The Characteristics of Echocardiography in Acute Incomplete Kawasaki Disease among Infants and Young Children in Yunnan Province

Li-zheng WEI; Jie-qing MIN; Jin-run TIAN; Yan-jie CAO; Peng PAN; Peng WANG; Yun-juan YANG; Yun-jiao LUO

doi:10.12259/j.issn.2095-610X.S20210923

Volume 42 Issue 9

Sep. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(9): 114-118

Li-zheng WEI, Jie-qing MIN, Jin-run TIAN, Yan-jie CAO, Peng PAN, Peng WANG, Yun-juan YANG, Yun-jiao LUO. The Characteristics of Echocardiography in Acute Incomplete Kawasaki Disease among Infants and Young Children in Yunnan Province[J]. Journal of Kunming Medical University, 2021, 42(9): 114-118. doi: 10.12259/j.issn.2095-610X.S20210923

Citation:

Li-zheng WEI, Jie-qing MIN, Jin-run TIAN, Yan-jie CAO, Peng PAN, Peng WANG, Yun-juan YANG, Yun-jiao LUO. The Characteristics of Echocardiography in Acute Incomplete Kawasaki Disease among Infants and Young Children in Yunnan Province[J]. Journal of Kunming Medical University, 2021, 42(9): 114-118. doi: 10.12259/j.issn.2095-610X.S20210923

Citation:

Li-zheng WEI, Jie-qing MIN, Jin-run TIAN, Yan-jie CAO, Peng PAN, Peng WANG, Yun-juan YANG, Yun-jiao LUO. The Characteristics of Echocardiography in Acute Incomplete Kawasaki Disease among Infants and Young Children in Yunnan Province[J]. Journal of Kunming Medical University, 2021, 42(9): 114-118. doi: 10.12259/j.issn.2095-610X.S20210923

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The Characteristics of Echocardiography in Acute Incomplete Kawasaki Disease among Infants and Young Children in Yunnan Province

doi: 10.12259/j.issn.2095-610X.S20210923

1.
Dept.of Cardiac Function，Kunming Childern’s Hospital，Kunming Yunnan 650103
2.
Yunnan Center for Disease Control and Prevention，Kunming Yunnan 650011
3.
Dept. of Infectious Diseases，Kunming Children’s Hospital，Kunming Yunnan 650103，China

Received Date: 2021-07-11
Available Online: 2021-09-15
Publish Date: 2021-09-30

Abstract

Abstract

Objective To the echocardiography characteristics and the risk factors of coronary artery dilation among the infants with incomplete kawasaki disease （IKD） in Yunnan Province. Methoded A total of 291 children with Kawasaki disease under 3 years were studied retrospectively, All of them were treated in the Kunming Childrens’ Hospital from April 2017 to April 2019, including 113 children with IKD and 179 children with complete kawasaki disease （CKD）, All the children were examined by echocardiography, and the coronary aortic diameter, Z value and the peak diastolic flow velocity （PDV）, mean diastolic flow velocity （MDV） of the two groups were compared. In a way to whether the patient had the coronary artery dilation, risk factors on the coronary artery dilation by single factor and multi factors were analyzed with the logistic regression. Resulted 1. The IKD group with the coronary artery injury was more serious than that in the CKD group （P < 0.05）, and the younger the child, the more severe with coronary artery; There were no significant differences of PDV and MDV between the two groups with the coronary artery dilation （P > 0.05）. The difference in the Z value of the coronary artery diameter between the two groups was statistically significant （P < 0.05） ; 2. The potential risk factors for atypical KD coronary artery dilation were analyzed with the logistic regression. Multivariate linear regression analysis showed that: duration of fever ≥5 d （OR = 1.408, P = 0.006）, C-reactive protein level ≥0.8 ng/L （OR = 1.396, P = 0.003）, white blood cell count ≥20×109/L （OR = 1.382, P = 0.002）, serum albumin ≥135 g/L （OR = 1.867, P = 0.004） were the independent risk factors for the coronary artery dilation, P < 0.05. Conclusion Incomplete Kawasaki disease has a high incidence in infants and young children, and the clinical manifestations are not obvious, which can easily lead to the delay in the disease. It should be taken attention of clinicians. And the younger the age, the worse the coronary artery damage, and echocardiography has the great significance for the early diagnosis of coronary artery disease, Z value can objectively evaluate the damage of coronary artery and the evaluation of the effect after the treatment.
- Yunnan Province,
- Infants and young children,
- IKD,
- Acute phase,
- Echocardiography

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References(15)

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