The Application of Atropine in General Anaesthesia of Retaining Spontaneous Breathing for Painless Fiberoptic Bronchoscopy

Guang-shun LIU; Xu-dong XIANG; Zhi-yong LV; Min ZHOU; Ya-hong WANG

doi:10.12259/j.issn.2095-610X.S20210912

Volume 42 Issue 9

Sep. 2021

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Guang-shun LIU, Xu-dong XIANG, Zhi-yong LV, Min ZHOU, Ya-hong WANG. The Application of Atropine in General Anaesthesia of Retaining Spontaneous Breathing for Painless Fiberoptic Bronchoscopy[J]. Journal of Kunming Medical University, 2021, 42(9): 71-75. doi: 10.12259/j.issn.2095-610X.S20210912

Citation:

Guang-shun LIU, Xu-dong XIANG, Zhi-yong LV, Min ZHOU, Ya-hong WANG. The Application of Atropine in General Anaesthesia of Retaining Spontaneous Breathing for Painless Fiberoptic Bronchoscopy[J]. Journal of Kunming Medical University, 2021, 42(9): 71-75. doi: 10.12259/j.issn.2095-610X.S20210912

Citation:

Guang-shun LIU, Xu-dong XIANG, Zhi-yong LV, Min ZHOU, Ya-hong WANG. The Application of Atropine in General Anaesthesia of Retaining Spontaneous Breathing for Painless Fiberoptic Bronchoscopy[J]. Journal of Kunming Medical University, 2021, 42(9): 71-75. doi: 10.12259/j.issn.2095-610X.S20210912

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The Application of Atropine in General Anaesthesia of Retaining Spontaneous Breathing for Painless Fiberoptic Bronchoscopy

doi: 10.12259/j.issn.2095-610X.S20210912

1.
Dept. of Anesthesiology
2.
Dept. of Thoracic Surgery，The Third Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650118，China

Received Date: 2021-07-22
Publish Date: 2021-09-25

Abstract

Abstract

Objective To study the role of atropine in spontaneous breathing painless fiberoptic bronchoscopy. Methods Forty cases of patients scheduled for receivepainless fiberoptic bronchoscopy were randomly divided into 2 groups, with 20 cases in each group.The patients in the control group （group C） were gven the intravenous anesthesia with sufentanil 0.1 μg/kg, dexmedetomidine 0.2 μg/kg, propofol 1 mg/kg, remifentanil 0.2 μg/kg, propofol 1 mg/kg, then endotracheal fiberoptic bronchoscopy were conducted cooperating with the endotracheal surface anesthesia.An extra propofol 0.4 mg/kg was given when choking cough or body moving occurred.The patients in the observation group （group S） were given atropine 0.006 mg/kg intravenous injection, the subsequent processing was the same as for group C. The changes of vital signs at different points during the perioperative period, the time of operation, anesthesia recovery and leaving operation room, the excellent and good rate for anesthesia, the number of cases of propofol supplementation and use of vasoactive drugs, the incidence of intraoperative respiratory adverse events and postoperative adverse events were observed and compared between the two groups. Results The levels of HR, MAP and SpO₂ had no significant different between the two groups on T₁ （P > 0.05）, those of group S were significantly higher than group C on T ₂ （P < 0.05）, the levels of HR and MAP on T ₂ were significantly lower than those on T₁ in group C （P < 0.05）, the rate of excellent and good of anesthesia of group S was significantly higher than that of group C （ P < 0.05）, the time of anesthesia recovery and leaving the operation room of group S were significantly lower than that of group C （ P < 0.01）, the number of cases of intraoperative propofol supplementation and use of vasoactive drugs of group S were significantly lower than those of group C （ P < 0.05）, the incidence of intraoperative respiratory adverse events of group S was significantly lower than that of group C （ P < 0.05）. Conclusion Atropine can improve the safety of the anesthesia of preserving spontaneous breathing for painless fiberoptic bronchoscopy.
- Atropine,
- Spontaneous breathing,
- Fiberoptic bronchoscope,
- Painless,
- Application

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References(17)

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