis results showed that age （ OR= 1.140, 95%CI: 1.033-1.257, P = 0.009）, urine iodine （OR= 0.983, 95%CI: 0.971-0.996, P = 0.008） and TPOAb （OR = 1.018, 95%CI: 0.979-1.059, P = 0.020） were independent risk factors for thyroid disease. Conclusion Low levels of urinary iodine are related to the prevalence of thyroid diseases. Urinary iodine, TPOAb and age are independent risks factors of thyroid diseases.
- Urinary iodine,
- Thyroid peroxidase antibody（TPOAb）,
- Thyroid disease

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[1]	梁建. 我国云南最早尝试食盐加碘防治碘缺乏病的历史[J]. 中华地方病学杂志,2009,38(2):165-167. doi: 10.3760/cma.j.issn.1000-4955.2009.02.013
[2]	腾卫平. 防治碘缺乏病与碘过量[J]. 中华内分泌代谢杂志,2002,18(3):239-242.
[3]	孙川喻,陆烨君,阮慧娟,等. 成人碘营养状况评价以及与甲状腺结节的相关性[J]. 中华临床营养杂志,2016,24(2):76-81.
[4]	Konig F,Andersson M,Hotz K,et al. Ten repeat collections for urinary iodine from spot samples or 24-hour samples are needed to reliably estimate individual iodine status in women[J]. The Journal of Nutrition,2011,141(11):2049-2054. doi: 10.3945/jn.111.144071
[5]	陈赟. 尿碘与甲状腺疾病相关性研究进展[J]. 临床与病理杂志,2016,36(9):1423-1429. doi: 10.3978/j.issn.2095-6959.2016.09.034
[6]	中华医学会内分泌学分会《中国甲状腺疾病诊治指南》编写组. 中国甲状腺疾病诊治指南—碘缺乏病[J]. 中华内科杂志,2008,47(8):689-690.
[7]	滕卫平. 再论碘摄入量增加对甲状腺疾病的影响[J]. 中华内分泌代谢杂志,2001,17(2):69-70. doi: 10.3760/j.issn:1000-6699.2001.02.002
[8]	孙殿军. 论中国地方病控制之前景[J]. 中国地方病学杂志,2009,28(1):3-6.
[9]	王安伟,黄文丽,叶枫,等. 云南省食盐碘含量调整前后儿童碘营养状况调查[J]. 中华地方病学杂志,2018,37(1):49-53. doi: 10.3760/cma.j.issn.2095-4255.2018.01.011
[10]	陈冬,邓大同,陈明卫. TPO/TPO抗体与甲状腺疾病相关性[J]. 安徽医药,2011,15(1):1-3. doi: 10.3969/j.issn.1009-6469.2011.01.001
[11]	Dong Y H,Fu D G. Autoimmune thyroid disease:Mechanism,genetics and current knowledge[J]. Eur Rev Med Pharmacol Sci,2014,18(23):3611-3618.
[12]	刘婷婷,滕卫平. 中国国民碘营养现状与甲状腺疾病[J]. 中华内科杂志,2017,56(1):62-64. doi: 10.3760/cma.j.issn.0578-1426.2017.01.018
[13]	王娟娟,贾清珍,张向东,等. 尿碘与甲状腺疾病相关性的研究[J]. 中华地方病学杂志,2013,32(4):359-361. doi: 10.3760/cma.j.issn.2095-4255.2013.04.002
[14]	薛利敏. 女性自身免疫性甲状腺炎患者的尿碘水平及硒、碘干预效果评价[D]. 唐山: 华北理工大学硕士学位论文, 2017.

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