Effect of Acetone in Human Blood on Ethanol Detection Results

Yan-ming REN; Ji-bin XIONG; Chen-fei ZHAO; Chen-xi LI; An-qi GUAN; Zi-qing XU; Kai-bo ZHANG; Rui-lin ZHANG; Shu-hua LI

doi:10.12259/j.issn.2095-610X.S20210428

Volume 42 Issue 4

Apr. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(4): 146-149

Yan-ming REN, Ji-bin XIONG, Chen-fei ZHAO, Chen-xi LI, An-qi GUAN, Zi-qing XU, Kai-bo ZHANG, Rui-lin ZHANG, Shu-hua LI. Effect of Acetone in Human Blood on Ethanol Detection Results[J]. Journal of Kunming Medical University, 2021, 42(4): 146-149. doi: 10.12259/j.issn.2095-610X.S20210428

Citation:

Yan-ming REN, Ji-bin XIONG, Chen-fei ZHAO, Chen-xi LI, An-qi GUAN, Zi-qing XU, Kai-bo ZHANG, Rui-lin ZHANG, Shu-hua LI. Effect of Acetone in Human Blood on Ethanol Detection Results[J]. Journal of Kunming Medical University, 2021, 42(4): 146-149. doi: 10.12259/j.issn.2095-610X.S20210428

Citation:

Yan-ming REN, Ji-bin XIONG, Chen-fei ZHAO, Chen-xi LI, An-qi GUAN, Zi-qing XU, Kai-bo ZHANG, Rui-lin ZHANG, Shu-hua LI. Effect of Acetone in Human Blood on Ethanol Detection Results[J]. Journal of Kunming Medical University, 2021, 42(4): 146-149. doi: 10.12259/j.issn.2095-610X.S20210428

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Effect of Acetone in Human Blood on Ethanol Detection Results

doi: 10.12259/j.issn.2095-610X.S20210428

Forensic Expertise Center/School of Forensic Medicine，Kunming Medical University，Kunming Yunnan 650500，China

Received Date: 2020-12-14
Publish Date: 2021-04-01

Abstract

Abstract

Objective To study the effect of acetone in blood samples on the qualitative and quantitative results of ethanol. Methods Headspace gas chromatography （double column and double detector） was used to determine ethanol and acetone in blood samples of 600 suspected drunk drivers or driving after drinking drivers. Results In column 1 （DB-ALC1）, internal standard tert-butanol and acetone could be separated effectively; while in column 2 （DB-ALC2）, acetone could not be separated from the internal standard tert-butanol, which interferes with the accuracy of the ethanol quantitative results. Some blood samples suspected to contain acetone tested in this study were confirmed by GC-MS, and all acetone components were detected positive. The acetone concentration in 113 blood samples were detected by GC. The highest acetone content in the blood samples was 6.55mg/100mL. Conclusion In forensic medical identification, attention should be paid to the influence of acetone on the detection results of ethanol. In order to accurately identify the fact of driving after drinking and drunk driving cases, double-column dual detectors should be used for qualitative determination of ethanol. In the presence of acetone, the mean value of DB-ALC1 column was used as quantitative results.
- Headspace gas chromatography,
- Blood,
- Ethanol,
- Acetone

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References(15)

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