Volume 42 Issue 7
Jul.  2021
Turn off MathJax
Article Contents
Bo TIAN, Jun LIU, Chong-xi LI, Rong HE, Shan-qun GU, Wei-bo WANG. Effect of HIV Post-exposure Prophylaxis in Kunming City in 2019[J]. Journal of Kunming Medical University, 2021, 42(7): 126-129. doi: 10.12259/j.issn.2095-610X.S20210721
Citation: Bo TIAN, Jun LIU, Chong-xi LI, Rong HE, Shan-qun GU, Wei-bo WANG. Effect of HIV Post-exposure Prophylaxis in Kunming City in 2019[J]. Journal of Kunming Medical University, 2021, 42(7): 126-129. doi: 10.12259/j.issn.2095-610X.S20210721

Effect of HIV Post-exposure Prophylaxis in Kunming City in 2019

doi: 10.12259/j.issn.2095-610X.S20210721
  • Received Date: 2021-04-23
    Available Online: 2021-07-19
  • Publish Date: 2021-07-21
  •   Objective  To understand the treatment status and effect of HIV post-exposure prophylaxis in Kunming city in 2019. The proportion of the 28-day course completed and the influencing factors. It provides a reference for the wide application of HIV post-exposure prophylaxis.  Methods  Descriptive analysis was carried out on the data of HIV post-exposure prophylaxis in kunming city in 2019. Logistic analysis of factors affecting the completion of 28 days of treatment.  Results  The average age of 872 patients of HIV post-exposure prophylaxis was 32 (26, 36) years. Men accounted for 81.99%. Only 10.09% of people identified the infection source person with HIV. The proportion of patients with treatment FTC + DTG/RAL was 78.56%. The proportion of patients within 2 h was 2.87%, the proportion of patients within 2 h to 24 h was 63.88%. 78.56% completed the 28-day course. Unemployed, inactive and student patients were less likely to complete the 28-day course (OR = 1.668, P = 0.012); It is clear that patients who knew the infection source person with HIV infection are more likely to complete a 28-day course of treatment (OR = 0.166, P < 0.001). Only one of the 544 people who had test results or called then tested positive for HIV.  Conclusion  HIV post-exposure prophylaxis treatment is predominantly male, most do not know if the infection source person with HIV. Increasing economic income and identifying infection status are beneficial to increasing drug completion rate. At the same time, publicity and education should be strenghened to improve the timeliness and effectiveness of medical treatment.
  • loading
  • [1]
    王芳,张福杰. 人类免疫缺陷病毒(HIV)的暴露后预防[J]. 新发传染病电子杂志,2019,4(2):121-124.
    [2]
    张璐平,韩跃红. 艾滋病非职业暴露预防用药的伦理研究[J]. 中国医学伦理学,2017,30(12):1455-1459.
    [3]
    齐唐凯,卢洪洲. 加拿大人免疫缺陷病毒暴露前预防和非职业性暴露后预防指南解读[J]. 世界临床药物,2018,39(11):727-731.
    [4]
    杨新宇. 艾滋病暴露前预防与暴露后预防的应用与挑战[J]. 中国艾滋病性病,2019,25(4):425-428.
    [5]
    Tan D H S,Hull M W,Yoong D,et al. Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational post exposure prophylaxis[J]. C MA J,2017,189(47):E1448-E1458.
    [6]
    World Health Organization. Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV[EB/OL]. Geneva, 2015, (2017-10-19)[2018-08-30]. www.who.int/hiv/pub/guidelines/earlyrelease-arv/en.
    [7]
    揣征然,张云辉,赵雅琳,等. 全球及中国AIDS最新疫情概况[J]. 传染病信息,2020,33(06):501-503.
    [8]
    付朝智,肖璨,李佑芳,等. 昆明市MSM对艾滋病非职业暴露后预防用药的接受度调查[J]. 中国艾滋病性病,2020,26(12):1309-1312.
    [9]
    王春梅,段青,陈谦,等. 济南市接受 HIV非职业暴露预防男性就诊者高危行为及阻断效果研究[J]. 中国艾滋病性病,2018,24(12):1221-1223.
    [10]
    Lin S Y,Lachowsky N J,Hull M,et al. Awareness and use of non-occupational post-exposure prophylaxis among men who have sex with men in Vanvouver,Canada[J]. HIV Medicine,2016,17(9):662. doi: 10.1111/hiv.12369
    [11]
    中华医学会感染病学分会艾滋病丙型肝炎学组,中国疾病预防控制中心. 中国艾滋病诊疗指南(2018版)[J]. 国际流行病学传染病学杂志,2018,45(6):361-378.
    [12]
    WHO | World Health Organization. Post-exposure prophylaxis to prevent HIV infection [EB/OL]. [2020-03-08]. https://www.who.int/hiv/topics/prophylaxis/info/en/.
    [13]
    Malinverni S,Gennotte A F,Schuster M. et al. Adherence to HIV post-esposure prophylaxis:A multivariate regression analysis of a 5years prospective cohort[J]. J Infect,2018,576(1):78-85.
    [14]
    Valin N,Fonquernie L,Daguenel A,et al. Evaluation of tolerability with the co-formulation elvitegravir,cobicistat,emtricitabine,and tenofovir disoproxil fumarate for post-HIV exposure prophylaxis[J]. BMC Infect Dis,2016,16(1):718. doi: 10.1186/s12879-016-2056-3
    [15]
    Irvine C,Egan K J,Shubber Z,et al. Efficacy of HIV postexposure prophylaxis:Systematic review and meta-analysis of nonhuman primate studies[J]. Clin Infect Dis,2015,60(3):S165-169.
    [16]
    赵伟,李珍,田洪青. HIV暴露前预防和暴露后阻断[J]. 皮肤科学通报,2019,36(3):395-400.
  • Relative Articles

    [1] Baochuan HUANG, Wuquan LI, Yi TANG. An Epidemiological Analysis of 1500 Pediatric BurnsPatients at the Burn Center in Yunnan. Journal of Kunming Medical University, 2024, 45(10): 1-9.
    [2] Li WANG, Yajuan SHANG, Ting GAO, Hui FAN, Zhenfeng LIU. Visualization Analysis of Research Trends in Lower Extremity Deep Vein Thrombosis Based on Web of Science. Journal of Kunming Medical University, 2024, 46(): 1-9.
    [3] Yihan LIU, Jun LIU, Yongmei JIN, Bo TIAN, Jinsong BAI. Risk Assessment and Analysis of Risk Factors for Cardiovascular Disease in HIV Antiviral Therapy Patients. Journal of Kunming Medical University, 2024, 45(10): 140-146.  doi: 10.12259/j.issn.2095-610X.S20241022
    [4] Bo TIAN, Jun LIU, Chongxi LI, Wei ZHANG, Meiqin FANG, Haiyun CHEN, Jingping BAI, Xin ZHOU, Lei CHENG, Yongmei JIN. Effect Observation and Influencing Factors Analysis of Rapid Initiation of Antiretroviral Therapy. Journal of Kunming Medical University, 2024, 45(9): 163-167.  doi: 10.12259/j.issn.2095-610X.S20240925
    [5] Siwei YANG, Yan LI, Xia XIAO, Xiaoxiao SONG, Lin SUN, Rui MA. The Analysis of Exposure and Influencing Factors of Pyrethroid Pesticides in Rural Women during Different Pregnancy Stages in Xuanwei,Yunnan Province. Journal of Kunming Medical University, 2024, 45(11): 52-58.  doi: 10.12259/j.issn.2095-610X.S20241108
    [6] Xiaoyan WANG, Ya LI, Chenglu HE, Lin WANG, Zhiqiang MA, Xinrui WAN. Study on Immune Function and Drug Resistance of Tuberculosis Patients Co-infected with HBV,HCV and HIV in Yunnan. Journal of Kunming Medical University, 2023, 44(12): 51-58.  doi: 10.12259/j.issn.2095-610X.S20231209
    [7] Bo TIAN, Chongxi LI, Yongmei JIN, Wei GUAN, Haiyun CHEN, Jun LIU. Use and Replacement of Treatment Regimens for AIDS Patients on Antiretroviral Therapy. Journal of Kunming Medical University, 2023, 44(5): 162-167.  doi: 10.12259/j.issn.2095-610X.S20230508
    [8] Bo TIAN, Jun LIU, Haiwen LI, Wei SONG, Haiyun CHEN, Jianjun SUN. Pathogen Distribution and Antimicrobial Susceptibility of Bacterial Bloodstream Infection in AIDS Patients. Journal of Kunming Medical University, 2022, 43(6): 140-146.  doi: 10.12259/j.issn.2095-610X.S20220616
    [9] Bo TIAN, Yinzhong SHEN, Jinsong BAI, Jun LIU, Haiyun CHEN, Jianjun SUN. Clinical Characteristics of Talaromyces Marneffei Disease and Disseminated Nontuberculosis Mycobacterium Disease in AIDS Patients. Journal of Kunming Medical University, 2022, 43(7): 140-144.  doi: 10.12259/j.issn.2095-610X.S20220718
    [10] Sun Lin , Xiao Xia , Li Yan , Yang Si Wei , Xu Qing Hua , Ma Rui , Wu Jie , Zhang Chao , Guo Guang Ping . Pyrethroid Exposure and Related Factors among Pregnant Women in the First Trimester in Rural Yunnan Province, China. Journal of Kunming Medical University, 2018, 39(06): 39-43.
    [11] Lu Xiao Ning , Zhang Hong Yun , Qian Hong , Lv Song Qin , Tian Yuan , Zhu Min , Zhao Yao . Value of Colposcopy in the Screening of High-grade Cervical Lesions in the Women with HIV Infection. Journal of Kunming Medical University, 2018, 39(07): 41-46.
    [12] Cao Yun . Prevention and Treatment of Intraoperative Hypotension with Combined Spinal-epidural Anesthesia for Cesarean Section. Journal of Kunming Medical University,
    [13] Ma Xiang . The Application of Temporary Balloon Occlusion of the Abdominal Aorta in High-order Position Sacral Tumor Surgical Operation. Journal of Kunming Medical University,
    [14] Sun Heng . . Journal of Kunming Medical University,
    [15] Jin Zhi Xian . . Journal of Kunming Medical University,
    [16] Zhang Yue Ping . . Journal of Kunming Medical University,
    [17] Shi Hui Ping . . Journal of Kunming Medical University,
    [18] . . Journal of Kunming Medical University,
    [19] . . Journal of Kunming Medical University,
    [20] Niu Hua Tao . . Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(3)

    Article Metrics

    Article views (3357) PDF downloads(16) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return