Disease Distribution Pattern Among HIV/AIDS Inpatients in Kunming from 2012 to 2020

Bo TIAN; Jun LIU; Li-hua ZHANG; Rong HE; Shan-qun GU; Chong-xi LI

doi:10.12259/j.issn.2095-610X.S20210827

Volume 42 Issue 8

Aug. 2021

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Bo TIAN, Jun LIU, Li-hua ZHANG, Rong HE, Shan-qun GU, Chong-xi LI. Disease Distribution Pattern Among HIV/AIDS Inpatients in Kunming from 2012 to 2020[J]. Journal of Kunming Medical University, 2021, 42(8): 152-157. doi: 10.12259/j.issn.2095-610X.S20210827

Citation:

Bo TIAN, Jun LIU, Li-hua ZHANG, Rong HE, Shan-qun GU, Chong-xi LI. Disease Distribution Pattern Among HIV/AIDS Inpatients in Kunming from 2012 to 2020[J]. Journal of Kunming Medical University, 2021, 42(8): 152-157. doi: 10.12259/j.issn.2095-610X.S20210827

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Disease Distribution Pattern Among HIV/AIDS Inpatients in Kunming from 2012 to 2020

doi: 10.12259/j.issn.2095-610X.S20210827

Dept. of Infection，The 3rd People’s Hospital of Kunming，Kunming Yunnan 650041，China

Received Date: 2021-06-08
Available Online: 2021-08-04
Publish Date: 2021-08-04

Abstract

Abstract

Objective To investigate the incidence and trends of opportunistic infections in hospitalized patients with HIV/AIDS in Kunming. Methods The data of 7756 inpatients were retrospective analyzed in the third people’ s hospital of Kunming from 2012 to 2020. The number of inpatients and their demographic data of each year were compared. Chi-square test was used to analyze the trend of disease distribution and proportion in each year. From 2012 to 2020, the number of hospitalized patients with HIV/AIDS showed an upward trend. The average hospital stay decreased significantly in 2019 and 2020. The top five co-infections of HIV were bacterial pneumonia （39.01%）, tuberculosis （23.58%）, candidiasis （23.19%）, PCP （8.88%）, CMV （3.83%）. Bacterial pneumonia increased from 2012 to 2016, then decreased from 2017 to 2020. TB prevalence rose from 2012 to 2014 and gradually declined after 2015. Candidiasis showed an increase from 2012 to 2016, and a decrease from 2016 to 2020. PCP increased from 2012 to 2017, and decreased from2017 to 2020. Tuberculosis mainly affected the lungs, followed by lymph nodes, meningeal and pleura. The incidence of liver disease is the highest among non-HIV related diseases （34.39%）, including HCV （22.54%）, HBV （5%）, drug-induced liver injury （4.47%）, fatty liver （1.48%）, alcoholic hepatitis （0.67%）, autoimmune liver disease （0.16%）. Liver disease showed an upward trend from 2012 to 2014, and decreased significantly from 2015 to 2019, then increased in 2020 （P < 0.001）. The incidence of cardiovascular disease is increasing by year （P < 0.001）, other disease showed a slow rise. Conclusion Number of HIV/AIDS patients increases in hospital admissions, the common diseases are bacterial pheumonia, tuberculosis, candidiasis, PCP. Opportunistic infections are mostly on the decline, non-HIV related diseases are on the rise.
- HIV/AIDS,
- Opportunistic infections,
- Disease distribution pattern,
- Dynamic change

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References(16)

References

[1]	UNAIDS. Global AIDS update 2016[EB/OL]. [2019-01-31]. http://www.unaids.org/en/resources/documents/2016/Global-AIDS-up-date-2016.
[2]	O’Connell S,Enkelmann J,Sadlier C,et al. Late HIV presentation-missed opportunities and factors associated with a changing pattern over time[J]. Int J STD AIDS,2017,28(8):814-821. doi: 10.1177/0956462416674093
[3]	Mocroft A,Lundgren J D,Sabin M L,et al. Risk factors and out-comes for late presentation for HIV-positive persons in Europe:resuls from the collaboration of observational HIV epidemiological research Europe study (COHERE)[J]. PloS Med,2013,10(9):e1001510. doi: 10.1371/journal.pmed.1001510
[4]	刘恒丽,李侠,杨欣平,等. 云南省2992例HIV/AIDS住院患者临床特征分析[J]. 中国皮肤性病学杂志,2021,18(5):525-530.
[5]	Yin G W,Guo Y,Jin B. Expressions of NDRG1,VEGF and Ki-67 in condyloma acuminatum[J]. Journal of Biological Regulators and Homeostatic Agents,2016,30(3):773-776.
[6]	Sezgin E,Van Natta M L,Thorne J E,et al. Secular trends in opportunistic infections,cancers,and mortality in patients with AIDS during the era of modern combination antiretroviral therapy[J]. HIV Med,2018,19(6):411-419. doi: 10.1111/hiv.12609
[7]	Vitoria M,Vella S,Ford N. Scaling up antiretroviral therapy in resource-limited settings:Adapting guidance to meet the challenges[J]. Curr Opon HIV AIDS,2013,8(1):12-18. doi: 10.1097/COH.0b013e32835b8123
[8]	何盛华,周锐锋,刘大凤,等. 四川地区1465例艾滋病患者机会性感染分析[J]. 重庆医学,2014,43(5):592,593,596.
[9]	孙燕,陈昭云,赵清霞,等. 河南省2009年至2016年不同时期艾滋病患者合并机会性感染状况比较分析[J]. 中华传染病杂志,2018,36(11):678-680. doi: 10.3760/cma.j.issn.1000-6680.2018.11.008
[10]	韦林华、张彤、吴锋耀,等. HAART时代HIV/AIDS住院病人机会性感染疾病谱分析[J]. 中国艾滋病性病,2018,24(5):454-457.
[11]	Rubaihayo J,Tumwesigye N M,Konde-Lule J,et al. Frequency and distribution patterns of opportunistic infections associated with HIV / AIDS in uganda[J]. BMC Res Notes,2016,9(1):501. doi: 10.1186/s13104-016-2317-7
[12]	Reddy SG,Ali SY,Khalidi A,et al. Study of infections among human immunodeficiency virus acquired immunodeficiency syndrome patients in shadan hospital,telangana,india[J]. Indian J Sex Transm Dis AIDS,2016,37(2):147-150. doi: 10.4103/0253-7184.192122
[13]	Ford N,Shubber Z,Meintjes G,et al. Causes of hospital admission among people living with HIV wordwide:A systematic review and meta-analysis[J]. Lancet HIV,2015,2(10):e438-e444. doi: 10.1016/S2352-3018(15)00137-X
[14]	Gao L,Zhou F,Li X,et al. HIV/TB co-infection in Mainland of China: A meta-analysis[J]. PloS One,2010,5(5):e10736. doi: 10.1371/journal.pone.0010736
[15]	沈佳胤,卢洪洲. 艾滋病合并结核病的防治研究进展[J]. 中国艾滋病性病,2015,21(6):543-546.
[16]	田波,何利平,刘俊,等. HIV合并HBV/HCV病人抗病毒治疗五年疗效及生存状况分析[J]. 中国艾滋病性病,2020,26(7):26-29.

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