Studies on the Correlation between Serum Vitamin A, D and Lung Function in Infants with Asthmatic Pneumonia

Linxia LI; Yanhong LI; Jie WU; Lili ZHANG; Xian ZHANG; Song WANG; Juntao ZHANG; Peng YAN

doi:10.12259/j.issn.2095-610X.S20220114

Volume 43 Issue 1

Jan. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(1): 63-66

Linxia LI, Yanhong LI, Jie WU, Lili ZHANG, Xian ZHANG, Song WANG, Juntao ZHANG, Peng YAN. Studies on the Correlation between Serum Vitamin A, D and Lung Function in Infants with Asthmatic Pneumonia[J]. Journal of Kunming Medical University, 2022, 43(1): 63-66. doi: 10.12259/j.issn.2095-610X.S20220114

Citation:

Linxia LI, Yanhong LI, Jie WU, Lili ZHANG, Xian ZHANG, Song WANG, Juntao ZHANG, Peng YAN. Studies on the Correlation between Serum Vitamin A, D and Lung Function in Infants with Asthmatic Pneumonia[J]. Journal of Kunming Medical University, 2022, 43(1): 63-66. doi: 10.12259/j.issn.2095-610X.S20220114

Citation:

Linxia LI, Yanhong LI, Jie WU, Lili ZHANG, Xian ZHANG, Song WANG, Juntao ZHANG, Peng YAN. Studies on the Correlation between Serum Vitamin A, D and Lung Function in Infants with Asthmatic Pneumonia[J]. Journal of Kunming Medical University, 2022, 43(1): 63-66. doi: 10.12259/j.issn.2095-610X.S20220114

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Studies on the Correlation between Serum Vitamin A, D and Lung Function in Infants with Asthmatic Pneumonia

doi: 10.12259/j.issn.2095-610X.S20220114

Dept. of Pediatrics，The 2nd Affliated Hospital of Kunming Medical University， Kunming Yunnan 650101，China

Received Date: 2021-11-28
Available Online: 2021-12-20
Publish Date: 2022-01-15

Abstract

Abstract

Objective To understand the serum levels of 25-hydroxyvitamin D [25 （OH） D] and vitamin A in infants with asthmatic pneumonia during the onset of pneumonia, so as to analyze their correlation with lung function and serum Ig E and to further discover vitamin A and D relationship with infantile asthmatic pneumonia. Methods Fifty-six infants and 50 matched healthy infants and young children who met the diagnostic criteria for asthmatic pneumonia from June to 3 in the Second Affiliated Hospital of Kunming Medical University from 2020 to 2021 were investigated, and enzyme-linked immunoassay was used to check serum 25 （OH） D and Ig E concentration. A pulmonary function meter was used to detect the tidal volume、respiratory rate, Inspiratory time, up to the peak volume of infants with asthmatic infants and young children. The differences in serum 25 （OH） D and vitamin A levels between the two groups of children were analyzed, and the correlation between serum 25 （OH） D and vitamin A levels in children with asthmatic pneumonia and the severity of acute attacks was analyzed. Results The serum 25 （OH） D and vitamin A concentrations of infants and young children in the asthmatic pneumonia group were （18.26±6.64） ng/ml and （0.20±0.09） ng/ml, respectively, which were significantly lower than those of the control group （25.28±3.48） ng/ml, （0.58±0.12） ng/ml, the difference was statistically significant （P < 0.01）. Serum 25 （OH） D levels were positively correlated with the tidal volume, respiratory rate, Inspiratory time , up to the peak volume in infants with onset （r = 0.364, 0.341, 0.369 and 0.548）, and negatively correlated with Ig E （r = -0.549）. Conclusion Children in the asthmatic pneumonia group had vitamin A and D deficiency, and serum vitamin A, 25 （OH） D asthmatic pneumonia episodes were associated.
- Asthmatic pneumonia,
- Infants,
- Vitamin A; Vitamin D,
- Lung function

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References(20)

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