Volume 42 Issue 12
Dec.  2021
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Shi-yu LI, Shi-gang DU, Ling ZHAO, Lu YANG, Pei-qi CHEN, Yu-ru DAI, Ting-yu KE. Correlation between TIR and Diabetic Albuminuria[J]. Journal of Kunming Medical University, 2021, 42(12): 23-27. doi: 10.12259/j.issn.2095-610X.S20211214
Citation: Shi-yu LI, Shi-gang DU, Ling ZHAO, Lu YANG, Pei-qi CHEN, Yu-ru DAI, Ting-yu KE. Correlation between TIR and Diabetic Albuminuria[J]. Journal of Kunming Medical University, 2021, 42(12): 23-27. doi: 10.12259/j.issn.2095-610X.S20211214

Correlation between TIR and Diabetic Albuminuria

doi: 10.12259/j.issn.2095-610X.S20211214
  • Received Date: 2021-09-16
    Available Online: 2021-12-01
  • Publish Date: 2021-12-15
  •   Objective   To explore the correlation between time in range (TIR) and diabetic albuminuria in patients with type 2 diabetes.   Methods  120 patients aged 30 to 65 years and diagnosed with type 2 diabetes within 10 years were enrolled. Continuous Sugar Monitoring System (CGMS) was used to observe TIR of the patients. With TIR 30%, 50% and 70% as cut-off points, 120 patients were divided into 4 groups with 30 cases in each group: Study group 1: TIR > 70%, Study group 2: 50% < TIR≤70%, Study group 3: 30% < TIR≤50%, study group 4: TIR≤30%. The general characteristics, laboratory data, blood glucose monitoring data and the correlation between TIR and diabetic proteinuria of the 4 groups were analyzed.   Results  There were differences in LDL-C, HbA1c, UAER, and urine microalbumin among the 4 groups (P < 0.05), while there were no significant differences in age, gender, BMI, blood pressure, blood lipids, and renal function among the 4 groups. TIR was found to be an independent risk factor for diabetic proteinuria after adjusting for general information such as age and blood pressure, using Logistic regression analysis.   Conclusion   TIR is closely related to the occurrence and degree of diabetic albuminuria.
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