The Regularity and Clinical Manifestations of Throat Swab and Fecal Detoxification in New Coronavirus Infected Patients

Ying HUANG; Yun LUO; Yan WU; Bing LIU; Shan JIANG; Hua HE

doi:10.12259/j.issn.2095-610X.S20220112

Volume 43 Issue 1

Jan. 2022

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Ying HUANG, Yun LUO, Yan WU, Bing LIU, Shan JIANG, Hua HE. The Regularity and Clinical Manifestations of Throat Swab and Fecal Detoxification in New Coronavirus Infected Patients[J]. Journal of Kunming Medical University, 2022, 43(1): 96-101. doi: 10.12259/j.issn.2095-610X.S20220112

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The Regularity and Clinical Manifestations of Throat Swab and Fecal Detoxification in New Coronavirus Infected Patients

doi: 10.12259/j.issn.2095-610X.S20220112

Ying HUANG¹,
Yun LUO¹,
Yan WU¹,
Bing LIU²,
Shan JIANG²,
Hua HE^{1
,
,}

1.
Dept. of Infectious Diseases，Kunming Third People’s Hospital，Kunming Yunnan 650041
2.
School of Public Health，Dali University，Dali Yunnan 671000，China

Received Date: 2021-12-18
Available Online: 2021-12-20
Publish Date: 2022-01-15

Abstract

Abstract

Objective To explor the clinical characteristics and detoxification rules of the patients with COVID-19 nucleic acid positive by analyzing their clinical manifestations of throat swabs and fecal, so as to provide the evidence for the clinical diagnosis and treatment. Methods The clinical symptoms, laboratory indexes, and the detoxification of throat swab and faecal in 59 patients with COVID-19 infection admitted to Kunming Third People’s Hospital from February 2020 to December were retrospectively analyzed. Result Fecal positive group: In 7 cases of latent infection, the first pharyngeal swab nucleic acid was positive to symptomatic for 3～8 days （median 4 days）, 5 cases were continuously positive and 2 cases were repeatedly positive; The stool was positive 1～28 days after the pharyngeal swab was positive （median 6 days）. 5 cases were asymptomatic, 2 cases were continuously positive and 2 cases were repeatedly positive; The stool was positive 4～21 days after the pharyngeal swab was positive （median 6 days）. 21 symptomatic patients were positive for pharyngeal swab for 1～21 days （median 5 days）, 8 cases were continuously positive for 4～20 days, and 10 cases were repeatedly positive for 8～26 days; The stool was positive 4～29 days after the pharyngeal swab was positive （median 15 days）. Fecal negative group: In 6 cases of latent infection, pharyngeal swabs were positive to symptomatic for 4～10 days （median 5 days）, 2 cases were continuously positive and 2 cases were repeatedly positive; In 4 asymptomatic patients, pharyngeal swabs were continuously positive in 1 case and repeatedly positive in 1 case; In 16 symptomatic patients, the pharyngeal swab was positive for 1～16 days （median 5.5 days）, 3 cases were continuously positive and 10 cases were repeatedly positive. There was significant difference in the continuous positive time of the pharyngeal swab nucleic acid between the two groups （P < 0.05）, and there was no significant difference in the repeated positive time （P > 0.05）; There was significant difference in CT findings between the two groups （P < 0.05）; There was no significant difference in clinical manifestations, liver function, renal function, myocardial enzymes, blood routine, CRP and T lymphocytes between the two groups （P > 0.05）. Conclusion There is no difference in symptoms and signs, organ function injury and inflammatory indexes between the two groups. The regularity of virus detoxification is not strong, but those who detoxify with pharyngeal swabs and feces last longer than those who detoxify only with pharyngeal swabs, and pneumonia is more common.
- New Coronavirus infection,
- Pharyngeal swab,
- Faeces,
- Viral nucleic acid

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References

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