Etiology，Diagnosis and Treatment of 84 Children with Central Airway Stenosis

Song-tao BIN; Cheng-qing WU; Li TAN; Rui HAO; Ming LI; Xia ZHANG

doi:10.12259/j.issn.2095-610X.S20211231

Volume 42 Issue 12

Dec. 2021

Turn off MathJax

Article Contents

Article Navigation > Journal of Kunming Medical University > 2021 > 42(12): 123-128

Song-tao BIN, Cheng-qing WU, Li TAN, Rui HAO, Ming LI, Xia ZHANG. Etiology，Diagnosis and Treatment of 84 Children with Central Airway Stenosis[J]. Journal of Kunming Medical University, 2021, 42(12): 123-128. doi: 10.12259/j.issn.2095-610X.S20211231

Citation:

Song-tao BIN, Cheng-qing WU, Li TAN, Rui HAO, Ming LI, Xia ZHANG. Etiology，Diagnosis and Treatment of 84 Children with Central Airway Stenosis[J]. Journal of Kunming Medical University, 2021, 42(12): 123-128. doi: 10.12259/j.issn.2095-610X.S20211231

Citation:

PDF( 707 KB)

Etiology，Diagnosis and Treatment of 84 Children with Central Airway Stenosis

doi: 10.12259/j.issn.2095-610X.S20211231

Dept. of Respiratory Medicine，Kunming Children’s Hospital/Children’s Hospital of Kunming Medical University，Kunming Yunnan 650011，China

Received Date: 2021-10-09
Publish Date: 2021-12-25

Abstract

Abstract

Objective To analyze the etiology and morphological classification of children with central airway stenosis, and to explore the diagnosis and treatment methods. Methods Clinical data of 84 children with central airway stenosis hospitalized from August 2017 to August 2020 were retrospectively collected, including 54 males and 30 females; aged 20d to 14 years, and there are 64 infants （76%, 64/84）. Through CT and electronic bronchoscopy, the etiology and morphological characteristics of the children's central airway stenosis were determined, and the treatment based on electronic bronchoscopy was developed. Results （1） Majority of them were structural stenosis （88.1%, 74/84）, and a few were dynamic stenosis （11.9%, 10/84）. （2） The most common stenosis was left and right main bronchial stenosis （54.8%, 46/84）, followed by subglottic stenosis （23.8%, 20/84）, and carina stenosis （2.4%, 2/84）（3） 76% to 90% stenosis of was the most common （54.8%, 46/84）. （4） Stenosis of 1-3cm was the most common （57.1%, 48/84）. 16 of the 84 cases received follow-up observation without intervention treatment, and their conditions were stable during follow-up observation. 50 patients received electronic bronchoscope intervention therapy, the treatment was effective. Conclusion Central airway stenosis can be reported in children of all ages, and its etiology and morphological classification can be basically determined by CT and electronic bronchoscopy examination. The central airway stenosis in children was mainly structural and benign. Interventional therapy via electronic bronchoscope is the main treatment for central airway stenosis in children.
- Central airway,
- Stenosis,
- Treatment,
- Electronic bronchoscope,
- Children

FullText(HTML)

References(24)

References

[1]	Freitag L,Ernst A,Unger M. A proposed classification sys- tem of central airway stenosis[J]. Eur Respir J,2007,30(6):7-12.
[2]	DeLorimier A A,Harrison M R,Hardy K,et al. Tracheobronchial obstructions in infants and children Experience with 45 cases[J]. Ann Surg,1990,212(3):277-289. doi: 10.1097/00000658-199009000-00006
[3]	苏柱泉,魏晓群,钟长镐,等. 良性气管狭窄158例病因及介入治疗疗效分析[J]. 中华结核和呼吸杂志,2013,36(9):651-654. doi: 10.3760/cma.j.issn.1001-0939.2013.09.004
[4]	Freitag L,Ernst A,Unger M,et al. A proposed classification system of central airway stenosis[J]. Eur Respir J,2007,30(1):7-12. doi: 10.1183/09031936.00132804
[5]	中华医学会呼吸病学分会. 良性中心气道狭窄经支气管镜介入诊治专家共识[J]. 中华结核和呼吸杂志,2017,40(6):408-418. doi: 10.3760/cma.j.issn.1001-0939.2017.06.004
[6]	孟晨,刘玺诚. 中国儿科可弯曲支气管镜术指南(2018版)[J]. 中华实用儿科临床杂志,2018,33(3):983-989.
[7]	张渊博, 苏苗赏, 李昌崇. 儿童气管支气管软化症的临床研究进展[ J ]. 国际呼吸杂志, 2016, 36（20）: 1596-1598
[8]	王婷, 张杰, 王娟, 等. 气管插管或气管切开后气管狭窄的内镜诊疗 [ J ] . 中华结核和呼吸杂志, 2015, 38（8）: 627-629
[9]	海波,徐志伟,苏肇伉,等. 肺动脉吊索的诊断和治疗[J]. 中华胸心血管外科杂志,2005,21(6):334-337. doi: 10.3760/cma.j.issn.1001-4497.2005.06.005
[10]	刘鹏、张建良, 刘建滨, 等. 多排螺旋CT气道、血管三维重建评估先天性左肺动脉吊带患儿气道狭窄的作用探讨[ J ]. 临床小儿外科杂志, 2018, 17（1）: 47-50
[11]	Alvarez Maldonado P,Pena J,Criales Cortés J L,et al. Benign tracheal stenosis:A case series analysis[J]. J Bronchology Interv Pulmonol,2009,16(4):254-260. doi: 10.1097/LBR.0b013e3181b61579
[12]	Finkelstein S E, Summers R M, Nguyen D M, et al. Virtual bronchoscopy for evaluation of airway disease [ J ] . Thorac Surg Clin, 2004, 14 （1）: 79-86
[13]	Kleiss I J,Verhagen A F,Honings J. Tracheal surgery forbenign tracheal stenosis:Our experience in sixty three patients[J]. Clin Otolaryngol,2013,38(4):343-347. doi: 10.1111/coa.12131
[14]	Dalar L, Karasulu L, Abul Y. Bronchoscopic Treatment in the management of benign tracheal stenosis: Choices for simple and complex tracheal stenosis[ J] . Ann Thorac Surg, 2016, 101 （4） : 1310-1317
[15]	丽洁,黄英,李渠北,等. 儿童疑难支气管结核12例[J]. 中华实用儿科临床杂志,2013,28(4):268-270. doi: 10.3760/cma.j.issn.2095-428X.2013.04.010
[16]	高鸿,王洪武,周云芝. 气管和支气管乳头状瘤分析[J]. 中国内镜杂志,2018,25(8):10-14.
[17]	段效军,黄建宝,王江平,等. 经纤维支气管镜介入治疗儿童获得性声门下狭窄[J]. 临床小儿外科杂志,2020,19(7):631-635.
[18]	Soong W J. Pediatric interventional flexible bronchoscopy [J]. Pediatr Respirol Crit Care Med, 2018, 2（期?）: 38-44. DOI: 10. 4103 / prcm. prcm_12_18. doi: 10.4103/prcm.prcm_12_18 Soong W J. Pediatric interventional flexible bronchoscopy[J]. Pediatr Respirol Crit Care Med,2018,2:38-44. doi: 10.4103/prcm.prcm_12_18
[19]	Cuestas G,Rodríguez V,Doormann F,et al. Endoscopic treatment of acquired subglottic stenosis in children:Pre- dictors of success[J]. Arch Argent Pediatr,2018,116(6):422-425. doi: 10.5546/aap.2018.eng.422
[20]	丁卫民,王敬萍,傅瑜,等. 球囊扩张术治疗支气管结核气道狭窄的临床价值[J]. 中华结核和呼吸杂志,2010,33(7):510-514. doi: 10.3760/cma.j.issn.1001-0939.2010.07.008
[21]	Zhang J,Wang T,Wang J,et al. Effect of three interventional bronchoscopic methods on tracheal stenosis and the formation of granulation tissues in dogs[J]. Chin Med J (Engl),2010,123(5):621-627.
[22]	焦安夏. 气道消融术在现代儿科介入呼吸病学的应用[J]. 中国实用儿科杂志,2019,34(6):482-485.
[23]	宾松涛,李明,谭力,等. 探讨球囊导管扩张术在儿科呼吸介入中的应用[J]. 临床肺科杂志,2020,25(5):802-804. doi: 10.3969/j.issn.1009-6663.2020.05.035
[24]	焦安夏, 饶小春, 马渝燕. 儿童良性中央气道狭窄133例病因分析[J]. 山西医科大学学报,2010,41(6):559-562.

Relative Articles(20)

Relative Articles

[1]	Yanjuan CHEN, Wanrong LUO, Ruixue MA, Yilin DAI, Guixian LI, Yunfen TIAN. Clinical Analysis of the Spectrum of Upper Gastrointestinal Diseases in 424 Cases of Children in A Tertiary Hospital in Kunming. Journal of Kunming Medical University, 2024, 45(12): 1-6.
[2]	Yilin DAI, Yunfen TIAN. Application and Research Progress of Drugs in Intestinal Preparation before Colonoscopy in Children. Journal of Kunming Medical University, 2024, 45(10): 155-159. doi: 10.12259/j.issn.2095-610X.S20241024
[3]	Wei HU, Jinnan LI, Wei YANG, Li SU, Zhuo YU, Zhisong CHEN. Interventional Treatment of Muscular Ventricular Septal Defect in Children. Journal of Kunming Medical University, 2024, 45(3): 48-53. doi: 10.12259/j.issn.2095-610X.S20240307
[4]	Ji WANG, Songtao BIN, Li TAN. Study on the Efficacy of Acetylcysteine in Severe Pneumonia in Children under Electronic Bronchoscopy. Journal of Kunming Medical University, 2024, 45(6): 113-119. doi: 10.12259/j.issn.2095-610X.S20240615
[5]	Baochuan HUANG, Wuquan LI, Yi TANG. An Epidemiological Analysis of 1500 Pediatric BurnsPatients at the Burn Center in Yunnan. Journal of Kunming Medical University, 2024, 45(10): 1-9.
[6]	Xixiong SU, Wei XU, Liqi XU, Qin YANG, Yunli YANG. Effects of Percutaneous Transluminal Angioplasty Plus Open Operation in Hemodialysis Patients with Type I and II Upper Limb Arteriovenous Fistula Stenosis. Journal of Kunming Medical University, 2022, 43(6): 52-55. doi: 10.12259/j.issn.2095-610X.S20220626
[7]	Li TAN, Ming LI, Yu-xing SUN, Zhen ZHANG, Zheng-yan GAN. Molecular Epidemiology of Human Rhinovirus in 2 260 Children with Acute Lower Respiratory Tract Infection. Journal of Kunming Medical University, 2020, 41(12): 119-122. doi: 10.12259/j.issn.2095-610X.S20201233
[8]	Yang Jun Jun , Hu Xi Chi , Yan Zi He . . Journal of Kunming Medical University, 2017, 38(03): 119-122.
[9]	Tang Wen Guang . . Journal of Kunming Medical University,
[10]	Zhou Ju Lan . . Journal of Kunming Medical University,
[11]	Cao Xiao Jin . . Journal of Kunming Medical University,
[12]	Bi Hong . . Journal of Kunming Medical University,
[13]	Zhang Meng Si . . Journal of Kunming Medical University,
[14]	He Cheng Lu . . Journal of Kunming Medical University,
[15]	Jin Zhi Xian . . Journal of Kunming Medical University,
[16]	Ma Yun Bing . . Journal of Kunming Medical University,
[17]	Zhan Hui . . Journal of Kunming Medical University,
[18]	. The Diagnosis Value of Electronic Bronchoscope to Lung Cancer. Journal of Kunming Medical University,
[19]	. . Journal of Kunming Medical University,
[20]	Deng Yan . . Journal of Kunming Medical University,