Volume 42 Issue 6
Jul.  2021
Turn off MathJax
Article Contents
Bin LIU, Xian-gang LI, Min ZHANG, Fang ZHOU, Ren-hua LIN, Jie YANG, Liang ZHANG, Xian-kun WANG, Ya-nan PAN. Main Influencing Factors of the Second Hospitalization of Patients with Coronary Heart Disease[J]. Journal of Kunming Medical University, 2021, 42(6): 103-109. doi: 10.12259/j.issn.2095-610X.S20210618
Citation: Bin LIU, Xian-gang LI, Min ZHANG, Fang ZHOU, Ren-hua LIN, Jie YANG, Liang ZHANG, Xian-kun WANG, Ya-nan PAN. Main Influencing Factors of the Second Hospitalization of Patients with Coronary Heart Disease[J]. Journal of Kunming Medical University, 2021, 42(6): 103-109. doi: 10.12259/j.issn.2095-610X.S20210618

Main Influencing Factors of the Second Hospitalization of Patients with Coronary Heart Disease

doi: 10.12259/j.issn.2095-610X.S20210618
  • Received Date: 2021-02-08
  • Publish Date: 2021-06-25
  •   Objective   To evaluate the causes and influencing factors of re-hospitalization of patients with coronary heart disease by coronary angiography, so as to guide clinical diagnosis and treatment decisions and reduce re-hospitalization.   Methods   From January 2013 to December 2019, a total of 316 patients who were hospitalized twice with coronary angiography and/or percutaneous coronary intervention were analyzed retrospectively, including 235 males and 81 females, with a male to female ratio of 2.9∶1. According to the times of hospitalization, they were divided into the first hospitalization group and the second hospitalization group, with an average age of 59.45 ±10.09 years and 60.47±10.16 years. The average time interval between the two hospitalizations was 14.30±11.67 months. Among them, 265 patients were diagnosed with coronary heart disease for the first time and percutaneous coronary intervention (PCI), accounting for 83%.   Results   After two hospitalizations, there were significant differences in LDL-C, TG, diabetes history smoking history, drinking history, first-time clinical diagnosis, severity of lesion (Gensini score) of each blood vessel (LAD, RCA, LCX), and stent placement of each blood vessel between the two groups (P < 0.05). The number of diabetic patients increased during the second hospitalization, with significant difference ( P < 0.05) Multivariate Logistic regression analysis showed that LDL-C control was not up to standard, and the low rate of reaching the standard (13.3%, 31.0%) was an independent risk factor affecting the second hospitalization of patients with coronary heart disease (OR = 1.985, 95%CI 1.506~2.617). RCA, LAD and LCX were the protective factors for the second hospitalization of patients with coronary heart disease [(OR = 0.304, 95%CI 0.144~0.642), (OR = 0.184, 95%CI 0.099~0.343), (OR = 0.228, 95%CI 0.123~0.424)] Compared with those who were diagnosed as ST-segment elevation myocardial infarction (STEMI) for the first time, active revascularization treatment was a protective factor for re-hospitalization of patients who were diagnosed as stable angina pectoris (SAP), unstable angina pectoris (UAP) and non-ST-segment elevation myocardial infarction (NSTEMI) again [(OR = 0.071, 95%CI 0.031~0.163), OR = 0.323, 95%CI 0.117~0.743, P < 0.05]. However, there was no significant difference in age, TC, HDL-C, Cre, BUN, UA, FPG, hypertension and vascular diseases of various coronary arteries ( P > 0.05).   Conclusion   Strict control of LDL-C level in patients with coronary heart disease can effectively prevent and control the progress of diabetes, and actively carry out effective revascularization on seriously diseased coronary vessels during the first hospitalization can reduce the occurrence of second hospitalization.
  • loading
  • [1]
    中国心血管健康与疾病报告2019[J]. 中国心血管健康与疾病报告2019[J]. 心肺血管病杂志,2020,39(10):1157-1162.
    [2]
    王笑梅,肖航,唐刚,等. 重庆地区老年冠心病患者治疗方案与中远期再入院率的相关性[J]. 中华老年多器官疾病杂志,2013,12(6):417-421.
    [3]
    顾昕. “健康中国”战略中基本卫生保健的治理创新[J]. 中国社会科学,2019(12):121-138+202.
    [4]
    中国高血压防治指南(2018年修订版)[J]. 中国高血压防治指南(2018年修订版)[J]. 中国心血管杂志,2019,24(01):24-56. doi: 10.3969/j.issn.1007-5410.2019.01.002
    [5]
    中国2型糖尿病防治指南(2017年版)[J]. 中国2型糖尿病防治指南(2017年版)[J]. 中华糖尿病杂志,2018,10(01):4-67. doi: 10.3760/cma.j.issn.1674-5809.2018.01.003
    [6]
    慢性稳定性心绞痛诊断与治疗指南[J]. 慢性稳定性心绞痛诊断与治疗指南[J]. 中华心血管病杂志,2007,35(3):195-206. doi: 10.3760/j.issn:0253-3758.2007.03.002
    [7]
    柯元南,陈纪林. 不稳定性心绞痛和非ST段抬高心肌梗死诊断与治疗指南[J]. 中华心血管病杂志,2007,35(4):295-304. doi: 10.3760/j.issn:0253-3758.2007.04.003
    [8]
    中华医学会心血管病学分会,中华心血管病杂志编辑委员会. 急性ST段抬高型心肌梗死诊断和治疗指南(2019)[J]. 中华心血管病杂志,2019,47(10):766-783.
    [9]
    Elyamani A S,Elnozahi M A,Abdelmoteleb A M. Correlation between Atherogenic index and the severity of coronary artery disease in diabetic patients undergoing elective coronary angiography using Gensini score[J]. QJM:An international journal of medicine,2020,113(Suppl1):136-137.
    [10]
    中华医学会心血管病学分会,中国康复医学会心脏预防与康复专业委员会,中国老年学和老年医学会心脏专业委员会. 中国心血管病一级预防指南[J]. 中国心血管病杂志,2020,48(12):1000-1038.
    [11]
    Elyamani A S,Elnozahi M A,Abdelmoteleb A M,et al. Correlation between Atherogenic index and the severity of coronary artery disease in diabetic patients undergoing elective coronary angiography using Gensini score[J]. QJM:An International Journal of Medicine,2020,113(1):41-42.
    [12]
    Tetsuro Yokokawa,Akiomi Yoshihisa,Takatoyo Kiko,et al. Gensini Score Is Associated With Long-Term Cardiac Mortality in Patients With Heart Failure After Percutaneous Coronary Intervention[J]. Circulation Reports,2020,2(2):89-94. doi: 10.1253/circrep.CR-19-0121
    [13]
    Brian A,Ference,John J P,et al. Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary HeartDisease[J]. JAMA,2019,321(4):364-373.
    [14]
    胡大一,于晓松,杜雪平,等. 血脂异常基层诊疗指南(2019年)[J]. 中华全科医师杂志,2019,18(5):406-416. doi: 10.3760/cma.j.issn.1671-7368.2019.05.003
    [15]
    Mach François,Baigent Colin,CatapanoAlberico L,et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias:lipid modification to reduce cardiovascular risk[J]. European Heart Journal,2020,41(1):111-188. doi: 10.1093/eurheartj/ehz455
    [16]
    曹爱霖, 许绍兰, 缪锦云, 等. 中国冠心病患者LDL-C达标与PCI术后冠脉再狭窄研究—一项基于真实世界的10年回顾性研究[C]. 第九届全国治疗药物监测学术年会论文摘要集. 2019: 1.
    [17]
    童江涛,夏勇. 急性心肌梗死患者再入院时冠状动脉造影特点分析[J]. 中国循证心血管医学杂志,2017,9(10):1204-1207. doi: 10.3969/j.issn.1674-4055.2017.10.16
  • Relative Articles

    [1] Shuangshuang XU, Wei ZHAO, Lei JIANG, Huajiang LIU, Fang WANG, Zhisheng TAN, Likun ZHOU. Correlation Between TyG Index,MHR and Coronary Lesions,Myocardial Ischemia in Patients with Coronary Heart Disease,and the Value of Combined Detection. Journal of Kunming Medical University, 2024, 45(3): 65-71.  doi: 10.12259/j.issn.2095-610X.S20240310
    [2] Wenqing MIAO, Yu WANG, Xiaoli ZHAO, Nini TIAN, Liying YOU. Analysis of Differential Gene Expression and Function in Peripheral Blood of Patients with Coronary Heart Disease and Acute Myocardial Infarction. Journal of Kunming Medical University, 2022, 43(6): 25-34.  doi: 10.12259/j.issn.2095-610X.S20220614
    [3] Jing TANG, Jun-chao HUANG, Ya-fei HUANG, Ming-zhu GENG, Xiao-qin MAO, Jian-ping PU. Application of Lipoprotein-associated Phospholipase A2 in Coronary Heart Disease Patients Taking Statins. Journal of Kunming Medical University, 2021, 42(12): 6-10.  doi: 10.12259/j.issn.2095-610X.S20211205
    [4] Dai Hai Long , Zhang Xing , Pan Yun , Feng Xiao Lan , Lu Xiang Ting , Guang Xue Feng , Yin Xiao Long . . Journal of Kunming Medical University, 2020, 41(04): 60-63.
    [5] Xu XU, Li-yong WU, Ming-li ZHOU, Guo-fu ZHU. Relationship between microRNA-146a and the Plaque Stability in Coronary Heart Disease Patients. Journal of Kunming Medical University, 2020, 41(11): 56-61.  doi: 10.12259/j.issn.2095-610X.S20201119
    [6] Zheng Lin Qiong , Lu Jing , Ye Ji Ming . . Journal of Kunming Medical University, 2019, 40(06): 90-92.
    [7] Zhang Huan , Zhou Xiao Yan , Zhang Lu Dan , Zhu Ye . . Journal of Kunming Medical University, 2019, 40(08): 57-62.
    [8] Wang Ji Yan , Duan Yong . . Journal of Kunming Medical University, 2018, 39(12): 1-4.
    [9] Li Lin , Li Ji Yi , Wang De Zhao , Liu Wei . 武汉地区123例冠心病患者CYP2C19基因多态性分布. Journal of Kunming Medical University, 2017, 38(06): 60-63.
    [10] Xiao Yi . The Clinical Effect of CDSP Treatment for Coronary Heart Disease. Journal of Kunming Medical University,
    [11] Li Wen Hua , Wei Yun Hong , Ye Ji Yun . Effect of Probiotics on Blood Lipid Metabolism of Elderly Patients with Coronary Heart Disease. Journal of Kunming Medical University, 2016, 37(12): 82-84.
    [12] Dai Qing Yuan . . Journal of Kunming Medical University,
    [13] Feng Yong Hong . . Journal of Kunming Medical University,
    [14] Zhou Kai Hua . . Journal of Kunming Medical University,
    [15] Tan Xiao Bing . . Journal of Kunming Medical University,
    [16] Yang Ping . . Journal of Kunming Medical University,
    [17] Li Hong Dao . . Journal of Kunming Medical University,
    [18] Lv Han Xian . Detection of Periodontopathogens in Subgingival Plaque of Patients with Coronary Heart Disease and Periodontitis. Journal of Kunming Medical University,
    [19] Yin Lin . . Journal of Kunming Medical University,
    [20] He Li Ping . . Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(2)

    Article Metrics

    Article views (4297) PDF downloads(27) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return