Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection

Ying HUANG; Xiang LI; Shan JIANG; Bing LIU; Yan-ling ZHANG; Yang LI; Hua HE; Yan WU; Yun LUO; Jun XU

doi:10.12259/j.issn.2095-610X.S20211232

Volume 42 Issue 12

Dec. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(12): 129-134

Ying HUANG, Xiang LI, Shan JIANG, Bing LIU, Yan-ling ZHANG, Yang LI, Hua HE, Yan WU, Yun LUO, Jun XU. Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection[J]. Journal of Kunming Medical University, 2021, 42(12): 129-134. doi: 10.12259/j.issn.2095-610X.S20211232

Citation:

Ying HUANG, Xiang LI, Shan JIANG, Bing LIU, Yan-ling ZHANG, Yang LI, Hua HE, Yan WU, Yun LUO, Jun XU. Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection[J]. Journal of Kunming Medical University, 2021, 42(12): 129-134. doi: 10.12259/j.issn.2095-610X.S20211232

Citation:

Ying HUANG, Xiang LI, Shan JIANG, Bing LIU, Yan-ling ZHANG, Yang LI, Hua HE, Yan WU, Yun LUO, Jun XU. Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection[J]. Journal of Kunming Medical University, 2021, 42(12): 129-134. doi: 10.12259/j.issn.2095-610X.S20211232

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Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection

doi: 10.12259/j.issn.2095-610X.S20211232

1.
Dept. of Infectious Diseases
2.
Dept. of Radiology，Kunming Third People’s Hospital，Kunming Yunnan 650041
3.
School of Public Health， Dali University，Dali Yunnan 671000，China

Received Date: 2021-09-13
Available Online: 2021-11-17
Publish Date: 2021-12-15

Abstract

Abstract

Objective To investigate the correlation between chest CT scan and laboratory indicators in 2019-nCoV infected patients, and to provide reference for early diagnosis and treatment. Methods Retrospective analysis was performed on 2019-nCoV infected patients admitted to the Third People’s Hospital of Kunming from February to March 2020. Patients were divided into abnormal chest CT group and normal chest CT group. Correlation analysis was conducted on CT data and laboratory related indicators. Results The age of 9 patients with 2019-nCoV infection was positively correlated with the size of whole lung consolidation shadow and ground glass density shadow （r = 0.34, r = 0.48, P < 0.05）, and age was positively correlated with the size of whole lung lesion （r = 0.40, P < 0.05）. Pneumonia accounted for 64.1%, among which double lung disease accounted for 80.00%, unilateral disease accounted for 20.00%; There were differences in eosinophil count, CRP, CD8⁺ count and R-glutamylaminotransferase increase in lung CT with or without abnormality （P < 0.05）. The size of lung lesion was negatively correlated with lymphocyte count, eosinophil count, CD8⁺ and CD3⁺ count, and positively correlated with CRP and GGT. Conclusion In 2019-nCoV patients, bilateral lung lesions are common. The older the age, the more lung lesions; The lower the number of lymphocytes, the higher the number of CD8⁺ and CD3⁺, the higher the CRP and GGT, the more lung lesions, which can be used as an early warning indicator of pneumonia and severe disease.
- 2019-nCoV infected patients,
- Chest CT,
- Laboratory related indicators,
- Correlation

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References(17)

References

[1]	国家卫生健康委员会. 国家中医药管理局. 新型冠状病毒肺炎诊疗方案试行第7版[EB/0T]. （2020-03-03）[2020-08-07]. http: //www.nhc.Govcn/yzygj/s7653p/202003/46c9294a7dfe4cef80dc7f5912eb1989.shtml.
[2]	中华医学会放射学分会传染病学组,中国医师协会放射医师分会感染影像专委会,中国研究型医院学会感染与炎症放射学分会,等. 新型冠状病毒感染的肺炎影像学诊断指南(2020第1版)[J]. 医学新知,2020,30(1):22-34. doi: 10.12173/j.issn.1004-5511.2020.01.07
[3]	中华医学会放射学分会. 新型冠状病毒感染的肺炎的放射学诊断[J]. 中华放射学杂志,2020,54(4):001. doi: 10.3760/cma.j.issn.1005-1201.2020.0001
[4]	张楠,徐勋华,李宇,等. 胸部CT在新型冠状病毒肺炎患者诊断及治疗中的应用[J]. 心肺血管病杂志,2020,39(2):127-133.
[5]	周灵,刘辉国. 新型冠状病毒肺炎患者的早期识别和病情评估[J]. 中华结核和呼吸杂志,2020,43(3):167-170. doi: 10.3760/cma.j.issn.1001-0939.2020.03.003
[6]	Kato S,Asano N,Miyata-Takata T,etal. T-cell receptor(TCR)phenotype of nodal epstein-barr virus(EBV)-positive cytotoxic T-cell lymphoma(CTL);Aclinicopathologic study of 39 cases[J]. Am J Surg Pathol,2015,39(4):462-471. doi: 10.1097/PAS.0000000000000323
[7]	樊菡,王莉,王晓,等. 老年新型冠状病毒肺炎患者的临床特征[J]. 中国老年学杂志,2021,4(41):1414-1417.
[8]	何光武,孙昂. 新型冠状病毒肺炎的影像学诊断[J]. 医学研究杂志,2021,50(1):1-4.
[9]	夏萌,严龙君,熊敏超,等. 湖北省鄂州市 30 例新型冠状病毒肺炎患者胸部 CT 表现分析[J]. 山东医药,2020,60(5):48-50. doi: 10.3969/j.issn.1002-266X.2020.05.011
[10]	汪锴,康嗣如,田荣华,等. 新型冠状病毒肺炎胸部 CT 影像学特征分析[J]. 中国临床医学,2020,27(1):27-31.
[11]	卢亦波,周静如,莫移美,等. 31例新型冠状病毒肺炎临床及CT影像表现初步观察[J]. 新发传染病电子杂志,2020,5(2):79-82. doi: 10.3877/j.issn.2096-2738.2020.02.004
[12]	马培旗,袁玉山,张磊,等. 75例新型冠状病毒肺炎病人首诊CT表现与检验结果分析[J]. 国际医学放射学杂志,2020,43(2):127-130.
[13]	张艳,高锦,徐爱芳,等. 多项炎症感染指标在新型冠状病毒肺炎中的变化及鉴别诊断价值[J]. 浙江医学,2020,42(16):1738-1741. doi: 10.12056/j.issn.1006-2785.2020.42.16.2020-1005
[14]	区静怡, 谭明凯, 陈星, 等. 炎症指标及血常规在新型冠状病毒肺炎患者病程中的水平变化及应用价值[J]. 检验医学与临床, 202, 18（6）: 733-737.
[15]	靳云洲,李明芳,郑胜,等. 新型冠状病毒肺炎患者不同病情状态下淋巴细胞、白细胞介素-6及炎症指标的变化[J]. 实用临床医药杂志,2020,24(6):1-4.
[16]	李璐,李爽,陈煜,等. 新型冠状病毒肺炎合并肝损伤的发生机制[J]. 临床肝胆病杂志,2021,37(1):209-211. doi: 10.3969/j.issn.1001-5256.2021.01.046
[17]	Chai X , Hu L , Zhang Y , et al. Specific ACE2 expression in cholangiocytes may cause liver damage after 2019-nCoV infection[J]. Bio Rxiv, 2020, 4（4）: 1-13. DOI: 10.1101/2020.02.03.931766.

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