Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection

Ying HUANG; Xiang LI; Shan JIANG; Bing LIU; Yan-ling ZHANG; Yang LI; Hua HE; Yan WU; Yun LUO; Jun XU

doi:10.12259/j.issn.2095-610X.S20211232

Volume 42 Issue 12

Dec. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(12): 129-134

Ying HUANG, Xiang LI, Shan JIANG, Bing LIU, Yan-ling ZHANG, Yang LI, Hua HE, Yan WU, Yun LUO, Jun XU. Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection[J]. Journal of Kunming Medical University, 2021, 42(12): 129-134. doi: 10.12259/j.issn.2095-610X.S20211232

Citation:

Ying HUANG, Xiang LI, Shan JIANG, Bing LIU, Yan-ling ZHANG, Yang LI, Hua HE, Yan WU, Yun LUO, Jun XU. Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection[J]. Journal of Kunming Medical University, 2021, 42(12): 129-134. doi: 10.12259/j.issn.2095-610X.S20211232

Citation:

Ying HUANG, Xiang LI, Shan JIANG, Bing LIU, Yan-ling ZHANG, Yang LI, Hua HE, Yan WU, Yun LUO, Jun XU. Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection[J]. Journal of Kunming Medical University, 2021, 42(12): 129-134. doi: 10.12259/j.issn.2095-610X.S20211232

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Correlation Analysis of Chest Imaging and Laboratory Indicators in Patients with 2019-nCoV Infection

doi: 10.12259/j.issn.2095-610X.S20211232

1.
Dept. of Infectious Diseases
2.
Dept. of Radiology，Kunming Third People’s Hospital，Kunming Yunnan 650041
3.
School of Public Health， Dali University，Dali Yunnan 671000，China

Received Date: 2021-09-13
Available Online: 2021-11-17
Publish Date: 2021-12-15

Abstract

Abstract

Objective To investigate the correlation between chest CT scan and laboratory indicators in 2019-nCoV infected patients, and to provide reference for early diagnosis and treatment. Methods Retrospective analysis was performed on 2019-nCoV infected patients admitted to the Third People’s Hospital of Kunming from February to March 2020. Patients were divided into abnormal chest CT group and normal chest CT group. Correlation analysis was conducted on CT data and laboratory related indicators. Results The age of 9 patients with 2019-nCoV infection was positively correlated with the size of whole lung consolidation shadow and ground glass density shadow （r = 0.34, r = 0.48, P < 0.05）, and age was positively correlated with the size of whole lung lesion （r = 0.40, P < 0.05）. Pneumonia accounted for 64.1%, among which double lung disease accounted for 80.00%, unilateral disease accounted for 20.00%; There were differences in eosinophil count, CRP, CD8⁺ count and R-glutamylaminotransferase increase in lung CT with or without abnormality （P < 0.05）. The size of lung lesion was negatively correlated with lymphocyte count, eosinophil count, CD8⁺ and CD3⁺ count, and positively correlated with CRP and GGT. Conclusion In 2019-nCoV patients, bilateral lung lesions are common. The older the age, the more lung lesions; The lower the number of lymphocytes, the higher the number of CD8⁺ and CD3⁺, the higher the CRP and GGT, the more lung lesions, which can be used as an early warning indicator of pneumonia and severe disease.
- 2019-nCoV infected patients,
- Chest CT,
- Laboratory related indicators,
- Correlation

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References(17)

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