Studies on the Prognosis between Serum sST2 Level and Coronary Heart Disease

Shuo WANG; Yunyan QI; Pu WANG; Yaru WANG; Xiaochan ZHANG; Liu LI

doi:10.12259/j.issn.2095-610X.S20220115

Volume 43 Issue 1

Jan. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(1): 112-117

Shuo WANG, Yunyan QI, Pu WANG, Yaru WANG, Xiaochan ZHANG, Liu LI. Studies on the Prognosis between Serum sST2 Level and Coronary Heart Disease[J]. Journal of Kunming Medical University, 2022, 43(1): 112-117. doi: 10.12259/j.issn.2095-610X.S20220115

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Shuo WANG, Yunyan QI, Pu WANG, Yaru WANG, Xiaochan ZHANG, Liu LI. Studies on the Prognosis between Serum sST2 Level and Coronary Heart Disease[J]. Journal of Kunming Medical University, 2022, 43(1): 112-117. doi: 10.12259/j.issn.2095-610X.S20220115

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Studies on the Prognosis between Serum sST2 Level and Coronary Heart Disease

doi: 10.12259/j.issn.2095-610X.S20220115

1.
Dept. of Cardiology，Shijiazhuang People’s Hospital，Shijiazhuang Hebei 050031
2.
Dept. of Cardiology，Hebei Medical University First Hospital，Shijiazhuang Hebei 050011，China

Received Date: 2021-12-17
Available Online: 2021-12-20
Publish Date: 2022-01-15

Abstract

Abstract

Objective This study was to analyze the prognosis between soluble growth stimulation expressed gene 2 protein （ sST2 ） and the severity of coronary heart disease. Methods 400 patients who needed coronary angiography and stent implantation were selected and divided into low concentration group （< 35 μg/mL）, medium concentration group （35 μg/mL-70 μg/mL）and high concentration group （> 70 μg/mL）according to the concentration of sST2. SYNTAX II score of coronary artery was used in patients and mace events （including cardiac death, myocardial infarction, heart failure, readmission of cardiac causes, target vessel revascularization） were followed up within 360 days after PCI. Results （1） High concentration group had significantly higher SYNTAX II scores than low concentration group and medium concentration group （P < 0.05）. （2） High concentration group had significantly higher mace events than low concentration group and medium concentration after 360 days of PCI （P < 0.05）. Conclusion （1）There is a significant correlation between Serum sST2 Level and SYNTAX II score of coronary artery; （2）There is a significant correlation between Serum sST2 Level and the mace events after 360 days of PCI.
- sST2,
- SYNTAX II score,
- PCI,
- MACE

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References(32)

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