Curative Effect of Combined Hemihepatectomy and Perihilar Hepatectomy in Treatment of Hilar Cholangiocarcinoma

Liu-zheng LI; Shun LU; Shi-rong ZHANG; Lei-sheng XU; Hai-rong ZHAO; Jia-wei FENG; Xue-chan GAO; Tong WU

doi:10.12259/j.issn.2095-610X.S20211014

Volume 42 Issue 10

Oct. 2021

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Zhang Xue Qin , Xu Xiao Lin . Clinical Effect of Lansoprazole on Patients with Gastroesophageal Reflux and the Esophageal Dynamics[J]. Journal of Kunming Medical University, 2017, 38(04): 76-79.

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Liu-zheng LI, Shun LU, Shi-rong ZHANG, Lei-sheng XU, Hai-rong ZHAO, Jia-wei FENG, Xue-chan GAO, Tong WU. Curative Effect of Combined Hemihepatectomy and Perihilar Hepatectomy in Treatment of Hilar Cholangiocarcinoma[J]. Journal of Kunming Medical University, 2021, 42(10): 121-126. doi: 10.12259/j.issn.2095-610X.S20211014

Zhang Xue Qin , Xu Xiao Lin . Clinical Effect of Lansoprazole on Patients with Gastroesophageal Reflux and the Esophageal Dynamics[J]. Journal of Kunming Medical University, 2017, 38(04): 76-79.

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Curative Effect of Combined Hemihepatectomy and Perihilar Hepatectomy in Treatment of Hilar Cholangiocarcinoma

doi: 10.12259/j.issn.2095-610X.S20211014

Dept. of Hepatobiliary Surgery，Lincang People’s Hospital，Lincang Yunnan 677000，China

Received Date: 2021-07-24
Available Online: 2021-10-29
Publish Date: 2021-10-30

Abstract

Abstract

Objective To summarize the curative effect of different surgical resection methods for hilar cholangiocarcinoma （HCCA）. Methods The clinical data of 52 patients with HCCA who underwent surgery in Lincang people's Hospital from January 2015 to December 2020 were retrospectively analyzed. Among them, 36 cases were treated with hemihepatectomy/extended hemihepatectomy + total caudate lobectomy （combined hemihepatectomy group）, 16 cases of hilar/perihilar region + total caudate lobectomy （perihilar resection group）, The preoperative data, intraoperative blood loss, operation time, positive rate of tumor margin, postoperative hospital stay, CA19-9 value at 3 months after operation, and 1, 3-year survival rate of the two groups were compared and analyzed. Results The indexes of the combined hemihepatectomy group and perihepatectomy group were as following: the intraoperative blood loss [（705.5±54.3） mL vs （809.9±61.4） mL], the operation time [（240.4 ± 22.5） min vs （358.1 ± 31.1） min], the positive rate of tumor resection margin （8.3% vs 18.8%）, the negative rate of CA19-9 3 months after operation （88.2% vs 73.3%）, and the 1-year survival rate （58.8% vs 40.0%）. The difference was statistically significant between the two groups （P < 0.05）. Conclusion Combined hemihepatectomy and perihilar hepatectomy are effective surgical methods for HCCA, But the former has higher R0 resection rate and short-term survival rate.
- Keywords hilar tumor,
- Hepatectomy/method,
- Prognosis

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References

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